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Model-Based Identification of Mechanical Characteristics of Sinosaurus(Theropoda) Crests

Acta Geologica Sinica(English Edition) 2015年第1期89卷 1-11页

作者： XING Lida WANG Yikun Eric SNIVELY ZHANG Jianping DONG Zhiming michael E.burns Philip J.CURRIE School of the Earth Sciences and Resources China University of Geosciences Auckland Bioengineering Institute The University of Auckland Department of Mechanical Engineering Ohio University Institute of Vertebrate Paleontology and Paleoanthropology Chinese Academy of Sciences Department of Biological Sciences University of Alberta Alberta T6G 2E9 Canada

The paired cranial crests of Sinosaurus （Theropoda） have been hypothesized as too weak to resist mechanical loads during combat. Finite element analysis （FEA） is used to test this hypothesis, first with geometry obtained through direct laser scanning of a well-preserved fossil of the crest, and then with two conceptual FE models of both crests analyzing the structure-deformation effects of fenestration. In the original fossil model, under direct loading on the dorsal faces of the crest, we found that the areas surrounding cavities on the crest experience shear stress that implies a high chance of material failure - the fracture of bone. In the conceptual model, a series of computational studies were conducted with varying loading directions. One simulation found that the shear stress and strain in the material around the cavity presented more deformation compared with the conceptual model without the cavities, and under this morphologically realistic scenario the loading conditions would result in local bone fractures. These model-based computational results indicate that the crest could not resist high loads, because it could not effectively decentralize the loading stress. Future investigations need to focus on more comprehensive computational experiments with more conditions, e.g. dynamical loading conditions, and direct palaeontological evidence.

关键词： Dinosauria Sinosaurus behavior finite element analysis

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Braincase Anatomy of the Basal Theropod Sinosaurus from the Early Jurassic of China

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Acta Geologica Sinica(English Edition) 2014年第6期88卷 1653-1664页

作者： XING Lida Ariana PAULINA-CARABAJAL Philip J.CURRIE XU Xing ZHANG Jianping WANG Tao michael E.burns DONG Zhiming School of the Earth Sciences and Resources China University of Geosciences Museo Carmen Funes Consejo Nacional de Investigaciones Científicas y TecnológicasAv.Córdoba 55 (8318)Plaza Huincul Neuquén Argentina University of Alberta CW405 Biological Sciences BuildingEdmonton Alberta T6G 2E9 Canada Institute of Vertebrate Paleontology and Paleoanthropology Chinese Academy of Sciences Lufeng Land and Resources Bureau

The neuroanatomy of the mid-sized theropod Sinosaurus triassicus from the Lower Jurassic Lufeng Formation, Lufeng Basin in Yunnan Province, China was studied using X-ray computed tomography. The braincase is characterized by a large supraoccipital knob that is capped by a posterior projection of the parietal and two external foramina for the caudal middle cerebral vein, which is completely enclosed by the supraoccipital. The basicranium has well defined, short basipterygoid processes that project ventral to the basal tubera. The basisphenoid is expanded, projects posteroventrally, and is pierced by four pneumatic recesses. The endocranial morphology resembles that observed in other basal theropods—in particular some allosauroids—and has a strongly marked pontine flexure and a large dorsal expansion. The inner ear morphology is also similar to that observed in other basal theropods, with slender semicircular canals. The anterior semicircular canal is 20% larger than the posterior semicircular canal, and the angle formed between them is less than 90° when seen in dorsal view.

关键词： Neuroanatomy paleoneurology Dinosaur inner ear pneumaticity Early Jurassic Yunnan

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A redescription of the ichnospecies Koreanaornis anhuiensis(Aves) from the Lower Cretaceous Qiuzhuang Formation at Mingguang city, Anhui Province, China

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Journal of Palaeogeography 2018年第1期7卷 58-65页

作者： Li-Da Xing Yuan-Chao Hu Jian-Dong Huang Qing He Martin G.Lockley michael E.burns Jun Fang State Key Laboratory of Biogeology and Environmental Geology China University of Geosciences Beijing 100083China School of Earth Sciences and Resources China University of GeosciencesBeijing 100083China State Key Laboratory of Palaeobiology and Stratigraphy Nanjing Institute of Geology and PalaeontologyChinese Academy of SciencesNanjing 210008Jiangsu ProvinceChina Anhui Geological Museum Hefei 230031Anhui ProvinceChina School of Resources and Environmental Engineering Anhui UniversityHefei 230039Anhui Province China Dinosaur Trackers Research Group University of Colorado DenverPO Box 173364DenverCO 80217USA Department of Biology Jacksonville State University700Pelham RdJacksonvilleFL 36265USA

