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A comparison of cyanoacrylate to sutures for wound closure following acoustic transmitter insertion in rainbow trout

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Aquaculture and Fisheries 2021年第5期6卷 513-518页

作者： Jeremy Kientz Nathan Huysman michael e.barnes South Dakota Department of Game Fish and Parks4130 Adventure TrailRapid CitySD57702USA South Dakota Department of Game Fish and ParksMcNenny State Fish Hatchery19619 Trout LoopSpearfishSD57783USA

Tag retention,wound healing,wound closure,and tagged fish survival are critically important after surgical implantation of acoustic transmitters in *** study compared the use of sutures to cyanoacrylate adhesives and bandages for post-surgery wound *** rainbow trout Oncorhynchus mykiss were assigned to one of seven treatments:a control group where fish were only handled,two suture groups(tagged with dummy acoustic transmitters or non-tagged),and four cyanoacrylate adhesive groups(non-tagged,tagged with adipose fin applied as a biological bandage,tagged with anal fin applied,and non-tagged with water-proof bandage).Tag retention was significantly improved in adhesive with anal fin(89%)and tagged suture(78%)treatments when compared to only 11%tag retention in the adhesive with adipose fin *** redness severity increased over the 14 weeks of the study in the tagged and sutured fish,and in those receiving the waterproof *** redness severity was also significantly higher in the waterproof bandage and tagged and sutured treatments than both tagged adhesive treatments at the end of the *** gape was significantly more severe in the adhesive with adipose treatment than in the control,suture,tagged suture,and adhesive treatments,but no significant differences were observed between the adhesive with adipose treatment and the adhesive with anal fin or bandage *** gape never completely closed in the adhesive with adipose group,while both the tagged suture treatment and tagged adhesive with anal treatment wounds completely closed between four-and six-weeks *** results of this study indicate that cyanoacrylate adhesive used in conjunction with anal fin tissue is a suitable post-surgical treatment.

关键词： Surgery Acoustic transmitter Cyanoacrylate Rainbow trout Oncorhynchus mykiss

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Retention of fin clips and fin and operculum punch marks in rainbow trout

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Aquaculture and Fisheries 2022年第6期7卷 660-663页

作者： Alex J.Rosburg Jacob L.Davis michael e.barnes South Dakota Department of Game Fishand Parks4725 Jackson BoulevardRapid CitySD57702USA South Dakota Department of Game Fishand Parks4130 Adventure TrailRapid CitySD57702USA South Dakota Department of Game Fishand Parks19619 Trout Loop SpearfishSouth Dakota57783USA

Fin clips(complete fin removal)or punch marks(stamping of a hole)in fins or operculum are quick and inexpensive methods to identify individuals or groups of *** study evaluated the retention of 6 mm diameter punch marks on the operculum,caudal(upper and lower lobes),dorsal,pelvic,and anal fins,and fin clips on adipose,pectoral,pelvic,dorsal and anal fins of rainbow trout Oncorhynchus mykiss for 279 *** and survival were not significantly different among fish with the different mark types or *** the end of the experiment,100%of adipose clips,97%of pectoral and anal fin clips,and 93%of dorsal clips and pelvic fin clips were *** of punch marks was 57%and 50%for the lower and upper caudal fin lobe locations respectively,23%for the dorsal fin,and 3%for the *** pelvic or anal fin punch marks were identified at the end of the *** differences in retention among the treatment groups did not occur until 125 days post marking,after which all fin clip treatments had significantly greater retention than pelvic and dorsal punch *** 244 days,fin clips outperformed all punch mark locations.

