检索结果-南通市图书馆

Financial instrument pricing using C++ / Daniel j.duffy.

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Update on obesity surgery

2005年

作者： duffy Daniel j.

来源：畅想之星图书光盘版（南... 评论

在线全文

畅想之星图书光盘版（南通市图书馆镜像）

学校读者我要写书评

暂无评论

World journal of Gastroenterology 2006年第20期12卷 3196-3203页

作者： Dan Eisenberg Andrew j.duffy Robert L Bell Department of Surgery Yale University School of Medicine 40 Temple St. Suite 3A New HavenCT 06510United States

The prevalence of obesity in the United States has reached epidemic proportions. With more than 30 million Americans clinically obese, the younger population has also been affected. Surgical therapy should be offered to the severely obese patient who is refractory to nonsurgical therapy, as established by the 1991 NIH Consensus Conference on Gastrointestinal Surgery for Severe Obesity. Surgery is currently the most effective therapy for weight loss. It is far more effective than any other treatment modality, both in terms of the amount of weight loss and in terms of durability in maintaining weight loss.

关键词： Obesity Gastrointestinal surgery Roux-Y gastric bypass

Controversies in the treatment of gastroesophageal reflux and achalasia

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World journal of Gastroenterology 2006年第20期12卷 3155-3161页

作者： Kurt E Roberts Andrew j.duffy Robert L Bell Department of Surgery Yale University School of Medicine 40 Temple St. Suite 3 ANew HavenCT 06510United States

The immense success of laparoscopic surgery as an effective treatment of gastroesophageal reflux disease （GERD） and achalasia has established minimal invasive surgery as the gold standard for these two conditions with lower morbidity and mortality, shorter hospital stay, faster convalescence, and less postoperative pain. One controversy in the treatment of GERD evolves around laparoscopic antireflux surgery （LAP, S） as the preferred treatmerit for Barrett＇s esophagus and the procedure＇s potential to reduce the risk of adenocarcinoma of the esophagus. GERD has also been associated with respiratory symptoms, asthma and laryngeal injury, and a second controversy prompts discussions about whether total or partial fundoplication is the more appropriate treatment for GERD. A new and promising alternative in the treatment of GERD is endoluminal therapy. Three types of this new treatment option will be discussed： radiofrequency energy delivered to the lower esophageal sphincter, the creation of a mechanical barrier at the gastroesophageal junction, and the direct endoscopic tightening of the lower esophageal sphincter. Laparoscopic surgery is discussed not only as a very effective treatment for GERD but also as permanent cure for achalasia. This review analyzes the three most important treatment options for achalasia： medications, pneumatic dilatation, and surgical therapy. Medications as the only true non-invasive option in the treatment of achalasia are not as effective as LAPS because of their short half-life and variable absorption due to the poor esophageal emptying. The second treatment option, pneumatic dilatation, involves the stretching of the lower esophagus and is still considered the most effective nonsurgical treatment for achalasia. Finally, surgical therapy for achalasia and the two major controversies concerning this laparoscopic treatment are discussed. The first involves the extent to which the myotomy is extended onto the stomach, and the second concer

关键词： Gastroesophageal reflux disease Nissen Toupet Fundoplication Achalasia Heller myotomy

Evolution of surgical skills training

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World journal of Gastroenterology 2006年第20期12卷 3219-3224页

作者： Kurt E Roberts Robert L Bell Andrew j.duffy Department of Surgery Yale University School of Medicine 40 Temple StreetSuite 3ANew HavenCT 06510United Staets

Surgical training is changing： one hundred years of tradition is being challenged by legal and ethical concerns for patient safety, work hours restrictions, the cost of operating room time, and complications. Surgical simulation and skills training offers an opportunity to teach and practice advanced skills outside of the operating room environment before attempting them on living patients. Simulation training can be as straight forward as using real instruments and video equipment to manipulate simulated ＂tissue＂ in a box trainer. More advanced, virtual reality simulators are now available and ready for widespread use. Early systems have demonstrated their effectiveness and discriminative ability. Newer systems enable the development of comprehensive curricula and full procedural simulations. The Accreditation Council of Graduate Medical Education＇s （ACGME） has mandated the development of novel methods of training and evaluation. Surgical organizations are calling for methods to ensure the maintenance of skills, advance surgical training, and to credential surgeons as technically competent. Simulators in their current form have been demonstrated to improve the operating room performance of surgical residents. Development of standardized training curricula remains an urgent and important agenda, particularly for minimal invasive surgery. An innovative and progressive approach, borrowing experiences from the field of aviation, can provide the foundation for the next century of surgical training, ensuring the quality of the product. As the technology develops, the way we practice will continue to evolve, to the benefit of physicians and patients.

关键词： Surgery Training Certification Skills Simulation Curriculum

Choledocholithiasis: Evolving standards for diagnosis and management

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World journal of Gastroenterology 2006年第20期12卷 3162-3167页

作者： Marilee L Freitas Robert L Bell Andrew j.duffy Department of Surgery Yale University School of Medicine 40 Temple StreetSuite 3 ANew HavenCT 06510United States

Cholelithiasis, one of the most common medical conditions leading to surgical intervention, affects approximately 10 % of the adult population in the United States. Choledocholithiasis develops in about 10%-20% of patients with gallbladder stones and the literature suggests that at least 3%-10% of patients undergoing cholecystectomy will have common bile duct （CBD） stones. CBD stones may be discovered preoperatively, intraoperatively or postoperatively Multiple modalities are available for assessing patients for choledocholithiasis including laboratory tests, ultrasound, computed tomography scans （CT）, and magnetic resonance cholangiopancreatography （MRCP）. Intraoperative cholangiography during cholecystectomy can be used routinely or selectively to diagnose CBD stones. The most common intervention for CBD stones is ERCP. Other commonly used interventions include intraoperative bile duct exploration, either laparoscopic or open. Percutaneous, transhepatic stone removal other novel techniques of biliary clearance have been devised. The availability, of equipment and skilled practitioners who are facile with these techniques varies among institutions. The timing of the intervention is olden dictated by the clinical situation.

