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高度纯化的2a型福氏志贺菌侵染素复合物疫苗的免疫原性和效力

Advances in Microbiology（微生物学） 2020年第11期

作者： Balbina J. Plotkin Ira M. Sigar Amber kaminski Jessica Kreamer Brent Ito Joan Kacmar

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国际生物制品学杂志 2009年第4期32卷 219-219页

作者： Turbyfill KR kaminski RW 0aks EV

痢疾亚单位疫苗的研制需要确认保护性抗原，并要以一定的方式传递这些抗原，从而使抗原能诱导与自然感染相同的免疫应答。美国Walter Reed陆军研究所Turbyfill等研制的志贺菌侵染素复合物（Invaplex）疫苗为有毒力志贺菌的离子交换纯化... 详细信息

痢疾亚单位疫苗的研制需要确认保护性抗原，并要以一定的方式传递这些抗原，从而使抗原能诱导与自然感染相同的免疫应答。美国Walter Reed陆军研究所Turbyfill等研制的志贺菌侵染素复合物（Invaplex）疫苗为有毒力志贺菌的离子交换纯化提取物，由脂多糖（LPS）和一些蛋白质组成，包括侵染素IpaB和IpaC。此项研究旨在检测这一疫苗的免疫原性和效力。

关键词：亚单位疫苗福氏志贺菌免疫原性复合物侵染纯化保护性抗原 a型

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法国人群的引产调查:COCON研究结果

世界核心医学期刊文摘（妇产科学分册） 2005年第6期1卷 58-58页

作者： Lelong N. Moreau C. kaminski M. 杨晓梅 IN-SERM U149- IFR69 16 avenue Paul- Vaillant- Couturier 94807 Villejuif Cedex France

Objective. The aim of this article is to describe conditions of abortions practices in France. Materials and methods. The study was based on the COCON survey. This survey was carried out among a representative sample of 2863 women aged 18 to 44 living in metropolitan France. Women were interviewed by telephone. The analysis was performed among a sub- sample of 320 women who had had an abortion between 1996 and 2000. Results were compared with those of the national notification of induced abortions. Results. Altogether, the way in which abortions were carried out was appropriate, but differences were observed according to the type of hospital: access to care was easier in the private sector; however a pre- abortion interview was less often carried out and a post- abortion interview less often proposed in the private sector. Besides, in both sectors, women were rarely allowed to choose the abortion technique, or the type of anesthesia in the case of a surgical abortion. Conclusion. The COCON study is the first population based survey describing the characteristics of care regarding voluntary abortion. It shows the persistence of differences in practices between the public and the private sectors.

关键词：引产方法 COCON 私立医院公立医院医患交流产时描述法

美国重症肌无力基金会关于重症肌无力临床试验的建议

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中国神经免疫学和神经病学杂志 2013年第1期20卷 74-74页

作者： Benatar M Sanders DB Burns TM Cutter GR Guptill JT Baggi F kaminski HJ Mantegazza R Meriggioli MN Quan J Wolfe GI 李海峰(摘译) 高翔(摘译) 不详青岛大学医学院附属医院神经内科

由美国重症肌无力基金会（MGFA）的医学科学建议委员会（MSAB）组成工作组，于2010年在美国和2011年在意大利召开专家共识会议讨论重症肌无力（MG）临床试验的问题，与会代表包括来自美国和欧洲的神经科医生、统计学家、企业界代表、MG... 详细信息

由美国重症肌无力基金会（MGFA）的医学科学建议委员会（MSAB）组成工作组，于2010年在美国和2011年在意大利召开专家共识会议讨论重症肌无力（MG）临床试验的问题，与会代表包括来自美国和欧洲的神经科医生、统计学家、企业界代表、MG患者以及MGFA和欧洲重症肌无力协会的平民代表。

关键词：重症肌无力临床试验基金会美国科学建议工作组委员会意大利

发生在1例重度Moya Moya患儿的匐行性穿通性弹性纤维性假黄瘤

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世界核心医学期刊文摘（皮肤病学分册） 2005年第11期1卷 41-41页

作者： Meyer S. Zanardo L. kaminski W.E. T. Vogt 刘艳 Department of Dermatology University of Regensburg D-93042 Regensburg Germany

A 2-year-old girl with Moya Moya disease who had relapsing cerebrovascular strokes presented with loose skin folds, ‘chicken’skin appearance and perforating elastosis serpiginosalike lesions in the genitocrural region. Histologically, calcified material perforating the epidermis and adjacent short curled and mineralized elastic fibres suggested a variant of pseudoxanthoma elasticum (PXE). As PXE is known to be caused by various mutations in the transmembrane transporter ABCC6 gene, we hypothesized that a novel ABCC6 mutation may underlie this unique combination of PXE and elastopathic vascular damage. Therefore, the complete ABCC6 coding region of the patient and her parents was screened for genetic alterations. No bona fide disease-causing mutation of ABCC6 could be found in the child and in her parents. However, two novel allelic amino acid substitutions (Arg1273Lys and Glu1293Lys; exon 27) were found in the girl and her father, localized in close proximity to the region that codes for the functionally critical second nucleotide-binding fold of ABCC6. Although a causal involvement of these amino acid substitutions could not be proven based on this study, both heterozygote substitutions may possibly have interacted with other undetected recessive maternal ABCC6 changes in the child. To the best of our knowledge, this is the first report of an association between early-onset PXE and severe Moya Moya syndrome possibly related to ABCC6 changes.