关键词： Marking Rainbow trout Oncorhynchus mykiss Fin punch Fin clip Mark retention

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NeCAB family of neuronal calcium-binding proteins in health and disease

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Neural Regeneration Research 2025年第5期20卷 1236-1243页

作者： Diones Bueno michael K.e.Schafer Sudena Wang michael J.Schmeisser Axel Methner Institute for Molecular Medicine University Medical Center of the Johannes Gutenberg-UniversityMainzGermany Department of Anesthesiology University Medical Center of the Johannes Gutenberg-UniversityMainzGermany Institute of Anatomy University Medical Center of the Johannes Gutenberg-UniversityMainzGermany

The N-terminal eF-hand calcium-binding proteins 1–3(NeCAB1–3) constitute a family of predominantly neuronal proteins characterized by the presence of at least one eF-hand calcium-binding domain and a functionally less well characterized C-terminal antibiotic biosynthesis monooxygenase domain. All three family members were initially discovered due to their interactions with other proteins. NeCAB1 associates with synaptotagmin-1, a critical neuronal protein involved in membrane trafficking and synaptic vesicle exocytosis. NeCAB2 interacts with predominantly striatal G-protein-coupled receptors, while NeCAB3 partners with amyloid-β A4 precursor protein-binding family A members 2 and 3, key regulators of amyloid-β production. This demonstrates the capacity of the family for interactions with various classes of proteins. NeCAB proteins exhibit distinct subcellular localizations: NeCAB1 is found in the nucleus and cytosol, NeCAB2 resides in endosomes and the plasma membrane, and NeCAB3 is present in the endoplasmic reticulum and Golgi apparatus. The antibiotic biosynthesis monooxygenase domain, an evolutionarily ancient component, is akin to atypical heme oxygenases in prokaryotes but is not wellcharacterized in vertebrates. Prokaryotic antibiotic biosynthesis monooxygenase domains typically form dimers, suggesting that calcium-mediated conformational changes in NeCAB proteins may induce antibiotic biosynthesis monooxygenase domain dimerization, potentially activating some enzymatic properties. However, the substrate for this enzymatic activity remains uncertain. Alternatively, calcium-mediated conformational changes might influence protein interactions or the subcellular localization of NeCAB proteins by controlling the availability of protein–protein interaction domains situated between the eF hands and the antibiotic biosynthesis monooxygenase domain. This review summarizes what is known about genomic organization, tissue expression, intracellular localization, interac

关键词： calcium eF hand mitochondria nervous system signal transduction

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Mobile Sensing in the COVID-19 era:A Review

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Health Data Science 2022年第1期2022卷 56-68页

作者： Zhiyuan Wang Haoyi Xiong Mingyue Tang Mehdi Boukhechba Tabor e.Flickinger Laura e.barnes School of engineering and Applied Science University of VirginiaCharlottesvilleUSA Big Data Lab Baidu ResearchBaidu Inc.BeijingChina Department of Medicine University of VirginiaCharlottesvilleVirginiaUSA

Background. During the COVID-19 pandemic, mobile sensing and data analytics techniques have demonstrated their capabilitiesin monitoring the trajectories of the pandemic, by collecting behavioral, physiological, and mobility data on individual,neighborhood, city, and national scales. Notably, mobile sensing has become a promising way to detect individuals’ infectiousstatus, track the change in long-term health, trace the epidemics in communities, and monitor the evolution of viruses andsubspecies. Methods. We followed the PRISMA practice and reviewed 60 eligible papers on mobile sensing for monitoringCOVID-19. We proposed a taxonomy system to summarize literature by the time duration and population scale under mobilesensing studies. Results. We found that existing literature can be naturally grouped in four clusters, including remote detection,long-term tracking, contact tracing, and epidemiological study. We summarized each group and analyzed representative workswith regard to the system design, health outcomes, and limitations on techniques and societal factors. We further discussed theimplications and future directions of mobile sensing in communicable diseases from the perspectives of technology andapplications. Conclusion. Mobile sensing techniques are effective, efficient, and flexible to surveil COVID-19 in scales of timeand populations. In the post-COVID era, technical and societal issues in mobile sensing are expected to be addressed toimprove healthcare and social outcomes.

