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Where is the policy?A bibliometric analysis of the state of policy research on medical tourism

Global Health Research and Policy 2020年第1期5卷 252-267页

作者： Altaf Virani Adam M.Wellstead michael howlett Lee Kuan Yew School of Public Policy National University of Singapore469C Bukit Timah RoadSingapore 259772Singapore Department of Social Sciences Michigan Technological UniversityHoughtonUSA Department of Political Science Simon Fraser UniversityBurnabyBritish ColumbiaCanada

Background:It is imperative that researchers studying medical tourism connect their work with policy,so that its real-world challenges can be better understood,and more effectively *** article gauges the scope and evolution of policy thinking in medical tourism research through a bibliometric review of published academic literature,to establish the extent to which researchers apply public policy theories and frameworks in their investigation of medical tourism,or consider the policy imperatives of their ***:A Boolean search of the Web of Science(WoS)Core Collection was performed to identify policy-related publications on medical *** analyzed the results using bibliometrics and a data visualization software called VOSviewer to identify patterns in knowledge production and underlying network linkages in policy research on the ***:Our findings suggest that only a small proportion of medical tourism research explicitly addresses policy issues or applies policy paradigms in their study ***-specialized journals serving practitioners publish less research as compared to interdisciplinary social and health policy ***,there are significant geographical and disciplinary disparities in the policy-orientation of research,and a predilection towards select policy areas such as reproductive and transplant tourism to the neglect of more holistic governance and health system ***:This article is a call to action for greater engagement by policy scholars on medical tourism,and for health researchers to more explicitly consider how their research might contribute to the understanding and resolution of contemporary policy challenges of medical *** to clearly and consistently make the policy connection is a lost opportunity for researchers to frame the public debate,and influence policy thinking on medical tourism.

关键词： Medical tourism Health tourism Healthcare tourism Policy research Policy thinking Bibliometric analysis

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Apolipoproteins and amyloid fibril formation in atherosclerosis

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Protein & Cell 2011年第2期2卷 116-127页

作者： Chai Lean Teoh michael D.W.Griffin Geoffrey J.howlett Department of Biochemistry and Molecular Biology University of MelbourneParkvilleVictoria 3010Australia Bio21 Molecular Science and Biotechnology InstituteUniversity of MelbourneParkvilleVictoria 3010Australia

Amyloid fibrils arise from the aggregation of misfolded proteins into highly-ordered *** accumulation of these fibrils along with some non-fibrillar constituents within amyloid plaques is associated with the pathogenesis of several human degenerative diseases.A number of plasma apolipoproteins,including apolipoprotein(apo)A-I,apoA-II,apoC-II and apoE are implicated in amyloid formation or influence amyloid formation by other *** review present knowledge of amyloid formation by apolipoproteins in disease,with particular focus on *** insights into the molecular mechanisms underlying their amyloidogenic propensity are obtained from in vitro studies which describe factors affecting apolipoprotein amyloid fibril formation and ***,we outline the evidence that amyloid fibril formation by apolipoproteins might play a role in the development and progression of atherosclerosis,and highlight possible molecular mechanisms that could contribute to the pathogenesis of this disease.

关键词： misfolding apolipoproteins amyloid fibril atherosclerosis

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Influence of food availability,plant productivity,and indigenous forest use on ranging behavior of the endangered samango monkey(Cercopithecus albogularis schwarzi),in the Soutpansberg Mountains,South Africa

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Integrative Zoology 2020年第5期15卷 385-400页

作者： Edwin J.PARKER Russell A.HIL Andrew T.L.ALLAN Caroline howlett Nicola F.KOYAMA School of Natural Sciences and Psychology Liverpool John Moores UniversityLiverpoolUK Primate and Predator Project Lajuma Research CentreLouis TrichardtSouth Africa Department of Anthropology Durham UniversityDurhamUK Department of Zoology University of VendaThohoyandouSouth Africa School of Anthropology and Conservation University of KentKentUK

