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Characteristics of patients with erectile dysfunction in a family physicianled erectile dysfunction clinic:Retrospective case series

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Family Medicine and Community Health 2017年第1期5卷 85-91页

作者： Lap Kin Chiang Cheuk-Wai Kam Kin-chung michael Yau Lorna Ng Family Medicine and General Outpatient Department Kwong Wah HospitalMongkokHong KongChina

Objectives:*** examine the characteristics of patients with erectile dysfunction in a family physician led erectile dysfunction clinic;*** review association of chronic disease spectrum and erectile dysfunction;*** review initial treatment pattern and ***:Retrospective case series ***:All consecutive patients seen in a regional hospital family physician led erectile dysfunction clinic from April 2014 to March *** outcome measures:*** severity of erectile dysfunction,based on International Index of Erectile Function(IIEF-5).*** associated chronic comorbidities of *** patterns and patient ***:One hundred and eighty three patients presented with erectile dysfunction(ED)with mean age 58.7(range 23 to 82)years old were seen during the study *** hundred and twenty seven patients(69.4%)had comorbidity of chronic diseases,including 50.8%had hypertension,38.8%had diabetes mellitus and 33.9%had *** mean body mass index was 25.2 kg/m2,the mean blood pressure was 137.3/79.5 mm Hg(1 mm Hg=0.133 kPa).According to IIEF-5 score,50.3%,30.6%and 18.6%had severe,moderate and mild erectile dysfunction *** average duration of ED before seeking medical help was 3.9 *** 5(PDE5)inhibitors were prescribed to 119 patients(65%),and 57.1%of them achieved good *** nine patients(15.8%)were referred to other specialty for further management,including 27.6%had contraindication for PDE5 ***:High proportion of erectile dysfunction patients had comorbitiy of chronic dis-eases.57.1%of those patients receiving PDE5 inhibitors showed good response.

关键词： Erectile dysfunction chronic diseases family physician

Exploiting fly models to investigate rare human neurological disorders

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Neural Regeneration Research 2025年第1期20卷 21-28页

作者： Tomomi Tanaka Hyung-Lok chung Department of Neurology Houston Methodist Research InstituteHoustonTXUSA Department of Neurology Weill Cornell Medical CollegeNew YorkNYUSA

Rare neurological diseases,while individually are rare,collectively impact millions globally,leading to diverse and often severe neurological *** attributed to genetic mutations that disrupt protein function or structure,understanding their genetic basis is crucial for accurate diagnosis and targeted *** investigate the underlying pathogenesis of these conditions,researchers often use non-mammalian model organisms,such as Drosophila(fruit flies),which is valued for their genetic manipulability,cost-efficiency,and preservation of genes and biological functions across evolutionary *** tools available in Drosophila,including CRISPR-Cas9,offer a means to manipulate gene expression,allowing for a deep exploration of the genetic underpinnings of rare neurological *** boasts a versatile genetic toolkit,rapid generation turnover,and ease of large-scale experimentation,making it an invaluable resource for identifying potential drug *** can expose flies carrying disease-associated mutations to various compounds,rapidly pinpointing promising therapeutic agents for further investigation in mammalian models and,ultimately,clinical *** this comprehensive review,we explore rare neurological diseases where fly research has significantly contributed to our understanding of their genetic basis,pathophysiology,and potential therapeutic *** discuss rare diseases associated with both neuron-expressed and glial-expressed *** cases include mutations in CDK19 resulting in epilepsy and developmental delay,mutations in TIAM1 leading to a neurodevelopmental disorder with seizures and language delay,and mutations in IRF2BPL causing seizures,a neurodevelopmental disorder with regression,loss of speech,and abnormal *** we explore mutations in EMC1 related to cerebellar atrophy,visual impairment,psychomotor retardation,and gain-of-function mutations in ACOX1 causing Mitchell ***-of-fun

关键词： ACOX1 Drosophila melanogaster glia lipid metabolism model organisms neuroinflammation neurologic disorders neuron rare disease VLCFA

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新战略化生存

商学院 2006年第4期 68-70页

作者： Nick Demos Steven chung michael Beck

突破性的新技术，全球化和高效率的资本市场使各种经济体与机构的动作环境发生了翻天覆地的变化，因此，仅仅以形成和维持长期市场地位为目标的传统的战略制订方法必须变革。

关键词：战略化资本市场制订方法市场地位新技术突破性经济体高效率全球化

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解决中国就业的办法

解决中国就业的办法

小阴唇整形术：当前小阴唇肥大的治疗方法和简化的分类系统

第三期中国现代化研究论坛

作者：钟思扬 michael chung

“解决中国就业的办法”是本人于2003年两会之时提交的几点建议之一。中国的现代化对就业和能源需求有着重大的影响,邓小平同志在一九七九年三月三十日党的理论工作务虚会上的讲话,看《邓小平文选》（一九七五——一九八二年）的“坚持... 详细信息

