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Feasibilit.,efficacy,and safet. of animal-assist.d act.vit.es wit. visit.ng dogs in inpat.ent.pediat.ic oncology

World Journal of Pediat.ics 2024年第9期20卷 915-924页

作者： Kat.a St.ff Maximilian Grasemann Kira ost.rmann Sarah Christ.na Goret.ki Pet.r-michael Rat. Dirk Reinhardt.michael M.Schündeln Pediat.ic Hemat.logy and oncology Department of Pediatrics IIIUniversity of Duisburg-EssenHufelandstr.5545122EssenGermany Depart.ent.of Psychology Medical School HamburgHamburgGermany Pediat.ic Infect.ology Department of Pediatrics IUniversity of Duisburg-EssenEssenGermany Inst.t.t. of Medical Microbiology University of Duisburg-EssenEssenGermany

Background Childhood cancer ent.ils a heavy burden for pat.ent. and t.eir *** advances in overall survival rat.s have increasingly brought.long-t.rm qualit. of life int. ***-assist.d act.vit.es(AAAs)have long been hypot.esized t. alleviat. t.e burden on pediat.ic pat.ent. and t.eir peers in t.e hospit.l ***,t.eir use in inpat.ent.pediat.ic oncology has been a sensit.ve issue mainly due t. t.e fear of infect.ons,result.ng in a lack of *** st.dy present. dat. on t.e feasibilit.,safet.,and efficacy of AAAs from a single German *** Bet.een 2018 and 2022,60 pat.ent.(median age=10.3 years)diagnosed wit. malignancy and undergoing t.eat.ent.were visit.d by an int.rvent.on dog(t.t.l visit.=100).Pat.ent. were screened for infect.ons as per hospit.l policy,wit. addit.onal microbiological t.st.ng performed based on *** dog was screened for human pat.ogens and *** dat. and hospit.lizat.ons were analyzed from t.o mont.s prior t. t.e first.visit.unt.l t.o mont.s aft.r t.e last.*** of being in t.e hospit.l,bot. wit. and wit.out.planned animal-assist.d int.rvent.ons and pre-and post.int.rvent.on st.t. st.ess,were measured using a validat.d visual analogue scale(0-10).Result. Pat.ent. benefit.d from AAAs,showing increased accept.nce of being in t.e hospit.l(median:7.25 vs.4.50,Pt.t. st.ess rat.ngs one hour aft.r t.e visit.compared t. one hour before t.e visit.1.00 vs.4.25,Pt.e int.rvent.on did not.result.in an increased number of infect.ons or unplanned hospit.lizat.ons,and no zoonoses were *** microbial screening t.st. of t.e dog were *** AAAs wit. visit.ng dogs in inpat.ent.pediat.ic oncology are feasible and *** t.ey hold promise for enhancing pat.ent.’well-being,furt.er prospect.ve st.dies are needed.

关键词： Animal-assist.d act.vit.es Animal-assist.d int.rvent.ons Animal-assist.d t.erapy Feasibilit. Infect.on cont.ol Inpat.ent.pediat.ic oncology Safet. St.ess response t.erapy dog Visit.ng dog

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Evaluat.on of disease burden and sympt.m scores in pat.ent. wit. acut. at.ial fi brillat.on in t.e emergency depart.ent

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World Journal of Emergency Medicine 2024年第5期15卷 397-400页

作者： Nikola Schüt. Dominik Rot. michael Prinz Filippo Cacioppo Sebast.an Schnaubelt.Alexander o.Spiel Hans Domanovit. Harald Herkner Depart.ent.of Emergency Medicine Medical University of ViennaVienna 1090Austria Depart.ent.of Emergency Medicine Clinic OttakringVienna 1160Austria

At.ial fibrillat.on(AF)is a major public healt. problem and poses a subst.nt.al economic burden on healt.care syst.ms worldwide.[1-4]t.e emergency depart.ent.ED)serves as t.e first.point.of cont.ct.wit. t.e healt.care syst.m and plays a key role in t.e management.of pat.ent. wit. AF,which account. for 3%-10%of all hospit.l admissions.[5]t.eat.ent.plans are oft.n discussed and init.at.d at.t.e ED.

关键词： pat.ent. at.ial acut.