The Cretaceous bird trackway originally labeled Aquatilavipes anhuiensis, in 1994, had previously been examined, photographed and replicated, but never described or illustrated in detail. However, it has been part of a widening discussion about the distribution of Aquatilavipes and Koreanaornis in China(and Korea). Here we illustrate and formally describe the holotype in detail and assign it to Koreanaornis(Koreanaornis anhuiensis) as informally proposed by previous authors. We also demonstrate that most authenticated reports of Koreanaornis, including the Anhui occurrence, are from the Lower Cretaceous, not from the Upper Cretaceous as previously reported.

关键词： Lower Cretaceous Ichnospecies Koreanaornis Aquatilavipes Qiuzhuang Formation Anhui Province

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多媒体系统与信息集散

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情报科学 1994年第6期15卷 53-58页

作者： Nicholas I.Benimoff michael J.burns 张海燕美

在过去的几十年中,计算机技术以比许多可以想象得到的速度高得多的多的速度一直在发展着。不断进取的信息传递能力已导致了在时间,地点,原因和人们如何通信等方面的诸多变化。在计算机能力方面的发展改变了我们的工作情况及个人生活的... 详细信息

在过去的几十年中,计算机技术以比许多可以想象得到的速度高得多的多的速度一直在发展着。不断进取的信息传递能力已导致了在时间,地点,原因和人们如何通信等方面的诸多变化。在计算机能力方面的发展改变了我们的工作情况及个人生活的情况。

关键词：多媒体系统信息集散计算机

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法国与德雷福斯事件

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作者： M.·伯恩斯 michael·burns

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新式冷却法

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电子产品世界 2011年第5期18卷 63-64页

作者： michael burns RS Components

电子工程界在有效利用能源领域扮演着至关重要的角色,为能源的开采、运输、消耗和控制提供先进科技,造福大众。随着社会愈发重视节能,电子工程界更起着越来越重要的作用。

关键词：冷却法能源领域电子工程有效利用

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Impact of conditioning regimen on peripheral blood hematopoietic cell transplant

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World Journal of Clinical Oncology 2019年第2期10卷 86-97页

作者： michael burns Anurag K Singh Carrie C Hoefer Yali Zhang Paul K Wallace George L Chen Alexis Platek Timothy B Winslow Austin J Iovoli Christopher Choi Maureen Ross Philip L McCarthy Theresa Hahn Department of Medicine Roswell Park Comprehensive Cancer Center Department of Radiation Medicine Roswell Park Comprehensive Cancer Center Department of Flow Cytometry Roswell Park Comprehensive Cancer Center Center for Immunotherapy Roswell Park Comprehensive Cancer Center

AIM To investigate infused hematopoietic cell doses and their interaction with conditioning regimen intensity +/-total body irradiation(TBI) on outcomes after peripheral blood hematopoietic cell transplant(PBHCT).METHODS Our retrospective cohort included 247 patients receiving a first, T-replete, human leukocyte antigen-matched allogeneic PBHCT and treated between 2001 and2012. Correlations were calculated using the Pearson product-moment correlation coefficient. Overall survival and progression free survival curves were generated using the Kaplan-Meier method and compared using the log-rank *** Neutrophil engraftment was significantly faster after reduced intensity TBI based conditioning [reduced intensity conditioning(RIC) + TBI] and > 4 × 10~6 CD34+cells/kg infused. A higher total nucleated cell dose led to a higher incidence of grade II-IV acute graft-versus-host disease in the myeloablative + TBI regimen group(P = 0.03), but no significant difference in grade III-IV graft-versus-host disease. A higher total nucleated cell dose was also associated with increased incidence of moderate/severe chronic graft-versus-host disease, regardless ofconditioning regimen. Overall and progression-free survival were significantly better in patients with a RIC + TBI regimen and total nucleated cell dose > 8 ×10~8/kg(3 years, overall survival: 70% vs 38%, P = 0.02, 3 years, progression free survival: 64% vs 38%, P = 0.02).CONCLUSION TBI and conditioning intensity may alter the relationship between infused cell doses and outcomes after PBHCT. Immune cell subsets may predict improved survival after unmanipulated PBHCT.