“解决中国就业的办法”是本人于2003年两会之时提交的几点建议之一。中国的现代化对就业和能源需求有着重大的影响,邓小平同志在一九七九年三月三十日党的理论工作务虚会上的讲话,看《邓小平文选》（一九七五——一九八二年）的“坚持四项基本原则”里邓小平同志说:“……中国式的现代化,必须从中国的特点出发。比方说,现代化的生产只需要较少的人就够了,而我们人品这样多,怎样两方面兼顾?不统筹兼顾,我们就会长期面对着一个就业不充分的社会问题。这里问题很多,需要全党做实际工作和理论工作的同志共同研究,我们也一定能找出适当的办法来妥善解决……,,中国人口多、劳动力总量大,这决定了中国的现代化所引起的就业问题的艰巨性、长期性。中国目前碰到的就业困难,是经济发展和结构调整中的问题,是前进中的问题,是发展中的问题,中国走中国特式的社会主义市场经济,中国政府一样没有权力叫企业公司去雇用多少员工。本文回顾了许多西方国家解决经济衰退中出现的失业问题的手段,然后提出了两个互相结合的办法去解决二十一世纪中国经济高速发展下出现的失业问题:一是社会保障制度;二是工作制度。中国政府可以立法规定工人每个星期只工作四天的工作制度。当中国完成现代化之时,相信三天的工作制度会在中国出现。这样的工作制度对人口老龄化的趋势和由此产生各种社会和经济问题也有所邦助。同时本文也论证了中国的现代化一定要有足够的能源才能够完成。当中国完成现代化之后,也一定要有足够的能源才能够维持。能源储备的安全是保持就业水平不可缺少的条件,也是维持国家安全和繁荣稳定不可缺少的条件。

关键词：就业能源需求现代化的生产中国人口多中国特式的社会主义市场经济经济发展中的就业问题经济衰退中的失业问题社会保障制度四天的工作制度三天的工作制度人口老龄化能源储备的安全

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中国美容整形外科杂志 2015年第6期26卷 I0013-I0025页

作者： Saba Motakef Jose Rodriguez-Feliz michael T. chung michael J. Ingargiola Victor W. Wong Ashit Patel 罗马琳达大学整形外科奥尔巴尼医学中心整形重建外科西奈山医院整形重建外科约翰霍普金斯大学整形重建外科美国加利福尼亚州罗马琳达

背景小阴唇整形术主要是解决小阴唇肥大引起的功能和外观问题。尽管其手术量逐渐增多，但仍缺少指导手术方法的数据。笔者对相关文献进行系统性复习，旨在制定简单、统一的小阴唇肥大分类表，并对当前小阴唇整形的技术和方法进行总结。... 详细信息

背景小阴唇整形术主要是解决小阴唇肥大引起的功能和外观问题。尽管其手术量逐渐增多，但仍缺少指导手术方法的数据。笔者对相关文献进行系统性复习，旨在制定简单、统一的小阴唇肥大分类表，并对当前小阴唇整形的技术和方法进行总结。方法用PubMed数据库进行系统的文献复习。审阅选定文献中的参考文献，并选出相关的文献。结果本研究对247篇文献进行了复习。根据入选标准，明确评估不同技术的前瞻性和回顾性研究、结果、并发症和患者的满意度，从中选取了19篇文献。共有1949例患者接受小阴唇整形术。总共采用了7种不同的手术方法，包括去上皮、直接切除、“W”形切除、楔形切除、联合切除、Z成形术和激光切除。每种方法的患者满意率为94％-100％。所有方法最常见的术后并发症是切口裂开（4．7％）。明确围手术期患者治疗的关键部分。结论小阴唇整形是安全的，且满意率很高。然而，当前的方法仍极其多样化。作者以大阴唇（不是阴道口）到小阴唇外侧缘距离为基础，提出了一种精简的分类系统。围手术期患者治疗的关键部分包括患者的麻醉、切除方法、伤口缝合和术后护理。用标准的分类系统行进一步的随机对照研究，旨在更好地对比不同的技术，选出更好的方法。

