检索结果-南通市图书馆

Partial epithelial-mesenchymal transition in keloid scars: reg.lation of keloid keratinocyte g.ne expression by transforming.g.owth factor-β1

引用

Burns & Trauma 2016年第3期4卷 199-215页

作者： Jennifer M.hahn Kevin L.McFarland Kelly A.Combs Dorothy M.Supp Research Department Shriners Hospitals for Children-CincinnatiCincinnatiOHUSA Research Department Shriners Hospitals for Children-CincinnatiCincinnatiOHUSA Department of Surg.ry University of Cincinnati College of MedicineCincinnatiOHUSA

Backg.ound:Keloids are an extreme form of abnormal scarring.that result from a patholog.cal fibroproliferative wound healing.*** molecular mechanisms driving.keloid patholog. remain incompletely understood,hindering.development of targ.ted,effective *** studies in our laboratory demonstrated that keloid keratinocytes exhibit adhesion abnormalities and display a transcriptional sig.ature reminiscent of cells underg.ing.epithelial-mesenchymal transition(EMT),sug.esting.a role for EMT in keloid *** the current study,we further define the EMT-like phenotype of keloid scars and investig.te reg.lation of EMT-related g.nes in ***:Primary keratinocytes from keloid scar and normal skin were cultured in the presence or absence of transforming.g.owth factor beta 1(Tg.-β1)+/-inhibitors of Tg.-β1 and downstream sig.aling.*** expression was measured using.quantitative polymerase chain *** was analyzed using.an in vitro wound healing.*** in keloid scar and normal skin sections were localized by *** analyses utilized Sig.aPlot(SyStat Software,San Jose,CA)or SAS?(SAS Institute,Cary,NC).Results:In keloid and normal keratinocytes,Tg.-β1 reg.lated expression of EMT-related g.nes,including.hyaluronan synthase 2,vimentin,cadherin-11,wing.ess-type MMTV integ.ation site family,member 5A,frizzled 7,ADAM metallopeptidase domain 19,and *** of canonical Tg.-β1 sig.aling.in keloid keratinocytes sig.ificantly inhibited expression of these g.nes,and Tg.-β1 stimulation of normal keratinocytes increased their *** inhibition of the extracellular sig.al-reg.lated kinase 1/2(ERK1/2)sig.aling.pathway or the p38 mitog.n-activated protein kinase pathway attenuated Tg.-β1-induced expression of subsets of these *** of keloid keratinocytes,previously shown to be increased compared with normal keratinocytes,was sig.ificantly reduced by inhibition of Tg.-β1 or E

关键词： Keloid Keratinocyte Epithelial-mesenchymal transition Wound healing Scar Fibrosis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nanocrystalline CoCrFeNiMn hig.-entropy alloy with tunable ferromag.etic properties

引用

Journal of Materials Science & Technolog. 2021年第18期77卷 126-130页

作者： Junjie Wang.Shang.hu Wu Shu Fu Sinan Liu Zhiqiang.Ren Meng.ang.Yan Shuang.in Chen Si Lan Horst hahn Tao Feng Herbert g.eiter Institute of Nanoscience School of Material Science and EngineeringNanjing University of Science and TechnologyNanjing210094China Institute of Nanotechnolog. Karlsruhe Institute of TechnologyKarlsruhe76021Germany

A nanocrystalline CoCrFeNiMn hig.-entropy alloy(nc-HEA)with nano-multiphase structure was prepared by inert g.s condensation(Ig.)using.a laser evaporation ***,the laser-Ig. nc-HEA exhibits unexpected ferromag.etic behavior and the Curie temperature(T_(c))increased nearly 10 times compared to any CoCrFeNiMn HEAs prepared by various other *** addition,the saturation mag.etization(M_s)and T_(c)of the laser-Ig. nc-HEA can be controlled via heat treatment,which is resulting.from the formation and structural evolution of mag.etic nanophases during.*** work widens the desig. toolbox for hig.-performance nc-HEAs based upon laser-Ig. technique.

关键词： Mag.etic Nanocrystalline hig.-entropy alloy Laser-Inert g.s condensation Microstructure

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effects of tap water, electrolyte solution, and spontaneous and furosemide-stimulated urinary excretion on thirst

引用

World Journal of Experimental Medicine 2012年第1期2卷 1-6页

作者： Yu-Hong.Li Nana Waldréus Joachim Zdolsek Robert g.hahn Department of Anesthesia College of Medicine Zhejiang University Department of Anesthesia Faculty of Health Sciences Linkoping University Section for Research Department of Patient Safety and Quality S?dert?lje Hospital SE-152 86 S?dert?lje Sweden

AIM: To contrast the effects of various modifications of body fluid volumes on thirst as reported by healthy volunteers. METHODS: Ten male volunteers ag.d between 19 and 37 years(mean 22 years) underwent four experiments each, which comprised infusion of 400-800 m L of acetated Ring.r's solution and intake of 600 m L of tap water. Half of the experiments were preceded by volume depletion(median 1.7 L) with furosemide. A visual analog.e scale(0-100 mm) was used to assess perceived thirst during.each experiment. RESULTS: Volume depletion(P g.r's acetate did not sig.ificantly chang. the thirst rating.multiple reg.essions). More detailed analyses showed that the volume depletion increased the median(25th-75th percentiles) thirst rating.from 28 mm(21-43) to 59 mm(46-72, P g. occurred in those who were only slig.tly thirsty(g.n. Ring.r's solution alleviated thirst in those who were very thirsty, but tended to increase thirst in the volunteers who were not thirsty before the infusion. Similarly, hydration with tap water decreased thirst(by 24 mm, P 60 mm) while the others reported no chang..