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t.e Impact.of opioid Drugs on Memory and ot.er Cognit.ve Funct.ons: A Review

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Journal of Biosciences and Medicines 2024年第4期12卷 264-287页

作者： Mason t. Bennet. Yuliya Modna Dev Kumar Shah School of Biomedical Sciences Trinity Medical Sciences University Kingstown Saint Vincent and Grenadines Depart.ent.of Physiology Trinity Medical Sciences University Kingstown Saint Vincent and Grenadines

Background and Purpose: opioids, used for cent.ries t. alleviat. pain, have become a double-edged sword. While effect.ve, t.ey come wit. a host.of adverse effect., including memory and cognit.on impairment. t.is review delves int. t.e impact.of opioid drugs on cognit.ve funct.ons, explores underlying mechanisms, and invest.gat.s t.eir prevalence in bot. medical care and illicit.drug use. t.e ult.mat. goal is t. find ways t. mit.gat. t.eir pot.nt.al harm and address t.e ongoing opioid crisis. Met.ods: We sourced dat. from PubMed and Google Scholar, employing search combinat.ons like “opioids,” “memory,” “cognit.on,” “amnesia,” “cognit.ve funct.on,” “execut.ve funct.on,” and “inhibit.on.” our focus was on English-language art.cles spanning from t.e incept.on of t.ese dat.bases up t. t.e present. Result.: t.e lit.rat.re consist.nt.y reveals t.at.opioid use, part.cularly at.high doses, adversely affect. memory and ot.er cognit.ve funct.ons. Longer deliberat.on t.mes, impaired decision-making, impulsivit., and behavioral disorders are common consequences. Chronic high-dose opioid use is associat.d wit. condit.ons such as amnesiac syndrome (oAS), post.operat.ve cognit.ve dysfunct.on (PoCD), neonat.l abst.nence syndrome (NAS), depression, anxiet., sedat.on, and addict.on. Alarming t.ends show increased opioid use over recent.decades, amplifying t.e risk of t.ese out.omes. Conclusion: opioids cast.a shadow over memory and cognit.ve funct.on. t.ese effect. range from amnesiac effect., lessened cognit.ve funct.on, depression, and more. Cont.ibut.ng fact.rs include over-prescript.on, misuse, misinformat.on, and prohibit.on policies. Focusing on correct.informat.onal campaigns, removing punit.ve policies, and focusing on harm reduct.on st.at.gies have been shown t. lessen t.e abuse and use of opioids and t.us helping t. mit.gat. t.e adverse effect. of t.ese drugs. Furt.er research int. t.e impact. of opioids on cognit.ve abilit.es is also needed as t.ey are well demonst.at.d in

关键词： opioids Memory Cognit.on Pain

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Exploring t.e associat.ons bet.een skelet.l muscle echogenicit. and physical funct.on in aging adult.:A syst.mat.c review wit. met.-analyses

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Journal of Sport.and Healt. Science 2024年第6期13卷 820-840页

作者： Dust.n J.oranchuk St.phan G.Bodkin Kat.e L.Boncella michael o.Harris-Love Muscle Morphology Mechanicsand Performance LaboratoryDepartment of Physical Medicine and RehabilitationUniversity of Colorado Anschutz Medical CampusAuroraCO 80045USA Depart.ent.of Physical t.erapy

Background:Assessment.and quant.ficat.on of skelet.l muscle wit.in t.e aging populat.on is vit.l for diagnosis,t.eat.ent.and injury/disease *** clinical availabilit. of assessing muscle qualit. t.rough diagnost.c ult.asound present. an opport.nit. t. be ut.lized as a screening t.ol for funct.on-limit.ng ***,relat.onships bet.een muscle echogenicit. and clinical funct.onal assessment. require aut.orit.t.ve ***,we aimed t.(a) synt.esize t.e lit.rat.re t. assess t.e relat.onships bet.een skelet.l muscle echogenicit. and physical funct.on in older adult.(≥60 years),(b) perform pooled analyses of relat.onships bet.een skelet.l muscle echogenicit. and physical funct.on,and(c) perform sub-analyses t. det.rmine bet.een-muscle ***:CINAHL,Embase,MEDLINE,PubMed,and Web of Science dat.bases were syst.mat.cally searched t. ident.fy art.cles relat.ng skelet.l muscle echogenicit. t. physical funct.on in older ***-of-bias assessment. were conduct.d along wit. funnel plot.***-analyses wit. and wit.out.sub-analyses for individual muscles were performed ut.lizing Fisher's Z t.ansformat.on for t.e most.common measures of physical ***'s Z was back-t.ansformed t. Pearson's r for ***:Fift.-one art.cles(n=5095,female=~2759,male=~2301,72.5± 5.8 years,mean±SD(1 st.dy did not.provide sex descript.rs))were ext.act.d for review,wit. previously unpublished dat. obt.ined from t.e aut.ors of 13 *** rect.s femoris(n=34) and isomet.ic knee ext.nsion st.engt.(n=22) were t.e most.accessed muscle and physical qualit.es,*** relat.onship bet.een quadriceps echogenicit. and knee ext.nsor st.engt. was moderat.(n=2924,r=-0.36(95% confidence int.rval:-0.38 t.-0.32),p t. all ot.er met.-analyses(grip st.engt.,walking speed,sit.t.-st.nd,t.med up-and-go) result.ng in slight.y weaker correlat.ons(r:-0.34 t.-0.23,all p t.rmined minimal differences in predict.

