The recent innovation of a rectangular tunnel boring machine(TBM),and its use in the Hongzhuan Road tunnel underpass by the China Railway Engineering Group(CREG),has revitalized shallow depth soft soil *** paper prese...
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The recent innovation of a rectangular tunnel boring machine(TBM),and its use in the Hongzhuan Road tunnel underpass by the China Railway Engineering Group(CREG),has revitalized shallow depth soft soil *** paper presents the findings of a numerical study using PLAXIS to determine the surface settlements and moments produced in tunnel linings for circular and rectangular twin *** effects of the relative positions of twin tunnels,critical distances,volume losses,depths of burial,and tunnel sizes for both circular and rectangular tunnels are the key parameters of this *** results indicate that rectangular tunnels are suitable for shallow depths in weak ground as they have lesser settlement compared with circular *** is crucial for tunneling beneath important structures such as railway lines and existing ***,the maximum bending moment produced in the rectangular tunnel lining is higher than that for circular *** use of rectangular TBMs is an unconventional method in modern day tunneling;however,the analysis in this project recommends that tunnel industry engineers consider this method for shallow depth weak ground tunneling.
Cytomegalovirus(CMV)infection of the gastrointestinal (GI)tract has been reported in both immunocompetent and,more frequently,in immunocompromised *** describe a case of a 19-year-old male who developed CMV infection ...
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Cytomegalovirus(CMV)infection of the gastrointestinal (GI)tract has been reported in both immunocompetent and,more frequently,in immunocompromised *** describe a case of a 19-year-old male who developed CMV infection of the terminal ileum while receiving immunosuppression for lupus nephritis. This was a distinctly unusual site of infection which clinically mimicked Crohn's *** note that reports of terminal ileal CMV infection have been infrequent. Despite a complicated hospital course,ganciclovir therapy was effective in resolving his symptoms and normalizing his ileal *** report highlights the importance of accurate histological diagnosis and clinical follow-up of lupus patients with GI symptoms undergoing intense immunosuppression.
AIM:To study if impaired renal function is associated with increased risk of peri-infarct heart failure (HF) in patients with preserved ejection fraction (EF).METHODS:Patients with occluded infarct-related arteries (I...
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AIM:To study if impaired renal function is associated with increased risk of peri-infarct heart failure (HF) in patients with preserved ejection fraction (EF).METHODS:Patients with occluded infarct-related arteries (IRAs) between 1 to 28 d after myocardial infarction (MI) were grouped into chronic kidney disease (CKD) stages based on estimated glomerular filtration rate (eGFR).Rates of early post-MI HF were compared among eGFR *** regression was used to explore independent predictors of ***:Reduced eGFR was present in 71.1% of 2160 patients,with significant renal impairment (eGFR < 60 mL/min every 1.73 m2) in 14.8%.The prevalence of HF was higher with worsening renal function:15.5%,17.8% and 29.4% in patients with CKD stages 1,2 and 3 or 4,respectively (P < 0.0001),despite a small absolute difference in mean EF across eGFR groups:48.2 ± 10.0,47.9 ± 11.3 and 46.2 ± 12.1,respectively (P=0.02).The prevalence of HF was again higher with worsening renal function among patients with preserved EF:10.1%,13.6% and 23.6% (P < 0.0001),but this relationship was not significant among patients with depressed EF:27.1%,26.2% and 37.9% (P= 0.071).Moreover,eGFR was an independent correlate of HF in patients with preserved EF (P=0.003) but not in patients with depressed EF (P=0.181).CONCLUSION:A significant proportion of post-MI patients with occluded IRAs have impaired renal *** renal function was associated with an increased rate of early post-MI HF,the association being strongest in patients with preserved *** findings have implications for management of peri-infarct HF.
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