Understanding the determinants of ranging patterns in species susceptible to habitat fragmentation is fundamental for assessing their long-term adaptability to an increasingly human-dominated *** aim of this study was to determine and compare the influence of ground-based food availability,remotely sensed plant productivity,and indigenous forest use on the ranging patterns of the endangered samango monkey(Cercopithecus albogularis schwarzi).We collected monthly ranging data on two habituated samango monkey groups,from February 2012 to December 2016,from our field site in the Soutpansberg Mountains,South *** used linear mixed models to explore how food availability,plant productivity,and indigenous forest use influenced monthly ranging patterns,while controlling for group size,number of sample days and day *** found that as more areas of high plant productivity(derived from remotely sensed EVI)were incorporated into the ranging area,both total and core monthly ranging areas *** addition,both total ranging area and mean monthly daily path length decreased as more indigenous forest was incorporated into the ranging ***,we found no effect of either ground-based food availability or remotely sensed plant productivity on ranging *** findings demonstrate the behavioral flexibility in samango monkey ranging,as samangos can utilize matrix habitat during periods of low productivity but are ultimately dependent on access to indigenous forest *** addition,we highlight the potential of using remotely sensed areas of high plant productivity to predict ranging patterns in a small ranging,forest-dwelling guenon,over ground-based estimates of food availability.

关键词： food availability forest use plant productivity ranging patterns remote sensing samango monkey

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Opportunistic infection of Aspergillus and bacteria in captive Cape vultures (Gyps coprotheres)

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Asian Pacific Journal of Tropical Biomedicine 2013年第5期3卷 401-406页

作者： Stephen Chege Judith howlett Majid Al Qassimi Arshad Toosy Joerg Kinne Vincent Obanda Life Sciences Department Al Ain Wildlife Park and Resort Central Veterinary Research Laboratories Veterinary Services Department Kenya Wildlife Service

Objective:To describe clinical signs,pathology,diagnosis and treatment of Cape vultures in which Aspergillus fumigatus(***)and mixed species of bacteria were ***:Six Cape vultures sourced from South Africa for exhibition at Al Ain Zoo developed illness manifesting as anorexia,dyspnea,polyuria and *** vultures died manifesting"pneumonia-like syndrome".These three vultures were necropsied and gross lesions recorded,while organ tissues were collected for *** organs were swabbed for bacteriology and *** live vultures,blood was collected for hematology and biochemistry,oropharyngeal and cloacal swabs were collected for mycology and ***:*** was isolated from the three dead vultures and two live ones that eventually *** of the dead vulture and two live vultures were co-infected with *** and mixed species of bacteria that included Clostridium perfringens,Pseudomonas,Staphylococcus,Escherichia,Proteus,Enterococcus and *** of the Cape vulture and a Lappetfaced vulture,however,were free of Aspergillus or bacterial *** necropsy,intestinal hemorrhages were observed and the lungs were overtly congested with granulomas present on caudal air *** examinations demonstrated granulomatous lesions that were infiltrated by mononuclear cells and giant ***:Aspergillosis is a persistent threat to captive birds and we recommend routine health assessments so that early diagnosis may prompt early *** is likely that prompt prophylaxis by broad spectrum antibiotics and antifungals medication contributed to the survival of some of the vultures.

关键词： Aspergillosis Cape vultures Wild birds Aspergillus Bacteria

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Maturation of Osteoblast-Like Saos-2 on Hydroxyapatite Ceramics

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High Technology Letters 2004年第2期10卷 46-50页

作者：王朝元 Duan Yourong Boban Markovic James Barbara C.Rolfe howlett Zhang Xingdong Hala Zreiqat Engineering Research Center in Biomaterials Sichuan University Chengdu 610064 P.R.China Yangtze Fisheries Institute Chinese Academy of Fishery Science Jingzhou 434000 P.R.China Engineering Research Center in Biomaterials Sichuan University Chengdu 610064 P.R.China Chemical Safety and Toxicology Laboratories School of Safety Science UNSW 2052 NSW Sydney Australia Bone Biomaterial Unit Department of Pathology UNSW 2052 NSW Sydney Australia