关键词：小阴唇肥大分类系统治疗方法整形术患者满意率文献复习系统性复习术后并发症

Crystallization Modulation and Holistic Passivation Enables Efficient Two‑Terminal Perovskite/CuIn(Ga)Se_(2)Tandem Solar Cells

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Nano-Micro Letters 2025年第1期17卷 205-215页

作者： Cong Geng Kuanxiang Zhang Changhua Wang chung Hsien Wu Jiwen Jiang Fei Long Liyuan Han Qifeng Han Yi‑Bing Cheng Yong Peng State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of TechnologyWuhan 430070People’s Republic of China Triumph Photovoltaic Materials Co. Ltd.No.1001 Yannan AvenueHigh‑Tech Development DistrictBengbuAnhui 233000People’s Republic of China College of Materials Science and Engineering Guilin University of TechnologyGuilin 541004People’s Republic of China State Key Laboratory of Metal Matrix Composites Shanghai Jiao Tong UniversityShanghai 200240People’s Republic of China

Two-terminal(2-T)perovskite(PVK)/CuIn(Ga)Se_(2)(CIGS)tandem solar cells(TSCs)have been considered as an ideal tandem cell because of their best bandgap matching regarding to Shockley–Queisser(S–Q)***,the nature of the irregular rough morphology of commercial CIGS prevents people from improving tandem device *** this paper,D-homoserine lactone hydrochloride is proven to improve coverage of PVK materials on irregular rough CIGS surfaces and also passivate bulk defects by modulating the growth of PVK *** addition,the minority carriers near the PVK/C60 interface and the incompletely passivated trap states caused interface recombination.A surface reconstruction with 2-thiopheneethylammonium iodide and N,N-dimethylformamide assisted passivates the defect sites located at the surface and grain ***,LiF is used to create this field effect,repelling hole carriers away from the PVK and C60 interface and thus reducing *** a result,a 2-T PVK/CIGS tandem yielded a power conversion efficiency of 24.6%(0.16 cm^(2)),one of the highest results for 2-T PVK/CIGS TSCs to our *** validation underscores the potential of our methodology in achieving superior performance in PVK/CIGS tandem solar cells.

关键词： PVK/CIGS TSCs Irregular rough surfaces Modulating the growth PVK/C60 interface recombination

Dual‑Donor‑Induced Crystallinity Modulation Enables 19.23% Efficiency Organic Solar Cells

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Nano-Micro Letters 2025年第3期17卷 376-388页

作者： Anhai Liang Yuqing Sun Sein chung Jiyeong Shin Kangbo Sun Chaofeng Zhu Jingjing Zhao Zhenmin Zhao Yufei Zhong Guangye Zhang Kilwon Cho Zhipeng Kan Center On Nanoenergy Research Institute of Science and Technology for Carbon Peak&NeutralitySchool of Physical Science&TechnologyGuangxi UniversityNanning 530004People’s Republic of China Department of Chemical Engineering Pohang University of Science and TechnologyPohang 37673South Korea College of New Materials and New Energies Shenzhen Technology UniversityShenzhen 518118People’s Republic of China Zhejiang Engineering Research Center for Fabrication and Application of Advanced Photovoltaic Materials School of Materials Science and EngineeringNingboTech UniversityNingbo 315100People’s Republic of China State Key Laboratory of Featured Metal Materials and Life-Cycle Safety for Composite Structures Nanning 530004People’s Republic of China

Trap-assisted charge recombination is one of the primary limitationsof restricting the performance of organic solar cells. However, effectivelyreducing the presence of traps in the photoactive layer remains ***, wide bandgap polymer donor PTzBI-dF is demonstrated as an effectivemodulator for enhancing the crystallinity of the bulk heterojunction active layerscomposed of D18 derivatives blended with Y6, leading to dense and orderedmolecular packings, and thus, improves photoluminescence quenching *** a result, the photovoltaic devices exhibit reduced trap-assisted charge recombinationlosses, achieving an optimized power conversion efficiency of over 19%.Besides the efficiency enhancement, the devices comprised of PTzBI-dF as athird component simultaneously attain decreased current leakage, improved chargecarrier mobilities, and suppressed bimolecular charge recombination, leading toreduced energy losses. The advanced crystalline structures induced by PTzBI-dFand its characteristics, such as well-aligned energy level, and complementaryabsorption spectra, are ascribed to the promising performance *** findings suggest that donor phase engineering is a feasible approach to tuning the molecular packings in the active layer, providingguidelines for designing effective morphology modulators for high-performance organic solar cells.

