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Genes & Diseases 2024年第3期11卷 148-150页

作者： Chen Tan Lingwa Wang Yifan Yang Shizhi He George G.Chen Jason YK.Chan michael cf.tong C.A.van Hasselt Wenbin Xu Ling Feng Ru Wang Jugao Fang Department of Otolaryngology Head and Neck Surgery Beijing Tongren HospitalCapital Medical UniversityBeijing 100730China Key Laboratory of Otolaryngology Head and Neck Surgery(Ministry of Education of China) Beijing Institute of OtolaryngologyBeijing 100730China Department of Otorhinolaryngology Head and Neck SurgeryThe Chinese University of Hong KongPrince of Wales HospitalHongKong SAR999077China Department of Medical Genetics Institute of Basic Medical ScienceChinese Academy of Medical Science&Peking Union Medical CollageBeijing 100730China

Locoregionally advanced laryngeal and hypopharyngeal cancers(LA-LHCs)are traditionally treated with surgery followed by postoperative radiotherapy,which impairs speech and swallowing functions and reduces the quality of life.^(1,2)The use of induction chemotherapy(IC)as a larynxpreserving approach for LA-LHCs has been verified and refined.^(3)However,the short-term tumor response to IC varies,non-responders usually show poor survival and little benefit.

关键词： chemotherapy laryngeal surgery

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耳鼻咽喉-头颈外科的微创手术进展

耳鼻咽喉-头颈外科的微创手术进展

中华医学会第十次全国耳鼻咽喉-头颈外科学术会议

作者： michael cf tong Professor Department of Otorhinolaryngology Head and Neck Sugery

概述耳、鼻、喉具有开展微创手术(MIS)的天然解剖条件。也难怪耳鼻咽喉科成为最早接受微创这一概念的手术领域。50年前,当双目显微镜经改造后用于耳部手术时,MIS 在 ENT 的应用就开始了。当泌尿学家使用 Hopkin 镜时,ENT 专家已经在使...

概述耳、鼻、喉具有开展微创手术(MIS)的天然解剖条件。也难怪耳鼻咽喉科成为最早接受微创这一概念的手术领域。50年前,当双目显微镜经改造后用于耳部手术时,MIS 在 ENT 的应用就开始了。当泌尿学家使用 Hopkin 镜时,ENT 专家已经在使用硬管内窥镜开展鼻内的手术了。讨论 MIS 在耳科的应用在 MIS 使用之前,耳部疾病的治疗只能开展简单的操作比如脓肿引流。

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喉罩麻醉和经皮声带注射

喉罩麻醉和经皮声带注射

中华医学会第十次全国耳鼻咽喉-头颈外科学术会议

作者： Gordon Soo June Yeo michael cf tong Department of Otorhinolaryngology-Head & Neck Surgery Prince of Wales Hospital The Chinese University of Hong Kong Hong Kong SAR

经皮经环甲膜径路喉部注射是一种简易的途经,其快速直达过程使注射器针头系统仅需非常少的填充剂,任何类型可注射填充剂都可使用。经皮肤由环甲膜途径进行喉头注射是一种欠标准的途径。这种方式快速直接,需要注射器针头,任何类型的可注...

经皮经环甲膜径路喉部注射是一种简易的途经,其快速直达过程使注射器针头系统仅需非常少的填充剂,任何类型可注射填充剂都可使用。经皮肤由环甲膜途径进行喉头注射是一种欠标准的途径。这种方式快速直接,需要注射器针头,任何类型的可注射的填充剂均可使用。这种途径要在纤维光学引导下,主要在局部阻滞麻醉下进行,还要有此项技术相关的实践经验。作者对这种方式进行了改进,在喉部麻痹处注射特氟隆或自体脂肪。当预计患者会出现不适

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香港汽钵(Hong Kong Steam-bowl)法声门上喉成形术——用于治疗玩固性误吸所致口咽性吞咽困难的一项创新性技术

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香港汽钵(Hong Kong Steam-bowl)法声门上喉成形术——用于治疗玩...

中华医学会第十次全国耳鼻咽喉-头颈外科学术会议

作者： Peter KM Ku Victor Abdullah michael cf tong Andrew van Hasselt Department of Otorhinolaryngology-Head and Neck Surgery Prince of Wales Hospital and United Christian HospitalChinese University of Hong KongHong Kong Special Administrative RegionChina

目的报告香港汽钵法声门上喉成形术治疗玩固性误吸所致口咽性吞咽困难的一项创新性技术初步经验。方法 10例口咽性吞咽困难伴误吸患者,拒绝行非经口饮食,而行此手术试图阻止吞咽时的喉部误吸。全部病例均行吞咽时的纤维内镜检查和电视...

