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In vivo optical quality of posterior-chamber phakic implantable collamer lenses with a central port

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Eye and Vision 2021年第5期8卷 295-302页

作者： Robert Montés-micó Francisco Pastor-Pascual Enrique Artiaga-Elordi Ramón Ruiz-Mesa Pedro Tañá-Rivero Optics and Optometry&Vision Sciences Department University of Valenciac/o Dr Moliner 5046100 ValenciaSpain Oftalvist Clinic ValenciaSpain

Background:The aim of this review is to summarize the optical quality results in patients following the implantation of the V4c implantable collamer lens with a central port(ICL,STAAR Surgical Inc.).Main text:A literature search in several databases was carried out to identify those publications,both prospective,retrospective and/or comparative with other refractive surgery procedures,reporting optical outcomes of patients who were implanted with the V4c ICL model.A total of 17 clinical studies published between 2012 and 2021 were included in this review.A detailed analysis of the available data was performed including number of eyes,follow-up and preoperative spherical ***,the review focused on several optical parameters including higher-order aberrations(hOAs),modulation transfer function(MTF)cut-off frequency and Strehl *** review encompassed a total of 817 eyes measured using different optical devices based on hartmann-Shack,retinal image quality measurement and ray-tracing technologies at different ***:The outcomes found in this review lead us to conclude that the ICL V4c model provides good optical quality,by means of different metrics,when implanted.

关键词： Implantable collamer lens Phakic Optical quality higher order aberrations Modulation transfer function

BRITTLE-DUCTILE TRANSITION OF ANNEALEMBRITTLED Fe_(75)Si_(10)B_(15)METALLIC GLASS

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Acta Metallurgica Sinica(English Letters) 1992年第10期5卷 292-299页

作者： DAVIES h A School of Materials University of Sheffield.U.K.

Studies were made of the effect of mechanical pulverization on relaxation,crystallization and brittle-ductile transition of the anneal-embrittled Fe_(75)Si_(10)B_(15) metallic glass rib- *** show that the Curie temperature,T_C,decreases and the total enthalpy of relaxation increases gradually with variation of pulverized *** traces reveal an extra exothermic peak,T_X_1,and a distinct glass transition endothermic peak,T_g_1,with increasing pulverized time,T_C,T_X_1,and T_g_1 decrease simultaneously,and the exother- mic peak area corresponding to T_X_1 increases *** surface slip-steps of flaky particles and their corresponding shear are produced by pulverizing the pre-embrittled amorphous *** lost ductility of the glass may restore during annealing.

关键词： mechanical pulverization Fe_(75)Si_(10)B_(15) metallic glass shear band

Time-kill kinetics and biocidal effect of Euclea crispa leaf extracts against microbial membrane

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Asian Pacific Journal of Tropical Medicine 2017年第4期10卷 370-377页

作者： Kazeem Adekunle Alayande Carolina(h) Pohl Anofi Omotayo Tom Ashafa Phytomedicine and Phytopharmacology Research Group Department of Plant ScienesUniversity of the Free State Depatment of microbial Biochemical & Food BiotechnologyUniversity of the Free State

Objective:To evaluate antimicrobial potential of the fractions partitioned from Enclea crispa leaf extract and determination of their impact on cell membrane ***:Antimicrobial potentials were evaluated via susceptibility test,determination of minimum inhibitory concentrations(mics) and time-kill kinetics of the potent *** of membrane disruption was determined by the amount of proteins and nucleotides released from within the cells and SEM images of the membrane after 120 min of ***:The largest inhibition zone(25.5±0.50 mm) was obtained by ethylacetate fraction against Aeromonas hydrophilla at 10 mg/*** lowest mic(0.16 mg/mL) was exhibited by n-butanol and ethylacetate fractions against test bacteria while all fractions exhibited mic values between 0.31 and 1.25 mg/mL against susceptible yeast.n-Butanol fraction achieved absolute mortality against Bacillus pumulis(***) and Klebsiella pneumoniae(***) after 90 and 120 min contact time respectively at 1 *** mortality also achieved by n-hexane fraction against *** and K pneumoniae after 90 and 120 min respectively at 2 *** fraction achieved absolute mortality against both bacteria after 120 min at 2 mic.n-hexane fraction achieved total mortality against Candida albicans after 120 min at 1 *** amount of proteins(0.566 Mg/mL) was released from *** by n-butanol fraction at 2 mic after 120 min of treatment while the maximum amount of nucleotides released(4.575 ug) was from *** by n-hexane fraction under similar ***:This study suggests the leaf of Euclea crispa a source of bioactive compound with membrane attack as one of the mechanisms of its biocidal action.

