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Restless legs syndrome is contributing to fatigue and low quality of life levels in hemodialysis patients

World Journal of Nephrology 2017年第5期6卷 236-242页

作者： Christoforos D Giannaki michael hadjigavriel Akis Lazarou Aristos michael Loukas Damianou Efthimios Atmatzidis Ioannis Stefanidis Georgios M Hadjigeorgiou Giorgos K Sakkas Marios Pantzaris Department of Life and Health Sciences University of NicosiaNicosia CY 1700Cyprus the Cyprus Institute of Neurology and Genetics Nicosia CY 1683Cyprus Hemodialysis Unit Larnaca General HospitalLarnaca CY 6021Cyprus Hemodialysis Unit Limassol General HospitalLimassol CY 3304Cyprus School of Medicine University of Thessaly41110 LarisaGreece Faculty of Sport and Health Sciences University of St Mark and St JohnPlymouth PL6 8BHUnited Kingdom

AIM To examine whether hemodialysis(HD) patients with restless legs syndrome(RLS) are subjects of greater fatigue and impaired quality of life(QoL) compared to HD patients without *** Eighty five stable HD patients participated in this study. According to their RLS status, the patients were dividedinto the RLS group(n = 23) and the non-RLS group(n = 62). QoL, fatigue, sleep quality, daily sleepiness and depression symptoms were assessed by using various questionnaires. Finally, biochemical parameters including iron, ferritin, hemoglobin, hematocrit and parathormone were assessed. RESULTS The HD patients with RLS scored worse in all the questionnaires used in the study(P < 0.05). The patients with RLS were more likely to receive the HD therapy on the morning shift, whilst 43.5% of the RLS patients reported to experience the RLS symptoms also during HD. The severity of RLS was correlated with fatigue, depression score and sleep quality(P < 0.05). CONCLUSION HD patients with RLS are subject to lower QoL related parameters and greater fatigue compared to HD patients without RLS. RLS should be successfully managed in order to improve the QoL of the sufferers.

关键词： Sleep quality Depression Secondary restless legs syndrome Fatigue Quality of life

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