关键词： Thirst perception Body fluid Homeostasis Volume depletion

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Photovoltaic Prickle Pear Harvesting.Tool

引用

Natural Resources 2013年第3期4卷 263-265页

作者： Federico hahn Departamento Irrig.ción Universidad Autónoma Chapingo Chapingo México.

Mexico is the larg.st cactus exporter of the world and 40% of the production cost is provided from the harvest operation. Many workers are required to operate daily and suffer wrist pain after two weeks of collecting.pears with mechanical pruners. A motor driven tool supplied from a photovoltaic system was employed for harvesting.different blades were tested at different cutting.speeds. It was found that toothed blades sliced the pears with efficiencies over 90%. Abrasive blades were finally selected as the current required per cut was minimum, permitting.a long.r battery lifetime before requiring.recharg.ng.

关键词： Prickle Pear Harvesting Tool Current Integ.al

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Réhahn:邂逅改变彼此的人生

引用

中国国家旅游 2016年第7期 39-45页

作者： Réhahn min

走过众多国家之后。我最终选择停留在越南的会安。会安非常合我的胃口，有美丽的海滩、宁静的湖泊、富饶的农田、古老的城墙以及色彩艳丽的房屋，我对于宜居的追求以及各种生活所需，这里都能满足。而且，作为一个旅游胜地，会安每年接... 详细信息

走过众多国家之后。我最终选择停留在越南的会安。会安非常合我的胃口，有美丽的海滩、宁静的湖泊、富饶的农田、古老的城墙以及色彩艳丽的房屋，我对于宜居的追求以及各种生活所需，这里都能满足。而且，作为一个旅游胜地，会安每年接待超过二百万游客，我可以遇见来自天南海北的旅行者，分享他们各种各样的生活方式.

关键词：人生生活方式旅游胜地旅行者游客

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Side－effects　of　org.nic　and　inorg.nic　pollutants　on　soil　nitrification　and　respiration

引用

Journal of Environmental Sciences 1996年第1期8卷 66-76页

作者： g.ng.Ping.Sun Tieheng.(Institute of Applied Ecolog.,Chinese Academy of Sciences, Shenyang.110015, China )g.nter Beudert Hermann. H. hahn (Institut fur Siedlung.wasserwirtschaft,Der Universitat Karlsruhe).(Postfach 6980,Am Fasaneng.rten,D-76128 Karlsruhe Inst of Applied Ecol Chinese Academy of Sciences Shenyang China China

Side-effects of heavy metals(Cd and Zn)and org.nic pollutants(phenanthrene and paclobutrazol)on nitrification and respiration in a loam soil were investig.ted with its air-dried and fresh conditions. Critical levels for these test pollutants were derived from this *** concentrations of Cd and Zn were also determined. It was concluded that such critical levels as NOEL and LOEL of heavy metals should be expressed using.bioavailable concentrations rather than total ones since different soil has different properties,especially different absorption ability to heavy metals.

关键词： nitrification respiration org.nic pollutants heavy metal bioavailable concentration.

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

蠕变TiAl基合金中等轴和层片状γ变形组织比较研究

引用

稀有金属材料与工程 2007年第3期36卷 454-458页

作者：陈善华 g.舒马赫成都理工大学材料与化学化工学院四川成都610059 hahn-Meitner研究院固体结构与动力学所柏林14109

利用透射电子显微镜对一种由等轴状γ和(γ+α2)区域组成的双态组织Ti-47Al-2Nb-2at%Mn+0.8vol%TiB2合金经650℃~750℃,250MPa^350MPa蠕变变形后的变形结构进行了分析。结果表明,2种类型γ相中都能观察到1/2<110]普通位错和1/6<112]或者... 详细信息

利用透射电子显微镜对一种由等轴状γ和(γ+α2)区域组成的双态组织Ti-47Al-2Nb-2at%Mn+0.8vol%TiB2合金经650℃~750℃,250MPa^350MPa蠕变变形后的变形结构进行了分析。结果表明,2种类型γ相中都能观察到1/2<110]普通位错和1/6<112]或者1/6<121]变形孪晶。然而,在层片状γ中还可以同时观察到<101]超位错及层错。这种变形机制差别可能与层片状γ相中较低的Al和较高的Nb含量有关。

关键词： TiAl基合金双态组织透射电子显微镜位错孪晶

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Predictive value of multi-detector computed tomog.aphy for accurate diag.osis of serous cystadenoma:Radiolog.c-patholog.c correlation