Hydroxyapatite ceramics (HA) has been proved to be excellent in biocompatibility and bioactivity. However, limited information is available concerning how HA ceramics affects the maturation of osteoblasts in molecular biological level in vitro. This study examines the mRNA expression and protein production of bone-related genes in osteoblast-like cell line (Saos-2) cultured on HA disks. Saos-2 cells are seeded onto the substrates and cultured for 18 days. Harvested cells are tested for the cell growth rate, expression of mRNAs for osteocalcin and alkaline phosphatase, and protein production of bone sialoprotein and osteocalcin. MTS assay shows that cell proliferates well on HA ceramic substrate. After 9d, bone sialoprotein and osteocalcin protein production in SaPS-2 increases more on HA surfaces than on control material. As bone sialoprotein and osteocalcin are the genes to be highly expressed at the late stage of osteoblast differentiation, this study reveals that after long time culture in HA, HA can induce Saos-2 maturation. The behavior of Saos-2 on HA surfaces revealed in this study provides valuable information for the understanding of the biocompatibility and bioactivity of HA ceramics.

关键词：羟磷灰石制陶业细胞增殖相关骨基因表达熟化 Saos-2 分子生物学

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Conversion coatings of Mg-alloy AZ91D using trihexyl(tetradecyl) phosphonium bis(trifluoromethanesulfonyl)amide ionic liquid

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Science China Chemistry 2012年第8期55卷 1598-1607页

作者： howlett P. C. GRAMET S. LIN J. EFTHIMIADIS J. CHEN X. B. BIRBILIS N. FORSYTH M. ARC Centre of Excellence for Electromaterials Science Institute for Frontier Materials Deakin Univerxlty Burwood Campus Burwood Victoria 3125 Australia CAST Cooperative Research Centre Department of Materials Engineering Monash University Melbourne Victoria 3800 Australia

This work reveals the performance of a trihexyl(tetradecyl)phosphonium bis(trifluoromethanesulfonyl)amide ([P6,6,6,14][NTf2]) ionic liquid (IL) conversion coating upon AZ91D. Such conversion coatings represent a novel avenue for chromate replacement. An optimization of coating performance was pursued by careful alloy pretreatment to generate a surface on which the coating performs best, as the AZ91 substrate is distinctly different from pure or dilute Mg alloys. The results reveal that a functional conversion coating can be achieved, retarding anodic dissolution kinetics, causing a significant decrease in corrosion rate. The coating efficacy is closely tied to the pretreatment performed, which dictates both the microstructural and electrochemical heterogeneity of the surface. The resulting coatings were found to contain MgxFx and phosphonium cation related components, the proportions of which were dependent on the pretreatment.

关键词： AZ91D corrosion conversion coating ionic liquid pretreatment

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Increasing Employees’ Fruit Consumption through Access and Peer Support at Work

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Food and Nutrition Sciences 2013年第10期4卷 88-95页

作者： Amanda D. Hutchinson Georgina howlett Carlene Wilson Flinders Centre for Innovation in Cancer Flinders University Adelaide Australia Cancer Council South Australia Adelaide Aus- tralia School of Psychology Flinders University Adelaide Australia.

Objective: To assess the effect of providing free fruit and peer support in the workplace, on employees’ consumption of fruits and high fat snacks at work and home. Methods: Three worksites, including 75 employees, were randomly assigned to a free fruit condition (Group A), a free fruit and peer education and modelling condition (Group B), and a control group (Group C). Groups A and B had free fruit delivered to their workplace each morning for four weeks. Consumption of fruit and high fat snacks was measured pre- and post-intervention, and after a two week maintenance period. Results: Despite a small sample, the intervention increased employees’ fruit intake at work, decreased high fat snacks and was more successful in those who were not currently meeting the recommendations of two pieces of fruit per day. Peer support led to increased fruit consumption at work and sustained decreases in unhealthy snacks post-intervention. Conclusions: The provision of fruit in the workplace with peer support is a simple and effective method for improving fruit consumption at work in the short-term, particularly in those not meeting current recommendations. In addition, those participating in the intervention reduced their consumption of high fat snacks. Further research is necessary to determine whether a longer larger scale intervention can sustain dietary changes and thereby reduce risk for chronic disease in the Australian population.

