检索结果-南通市图书馆

A matter of time： Temporal variation in the introduction history and population genetic structuring of an invasive lizard

在线全文

学校读者我要写书评

暂无评论

Current Zoology 2015年第3期61卷 456-464页

作者： HalmahMOULE Kirilee CHAPLIN Rebecca D. bRAY Kimberly A. MILLER michael b. THOMSON David G. CHAPPLE School of biological Sciences Monash University Clayton Victoria 3800 Australia Department of Sciences Museum Victoria Victoria 3001 Australia School of biological Sciences University of Sydney Sydney NSW 2006 Australia Allan Wilson Centre for Molecular Ecology and Evolution School of Biological Sciences Victoria University of Wellington Wellington 6140 New Zealand

Invasive species are considered one of the greatest threats to native ecosystems, second only to habitat loss and frag- mentation. Despite this, the temporal dynamics of invasions are poorly understood, with most studies focusing on a single time point, providing us with only a snapshot of the biology and genetics of the invader. We investigated the invasion of Lord Howe Island by the delicate skink Lampropholis delicata and assessed the introduction history and genetic structure of this species over a 5-year period. Using genetic data taken from 2007, and again in 2011/12, we examined changes in the population genetic struc- ture （whether new haplotypes had been introduced to the island, and shifts in haplotype frequencies） of the species on the island between these two time points. No new haplotypes were introduced to the island between 2007 and 2011/12; however, significant shifts in haplotype frequencies across the island were detected. We conclude that the delicate skink is expanding its range into the southern regions of the island and that the haplotype frequencies on Lord Howe Island are still in a state of highly dynamic flux. Our study highlights the importance of considering invasions as dynamic and studying them in such a way that enable us to better manage their impacts

关键词： biological invasion Genetic admixture Lampropholis delicata Lord Howe Island Population genetics,Unintentional introduction

Hole-doping of mechanically exfoliated graphene by confined hydration layers

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2015年第9期8卷 3020-3026页

作者： Tjeerd R. J. bollmann Liubov Yu. Antipina Matthias Temmen michael Reichling Pavel b. Sorokin Inorganic Materials Science MESA+ Institute for Nanotechnology P. O. Box 217 7500AE Enschede The Netherlands Fachbereich Physik Universitat OsnabrClck BarbarastraBe 7 OsnabrClck 49076 Germany Moscow Institute of Physics and Technology Dolgoprudny 141700 Russian Federation Siberian Federal University Krasnoyarsk 660041 Russian Federation National University of Science and Technology MISiS Moscow 119049 Russian Federation

by the use of non-contact atomic force microscopy （NC-AFM） and Kelvin probe force microscopy （KPFM）, we measure the local surface potential of mechanically exfoliated graphene on the prototypical insulating hydrophilic substrate of CAF2（111）. Hydration layers confined between the graphene and the CaF2 substrate, resulting from the graphene＇s preparation under ambient conditions on the hydrophilic substrate surface, are found to electronically modify the graphene as the material＇s electron density transfers from graphene to the hydration layer. Density functional theory （DFT） calculations predict that the first 2 to 3 water layers adjacent to the graphene hole-dope the graphene by several percent of a unit charge per unit cell.

关键词： graphene,non-contact atomic forcemicroscopy (NC-AFM,KPFM),liquid-solid interfacestructure,electronic transport innanoscale materials andstructuresgraphene,non-contact atomic forcemicroscopy (NC-AFM,KPFM),liquid-solid interfacestructure,electronic transport innanoscale materials andstructures

Climate change impacts on streamflow,water quality,and best management practices for the Shell and Logan Creek Watersheds in Nebraska,USA

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Agricultural and biological Engineering 2012年第1期5卷 13-34页

作者： michael W.Van Liew Song Feng Tapan b.Pathak Department of biological Systems Engineering University of Nebraska-LincolnNEUSA School of Natural Resources University of Nebraska-LincolnNEUSA