关键词： Correlat.ons Echo int.nsit. Elderly Int.amuscular fat St.engt.

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A General Analyt.c Approximat.on t.chnique for t.e Modified Bessel Funct.ons wit. Fract.onal order Iv (x), Applied t. I1/6(x) and I1/7(x)

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Advances in Pure Mat.emat.cs 2024年第9期14卷 768-777页

作者： Jorge olivares Pablo Mart.n Maria t. Veliz Depart.ment. de Mat.mt.cas Universidad de Antofagasta Antofagasta Chile Depart.ment. de Fsica Universidad de Antofagasta Antofagasta Chile

A general t.chnique t. obt.in simple analyt.c approximat.ons for t.e first.kind of modified Bessel funct.ons. t.e general procedure is shown, and t.e paramet.r det.rminat.on is explained t.rough t.e applicat.ons t. t.is part.cular case I1/6(x)and I1/7(x). In t.is way, it.shows how t. apply t.e t.chnique t. any part.cular orderν, in order t. obt.in an approximat.on valid for any posit.ve value of t.e variable x. In t.e present.met.od power series and asympt.t.c expansion are simult.neously used. t.e t.chnique is an ext.nsion of t.e mult.point.quasirat.onal approximat.on met.od, MPQA. t.e main idea is t. look for a bridge funct.on bet.een t.e power and asympt.t.c expansion of t.e I1/6(x), and similar procedure for I1/7(x). t. perform t.is, rat.onal funct.ons are combined wit. hyperbolic ones and fract.onal powers. t.e number of paramet.rs t. be det.rmined for each case is four. t.e maximum relat.ve errors are 0.0049 for ν=1/6, and 0.0047 for ν=7. However, t.ese relat.ve errors decrease out.ide of t.e small region of t.e variables, wherein t.e maximum relat.ve errors are reached. t.ere is a clear advant.ge of t.is procedure compared wit. any ot.er ones.

关键词： Bessel Funct.ons Power Series Asympt.t.c Expansion MPQA t.chnique

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Developing a mult.-met.od approach t. ident.fying e-scoot.r hazard hot.pot.

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Journal of t.affic and t.ansport.t.on Engineering(English Edit.on) 2024年第4期11卷 667-680页

作者： michael Hardinghaus Simon Nieland Rebekka oost.ndorp Jan Weschke German Aerospace Cent.r(DLR)Inst.t.t. of t.ansport.Research Berlin 12489Germany

In recent.years,e-scoot.rs have been int.oduced in many European *** several places we have wit.essed a rapid upt.ke of t.is new mode of t.ansport.mainly as a result.of public sharing schemes.A number of incident.,injuries and even fat.lit.es have given rise t. quest.ons regarding t.e safet. of t.ese *** quest.ons are being researched mainly using official crash dat. and dat. specifying injuries and hospit.l *** now,t.e research has focused on invest.gat.ng t.pical injury pat.erns and est.mat.ng risk *** lit.le is known about.exact.y where conflict. and crashes *** of hazard hot.pot. is crucial when invest.gat.ng risk levels and improving safet. for all road ***,t.is paper develops an approach t. invest.gat.ng locat.ons wit. pot.nt.ally dangerous int.ract.ons wit.in t.e act.ve mobilit. syst.m in t.e cit. of *** approach consist. of explorat.ve expert.int.rviews,an online poll,and quant.t.t.ve *** t.e lat.er we combine t.ree ***,we research crash hot.pot. using official ***,we use dat. based on accelerat.on sensors from cyclist.'smart.hones t. find locat.ons of sudden ***,we use t.ip dat. from t.e operat.rs of escoot.r sharing *** informat.on gat.ered is used in a conclusive expert.workshop t. ident.fy hazard *** show t.at.many of t.e conflict. wit. pedest.ians are caused by parked ***,e-scoot.r t.ips are concent.at.d in t.e inner cit. and along specific *** moving t.affic,various dat. sources are used t. ident.fy hot.pot. at.int.rsect.ons and in areas bet.een *** present.research lays t.e foundat.on for import.nt.furt.er st.dies t. invest.gat. int.ract.ons at.hot.pot. in det.il by det.rmining nine specific locat.ons in t.e cit. of Berlin.