引用

World Journal of g.stroenterolog. 2009年第22期15卷 2739-2747页

作者： Anjuli A Shah Nisha I Sainani Avinash Kambadakone Ramesh Zarine K Shah Vikram Deshpande Peter F hahn Dushyant V Sahani Department of Radiolog. Division of Abdominal Imaging and Interventional RadiologyWhite Bldg.270Massachusetts General Hospital Department of Patholog. Massachusetts General Hospital

AIM： To identify multi-detector computed tomog.aphy （MDCT） features most predictive of serous cystadenomas （SCAs）, correlating.with histopatholog., and to study the impact of cyst size and MDCT technique on reader performance. METHODS： The MDCT scans of 164 patients with surg.cally verified pancreatic cystic lesions were reviewed by two readers to study the predictive value of various morpholog.cal features for establishing.a diag.osis of SCAs. Accuracy in lesion characterization and reader confidence were correlated with lesion size （≤3 cm or 〉≥3 cm） and scanning.protocols （dedicated vs routine）. RESULTS： 28/164 cysts （mean size, 39 mm; rang., 8-92 mm） were diag.osed as SCA on patholog.. The MDCT features predictive of diag.osis of SCA were microcystic appearance （22/28, 78.6%）, surface Iobulations （25/28, 89.3%） and central scar （9/28, 32.4%）. Stepwise log.stic reg.ession analysis showed that only microcystic appearance was sig.ificant for CT diag.osis of SCA （P = 0.0001）. The sensitivity, specificity and PPV of central scar and of combined microcystic appearance and Iobulations were 32.4%/100%/100% and 68%/100%/100%, respectively. The reader confidence was hig.er for lesions 〉 3 cm （P = 0.02） and for MDCT scans performed using.thin collimation （1.25-2.5 mm） compared to routine 5 mm collimation exams （P 〉 0.05）. CONCLUSION： Central scar on MDCT is diag.ostic of SCA but is seen in only one third of SCAs. Microcystic morpholog. is the most sig.ificant CT feature in diag.osis of SCA. A combination of microcystic appearance and surface Iobulations offers accuracy comparable to central scar with hig.er sensitivity.

关键词： Pancreas Serous cystadenoma Multidetector computed tomog.aphy Central scar Lobulations Microcystic

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

瞬态接触动力学的三维问题

引用

中国科学（A辑） 1996年第7期26卷 642-648页

作者：范天佑 H.g.hahn A.Voig. 北京理工大学材料科学中心 UniversityofKaiserslauternD-67663Kaiserslautern

发展了三维瞬态接触动力学问题的分析解法,并且得到了广义g.lin()定理.对于给定的相当普遍的接触应力,可以确定相应的接触位移,并且得到解析的形式;反过来,对于给定的相当普遍的接触位移,可以解析地确定其相应的接触应力.上述所指的普... 详细信息

发展了三维瞬态接触动力学问题的分析解法,并且得到了广义g.lin()定理.对于给定的相当普遍的接触应力,可以确定相应的接触位移,并且得到解析的形式;反过来,对于给定的相当普遍的接触位移,可以解析地确定其相应的接触应力.上述所指的普遍的给定物理量可以是X与y的任意阶多项式和时间t的任意瞬态函数.还针对不同接触区的几何特征和最典型的最常使用的7种固体介质进行了实例计算,所有计算结果均表明上述理论结果在数学上和物理上的精确性.

关键词：三维问题广义g.lin定理瞬态接触动力学

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Desig. of a Methane Monitoring.System for Landfill and Duct Emissions

引用

Natural Resources 2020年第11期11卷 520-529页

作者： Federico hahn g.udencio g.ande Irrig.tion Department Universidad Autonoma Chapingo Texcoco México IAUIA Universidad Autonoma Chapingo Texcoco México

Methane is released from waste disposal areas as a result from anaerobic decay of food. Methane causes more g.eenhouse effects than carbon dioxide so a methane monitoring.system is required to warn its release from g.... 详细信息

Methane is released from waste disposal areas as a result from anaerobic decay of food. Methane causes more greenhouse effects than carbon dioxide so a methane monitoring system is required to warn its release from gas emitting environments. The low explosive limit of methane is 5% in ambient air, so gas leakage is dangerous and can produce explosions. An entire head monitoring system was built around a MQ-4 methane gas sensor as it is cheap and reliable. The design proves to be flexible enough as it can measure CH4 emissions in ducts, CH4 in landfills at different depths and even in cattle barns. The measuring system head consists of a suction pump, solenoids, and a methane sensor. Measurements are taken 13 seconds after methane gas sucking. A timing of 100 seconds is required for purging the chamber before the second solenoid is turned-on. Devices temperature during operation was sampled with a thermal Flir-One camera and solenoid coil temperature was of 24.9˚C after a continuous operation of 30 seconds. As hoses for emission sampling become larger time for sampling increases as well as energy consumption.

关键词： Methane Detection MQ-4 Sensor Monitoring.Head Current Consumption

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：