关键词： Pathogens MlCs Protein leakage Nucleotides leakage SEM

Effect of even and odd-order aberrations on the accommodation response

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International Journal of Ophthalmology(English edition) 2017年第6期10卷 955-960页

作者： Aikaterini I.Moulakaki Antonio J.Del águila-Carrasco José J.Esteve-Taboada Robert Montés-micó Department of Optics and Optometry and Vision Sciences University of Valencia C/Dr. Moliner 50 Burjassot 46100 Valencia Spain

AIM： To investigate the potential effect that odd and even-order monochromatic aberrations may have on the accommodation response of the human eye. METhODS： Eight healthy subjects with astigmatism below 1 D, best corrected visual acuity 20/20 or better and normal findings in an ophthalmic examination were enrolled. An adaptive optics system was used in order to measure the accommodation response of the subjects＇ eyes under different conditions： with the natural aber- rations being present, and with the odd and even-order aberrations being corrected. Three measurements of accommodation response were monocularly acquired at accommodation demands ranging from 0 to 4 D （0.5 D step）. RESULTS： The accommodative lag was greater for the accommodate demands of 1.5, 3, 3.5 and 4 D for the condition in which the even-order aberrations were corrected, in comparison to that obtained for the natural aberrations and corrected odd-order aberrations for the same accommodation demands. No statistically significant differences were found between the accommodation responses under the three conditions. CONCLUSION： The odd and even-order aberrations are not helping the visual system to accommodate, because their partial correction do not affect the accommodation performance.

关键词： accommodation response monochromaticaberrations adaptive optics

Angle-to-angle and spur-to-spur distance analysis with high-resolution optical coherence tomography

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Eye and Vision 2020年第1期7卷 399-411页

作者： Robert Montés-micó Pedro Tañá-Rivero Salvador Aguilar-Córcoles María Ruiz-Santos María Dolores Rodríguez-Carrillo Ramón Ruiz-Mesa Oftalvist Alicante and Jerez de la FronteraAlicanteSpain University of Valencia ValenciaSpain

Background:To measure angle-to-angle(ATA)and spur-to-spur(STS)distances along six meridians using highresolution swept-source optical coherence tomography(SS-OCT)and to compare those values with horizontal white-to-white(WTW)***:68 eyes from 68 patients were quantitatively assessed with the Anterion SS-OCT(heidelberg Engineering,heidelberg,Germany).ATA and STS distances were measured with the SS-OCT’s B-Scan in six cross-sectional images corresponding to the vertical(6-12 o’clock),1-7 o’clock,2-8 o’clock,horizontal(3-9 o’clock),4-10 o’clock and 5-11 o’clock *** was measured horizontally with the device’s infrared camera.A Pearson correlation analysis was carried out to compare ATA and STS distances with ***:The largest values were found for the vertical meridian and the shortest for the 2-8 o’clock meridian,both for ATA and STS *** statistically significant differences were found between WTW,ATA and STS along the horizontal meridian(p>0.1).however,ATA and STS showed statistically significant differences elsewhere,except for the horizontal and the 2-8 o’clock meridians(p>0.05).Moreover,we found that ATA and STS varied significantly depending on the meridian being assessed,except for ATA at 4-10 versus 3-9 o’clock and for STS at 4-10 versus 3-9 o’clock and at 3-9 versus 2-8 o’clock(p>0.1).R^(2) values ranged from 0.49 to 0.75 for ATA and STS at the different meridians,showing the best correlation at 3-9 o’clock meridian(0.64 and 0.75,respectively)and the worst at 6-12 o’clock meridian(R^(2)=0.49 for both ATA and STS).Conclusions:ATA and STS distances vary radially,thus showing that the anterior chamber is vertically ***,it is advisable to measure these two distances along the meridian to be used.

