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Assessing nest attentiveness of Common Terns via video cameras and temperature loggers

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Avian Research 2020年第3期11卷 284-301页

作者： j.ffery D.Sullivan Paul R.Marbán j.nnifer M.Mullinax David F.Brinker Peter C.McGowan Carl R.callahan Diann j.Prosser Natural Systems Analysts Winter ParkFL 32789USA Marine Estuarineand Environmental Sciences ProgramUniversity of MarylandCollege ParkMD 20742USA Department of Environmental Science and Technology University of Maryland1443 Animal Sciences BldgCollege ParkMD 20742USA Department of Natural Resources Maryland Natural Heritage ProgramAnnapolisMD 21401USA Chesapeake Bay Field Office U.S.Fish and Wildlife ServiceAnnapolisMD 21401USA U.S.Geological Survey Patuxent Wildlife Research CenterLaurelMD 20708USA.

Background:While nest attentiveness plays a critical role in the reproductive success of avian species,nest attentiveness data with high temporal resolution is not available for many ***,improvements in both video monitoring and temperature logging devices present an opportunity to increase our understanding of this aspect of avian ***:To investigate nest attentiveness behaviors and evaluate these technologies,we monitored 13 nests across two Common Tern(Sterna hirundo)breeding colonies with a paired video camera-temperature logger approach,while monitoring 63 additional nests with temperature loggers *** occurred from May to August of 2017 on Poplar(Chesapeake Bay,Maryland,USA)and Skimmer Islands(Isle of Wight Bay,Maryland,USA).We examined data respective to four times of day:Morning(civil dawn‒11:59),Peak(12:00‒16:00),Cooling(16:01‒civil dusk),and Night(civil dusk‒civil dawn).Results:While successful nests had mostly short duration off-bouts and maintained consistent nest attentiveness throughout the day,failed nests had dramatic reductions in nest attentiveness during the Cooling and Night periods(p0.05),video-monitored nests did have significantly lower clutch sizes(p<0.05).Conclusions:The paired use of iButtons and video ca

关键词： Common Tern iButton Nest attentiveness Sterna hirundo Temperature logger Video monitoring

A phase I radiation dose escalation of stereotactic body radiotherapy for malignant lung tumors

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j.urnal of Biomedical Science and Engineering 2010年第4期3卷 351-358页

作者： Randi j. Cohen Navesh K. Sharma j.an Q. (michael) Yu Lu Wang Mark K. Buyyounouski michael Unger Hossein Borghaei Earl King Walter Scott Elaine callahan Benj.min j. Movsas Steven j. Feigenberg 不详

Obj.ctives: This Phase I study determines the maximum tolerated dose (MTD) of stereotactic body radiotherapy (SBRT) for lung tumors. Methods: Eli- gible patients had biopsy proven cancer with a maxi- mum tumor size ≤ 5 cm. Total doses were escalated from 40 to 48, then to 56 Gy, delivered in 4 equal fractions administered 2 to 3 times per week on an IRB approved protocol. SBRT was administered us- ing 5 to 9 fixed beam arrangements with CT loca- lization. Internal target volumes (ITV) were based on breath hold scans or 4D CT simulation. The planning target volume (PTV) was defined as the ITV with a uniform 5 mm expansion. Dose limiting toxicity (DLT) was defined as any grade 3 or higher toxicity using the Radiation Therapy Oncology Group (RTOG) common toxicity criteria (CTC). Results: Between April 2004 and February 2008, 18 patients received the prescribed treatment (40 Gy n = 6, 48 Gy n = 7, 56 Gy n = 5). Seventeen of 18 patients had non-small cell lung cancer (1 with rectal cancer), four of whom were treated for an oligometastasis. The median age of the patients was 68, while the median Karnofsky performance status was 90. The mean tumor size was 2.6 cm (range 0.9 to 4.5 cm). One grade 3 pulmonary event occurred (at 48 Gy dose level) immediately following treatment with the onset of fever and shortness of breath that responded to antibiotics. No other DLTs occurred. Conclusions: SBRT utilizing patient specific target volumes without gating appears safe. The maximum tolerated dose was not reached.

关键词： Stereotactic Body Radiotherapy Phase I Dose Escalation Prospective Lung Cancer

卒中或短暂性脑缺血发作后的大剂量阿伐他汀治疗

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世界核心医学期刊文摘(神经病学分册) 2006年第12期 2-3页

作者： Amarenco P. Bogousslavsky j. callahan III A. K.M.A.Welch 郭俊 Dr.Rosalind Franklin University of Medicine and Science 3333 Green Bay Rd.North ChicagoIL 60064United States