关键词： E-scoot.r Accident. Crashes Act.ve mobilit. Micromobilit. Road safet.

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Mult.ple sclerosis drug repurposing for neuroregenerat.on

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Neural Regenerat.on Research 2024年第3期19卷 507-508页

作者： Pet.r Göt.le michael Diet.ich Pat.ick Küry Depart.ent.of Neurology Medical FacultyHeinrich-Heine UniversityDüsseldorfGermany

Mult.ple sclerosis(MS)is an aut.immune disorder of t.e cent.al nervous syst.m(CNS)and is primarily charact.rized by immune cell infilt.at.on leading t. relapses followed by remission phases and a disease course t.rning progressive over t.me wit. neurodegenerat.ve processes t.king over(Amin and Hersh,2023).of not.,beyond relapse-associat.d worsening early in disease progression independent.of relapse act.vit. may arise independent.y of relapse act.vit. and can occur in all ***-mediat.d damage of myelin sheat.s and t.e subsequent.loss of mat.re oligodendrocyt.s are result.ng in impaired axonal int.grit.,neurodegenerat.on and account. for irreversible neuronal damage(Kuhlmann et.al.,2023).t.e current.landscape of available disease-modifying t.erapies comprises mainly immunomodulat.ry drugs t.at.effect.vely diminish relapses and slow down progression at.t.e onset.form of t.e disease,namely relapsing MS(RMS).In t.is regard,a number of drugs have been approved as disease-modifying t.erapies for MS by US Food and Drug Administ.at.on and European Medicines Agencies(Box 1).

关键词： drugs impaired irreversible

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Charact.rizat.on of Deplet.d Hydrocarbon Reservoir AA-01 of KoKA Field in t.e Niger Delt. Basin for Sust.inable Sub-Sea Carbon Dioxide St.rage

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哈尔滨工程大学学报（英文版） 2024年第3期23卷 544-564页

作者： Pat.ick A.Eigbe olat.nbosun o.Ajayi olabode t.olakoyejo Adekunle o.Adelaja Depart.ent.of Mechanical Engineering University of LagosAkokaLagos State100213Nigeria Depart.ent.of Aerospace Engineering Lagos State UniversityEpe CampusLagos State106101Nigeria

t.is st.dy charact.rized t.e AA-01 deplet.d hydrocarbon reservoir in t.e KoKA field, Niger Delt., using a mult.dimensional approach. t.is invest.gat.on involved dat. validat.on analysis, evaluat.on of sit. suit.bilit. for Co_(2) st.rage, and composit.onal simulat.on of hydrocarbon component.. t.e primary object.ve was t. det.rmine t.e init.al component. and behavior of t.e hydrocarbon syst.m required t. opt.mize t.e inject.on of Co_(2) and accompanying impurit.es, est.blishing a robust.basis for subsequent.sequest.at.on effort. in t.e six wells in t.e deplet.d KoKA AA-01 reservoir. t.e process, simulat.d using indust.y soft.are such as ECLIPSE, PVt., SCAL, and Pet.el, included a composit.onal fluid analysis t. confirm t.e pressure volume t.mperat.re(PVt. hydrocarbon phases and component.. t.is involved performing a mat.rial balance on t.e qualit. of t.e measured dat. and mat.hing t.e init.al reservoir pressure wit. t.e supplied dat. source. t.e composit.onal PVt.analysis adopt.d t.e Peng–Robinson equat.on of st.t. t. model fluid flow in porous media and est.mat. t.e necessary number of phases and component. t. describe t.e syst.m accurat.ly. Result. from t.is invest.gat.on indicat. t.at.t.e KoKA AA-01 reservoir is suit.ble for Co_(2)sequest.at.on. t.is conclusion is based on t.e reservoir's good qualit., evidenced by an average porosit. of 0.21 and permeabilit. of 1 111.0 mD, a measured lit.ological dept. of 9 300 ft. and charact.rist.c reservoir – seal propert.es correlat.d from well logs. t.e st.dy confirmed t.at.volumet.ic behavior predict.ons are direct.y linked t. composit.onal behavior predict.ons, which are essent.al during reservoir init.alizat.on and dat. qualit. checks. Addit.onally, it.highlight.d t.at.a safe design for Co_(2) st.rage relies on accurat.ly represent.ng mult.phase behaviour across wide-ranging pressure–t.mperat.re–composit.on condit.ons.

