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Risk factors for hepatocellular carcinoma associated with hepatitis C genotype 3 infection:A systematic review

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World Journal of Gastrointestinal Oncology 2024年第4期16卷 1596-1612页

作者： Hamzah Z Farooq michael james Jane Abbott Patrick Oyibo Pip Divall Naheed Choudhry Graham R Foster Blizard Institute Queen Mary University of LondonLondon E12ATUnited Kingdom School of Health and Psychological Sciences University of LondonLondon EC1V 0HBUnited Kingdom University Hospitals of Leicester Library University Hospitals of Leicester NHS TrustLeicester LE39QPUnited Kingdom

BACKGROUND Hepatitis C virus(HCV)is a blood-borne virus which globally affects around 79 million people and is associated with high morbidity and *** infection leads to cirrhosis in a large proportion of patients and often causes hepatocellular carcinoma(HCC)in people with *** the 6 HCV genotypes(G1-G6),genotype-3 accounts for 17.9%of *** genotype-3 responds least well to directly-acting antivirals and patients with genotype-3 infection are at increased risk of HCC even if they do not have *** To systematically review and critically appraise all risk factors for HCC secondary to HCV-G3 in all ***,we studied possible risk factors for HCC due to HCV-G3 in the literature from 1946 to *** This systematic review aimed to synthesise existing and published studies of risk factors for HCC secondary to HCV genotype-3 and evaluate their strengths and *** searched Web of Science,Medline,EMBASE,and CENTRAL for publications reporting risk factors for HCC due to HCV genotype-3 in all settings,*** Four thousand one hundred and forty-four records were identified from the four databases with 260 records removed as *** thousand eight hundred and eighty-four records were screened with 3514 *** hundred and seventy-one full-texts were assessed for eligibility with seven studies included for *** the seven studies,three studies were retrospective case-control trials,two retrospective cohort studies,one a prospective cohort study and one a cross-sectional study *** were based in hospital settings with four in Pakistan,two in South Korea and one in the United *** total number of participants were 9621 of which 167 developed HCC(1.7%).All seven studies found cirrhosis to be a risk factor for HCC secondary to HCV genotype-3 followed by higher age(five-studies),with two studies each showing male sex,high alpha feto-protein,directly-acting antivirals trea

关键词： Hepatocellular carcinoma Hepatitis C Genotype 3 Systematic review Blood-borne viruses Liver cancer

TCPIP Microsoft certified systems engineer Gary Novosel, Kurt Hudson, james michael Stewart.

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NT server 4 in the enterpriese Microsoft certified systems engineer Ed Tittel, Kurt Hudson, james michael Stewart.

2000年

作者： Gary Novosel Kurt Hudson james michael Stewart.

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Two-dimensional near-infrared photonic crystal fabrication by generation of void channels in solid resin

2000年

作者： Ed Tittel Kurt Hudson james michael Stewart.

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Chinese Optics Letters 2003年第12期1卷 719-721页

作者： michael james Ventura Centre for Micro-Phtonics and the Centre for Ultrahigh-Highwidth Devices for Optical Systems School of Biophysical Sciences and Electrical Engineering Swinburne University of Technology PO Box 218 Hawthorn Victoria 3122 Australia

Two-dimensional (2D) triangular void channel photonic crystals with different lattice constants stacked in two different directions were fabricated by using femtosecond laser micro-explosion in solid polymer material. Fundamental and higher-order stop gaps were observed both in the infrared transmission and reflection spectra. There is an approximately linear relationship between the gap position and the lattice constant. The suppression of the fundamental gap is as high as 70% for 24-layer structures stacked in the T-M direction.

关键词： of as Two-dimensional near-infrared photonic crystal fabrication by generation of void channels in solid resin by that were for with

Achieving Sustainability

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Natural Science 2021年第7期13卷 273-281页

作者： michael james Platts Institute for Manufacturing University of Cambridge Cambridge UK

Although all the symptoms of lack-of-sustainability are physical, the cause is a mindset that needs to be changed. The mindset includes an addictive lock on wanting materialistic solutions to all problems, most of which are not materialistic, but are existential problems about meaningfulness in life. Meaningfulness is an inner understanding about life that is only achieved by insightful reflective thought. This kind of growth is enabled by the right kind of caring leadership that enables people to realise and properly establish their existential relationship with Nature.

关键词： Sustainability Flow of Qi Tree of Life Mindset Conceptual Shift Achievement Motivation Reflective Wisdom Symbiotic Relationships

Strength, Fatigue Strength and Stiffness of High-Tech Bamboo/Epoxy Composites

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Agricultural Sciences 2014年第13期5卷 1281-1290页

作者： michael james Platts Institute for Manufacturing University of Cambridge Cambridge UK

A major problem in the strength data available for cellulose fibre-based materials is that the moisture content of the test specimens is rarely measured, and yet it is the dominant variable in the tests. Detailed strength and stiffness results are presented for Brazilian Dendrocalamus Giganteus bamboo at a wide range of moisture contents down to 2% and the fatigue curve is given for Chinese Moso bamboo at 4% moisture content. Techniques are described for handling the variability of these natural materials, both in design and in manufacturing quality control, for the mass production of large, high-tech composites wind turbine blades.