Improvements in the management of water,sediment,and nutrients under future climatic conditions are needed to ensure increased crop and livestock production to meet greater global needs and the future availability of water for competing demands and protection against adverse water quality *** study determined the impacts of future climate change scenarios on streamflow,water quality,and best management practices(bMPs)for two watersheds in Nebraska,*** Soil and Water Assessment Tool(SWAT)was employed to simulate streamflow,sediment,total nitrogen(N)and total phosphorus(P)from the Shell Creek Watershed near Columbus,Nebraska and the Logan Creek Watershed near Sioux City,*** streamflow and water quality records for the two watersheds were used to calibrate model parameters that govern streamflow,sediment,and nutrient responses in *** each watershed,precipitation,air temperature,and CO2 concentrations were input to SWAT for four climatic conditions:a baseline condition for the 1980 to 2000 period and the SRES A2,A1b,and b1 climate scenarios for a future period from 2040 to *** from this study suggest that under the three future climate change scenarios,sediment losses are expected to be about 1.2 to 1.5 times greater than the baseline condition for Shell Creek and 2 to 2.5 times greater for Logan Creek;total N losses are expected to be about 1.2 to 1.4 times greater for Shell Creek and 1.7 to 1.9 times greater for Logan *** to the baseline,total P losses under the future climate scenarios are projected to be about the same for Shell Creek and 1.5 to 1.7 times greater for Logan *** from this study also suggest that future projected increases in both precipitation and CO2 concentration account for net increases in streamflow,but in different ways on each watershed.

关键词： hydrology water quality model calibration climate change SWAT

Decline of semen quality during IVF is not associated with subjective male stress

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Journal of Andrology 2014年第4期16卷 597-601页

作者： Kazem Nouri brigitte Litschauer michael Sator Denise Tiringer Johannes Ott Katherina Walch Lukas A Hefler Clemens b Tempfer Department of Obstetrics and Gynecolog Department of Clinical Pharmacology Medical University of Vienna Vienna Department of Obstetrics and Gynecology Krankenhaus Barmherzige Schwestern Linz Austria Department of Obstetrics and Gynecology Ruhr University Bochum Bochum Germany.

The aim of the present study was to assess if semen quality declines during in vitro fertilization （IVF） and whether or not this phenomenon is triggered by chronic male stress. In order to test this hypothesis, we first investigated a retrospective cohort of 155 male IVF patients （testing cohort）. Subsequently, we started a prospective cohort study in men undergoing their first IVF and assessed semen quality and subjective male chronic stress using a validated tool, i.e. the Fertility Problem Inventory （FPI） questionnaire. The association between stress and sperm quality decline measured 4-6weeks before the start of IVF （T1） and at the day of oocyte retrieval （T2） was the primary outcome. Live birth rate, first trimester abortion and rate of poor responders were secondary outcomes. In the testing cohort, mean progressive motility, but not mean sperm density significantly declined. There were 78/154 （51%） men who showed a decline in semen density and 50/154 （32%） men who showed a decline in progressive motility. In the validation cohort, progressive motility declined, whereas, sperm density increased from T1 to T2. Of 78 men, 27 men had increased stress （FPI-score 〉 146）. Sperm density and progressive motility were not significantly different in men with and without stress. However, in the presence of male stress, couples had a higher rate of poor responders, miscarriages and a lower rate of live births. Subjective stress is not associated with a decline in semen quality observed during IVF but may be associated with adverse ore^nancv outcome.

关键词： in vitro fertilization questionnaire semen quality stress

人工智能和放射科医生对乳腺X线筛查的全民评估

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

国际医学放射学杂志 2024年第4期 503-503页

作者： J.Kühl M.T.Elhakim S.W.Stougaard b.S.b.Rasmussen M.nielsen O.Gerke 高佳音

摘要目的基于对筛查区域内全部适宜人群的乳腺X线摄影，比较初诊乳腺放射科医生和人工智能（AI）在乳腺癌检测方面的价值。方法纳入2014年8月4日—2018年8

关键词：

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

癌症化学预防:过去,现在和未来(英文)

化学进展 2013年第9期25卷 1421-1428页

作者： michael b. Sporn Karen T. Liby Department of Pharmacology Geisel School of Medicine at Dartmouth Hanover New Hampshire 03755 USA

本文将对癌症化学预防的发展历史、研究现状及其未来前景作一简要评述,主要包括以下内容:癌症化学预防的科学基础,正在使用的癌症化学预防药物,对新合成药物的需求,以及面临的挑战等。本文尤其强调了联合用药在有效的癌症预防中的重要性。

关键词：化学预防癌症选择性雌激素受体调控剂 rexinoids 三萜

Evaluation of root traits and water use efficiency of different cotton genotypes in the presence or absence of a soil-hardpan

在线全文

学校读者我要写书评

暂无评论

The Crop Journal 2021年第4期9卷 945-953页

作者： Ricardo St Aime Grace Rhodes michael Jones bTodd Campbell Sruthi Narayanan Department of Plant and Environmental Sciences Clemson UniversityClemsonSC 29634USA Medical University of South Carolina SC 29425USA Pee Dee Research and Education Center Clemson UniversityFlorenceSC 29506USA USDA-ARS Coastal Plain SoilWater and Plant Conservation ResearchFlorenceSC 29501USA