关键词： Trap-assisted charge recombination Photoluminescence Miscibility Current leakage Power conversion efficiency

脂肪移植的研究：第一部分注射技术对体外脂肪成活率和体内体积保持的作用

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中国美容整形外科杂志 2014年第10期25卷 I0005-I0012页

作者： michael T. chung Kevin J. Paik David A. Atashroo Jeong S. Hyun Adrian McArdle 魏峰高景恒张晨斯坦福大学医学院Hagey儿科再造医学实验室整形再造外科中心外科部干细胞生物学与再生医学中心美国加利福尼亚州斯坦福斯坦福大学材料科学、工程学及生物工程学部门洛帕克 TauTona研究组门洛帕克帕洛阿尔托外科中心帕洛阿尔托《中国美容整形外科杂志》编辑部大连大学附属新华医院整形外科

目的脂肪移植在修复全身多部位软组织缺陷方面越来越流行。但其远期效果取决于尽可能地减小移植过程中对脂肪组织的损伤，以增加其在受区的存活率。本研究中，将对2种注射方法移植后脂肪的生物学特性进行对比。方法从5例女性供体获取脂... 详细信息

目的脂肪移植在修复全身多部位软组织缺陷方面越来越流行。但其远期效果取决于尽可能地减小移植过程中对脂肪组织的损伤，以增加其在受区的存活率。本研究中，将对2种注射方法移植后脂肪的生物学特性进行对比。方法从5例女性供体获取脂肪抽吸物样本，并对应用改良Coleman技术或一种自动低剪切力装置注射后脂肪的细胞活性、增殖能力和脂解作用进行评估。对微处理、未注射的脂肪进行对比。利用改良Coleman技术或脂肪组织注射器，将脂肪注射移植于免疫缺陷小鼠头皮下，并于12周后测量体积保持情况。最后，对移植脂肪进行组织学分析。结果利用脂肪组织注射器注射移植的脂肪，其脂肪活性和细胞增殖能力明显比改良Coleman技术高。相反，采用自动装置注射脂肪，分解的量较少。移植后4、6、8、12周，体内脂肪的容量要比改良Coleman技术的脂肪容量高。这表明，该注射装置移植的脂肪组织学活性高，且损伤率低。结论注射后组织的生物学特性反映了脂肪置入技术的破坏、损伤程度，我们的体内和体外研究资料均提示应用自动低剪切力装置的方法优于改良Coleman技术。

关键词：脂肪移植体内脂肪注射技术脂肪成活率体积体外脂肪注射移植细胞增殖能力

Microplastic and nanoplastic exposure and risk of diabetes mellitus

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World Journal of Clinical Cases 2025年第3期13卷 24-29页

作者： Hui-Yi Hsiao chung-Yi Nien Ruei-Feng Shiu Wei-Chun Chin Tzung-Hai Yen Department of Biomedical Sciences College of MedicineChang Gung UniversityTaoyuan 33302TaiwanChina Center for Tissue Engineering Chang Gung Memorial HospitalLinkouTaoyuan 33305TaiwanChina Department of Life Sciences National Central UniversityZhongli 320317TaoyuanTaiwanChina Center of Excellence for The Oceans Taiwan Ocean UniversityKeelung 20224TaiwanChina Institute of Marine Environment and Ecology Taiwan Ocean UniversityKeelung 20224TaiwanChina Department of Chemical and Materials Engineering University of California MercedMercedCA 95343United States Department of Nephrology Clinical Poison CenterChang Gung Memorial HospitalLinkou 33305TaoyuanTaiwanChina School of Traditional Chinese Medicine College of MedicineChang Gung UniversityTaoyuan 33302TaiwanChina

The issue of plastic pollutants has become a growing *** microplastics(MPs)(particle size<5 mm)and nanoplastics(NPs)(particle size<1μm)can cause DNA damage,cytotoxicity,and oxidative stress in various *** primary known impacts of microplastic/nanoplastic are observed in the liver and respiratory system,leading to hepatotoxicity and chronic obstructive pulmonary *** research on the effects of MPs and NPs on diabetes is still in its early stages,there are potential *** editorial highlights the risk to diabetics from co-exposure to contaminants and MPs/NPs,supported by evidence from animal studies and the various chemical compositions of MPs/NPs.

关键词： Microplastics Nanoplastics Plastic pollution,Diabetes mellitus Insulin resistance