关键词： Bamboo Moisture Content Epoxy Dry Strength Fatigue Strength Quality Control Composites Manufacturing Process Wind Turbine Blades

Outcomes following minimally invasive dorsal cheilectomy for hallux rigidus:A systematic review

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World Journal of Orthopedics 2024年第6期15卷 585-592页

作者： Katherine Esser james J Butler Mackenzie Roof Nathaniel P Mercer michael C Harrington Alan P Samsonov Andrew J Rosenbaum John G Kennedy Department of Orthopaedic Surgery University of Toledo Medical Center University of Toledo College of Medicine and Life SciencesToledoOH 43614United States Department of Orthopedic Surgery NYU Langone HealthNew YorkNY 10002United States Department of Orthopedic Surgery Albany Medical CenterAlbanyNY 12208United States

BACKGROUND Cheilectomy of the 1^(st)metatarsophalangeal joint(MTPJ)is one of the most common procedures for the management of hallux ***,there is no consensus regarding outcomes following minimally invasive dorsal cheilectomy(MIDC)for the management of hallux *** To evaluate outcomes following MIDC for the management of hallux *** During November 2023,the PubMed,EMBASE and Cochrane Library databases were systematically reviewed to identify clinical studies examining outcomes following MIDC for the management of hallux *** Six studies were *** total,348 patients(370 feet)underwent MIDC for hallux rigidus at a weighted mean follow-up of 37.9±16.5 *** distribution of patients by Coughlin and Shurna's classification was recorded in 4 studies as follows:Ⅰ(58 patients,27.1%),Ⅱ(112 patients,52.3%),Ⅲ(44 patients,20.6%).Three studies performed an additional 1^(st)MTPJ arthroscopy and debridement following *** intra-articular bone debris was observed in 100%of patients in 1 *** weighted mean American orthopedic foot and ankle society score improved from a preoperative score of 68.9±3.2 to a postoperative score of *** complication rate was 8.4%,the most common of which was persistent joint pain and ***-two failures(8.7%)were ***-three secondary procedures(8.9%)were performed at a weighted mean time of 8.6±3.2 months following the index *** This systematic review demonstrated improvements in subjective clinical outcomes together with a moderate complication rate following MIDC for the management of hallux rigidus at short-term follow-up.A moderate reoperation rate at short-term follow-up was *** marked heterogeneity between included studies and paucity of high quality comparative studies limits the generation of any robust conclusions.

关键词： Minimally invasive dorsal cheilectomy Hallux rigidus The first metatarsophalangeal joint Cheilectomy Minimally invasive surgery

The Influence of Extreme Climate Events on Models of Coral Colony Recruitment and Survival in the Caribbean

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American Journal of Climate Change 2012年第1期1卷 33-40页

作者： michael james C. Crabbe Institute of Biomedical and Environmental Science & Technology Faculty of Creative Arts Technologies and Science University of Bedfordshire Luton U.K.

Knowledge of coral recruitment patterns helps us understand how reefs react following major disturbances and provides us with an early warning system for predicting future reef health problems. We have reconstructed and interpreted historical and modern-day recruitment patterns, using growth modeling, in order to understand how hurricanes, storms and bleaching events have influenced coral recruitment in the Caribbean. The results indicate that regional hurricane events negatively impact coral recruitment patterns in the Caribbean, from the south in Tobago to more northerly areas in Belize and Jamaica. However, despite multiple large-scale disturbances, corals are still recruiting to marginal reef systems, and to the Mesoamerican Barrier reef off the coast of Belize. While recruitment and initial growth since the Caribbean-wide bleaching event of 2005 has been successful for Colpophylia natans at the sites studied in North Jamaica, medium and large sized colonies of this species have decreased in numbers since the bleaching event at most sites, except where the rugosity is highest, at Dairy Bull reef.

关键词： Demographics Tropical Storms Hurricanes Cyclones Bleaching Climate Change Global Warming Coral Growth

Coral Reef Populations in the Caribbean: Is There a Case for Better Protection against Climate Change?

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American Journal of Climate Change 2013年第2期2卷 97-105页

作者： michael james C. Crabbe Institute for Biomedical and Environmental Science and Technology Faculty of Creative Arts Technologies and Science University of Bedfordshire Luton UK

Knowledge of factors that are important in coral reef growth help us to understand how reef ecosystems react following major environmental disturbances due to climate change and other anthropogenic effects. This study shows that despite a range of anthropogenic stressors, corals on the fringing reefs south of Kingston harbour, as well as corals on fringing reefs on the north coast of Jamaica near Discovery Bay can survive and grow. Skewness values for Sidastrea siderea and Porites astreoides were positive (0.85 -?1.64) for all sites, implying more small colonies than large colonies. Coral growth rates are part of a demographic approach to monitoring coral reef health in times of climate change, and linear extension rates (***-1) of Acropora palmata branching corals at Dairy Bull, Rio Bueno, and Pear Tree Bottom on the north coast of Jamaica were c. 50 -?90 ***-1 from 2005-2012. The range of small-scale rugosities at the Port Royal cay sites studied was lower than that at the Discovery Bay sites;for example Rio Bueno was 1.05 ± 0.15 and Dairy Bull the most rugose at 2.3 ± 0.16. Diary Bull reef has for several years been the fringing reef with the most coral cover, with a benthic community similar to that of the 1970s. We discuss whether Jamaica can learn from methods used in other Caribbean countries to better protect its coral reefs against climate change. Establishing and maintaining fully-protected marine parks in Jamaica and elsewhere in the Caribbean is one tool to help the future of the fishing industry in developing countries. Developing MPAs as part of an overall climate change policy for a country may be the best way of integrating climate change into MPA planning, management, and evaluation.

关键词： Demographics Belize Jamaica MPAs GDP Hurricanes Fishing Bleaching Climate Change