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Admission Motor Strength Grade Predicts Mortality in Patients with Acute Ischemic Stroke Undergoing Mechanical Thrombectomy

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Neuroscience & Medicine 2013年第1期4卷 1-6页

作者： Vishnumurthy Shushrutha Hedna Aakash N. Bodhit Saeed Ansari Adam D falchook Latha G. Stead Sharathchandra Bidari Brian L Hoh Kenneth M Heilman michael f waters Department of Emergency Medicine University of Florida Gainesville USA Department of Neurology University of Florida Gainesville USA Department of Neuroradiology University of Florida Gainesville USA Department of Neurosciences University of Florida Gainesville USA. Department of Neurosurgery University of Florida Gainesville USA

Background: The mortality due to mechanical thrombectomy (MT) in the acute treatment of intracranial arterial occlu- sions can be up to 45%. The SWIfT (Solitaire fR with the Intention for Thrombectomy) and Multi MERCI (mechani- cal embolus removal in cerebral ischemia) trials have evaluated the safety and efficacy of MT. It may be important to determine pre-procedural factors that help predict post-intervention prognosis. We sought to determine if admission medical research council (MRC) motor strength grade along with other factors can be used as predictor of mortality after MT for acute ischemic stroke. Methods: Retrospective analysis of stroke database assessing outcomes in all 62 patients who underwent MT as an intervention for acute ischemic stroke, with or without concurrent intravenous thrombolysis was done. five baseline variables were included in univariate and multivariate analyses to define the in- dependent predictors of mortality during current hospitalization. The medical research council (MRC) motor grade (0 - 5);modified collateral flow (CS) grading (0 - 3);age;acute and chronic co-morbidities were used as the baseline vari- ables. If motor strength grade were different in upper and lower extremities, then the lower grade was used. Age was analyzed independently as well as dichotomized using 80 as cut-off value. Relevant stroke related acute and chronic co-morbidities were given 1 point each and mean calculated. Results: In the univariate analysis, low (0 - 1) motor strength grade (OR, 0.11;95% CI, 0.021 - 0.33;p = 0.001) and age (OR, 1.06;95% CI, 1.02 - 1.12;p = 0.011) was sig- nificantly associated with mortality. The presence of collateral flow, acute and chronic co-morbidities were not signifi- cantly associated with mortality. In the multivariate analysis, motor grade retained its statistical significance for morta- lity (OR, 0.09;95% CI, 0.01 - 0.32;p = 0.003) along with chronic co-morbidity (OR, 1.52;95% CI 1.05 - 2.43;

关键词： Motor Grade Collaterals Ischemic Stroke Endovascular Intervention Outcome after Stroke Mortality after Stroke Acute Stroke Endovascular Treatment Mechanical Thrombectomy

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Experimental Study for Effect of Multi-Site Spark Ignition on Dedicated Hybrid Engine Performance under High Dilution Condition

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Journal of Thermal Science 2025年第1期 254-267页

作者： YAN Bowen waters Benjamin HAINES Andrew MCGHEE Mike HU Tiegang DENG Wei PU Yongxian MA Tianyu Powertrain Engineering R&D Center Chongqing Changan Automobile Co.Ltd. Changan UK R&D Centre Limited

In this study,a triple spark ignition scheme was first designed on a three-cylinder 1.5-L dedicated hybrid engine（DHE）.On this basis,the effect of different ignition modes on engine combustion and emission characteristics was studied,especially under high dilution *** results tested at 2000 r/min and 0.8 MPa BMEP（brake mean effective pressure） show that with highly increased in-cylinder flow intensity,using only passive prechamber（PPC） has a lower lean limit than that with single central spark plug（CSP）,thereby leading to slightly higher minimum fuel consumption and nitrogen oxides（NOx） *** side spark plugs（SSP）based on PPC can result in improved capability of lean limit extension and engine performance than ***,the improvement level is lower than that with triple spark plugs（TSP）.As the excess air ratio λincreases,the advantage of PPC and PPC with SSP in improving the combustion phasing compared with CSP gradually ***,the increasing tendency of their ignition delay and combustion duration is more *** added SSP based on PPC can effectively shorten the ignition delay of leaner mixture,but the combustion duration can be only slightly *** a result,under extremely lean condition,the advantage of PPC and PPC with SSP in terms of combustion characteristics over CSP becomes much *** contrast,the TSP ignition can achieve much shorter ignition delay and combustion duration simultaneously under this *** to the highest available dilution level,the TSP ignition achieves the lowest raw ***,it can also reduce the raw carbon monoxide（CO） and hydrocarbons（HC） emissions compared to CSP due to a more thorough combustion of the end gas *** on the excellent performance of TSP,the highest engine brake thermal efficiency（BTE） was further *** results show that with normal RON 92 fuel,the engine finally achieved 43.69% and 45.02% BTE under stochiometric mode with exhaust