目的报告香港汽钵法声门上喉成形术治疗玩固性误吸所致口咽性吞咽困难的一项创新性技术初步经验。方法 10例口咽性吞咽困难伴误吸患者,拒绝行非经口饮食,而行此手术试图阻止吞咽时的喉部误吸。全部病例均行吞咽时的纤维内镜检查和电视透视检查从而作吞咽评估。手术指证包括与胸部感染相关的误吸、喉部内收肌反射重度受损所致误吸、误吸而行饮食和行为矫正失败、以及误吸康乐治疗失败和不可能康复。全部患者均拒绝非经口饮食,即鼻饲管或胃造瘘。手术前先行气管切开术,作舌骨下和咽侧切口以便于做垂直的声门上关闭,在会厌顶部留一小缝隙用于发音。

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Fossils of Macaca mulatta from Tianyuan Cave, with Notes on Some Previously Unpublished Specimens of Macaca from Zhoukoudian Area

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Acta Geologica Sinica(English Edition) 2014年第5期88卷 1397-1408页

作者： tong Haowen Key Laboratory of Vertebrate Evolution and Human Origins of Chinese Academy of Sciences Institute of Vertebrate Paleontology and Paleoanthropology Chinese Academy of Sciences

The recently discovered macaque fossils, including isolated teeth and mandible fragments, from Tianyuan Cave and the juvenile maxilla from Wanglaopu Cave near Zhoukoudian can be identified as Macaca mulatta; they represent the first recognized occurrence of fossil M. mulatta in the far north of China. Some previously unearthed but still unpublished Macaca specimens were also studied, including a cranium and the associated mandible from CKT Loc.13A, a maxilla and a mandible from Loc.1, a mandible from Loc.4, and a maxilla from Loc.20, as well as a mandible with complete toothrow from Zhoukoudian but without locality details, all of them can be referred to M. robusta. The study shows M. robusta is more closely related to M. mulatta than to M. anderssonL Zhoukoudian is the richest area of Macacina fossils in North China, totally 2 genera and 4 species were once recognized from 9 localities, namely, Procynocephalus wimani, M. cf. anderssoni, M. robusta and M. mulatta. The fossil records of Macacina in Zhoukoudian area were almost continuous through the Quaternary Period, and it＇s reasonable to assume that Zhoukoudian used to be an evolutionary center for macaques in North China. Therefore, the macaque population of M. mulatta once existed decades ago around Beijing probably originated from the Pleistocene ancestors in the local area, rather than being human-introduced as previously thought.

关键词： Macaca mulatta Macaca robusta Tianyuan Cave Zhoukoudian Pleistocene

MEDPOR RECONSTRUCTION FOR SADDLE NOSE DEFORMITY-A CASE ILLUSTRATION

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MEDPOR RECONSTRUCTION FOR SADDLE NOSE DEFORMITY-A CASE ILLUS...

中华医学会第十次全国耳鼻咽喉-头颈外科学术会议

作者： Gordon Soo Frederick Wong Micheal cf tong Division of Facial Phstic Surgery Department of Otorhinolaryngology-Head & Neck Surgery The Chinese University of Hong Kong Prince of Wales Hospital Hong Kong SAR

A 57 year old Chinese lady presented to our clinic with a saddle nose deformity following a history of nasal infection with reported fever.A full ENT examination revealed loss of the cartilaginous septum,saddling of the mid-third of the nasal dorsum,caudal columella retraction and a bulbous nasal *** including a white cell count,ESR,anti-nuclear cytoplasmic antibody titres and syphilis serology were all normal. The client requested for her saddling to be *** full counseling,it was mutually decided

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Improved Synthesis of Icaritin and Total Synthesis of β-Anhydroicaritin

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Chemical Research in Chinese Universities 2019年第4期35卷 616-620页

作者： tong Jie LIU Chang WANG Bo CAS Key Laboratory of High-petformance Synthetic Rubber and Its Composite Materials Key Laboratory of Green Chemistry and Process of Jilin ProvinceChangchun Institute of Applied Chemistry Chinese Academy cf SciencesChangchun 130022P. R.China University of Chinese Academy of Sciences Beijing 100049P. R. China University of Science and Technology of China Hefei 230026P. R.China

Natural products icaritin and β-anhydroicaritin with P-glycoprotein(P-gp) inhibitory activities were ciently synthesized in nine steps from commercially available phloroglucinol. A modified Algar-Flynn-Oyamada cyclization and relay Claisen-Cope rearrangement were employed in this concise route. Oiir synthesis offers opportunities to synthesize various icariin analogues for biological and pharmacological investigations.