关键词： Choledocholithiasis Laparoscopy Diagnosis Treatment Cholangiogram

Biomarkers of Aging: Changes in Circadian Rhythms Related to the Modulation of Metabolic Output

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Biomedical and Environmental Sciences 1991年第1期4卷 182-191页

作者： PETER H.duffy RITCHIE j.FEUERS Food and Drug Administration Natiomd Center Jbr Toxicological Research JeffersonFood and Drug Administration Natiomd Center Jbr Toxicological Research Jefferson Arkansas 72079 To whom correspondence should be addressedArkansas 72079

Twenty-four hour (circadian) rhythmicity is an important component of biological variability associated with studies relating to biomarkers of aging. Chronobiological testing techniques must be utilized because (1) many variables that are related to the modulation of metabolic output vary dramatically at different times of the day; (2) various experimental variable and treatment groups must be synchronized with environmental cues that control circadian rhythms; and (3) multiple circadian variables may interact together to modulate the rate of aging. The rhythm for physiological factors such as whole animal metabolic output, body temperature, heart rate, urine flow, potassium, etc. were found to be dissociated or altered by the senescence process; behavioral variables such as spontaneous activity, wheel running, feeding and drinking, verbal performance, as well as sleep-wakefulness rhythms, seem to be accurate predictors of biological age. Circadian rhythms for a variety of enzymes of intermediary metabolism which are directly associated with energy metabolism have been well documented. These well-defined rhythms of enzyme activity have also been shown to degenerate with aging. Rhythms tend to lose amplitude as activity falls with age and as a general loss of regulation (especially time of day where maximal activity might be found) of activity across the 24-h span occurs. As with behavioral variables, changes in enzyme rhythms appear to accurately predict aging. Generally speaking, the loss of temporal organization with age, characterized by decreased circadian amplitude, loose internal synchronization, and poor response to external environmental time queues, is associated with poor health states and decreased longevity. Temporal rhythms for whole animal parameters are highly correlated with molecular events, such as regulation of cellular metabolism. DNA repair, and gene expression. Automated data acquisition and process control systems will be required for future C

关键词： Biomarkers of Aging Changes in Circadian Rhythms Related to the Modulation of Metabolic Output

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

双折射涂层厚度效应的实验研究

力学季刊 1965年第2期 57-62页

作者： j.duffy C.Mylonas 杨槐堂

本文提出了双折射涂层性能的一个实验研究结果,当载荷作用时,金属表面出现急烈的应变梯度和曲率变化的情况下,提供了一个表面应变的精确测量。这些实验是按照一个早已提出的理论分析进行的,对于任何厚度的涂层,如果表面应变为一维时,该... 详细信息

本文提出了双折射涂层性能的一个实验研究结果,当载荷作用时,金属表面出现急烈的应变梯度和曲率变化的情况下,提供了一个表面应变的精确测量。这些实验是按照一个早已提出的理论分析进行的,对于任何厚度的涂层,如果表面应变为一维时,该理论分析给出了预计条纹级数的一个方法。实验结果表明,当对涂层的厚度作出适当的修正或者涂层足够薄时,双折射涂层能够精确地用于测量表面应变。然而,对于具体问题,什么是'足够薄',只有对某些特有条件的研究才能确定,这些条件包括应变梯度的陡度(steepness of the strain gradients),表面应变的变化以及所要求的精度。

关键词：分界面应变梯度厚度效应杆件涂层曲率金属表面双折射材料平均应变应变差

A mathematical model for the dynamics and control of malaria in Nigeria

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Infectious Disease Modelling 2022年第4期7卷 728-741页

作者： O.C.Collins K.j.duffy Institute of Systems Science Durban University of TechnologyDurban4000South Africa

Malaria is a life-threatening disease endemic in many African countries especially Nigeria.A mathematical model is used to study the dynamics of malaria in *** model incorporates drug resistance,treatment,and the use of mosquito nets as preventive *** fitting the model to data on the incidence of malaria in Nigeria,important parameters associated with the disease dynamics are *** these estimated parameters,the basic reproduction number is calculated,future dynamics simulated,and those parameters with a large impact on Nigerian malaria ***,the results indicate that the disease is likely to remain endemic in Nigeria unless better control measures are focused on the dominant resistant strain,treatment is improved and the use of mosquito nets become widespread.

关键词： Malaria dynamics Stability analyses Basic reproduction number Model fitting Sensitivity analysis

Biomarkers of Aging: Changes in Circadian Rhythms Related to the Modulation of Metabolic Output

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Biomedical and Environmental Sciences 1991年第Z1期 182-191页

作者： PETER H.duffy,RITCHIE j.FEUERS Food and Drug Administration Natiomd Center jbr Toxicological Research jefferson Food and Drug Administration Natiomd Center jbr Toxicological Research jefferson Arkansas 72079 To whom correspondence should be addressed Arkansas 72079

关键词： Biomarkers of Aging Changes in Circadian Rhythms Related to the Modulation of Metabolic Output