关键词： Workplace Peer Education Health Promotion Fruit

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Haematology and biochemistry values of captive sand cats(Felis margarita)in Al Ain Wildlife Park and Resort,United Arab Emirates

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Journal of Coastal Life Medicine 2013年第2期 141-144页

作者： Stephen Chege Arshad Toosy Judith howlett Ahmed Saker John Kagira Al Ain Wildlife Park and Resort Life Sciences DepartmentVeterinary Section PO Box 1204Al AinUAE Jomo Kenyatta University of Agriculture and Technology PO Box 62000-00200NairobiKenya

Objective:To investigate the haematology and biochemistry values of apparently healthy captive sand cats kept in Al Ain Wildlife Park and Resort,United Arab Emirates,with a view to establishing baseline ***:Blood was collected from the femoral vein using aseptic techniques,kept in a cool box and sent to laboratory for *** blood was analysed for haematological and biochemical values using veterinary hematology and chemistry analysers(ABX ABC Vet,Horiba ABX SAS^(®)Montpellier,France).Results:Haematological values were within the normal ranges recorded in domestic cats and there was no statistical difference between values found in males and *** aminotransferase values were higher(P0.05)between males and females ***:Our results present reference ranges for haematology and biochemistry parameters in captive sand *** values will be important for diagnosis of various diseases and monitoring of treatments.

关键词： Al Ain Wildlife Park and Resort Apparently healthy Biochemistry Haematology Sand cats

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年龄对心血管系统的影响(英文)

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中国心血管杂志 2011年第1期16卷 69-78页

作者： SusanE.howlett 王凡 Departments of Pharmacology and Medicine Division of Geriatric MedicineDalhousie UniversityHalifaxCanada

高龄是发生心血管疾病的一个重要危险因素。很显然,随着老年人吸烟,以及患高血压、糖尿病、血脂异常等儿率的增加,更容易发生心血管疾病。另外有证据显示,即使无其他危险因素,衰老也会引起心血管结构和功能的变化。研究表明,随着时间的... 详细信息

高龄是发生心血管疾病的一个重要危险因素。很显然,随着老年人吸烟,以及患高血压、糖尿病、血脂异常等儿率的增加,更容易发生心血管疾病。另外有证据显示,即使无其他危险因素,衰老也会引起心血管结构和功能的变化。研究表明,随着时间的推移,衰老的心脏和血管出现了细胞和亚细胞缺陷,更重要的是,即使无明显心血管疾病的人也存在与年龄相关的这些变化,使老年人易患心血管疾病,引起舒张功能障碍和单纯收缩性高血压等常见问题。

关键词：年龄因素心血管系统肌细胞心脏高血压

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IT需要为飓风做的准备：在飓风威胁时IT要做的10件事

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Windows IT Pro Magazine（国际中文版） 2008年第12期 52-52,55页

作者： Tony howlett 肖欣(译)

假设我们在海岸边上，现在处于飓风到达前的混乱局面中，把以下几件事打印出来似乎比较好，考虑清楚在飓风逼近时你要做的一些；隹备工作。当然，在为其它一些有提前预警的灾难进行准备时，也会用到这些事项中的一部分，例如暴风雪、逼... 详细信息

假设我们在海岸边上，现在处于飓风到达前的混乱局面中，把以下几件事打印出来似乎比较好，考虑清楚在飓风逼近时你要做的一些；隹备工作。当然，在为其它一些有提前预警的灾难进行准备时，也会用到这些事项中的一部分，例如暴风雪、逼近的森林火灾（例如在加里福尼亚，不是建筑物火灾）。我这里可能遗漏了一些事项，大家可以指出来，我会把它们加到列表中。同时我要离开做一些准备了。祝我们在德克萨斯海湾航行的小伙子们好运吧!大西洋彼岸再见!

关键词：飓风 IT 威胁建筑物火灾森林火灾德克萨斯暴风雪大西洋

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