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Spoilt for Choice:New Options for Inhibitors of Strigolactone Signaling

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Molecular Plant 2019年第1期12卷 21-23页

作者： Mark T.waters School of Molecular Sciences The University of Western AustraliaPerth WA 6009Australia

Endogenously synthesized plant hormones direct the ordered growth of tissues,organs,and the overall plant body plan, thereby integrating external information with internal metabolism. Because plant hormones can have such dramatic and systemic effects on plant morphology,hormone activity has been a target of selective breeding for desirable plant traits,whether consciously or otherwise.

关键词： growth plan

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flotation behavior and electronic simulations of rare earth minerals in the presence of dolomite supernatant using sodium oleate collector

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Journal of Rare Earths 2019年第1期37卷 101-112,M0005页

作者： E.R.L.Espiritu G.R.da Silva D.Azizi f.Larachi K.E.waters Department of Mining and Materials Engineering McGill University Department of Chemical Engineering Université Laval

Common rare earth(RE) minerals, such as bastnasite and monazite, may be formed in deposits associated with carbonate gangue, such as calcite and dolomite. Sodium oleate is a widely used collector for the flotation of both RE and gangue minerals, which might, therefore, be an inefficient process due to the lack of selectivity of this collector. Since these minerals are also sparingly soluble in solution, they could release their constituent ions into the solution, which could affect the floatability of other minerals. In this study, the interactions of sodium oleate with bastnasite and monazite in the presence of dissolved dolomite species have been investigated. Microflotation tests were carried out to explore the effects of these dissolved species on the floatability of the RE minerals. Zeta potential measurements and XPS characterization were carried out to understand how the species affect the collector adsorption. To complement these characterizations, density functional theory(DfT) simulations were conducted to investigate the collector-mineral and collector-adsorbed species(on the mineral surface) *** results show that collector-dolomite interaction energy is greater than that of collector-adsorbed species, but lower than collector-monazite interaction energy, explaining the decrease in the minerals' recovery upon exposure to the dissolved mineral species. It is also shown that oleate ions(OI^-) have the strongest interaction with the minerals compared to other oleate species such as acid soap(HOI_2^-) and oleate dimer(OI_2^(2-)). The behavior(strength and selectivity) of sodium oleate towards RE minerals and dolomite, as compared to other RE mineral collectors(such as aromatic hydroxamate), is attributed mainly to the collector's and the minerals' structure. The long hydrocarbon chain of sodium oleate which imparts hydrophobic characteristic to the minerals, makes it stronger collector than ***, sodium oleate(with linear str

关键词： Rare earth minerals Bastnsite Monazite Dolomite Sodium oleate DfT simulation

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Sensitivity Analysis and Computations of the Time RelaxationModel

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Advances in Applied Mathematics and Mechanics 2015年第1期7卷 89-115页

作者： Monika Neda fran Pahlevani Jiajia waters Department of Mathematics University of NevadaLas VegasNV 89154USA Department ofMathematics Penn State University-Abington CollegePA 19001USA

This paper presents a numerical study of the sensitivity of a fluid model known as time relaxation model with respect to variations of the time relaxation coefficient *** sensitivity analysis of this model is utilized by the sensitivity equation method and uses the finite element method along with Crank Nicolson method in the fully discretization of the partial differential *** present a test case in support of the sensitivity convergence and also provide a numerical comparison between two different strategies of computing the sensitivity,sensitivity equation method and forward finite differences.

关键词： Sensitivity analysis time relaxation model Navier-Stokes equations finite element method.

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Physicochemical aspects of allanite flotation

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Journal of Rare Earths 2014年第5期32卷 476-486页

作者： Adam Jordens Chris Marion Olga Kuzmina Kristian E.waters Department of Mining and Materials Engineering McGill University

This paper investigated the physicochemical properties of allanite, a RE-silicate, by measuring zeta potential in the absence and presence of three different flotation collectors （benzohydroxamic acid, sodium oleate and dodecylamine）. This data was then verified by microflotation experiments and with bubble-particle attachment pictures. The investigated properties of allanite were com- pared to those of quartz, a common gangue mineral in many RE deposits. The results of this work indicated that only dodecylamine was able to achieve a selective separation of allanite and quartz. This was accomplished by lowering the dodecylamine dosage so that only quartz was recovered by microflotation.