关键词： Carbon capt.re Co_(2)sequest.at.on Geological st.rage Geo-mechanical modeling Mult.phase flow Niger Delt.

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Geomet.ic Programming for Nonlinear Sat.llit. Buffer Net.orks Wit. t.me Delays under L_(1)-Gain Performance

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IEEE/CAA Journal of Aut.mat.ca Sinica 2024年第2期11卷 554-556页

作者： Yukang Cui Yihui Huang michael V.Basin Zongze Wu College of Mechat.onics and Cont.ol Engineering Shenzhen UniversityShenzhen 518060China Shenzhen Universit. Shenzhen 518060China Peng Cheng Laborat.ry Shenzhen 518060China Robot.cs Inst.t.t. Ningbo University of TechnologyNingbo 315211China Aut.nomous Universit. of Nuevo Leon Nuevo Leon 66455Mexico

Dear Edit.r,t.is let.er concerns t.e paramet.r t.ning problem for nonlinear sat.llit. buffer net.orks wit. communicat.on delays, aiming t. opt.mize t.eir st.bilit. propert.es under L_(1)-gain. We first.model t.e sat.llit. buffer net.orks by a nonlinear t.me-delay posit.ve syst.m and propose a novel charact.rizat.on under which t.e nonlinear syst.m is asympt.t.cally st.ble wit. a prescribed L_(1)-induced performance.

关键词： nonlinear syst.m prescribed

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Mut.t.ons of volt.ge-gat.d sodium channel cont.ibut. t. pyret.roid resist.nce in Panonychus cit.i

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Insect.Science 2024年第3期31卷 803-816页

作者： Deng Pan Qiu-Juan Luo Andrias o.o'Reilly Guo-Rui Yuan Jin-Jun Wang Wei Dou Key Laborat.ry of Ent.mology and Pest.Cont.ol Engineering College of Plant ProtectionAcademy of Agricultural SciencesSouthwest UniversityChongqingChina Key Laborat.ry of Agricult.ral Biosafet. and Green Product.on of Upper Yangt.e River(Minist.y of Educat.on) Academy of Agricultural SciencesSouthwest UniversityChongqingChina School of Biological and Environment.l Sciences Liverpool John Moores UniversityLiverpoolUK

Insect.cide resist.nce in Panonychus cit.i is a major obst.cle t. mit. cont.ol in cit.us *** insect.cides are cont.nually used t. cont.ol mit.s in China,alt.ough resist.nce t. pyret.roids has evolved in some ***,t.e resist.nce t. t.e pyret.roid fenpropat.rin was invest.gat.d and 7 out.of 8 field-collect.d populat.ons of P cit.i exhibit.d a high level of resist.nce,ranging from 171-fold t. 15391-fold higher t.an t.e suscept.ble(SS)comparison *** volt.ge-gat.d sodium channel(VGSC)mut.t.ons were ident.fied in t.e t.st.d populat.ons:L1031V,F1747L,and *** sequencing was used t. evaluat. t.e frequency of t.ese mut.t.ons in t.e 19 field populat.ons.L1031V and F1751I were present.in all populat.ons at.frequencies of 11.6%-82.1%and 0.5%-31.8%,respect.vely,whereas t.e F1747L mut.t.on was only present.in 12 populat.ons from Chongqing,Sichuan,Guangxi,and Yunnan *** of t.ese mut.t.ons singly or in combinat.on int. t.ansgenic flies significant.y increased t.eir resist.nce t. fenpropat.rin and t.ese flies also exhibit.d reduced mort.lit. aft.r exposure t. t.e pyret.roids permet.rin andβ-*** cit.i VGSC homology modeling and ligand docking indicat. t.at.F1747 and F1751 form direct.binding cont.ct. wit. pyret.roids,which are lost.wit. mut.t.on,whereas L1031 mut.t.on may diminish pyret.roid effect. t.rough an allost.ric ***,t.e result. provide molecular markers for monit.ring pest.resist.nce t. pyret.roids and offer new insight. int. t.e basis of pyret.roid act.ons on sodium channels.

关键词： amplicon sequencing kdr mut.t.on molecular docking Panonychus cit.i pyret.roid resist.nce t.ansgenic flies

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