Cotton(Gossypium spp.) is an important fiber and oil crop grown worldwide. Water and nutrient stresses are major issues affecting cotton production globally. Root traits are critical in improving water and nutrient uptake and maintaining plant productivity under optimal as well as drought ***, root traits have rarely been utilized in cotton breeding programs, a major reason being the lack of information regarding genetic variability for root traits. The objective of this research was to evaluate ten selected cotton genotypes for root traits and water use efficiency. The tested genotypes included germplasm lines(PD 1 and PD 695) and cultivars that are currently grown in the southeastern USA(PHY 499 WRF, PHY 444 WRF, PHY 430 W3 FE, DP 1646 b2 XF, DP 1538 b2 XF, DP 1851 b3 XF, NG5007 b2 XF, and ST 5020 GLT). Experiments were conducted under controlled environmental conditions in 2018 and 2019. A hardpan treatment was included in the second year to evaluate the effect of a soil hardpan on root traits and water use efficiency. Genotype PHY 499 WRF ranked at the top and NG5007 b2 XF ranked at the bottom for root morphological traits(total and fine root length, surface area,and volume) and root weight. PHY 499 WRF was also one of the best biomass producers and had high water use efficiency. PHY 444 WRF, PHY 430 W3 FE, and PD-1 were the other best genotypes in terms of root traits and water use efficiency. All genotypes had higher values for root traits and water use efficiency under hardpan conditions. This trend indicates a horizontal proliferation of root systems when they incur a stress imposed by a hardpan. The genotypic differences identified in this research for root traits and water use efficiency would be valuable for selecting genotypes for cotton breeding programs.

关键词： Cotton Root traits Water use efficiency Hardpan Genetic variability

Real-world treatment patterns of gastrointestinal neuroendocrine tumors: A claims database analysis

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2017年第33期23卷 6128-6136页

作者： Al b benson III michael S broder beilei Cai Eunice Chang Maureen P Neary Elya Papoyan Northwestern University Partnership for Health Analytic Research Novartis Pharmaceuticals

AIM To describe real-world treatment patterns of gastrointestinal neuroendocrine tumors(GI NET).METHODS In this retrospective cohort study,we used 2009-2014 data from 2 United States commercial claims databases to examine newly pharmacologically treated patients using tabular and graphical techniques. Treatments included somatostatin analogues(SSA),cytotoxic chemotherapy(CC),targeted therapy(TT),interferon(IF) and combinations. We identified patients at least 18 years of age,with ≥ 1 inpatient or ≥ 2 outpatient claims for GI NET who initiated pharmacologic treatment from 7/1/09-6/30/14. A 6 mo clean period prior to first treatment ensured patients were newly treated. Patients were followed until end of enrollment or the study end date,whichever was *** We identified 2258 newly treated GI NET patients: mean(SD) age was 55.6 years(SD = 9.7),47.2% of the patients were between 55 and 64 years,and 48.8% were female. All regions of the United States were represented. 59.6% started first-line therapy with SSA monotherapy(964 with octreotide LAR,380 with octreotide SA,and 1 with lanreotide),33.3% CC,3.6% TT,and 0.5% IF. The remainder received combinations. Mean follow up was 576 d. Overall mean first-line therapy duration was 361 d(449 d for SSA,215 for CC,267 for TT). 58.9% of patients had no pharmacological treatment beyond first line. The most common secondline was combination therapy with SSA. In graphical pattern analysis,there was no clear pattern visible after first line *** In this study,60% of patients initiated treatment with SSA alone or in combination. The relatively long time to discontinuation suggests possible sustained effectiveness and tolerability.

关键词： Gastrointestinal neuroendocrine tumors Treatment patterns Insurance claims Somatostatin analogue Targeted therapy Chemotherapy

Efficacy and safety of single-bolus tenecteplase compared with front-loaded alteplase in Chinese patients with acute myocardial infarction

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Geriatric Cardiology 2007年第3期4卷 142-143页

作者： Yuri b. Pride C. michael Gibson Department of Medicine Beth Israel Deaconess Medical CenterHarvard Medical SchoolBostonMAUSA Division of Cardiology Department of MedicineBeth Israel Deaconess Medical CenterHarvard Medical SchoolBostonMAUSA

　　Following ST-segment elevation myocardial infarction(STEMI), early and complete epicardial reperfusion is associated with improved survival.……

关键词： STEMI Efficacy and safety of single-bolus tenecteplase compared with front-loaded alteplase in Chinese patients with acute myocardial infarction