关键词： neighborhood summarized directions

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Acute and chronic excitotoxicity in ischemic stroke and late-onset Alzheimer's disease

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Neural Regeneration Research 2025年第7期20卷 1981-1988页

作者： Shan Ping Yu emily Choi michael QJiang Ling Wei Department of Anesthesiology Emory University School of MedicineAtlantaGAUSA Center for Visual and Neurocognitive Rehabilitation Atlanta Veterans Affairs Medical CenterDecaturGAUSA

Stroke and Alzheimer's disease are common neurological disorders and often occur in the same *** comorbidity of the two neurological disorders represents a grave health threat to older *** review presents a brief background of the development of novel concepts and their clinical *** activity of glutamatergic N-methyl-D-aspartate receptors and N-methyl-D-aspartate receptor-mediated Ca^(2+)influx is critical for neuronal *** ischemic insult induces prompt and excessive glutamate release and drastic increases of intracellular Ca^(2+)mainly via N-methyl-D-aspartate receptors,particularly of those at the extrasynaptic *** Ca^(2+)-evoked neuronal cell death in the ischemic core is dominated by necrosis within a few hours and days known as acute ***,mild but sustained Ca^(2+)increases under neurodegenerative conditions such as in the distant penumbra of the ischemic brain and early stages of Alzheimer's disease are not immediately toxic,but gradually set off deteriorating Ca^(2+)-dependent signals and neuronal cell loss mostly because of activation of programmed cell death *** on the Ca^(2+)hypothesis of Alzheimer's disease and recent advances,this Ca^(2+)-activated“silent”degenerative excitotoxicity evolves from years to decades and is recognized as a unique slow and chronic *** N-methyl-D-aspartate receptor subunit GluN3A,primarily at the extrasynaptic site,serves as a gatekeeper for the N-methyl-D-aspartate receptor activity and is neuroprotective against both acute and chronic *** stroke and Alzheimer's disease,therefore,share an N-methyl-D-aspartate receptor-and Ca^(2+)-mediated mechanism,although with much different time *** is thus proposed that early interventions to control Ca^(2+)homeostasis at the preclinical stage are pivotal for individuals who are susceptible to sporadic late-onset Alzheimer's disease and Alzheimer's disease-related

关键词： Ca^(2+)hypothesis cognitive deficits hyperactivity late-onset Alzheimer's disease neurodegeneration N-methyl-D-aspartate receptors N-methyl-D-aspartate receptor subunits pathogenesis preventive treatment

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Additive Manufacturing:Incremental Improvements to a Disruptive Technology

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Accounts of Materials Research 2021年第8期2卷 574-576页

作者： John e.barnes Kevin Slattery The.barnes Global Advisors PittsburghPennsylvaniaUnited States The.barnes Global Advisors St.LouisMissouriUnited States

Additive Manufacturing(AM)is disruptive and complex not only in its nature but also in what it can *** have always had difficulty absorbing complexity and disruption due to our skeptical nature and need to *** being a 3-dimensional solution is simply an example of how AM is disruptive because people are adept at thinking in two *** a technology as transformative as AM to progress,some assumptions have to be made and certain approximations have to be asserted and held to be true until they can be revisited *** we weigh the societal benefit that AM can and will bring,efficiency comes to the *** could be efficiency of energy use,efficiency of materials utilization,or efficiency in designs that are lighter and then use less *** matter what form efficiency takes,it impacts *** achieve a greater impact,AM must become more pervasive,and for it to become more pervasive,it must become more *** additional source of complexity in AM is the sheer number of process variables,such as feedstock,energy source,part geometry,and postprocessing,with more than 100 identified,1 not including the interrelationships between these *** similar numbers are present in other manufacturing processes,such as forging and casting,civilization has had between 200 and 5000 years to understand the variables in these processes,which is longer than society wants to wait in the case of AM.

关键词： casting Additive absorbing

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NMO拉伸再认识

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国外油气勘探 1993年第5期 576-579页

作者： Arthur e.barnes 刘学军

引言应用动校正(NMO)将地震反射资料中的非零炮检距记录道转换成看来好像是零炮检距的记录道,就会产生所不希望的畸变,叫做 NMO 拉伸(Buchholtz,1972)。NMO 拉伸把波形拉长,从而降低分辨率,因此有必要对 NMO 拉伸进行研究。Buchholtz(19... 详细信息