BACKGROUND:Statins reduce the incidence of strokes among patients at increased risk for cardiovascular disease;whether they reduce the risk of stroke after a recent stroke or transient ischemic attack(TIA)remains to be ***:We randomly assigned 4731 patients who had had a stroke or TIA within one to six months before study entry,had low-density lipoprotein(LDL)cholesterol levels of 100 to 190 mg per deciliter(2.6 to 4.9 mmol per liter),and had no known coronary heart disease to double-blind treatment with 80 mg of atorvastatin per day or *** primary end point was a first nonfatal or fatal ***:The mean LDL cholesterol level during the trial was 73 mg per deciliter(1.9 mmol per liter)among patients receiving atorvastatin and 129 mg per deciliter(3.3 mmol per liter)among patients receiving *** a median follow-up of 4.9 years,265 patients(11.2 percent)receiving atorvastatin and 311 patients(13.1 percent)receiving placebo had a fatal or nonfatal stroke(5-year absolute reduction in risk,2.2 percent;adj.sted hazard ratio,0.84;95 percent confidence interval,0.71 to 0.99;P = 0.03;unadj.sted P = 0.05).The atorvastatin group had 218 ischemic strokes and 55 hemorrhagic strokes,whereas the placebo group had 274 ischemic strokes and 33 hemorrhagic *** five-year absolute reduction in the risk of maj.r cardiovascular events was 3.5 percent(hazard ratio,0.80;95 percent confidence interval,0.69 to 0.92;P = 0.002).The overall mortality rate was similar,with 216 deaths in the atorvastatin group and 211 deaths in the placebo group(P = 0.98),as were the rates of serious adverse *** liver enzyme values were more common in patients taking ***:In patients with recent stroke or TIA and without known coronary heart disease,80 mg of atorvastatin per day reduced the overall incidence of strokes and of cardiovascular events,despite a small increase in the incidence of hemorrhagic stroke.

关键词：阿伐他汀安慰剂患者空白剂暂时性脑缺血短暂性脑缺血出血性卒中

在金属-铬天青S铬合物可见光度法中表面活性剂-诱导变色的机理

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分析试验室 1985年第12期 27-37页

作者： j.H.callahan K.D.Cook 李隆弟

——本文研究在Be2+、Cu2+和Al3+的铬天青S（CAS）络合物可见光度法中,表面活性剂一诱导变色的机理。在阳离子表面活性剂（溴化十六烷基三甲铵、CTAB）存在下,对所有三种金属络合物,均观察到摩尔吸光系数的增加和最大吸收波长的红移。... 详细信息

——本文研究在Be2+、Cu2+和Al3+的铬天青S（CAS）络合物可见光度法中,表面活性剂一诱导变色的机理。在阳离子表面活性剂（溴化十六烷基三甲铵、CTAB）存在下,对所有三种金属络合物,均观察到摩尔吸光系数的增加和最大吸收波长的红移。在非离子表面活性剂（TritonX-100,即TX-100）存在下,对Be2+及Cu2+的络合物,也观察到相同情况。在高离子强度时,发现阴离子表面活性剂（十二烷基硫酸钠,SDS）有类似的效应。在使用TX-100和SDS时,只涉及到严格意义下的胶束相互作用。而在使用CTAB时,既观察到包括表面活性剂单体在內的三元络合物的形成,也观察到了胶束相互作用,即在低浓度CTAB时,形成具有明确组成的络合物;到临界胶束浓度以上时,则为胶束相互作用。所有“表面活性剂增敏”体系的光谱都很类似,意味着生色团在三元络合物中和在胶束中有类似的微环境。

关键词：表面活性剂水泥外加剂络合物配位化合物胶束化金属金属材料光度法铬天青

Developing one-dimensional implosions for inertial confinement fusion science

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High Power Laser Science and Engineering 2016年第4期4卷 1-7页

作者： j.L.Kline S.A.Yi A.N.Simakov R.E.Olson D.C.Wilson G.A.Kyrala T.S.Perry S.H.Batha E.L.Dewald j.E.Ralph D.j.Strozzi A.G.MacPhee D.A.callahan D.Hinkel O.A.Hurricane R.j.Leeper A.B.Zylstra R.R.Peterson B.M.Haines L.Yin P.A.Bradley R.C.Shah T.Braun j.Biener B.j.Kozioziemski j.D.Sater M.M.Biener A.V.Hamza A.Nikroo L.F.Berzak Hopkins D.Ho S.LePape N.B.Meezan D.S.Montgomery W.S.Daughton E.C.Merritt T.Cardenas E.S.Dodd Los Alamos National Laboratory Lawrence Livermore National Laboratory

Experiments on the National Ignition Facility show that multi-dimensional effects currently dominate the implosion performance. Low mode implosion symmetry and hydrodynamic instabilities seeded by capsule mounting features appear to be two key limiting factors for implosion performance. One reason these factors have a large impact on the performance of inertial confinement fusion implosions is the high convergence required to achieve high fusion *** tackle these problems, a predictable implosion platform is needed meaning experiments must trade-off high gain for performance. LANL has adopted three main approaches to develop a one-dimensional(1D) implosion platform where 1D means measured yield over the 1D clean calculation. A high adiabat, low convergence platform is being developed using beryllium capsules enabling larger case-to-capsule ratios to improve symmetry. The second approach is liquid fuel layers using wetted foam targets. With liquid fuel layers, the implosion convergence can be controlled via the initial vapor pressure set by the target fielding temperature. The last method is double shell targets. For double shells, the smaller inner shell houses the DT fuel and the convergence of this cavity is relatively small compared to hot spot ignition. However,double shell targets have a different set of trade-off versus advantages. Details for each of these approaches are described.