关键词： Moya Moya 弹性假黄瘤钙化物质皮肤松弛生殖器部位纤维变性跨膜转运蛋白编码区血管损害纤维断裂

β-delayed Multi-particle Emission From 31^Ar

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原子核物理评论 2016年第2期33卷 221-224页

作者： A. A. Ciemny C. Mazzocchi W. Dominik Z. Janas M. Pfutzner M. Pomorski L. Acosta S. Baraeva E. Casarejos J. Duenas-Daz V. Dunin J. M. Espino A. Estrade F. Farinon A. Fomichev H. Geissel A. Gorshkov G. kaminski O. Kiselev R. Knobel S. Krupko M. Kuich Yu. A. Litvinov G. Marquinez-Duran I. Martel I. Mukha C. Nociforo A. K. Orduz S. Pietri A. Prochazka A. M. Sanchez-Benitez H. Simon B. Sitar R. Slepnev M. Stanoiu P. Strmen I. Szarka M. Takechi Y. Tanaka H. Weick J. S. Winfield Faculty of Physics University of Warsaw 02-093 Warszawa Poland GSI Helmholtzzentrum für Schwerionenforschung 64291 Darmstadt Germany INFN Laboratori Nazionali del Sud Via S. Sofia Catania Italy Instituto de Fisica Universidad Nacional Autonoma de Mexico Mexico D. F. 01000 Mexico Joint Institute for Nuclear Research 141980 Dubna Russia University of Vigo 36310 Vigo Spain Department of Applied Physics University of Huelva 21071 Huelva Spain University of Seville 41012 Seville Spain University of Edinburgh EH1 1HT Edinburgh United Kingdom Institute of Nuclear Physics PAN 31-342 Krakow Poland Joint Institute for Nuclear Research 141980 Dubna Moscow Region Russia Faculty of Physics Warsaw University of Technology 00-662 Warszawa Poland Centro de Fisica Nuclear da Universidade de Lisboa 1649-003 Lisboa Portugal Faculty of Mathematics and Physics Comenius University 84248 Bratislava Slovakia IFIN-HH Post Office Box MG-6 Bucharest Romania University of Tokyo Japan

The β^+ decay of ^(31)Ar was investigated in an experiment at the GSI-FRS *** ions of interest have been produced in the fragmentation of a ^(36)Ar beam at 880 Me V/nucleon and implanted in a time projection chamber with optical readout. In addition to β-delayed one and two proton emission, for the first time the emission of β-delayed 3 protons has been observed. The branching ratio for this decay mode is found to be(0.07 ± 0.02)%.

关键词： 31Ar beta-delayed protons OTPC

用抗独特型单克隆抗体治疗具有同型转换变异抗体的小鼠B细胞淋巴瘤

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细胞与分子免疫学杂志 1987年第4期 103-103页

作者： M.S kaminski,K.Kitamura,D.G.Maloney,M.J.Campbell,R.Levy,张明杰 12]M 15]M Stanford University Medical Center Currently at University of Michigan Medical Center 3]M 6]M 9]M Ann Arbor Stanford University Medical Center Currently at University of Michigan Medical Center Ann Arbor Stanford University Medical Center Currently at University of Michigan Medical Center Ann Arbor Stanford University Medical Center Currently at University of Michigan Medical Center Ann Arbor Stanford University Medical Center Currently at University of Michigan Medical Center Ann Arbor

在以前的研究中,应用同系抗独特型单克隆抗体对38C13鼠B细胞淋巴瘤进行了体内治疗,果结表明,IgG2a同型抗体抑制C3H小鼠肿瘤生长的作用（70％长期存活）较两种IgG1型抗体（10％和20％存活）以及另一种IgG1型抗体（0％存活更为有效）。人... 详细信息

在以前的研究中,应用同系抗独特型单克隆抗体对38C13鼠B细胞淋巴瘤进行了体内治疗,果结表明,IgG2a同型抗体抑制C3H小鼠肿瘤生长的作用（70％长期存活）较两种IgG1型抗体（10％和20％存活）以及另一种IgG1型抗体（0％存活更为有效）。人为了单独测定抗体型别在这些抗肿瘤作用的地位,应用有限稀释法从分泌低效力IgG1和IgG2抗体的杂交瘤培养物中分离两族同型变异体。一族由IgG1（亲）、lgG2a和IgG2b组成,另一族由IgG2b

关键词：抗体同型 IgG 细胞淋巴瘤

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兔后弹力层前人造角膜生物反应

美国医学会眼科杂志（中文版） 2005年第3期17卷 177-177页

作者： Josef Stoiber Viviana Fernandez Stephan kaminski Peggy D. Lamar Sander Dubovy Eduardo Alfonso Jean-Marie Parel 陆遥（译）

目的：评估一种新型的非穿透角膜修复术（后弹力层前人造角膜）在兔模型上的生物相容性。

关键词：人造角膜后弹力层兔模型生物反应生物相容性修复术非穿透