引言应用动校正(NMO)将地震反射资料中的非零炮检距记录道转换成看来好像是零炮检距的记录道,就会产生所不希望的畸变,叫做 NMO 拉伸(Buchholtz,1972)。NMO 拉伸把波形拉长,从而降低分辨率,因此有必要对 NMO 拉伸进行研究。Buchholtz(1972)给NMO 拉伸作了一个定性评价,Dunkin 和 Levin(1973)推导了它对窄波形振幅谱的影响,Yilmaz(1987)研究了它对主频的影响,这些研究工作都是近似的,都没有展示谱的畸变是

关键词： NMO拉伸瞬时频率瞬时功率谱非线性畸变

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Optimal orientations of discrete global grids and the Poles of Inaccessibility

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International Journal of Digital earth 2020年第7期13卷 803-816页

作者： Richard barnes energy&Resources Group BerkeleyUSA electrical engineering&Comptuer Science BerkeleyUSA

Spatial analyses involving binning often require that every bin have the same area,but this is impossible using a rectangular grid laid over the earth or over any projection of the *** global grids use hexagons,triangles,and diamonds to overcome this issue,overlaying the earth with equally-sized *** discrete global grids are formed by tiling the faces of a ***,the orientations of these polyhedra have been chosen to satisfy only simple criteria such as equatorial symmetry or minimizing the number of vertices intersecting ***,projection distortion and singularities in discrete global grids mean that such simple orientations may not be sufficient for all use ***,I present an algorithm for finding suitable orientations;this involves solving a nonconvex optimization *** a side-effect of this study I show that Fuller’s Dymaxion map corresponds closely to one of the optimal orientations I find.I also give new high-accuracy calculations of the Poles of Inaccessibility,which show that Point Nemo,the Oceanic Pole of Inaccessibility,is 15 km farther from land than previously recognized.

关键词： Discrete grid geographic information system(GIS) geoinformatics supercomputer projections spatial statistics

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2-D复地震道分析理论

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国外油气勘探 1997年第5期9卷 581-588页

作者： Arthur e.barnes 吴光大青海石油管理局勘探开发研究院

1-D复地震道分析概念容易引申到 2-D。2-D 的瞬时振幅和相位是标量,而 2-D 瞬时频率和带宽为垂直于局部波前的矢量,每一矢量是由一个数值和一个倾角所确定。两个独立的瞬时倾角测量值对应于瞬时视相速度和群速度。按照f-k或2-D正弦假频... 详细信息

1-D复地震道分析概念容易引申到 2-D。2-D 的瞬时振幅和相位是标量,而 2-D 瞬时频率和带宽为垂直于局部波前的矢量,每一矢量是由一个数值和一个倾角所确定。两个独立的瞬时倾角测量值对应于瞬时视相速度和群速度。按照f-k或2-D正弦假频滤波的准则,对陡反射倾角的瞬时倾角假频滤波,2-D频率和带宽适合于偏移资料,而1-D频率和带宽适合于未偏移资料。用比1-D少得多的计算量可有效地计算出2-D希尔伯特变换和2-D复地震道属性。在3-D情况下,振幅和相位仍是标量,但频率和带宽是具有大小、倾角和方位的3-D矢量。

关键词：复数道分析振幅包络 2-D复地震道地震勘探

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用于钻地弹头的备有存贮器的耐冲击高频PCM系统

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导弹与航天运载技术(中英文) 1984年第8期 47-51页

作者： David e.barnes 李伟范

为了适应钻地弹头增大试验数据量的要求,设计了一种比前用系统具有更大信号频响、更高分辨率、存贮容量更大的数字式遥测系统。新系统以3.2兆码/秒的速率将数据编成字长为8位的数字量存贮在640千码COMS存贮器中,待钻地弹头回收后读出。... 详细信息

为了适应钻地弹头增大试验数据量的要求,设计了一种比前用系统具有更大信号频响、更高分辨率、存贮容量更大的数字式遥测系统。新系统以3.2兆码/秒的速率将数据编成字长为8位的数字量存贮在640千码COMS存贮器中,待钻地弹头回收后读出。本文叙述钻地弹头试验计划以及为它而研制的新型遥测系统。

关键词：钻地弹头导弹弹头 PCM 存贮器存储器耐冲击

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