关键词： beryllium capsules double shells inertial confinement fusion liquid layers

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国际医学放射学杂志 2009年第3期 275-276页

作者： M.j.callahan L.Poznauskis D.Zaurakowski G.A.Taylor 李艳辉 Department of Radiology Children's Hospital Boston300 Longwood AveBostonMA 02115USA

目的调查静脉注射非离子型对比剂的相关反应在大组患儿中的发生率和严重程度。方法回顾三级保健儿科医院连续7年的电子记录,选择CT和排泄性尿路成像中使用碘佛醇的病人,有12494例年龄小于21岁的病人注射了碘佛醇,其中男性6600例,女性589... 详细信息

目的调查静脉注射非离子型对比剂的相关反应在大组患儿中的发生率和严重程度。方法回顾三级保健儿科医院连续7年的电子记录,选择CT和排泄性尿路成像中使用碘佛醇的病人,有12494例年龄小于21岁的病人注射了碘佛醇,其中男性6600例,女性5894例。根据美国放射学院制订的标准,对比剂反应分为轻、中、重度。

关键词：非离子型碘对比剂非离子型对比剂发生率病人静脉注射反应

多巴酚丁胺负荷超声心动图正常患者的预后以及不良事件的预测因素:3014例患者的长期随访

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世界核心医学期刊文摘(心脏病学分册) 2007年第6期 42-42页

作者： Chaowalit N McCully R.B callahan M.j.P.A.Pellikka 马超 Division of Cardiovascular Diseases Mayo Clinic200 First Street SWRochesterMN 55905United States

目的:运动超声心动图正常预示着患者的预后良好。多巴酚丁胺负荷超声心动图(DSE)是患有并存病而不能行运动试验者的备选方法。评估DSE正常患者的

关键词：多巴酚丁胺负荷超声心动图不良事件长期随访预测因素患者预后

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儿童胸部CT诊断参考值范围:进展与应用

国际医学放射学杂志 2017年第5期 591-591页

作者： K.j.Strauss M.j.Goske A.j.Towbin D.Sengupta M.j.callahan K.Darge 王佳红 Department of Radiology Cincinnati Children’s Hospital Medical Center

摘要目的基于儿科病人胸部的大小来确定诊断参考值范围,并开发基于患儿体型大小和各CT设备射线输出计算的CT设备特异性平均体型特异性剂量评估(SSDE)。材料

关键词：参考值减低因子剂量指数 CT

An Alzheimer's Disease-Relevant Presenilin-1 Mutation Augments Amyloid-Beta-Induced Oligodendrocyte Dysfunction

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神经损伤与功能重建 2011年第2期6卷 128-141页

作者： MAYA K.DESAI BRENDAN j.GUERCIO WADE C.NARROW WILLIAM j.BOWERS Department of Pharmacology and Physiology University of Rochester School of Medicine and DentistryRochesterNew York Center for Neural Development and Disease University of Rochester School of Medicine and DentistryRochesterNew York Department of Microbiology and Immunology University of Rochester School of Medicine and DentistryRochesterNew York Department of Neurology University of Rochester School of Medicine and DentistryRochesterNew York

研究表明,家族性阿尔茨海默病(FAD)患者处于无症状或临床前阶段时,脑白质即出现病理改变。此种改变在髓鞘破坏及阿尔茨海默病(AD)病理生理中的作用有待进一步研究阐明。笔者前期研究证实,三重转基因AD小鼠(人淀粉前体蛋白基因的Swedish... 详细信息

研究表明,家族性阿尔茨海默病(FAD)患者处于无症状或临床前阶段时,脑白质即出现病理改变。此种改变在髓鞘破坏及阿尔茨海默病(AD)病理生理中的作用有待进一步研究阐明。笔者前期研究证实,三重转基因AD小鼠(人淀粉前体蛋白基因的Swedish突变,早老素-1 M146V(PS1M146V)敲入突变及tauP301L突变)表现出类似FAD患者的髓鞘破坏,Aβ1-42促进了白质病变。本研究离体实验证实,PS1M146V变异导致小鼠少突胶质前体细胞在分化过程中易出现类似Aβ1-42诱导的变化。PS1M146V的表达损伤少突胶质前体细胞的功能并影响髓鞘碱性蛋白的分布,暴露于Aβ1-42加重此影响。由PS1M146V及Aβ1-42导致的髓鞘破坏及髓鞘碱性蛋白在亚细胞结构中的误定位可被TWS119(糖原合成激酶(GSK)-3β抑制剂)抑制,提示GSK-3β激酶活动在此病理过程中有重要作用。综上所述,本研究有助于增加对AD早期无症状阶段,由PS1M146V及Aβ1-42导致少突胶质细胞功能异常及髓鞘损伤的机制的理解,并提供了针对少突胶质细胞预防AD相关白质病变的新的治疗靶点。

关键词：阿尔茨海默病白质髓磷脂少突胶质细胞髓鞘碱性蛋白淀粉β样蛋白早老素-1 3重转基因AD