关键词： Icaritin Flavonol Regioselectivity Algar-Flynn-Oyamada

Evaluation of Three Harvest Control Rules for Bigeye Tuna(Thunnus obesus) Fisheries in the Indian Ocean

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Journal of Ocean University of China 2014年第5期13卷 811-819页

作者： tong Yuhe CHEN Xinjun Dale Kolody Fisheries Research Institute of Hainan Province College of Marine Sciences Shanghai Ocean University The Key Laboratory of Sustainable Exploitation of Oceanic Fisheries of Ministry of Education Shanghai Ocean University Indian Ocean Tuna Commission Secretariat

The stock of Bigeye tuna(Thunnus obesus) in the Indian Ocean supports an important international fishery and is considered to be fully exploited. The responsible management agency, the Indian Ocean Tuna Commission(IOTC), does not have an explicit management decision-making framework in place to prevent over-fishing. In this study, we evaluated three harvest control rules, i) constant fishing mortality(cf), from 0.2 to 0.6, ii) constant catch(CC), from 60000 to 140000 t, and iii) constant escapement(CE), from 0.3 to 0.7. The population dynamics simulated by the operating model was based on the most recent stock assessment using Stock Synthesis version Ⅲ(SS3). Three simulation scenarios(low, medium and high productivity) were designed to cover possible uncertainty in the stock assessment and biological parameters. Performances of three harvest control rules were compared on the basis of three management objectives(over 3, 10 and 25 years): i) the probability of maintaining spawning stock biomass above a level that can sustain maximum sustainable yield(MSY) on average, ii) the probability of achieving average catches between 0.8 MSY and 1.0 MSY, and iii) inter-annual variability in catches. The constant escapement strategy(CE=0.5), constant fishing mortality strategy(F=0.4) and constant catch(CC=80000) were the most rational among the respective management scenarios. It is concluded that the short-term annual catch is suggested at 80000 t, and the potential total allowable catch for a stable yield could be set at 120000 t once the stock had recovered successfully. All the strategies considered in this study to achieve a ‘tolerable' balance between resource conservation and utilization have been based around the management objectives of the IOTC.

关键词： Thunnus obesus harvest control rule management strategy evaluation fishery management Indian Ocean

Mechanical Property, Oxidation and Ablation Resistance of C/C–ZrB_2–ZrC–SiC Composite Fabricated by Polymer Infiltration and Pyrolysis with Preform of C_f/ZrB_2

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Journal of Materials Science & Technology 2017年第5期33卷 481-486页

作者： Dong Huang Mingyu Zhang Qizhong Huang Liping Wang Kai tong College of Materials Science and Engineering Hunan University State Key Laboratory for Powder Metallurgy Central South University

CJC-ZrB2-ZrC-SiC composites were fabricated by polymer infiltration and pyrolysis （PIP） with a preform of G/ZrB2. The carbon fibers and the resin carbon were coated with ceramic layer after PIP in the com- posites. The composite presents a pseudo-plastic fracture due to deflection of cracks and pullout of fibers. The composite has a higher bending strength by this method in comparison with the conventional PIP process due to fewer heat treatment cycles. The static oxidation test shows that the mass loss of the composites is no more than 1% after 20 rain oxidation at 1100 ~C. The ＂core-shell＂ structure between ZrC-SiC ceramic and other phases plays a positive role in preventing the inward diffusion of oxygen. The ablation resistance of the C/C-ZrB2-ZrC-SiC composite samples was tested using a plasma generator. After ablation for 120 s, the mass and linear ablation rates of the composites are 4.65 mg cm-2 s-1 and 2.46 μm s-1, respectively. The short carbon layer shows a better ablation resistance than the nonwoven carbon fabric layer after the ceramic coating is peeled off because of its higher ceramic content.

关键词： C/C composite Ceramic-matrix composites High temperature corrosion

Nasopharyngectomy at the Prince of Wales Hospital in Hong Kong-Does the operation justify the complications?

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Nasopharyngectomy at the Prince of Wales Hospital in Hong Ko...

2005国际暨第八届全国头颈肿瘤大会

作者： AC Vlantis KY Tsang KT Wong cf tong CA van Hasselt Division of Otorhinolaryngology Department of SurgeryThe Chinese University of Hong KongPrince of Wales HospitalHong KongChina. Division of Otorhinolaryngology Department of SurgeryThe Chinese University of Hong KongPrince of Wales HospitalHong KongChina. Department of Diagnostic Radiology ＆ Organ Imaging The Chinese University of Hong KongPrince of Wales HospitalHong KongChina. Division of Otorhinolaryngology Department of SurgeryThe Chinese University of Hong KongPrince of Wales HospitalHong KongChina. Division of Otorhinolaryngology Department of SurgeryThe Chinese University of Hong KongPrince of Wales HospitalHong KongChina.

＜正＞ The primary treatment for nasopharyngeal carcinoma is radiotherapy or *** resection may be possible for local residual orrecurrent disease,but the close proximity of vital structures to the nasopharynxmakes the surgery *** various surgical approaches to the nasopharynx allhave their own problems and *** study aims determine the approachassociated with the lowest morbidity.

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