关键词： Total body radiation Peripheral blood hematopoietic cell transplant Total nucleated dose Neutrophil engraftment Graft-versus-host-disease

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TACE联合干扰素可以安全有效地治疗肝切除术后的肝癌患者

TACE联合干扰素可以安全有效地治疗肝切除术后的肝癌患者

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第十五届全国肝癌学术会议

作者：左朝晖夏蛮刘景诗邱晓昕雷雄许若才刘寒春李建良李永国李清龙肖华洪源王晓红朱海珍吴群峰 michael burns Chen Liu 中南大学湘雅医学院附属肿瘤医院暨湖南省肿瘤医院胃十二指肠胰腺外科肝癌转化医学中心中南大学湘雅二医院普通外科国佛罗里达大学病理学免疫学与实验医学研究中心

＜正＞目的术后复发是HBV相关性肝癌患者术后死亡的主要原因。目前,已经报道了一些方法可以减少术后复发率。我们的研究目的主要是比较单独运用TACE与TACE联合干扰素治疗对于肝切除术后的肝癌患者的临床疗效。方法我们回顾性分析了从200...

＜正＞目的术后复发是HBV相关性肝癌患者术后死亡的主要原因。目前,已经报道了一些方法可以减少术后复发率。我们的研究目的主要是比较单独运用TACE与TACE联合干扰素治疗对于肝切除术后的肝癌患者的临床疗效。方法我们回顾性分析了从2001年至2008年间228例HBV相关性肝癌经肝切除术后的患者的临床数据,并把这些患者分为了单纯TACE治疗组和TACE联合干扰素治疗组,其中TACE方案是联合了5-FU、顺铂、丝裂霉素C和碘化油的化疗方案。然后我们评价分析了两组患者的术后复发率、无病生存期、总生存期以及复发风

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术前N-乙酰半胱氨酸预防接受CABG手术的高危患者的肾功能障碍：随机对照试验

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美国医学会杂志（中文版） 2006年第3期25卷 182-182页

作者： Karen E. A. burns michael W. A. Chu Richard J. Novick 李呈亿（译）

背景：肾功能障碍为心肺转流（cardiopulmonary bypass，CPB）下冠状动脉旁路移植手术（coronary artery bypass graft，CABG）的并发症。该并发症与患者发病和死亡增加相关。N-乙酰半胱氨酸，一种抗氧化剂和血管扩张剂，可抵消肾缺血... 详细信息

背景：肾功能障碍为心肺转流（cardiopulmonary bypass，CPB）下冠状动脉旁路移植手术（coronary artery bypass graft，CABG）的并发症。该并发症与患者发病和死亡增加相关。N-乙酰半胱氨酸，一种抗氧化剂和血管扩张剂，可抵消肾缺血、缺氧。

关键词：冠状动脉旁路移植手术 N-乙酰半胱氨酸肾功能障碍高危患者随机对照试验 CABG 预防术前 artery 血管扩张剂

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Novel Approach to the Rapid Differentiation of Common Prunus Allergen Species by PCR Product Melt Analysis

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Food and Nutrition Sciences 2016年第10期7卷 920-926页

作者： Gavin Nixon Laurie Hall Timothy Wilkes michael Walker Malcolm burns Science and Innovation LGC Ltd. Teddington England

Food allergies represent a clear threat to the general health and wellbeing of those affected which place increasing pressure on food producers and regulatory authorities. Current analytical techniques typically find difficulties distinguishing between closely related Prunus species which include almond (Prunus dulcis), an EU listed allergenic species. This study describes a proof of principle real-time PCR approach utilising DNA melt analyses that targets the internal transcribed spacer (ITS) sequence to differentiate between a panel of Prunus test species. The method was successfully applied to the characterisation of a commercial paprika sample suspected of having being adulterated with almond, referred to the UK Government Chemist in 2015 in its advisory capacity. Subject to further validation work, the method appears to specifically amplify Prunus species and is capable of discrimination based on the resultant melt profiles. The developed method provides analysts with a simple and broad molecular tool to identify common Prunus species for food authenticity and allergen testing purposes. Initial development work demonstrates a promising approach with the potential to improve discrimination between Prunus species not easily resolved by routine analytical methods.

关键词： Allergens Melt Analysis Prunus Speciation Real-Time PCR

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