关键词： allanite flotation surface chemistry zeta potential bubble-particle attachment rare earths

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KAI2-and MAX2-Mediated Responses to Karrikins and Strigolactones Are Largely Independent of HY5 in Arabidopsis Seedlings

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Molecular Plant 2013年第1期6卷 63-75页

作者： Mark T. waters Steven M. Smitht Plant Energy Biology University of Western Australia Crawley Western Australia 6009 Australia School of Chemistry and Biochemistry University of Western Australia Crawley Western Australia 6009 Australia

Karrikins are butenolide compounds released from burning vegetation that stimulate seed germination and enhance seedling photomorphogenesis. Strigolactones are structurally similar plant hormones that regulate shoot and root development, and promote the germination of parasitic weed seeds. In Arabidopsis, the f-box protein MAX2 is required for responses to karrikins and strigolactones, and the a/~ hydrolase KAI2 is necessary for responses to karrikins. Both MAX2 and KAI2 are essential for normal light-dependent seedling development. The bZIP transcription factor HY5 acts downstream of multiple photoreceptors and promotes photomorphogenesis, but its relationship with MAX2 and KAI2 in terms of seedling development and responses to karrikins and strigolactones is poorly defined. Here, we dem- onstrate that HY5 action is genetically separable from that of MAX2 and KAI2. While by5 mutants have weak hypoco- tyl elongation responses to karrikins and the artificial strigolactone GR24, they have normal transcriptional responses, suggesting that HY5 is not involved in perception or action of karrikins or strigolactones. furthermore, we show that overexpression of KAI2 is sufficient to enhance responses to both karrikins and GR24 in wild-type seedlings, and that KAI2 overexpression partially suppresses the hy5 long hypocotyl phenotype. These results suggest that KAI2 and MAX2 define a regulatory pathway that largely operates independently of HY5 to mediate seedling responses to abiotic signals such as smoke and light.

关键词： smoke karrikin strigolactone KAI2 HY5 photomorphogenesis.

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waters ACQUITY UPLC^(TM)介绍

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环境化学 2004年第5期23卷 605-611页

作者： waters公司北京实验室 waters公司北京实验室北京市100027

当年 ( 1 996年 )waters公司推出AllianceHPLC时 ,主要的目标是 :提高液相色谱仪的“精度” .针对当时多数公司认为HPLC技术已经发展到头了 ,没有更高性能的需求 ,因此 ,HPLC的目标应该是降低成本 ,走向更低的价格 ,以获得更广泛的应用... 详细信息

当年 ( 1 996年 )waters公司推出AllianceHPLC时 ,主要的目标是 :提高液相色谱仪的“精度” .针对当时多数公司认为HPLC技术已经发展到头了 ,没有更高性能的需求 ,因此 ,HPLC的目标应该是降低成本 ,走向更低的价格 ,以获得更广泛的应用这样一个观念 ,waters提出的概念及口号是

关键词： HPLC TM 益处促进要求需求目标园地应用降低成本

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多环芳烃的HPLC分析——充分发挥waters Alliance HPLC系统的先进功能

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环境化学 2001年第4期20卷 409-410页

作者： waters公司北京实验室 waters公司北京实验室北京100005

多环芳烃是倍受关注的环境污染物．不同样品基质中多环芳烃的样品处理和ＨＰＬＣ分析方法在ＥＰＡ标准方法中都有明确的描述(见表１)．

关键词：环境监测多环芳烃 HPLC分析环境污染物样品 waters Alliance HPLC系统

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利用waters Oasis MAX小柱提取/HPLC分析酸性农药残留物质

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环境化学 2001年第1期20卷 93-94页

作者： waters公司北京实验室 waters公司北京实验室

Oasis HLB吸附剂是waters公司研究开发的用于样品前处理的固相提取产品，可以提取各种不同样品基质中的酸性、中性及碱性物质.Oasis MAX是以Oasis HLB填料为基础合成的新型提取吸附填料，具有疏水作用及阴离子交换两种不同的提取机理.MA... 详细信息

Oasis HLB吸附剂是waters公司研究开发的用于样品前处理的固相提取产品，可以提取各种不同样品基质中的酸性、中性及碱性物质.Oasis MAX是以Oasis HLB填料为基础合成的新型提取吸附填料，具有疏水作用及阴离子交换两种不同的提取机理.MAX填料对酸性物质有其独特的选择性，可用于酸性物质与中性及碱性物质的分别提取. 使用Oasis MAX填料可以实现以往C18填料无法完成的酸性物质提取.草甘膦及其主要代谢产物氨甲基膦酸(AMPA)的提取便是一例(见表1).此类强极性物质无法用反相C18填料提取并进行HPLC分析，但利用Oasis MAX独特的阴离子交换能力可对之进行提取，用waters Ion Exclusion(离子排斥柱)进行HPLC分析(见图1).

关键词：酸性农药残留物质 HPLC MAX填料液相色谱分析

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