关键词： Angle-to-angle Spur-to-spur White-to-white Optical coherence tomography Swept-source Fourier domain

Device interchangeability on anterior chamber depth and white-to-white measurements: a thorough literature review

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International Journal of Ophthalmology(English edition) 2016年第7期9卷 1057-1065页

作者： Alberto Domínguez-Vicent Cari Pérez-Vives Teresa Ferrer-Blasco Santiago García-Lázaro Robert Montés-micó Optometry Research Group (GIO) Department of Optics and Optometry and Visual Science University of Valencia

We have reviewed a set of recently published studies that compared the anterior chamber depth（ACD） and/or white-to-white（WTW） distance obtained by means of different measuring *** some of those studies reached contradictory conclusions regarding device interchangeability,this review was carried out in attempting to clarify which clinical devices can or cannot be considered as interchangeable in clinical practice to measure ACD and/or WTW distance,among these devices：A-scan,ultrasound biomicroscopy,Orbscan and Orbscan Ⅱ（Bausch＆Lomb Surgical Inc.,San Dimas,California,USA）,Pentacam and Pentacam hR（Oculus,Wetzlar,Germany）,Galilei（Ziemer,Switzerland）,Visante optical coherence tomography（Visante OCT,Carl Zeiss Meditec Inc.,Dublin,California,USA）,lOLMaster（Carl Zeiss Meditec,Jena,Germany）,and Lenstar LS 900/Biograph（haag-Streit AG,Koeniz,Switzerland/Alcon Laboratories Inc.,Ft Worth,Texas,USA）.

关键词： anterior camber depth measurement white to white measurement device interchangeability anterior chamber eye

Short-Term Response of Soil microbial Biomass to Different Chabazite Zeolite Amendments

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Pedosphere 2018年第2期28卷 277-287页

作者： Giacomo FERRETTI Katharina Maria KEIBLINGER Dario DI GIUSEPPE Barbara FACCINI Nicolò COLOMBANI Sophie ZEChMEISTER-BOLTENSTERN Massimo COLTORTI micòl MASTROCICCO Deptartment of Physics and Earth Sciences University of Ferrara Via Saragat 1 Ferrara 44122 (Italy) Institute of Soil Research Department of Forest and Soil Sciences University of Natural Resources and Life Sciences Vienna (BOKU) Peter Jordan Strasse 82 Vienna 1190 (Austria) Consorzio Nazionale Interuniversitario per le Scienze del Mare (CoNISMa) Piazzale Flaminio Roma 900196 (Italy) Department of Environmental Biological and Pharmaceutical Sciences and Technologies Second University of Naples Caserta 81100(Italy)

Zeolitites (ZTs) are rocks containing more than 50% of zeolite minerals and are known to be a suitable material for agricultural purposes by improving soil physicochemical properties and nitrogen (N) use efficiency. however, little is known about their effects on soil microbial biomass. This study aimed to evaluate short-term effects of different chabazite-rich ZT (ChAZT) amendments on soil microbial biomass and activity. A silty-clay agricultural soil was amended in three different ways, including the addition of natural (5% and 15%) and Nh_4^+-enriched (10%) ChAZT. Soil dissolved organic carbon (C), total dissolved N, Nh_4^+, NO_3^-, NO_2^-, microbial biomass C and N, and ergosterol were measured periodically over 16 d in a laboratory incubation. To verify the microbial immobilization of the N derived from Nh_4^+-enriched ChAZT, a high15N source was used for enriching the mineral to measure the microbial biomass δ15N signature. An increase in the ergosterol content was observed in the soil amended with 5% natural ChAZT. however, no similar result was observed in the soil amended with 15% natural ChAZT, suggesting that the fungal biomass was favored at a lower ChAZT application rate. In the soil amended with Nh+ 4-enriched ChAZT, microbial biomass N was related to NO_3^-production over time and inversely related to Nh_4^+, suggesting high nitrification process. Isotopic measurements on microbial biomass confirmed immediate assimilation of N derived from Nh_4^+-enriched ChAZT. These results suggested that the Nh_4^+-enriched ChAZT used in this study supplied an immediately available N pool to the microbial biomass.

关键词： ergosterol microbial biomass δ15N natural zeolite Nh4+-enriched zeolite nitrification slow-release fertilizer

Magnetic imaging-assisted colonoscopy vs conventional colonoscopy: A randomized controlled trial

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World Journal of Gastroenterology 2014年第36期20卷 13178-13184页

作者： Christopher W Teshima Sergio Zepeda-Gómez Suliman h AlShankiti Gurpal S Sandha Division of Gastroenterology University of Alberta Edmonton Alberta T6G 2X8 Canada

AIM: To compare magnetic imaging-assisted colonoscopy (mic) with conventional colonoscopy (CC).

关键词： Colonoscopy Conscious sedation Magnetic endoscope imaging Pain measurement Randomized controlled trial

An antimicrobial peptide from endophytic Fusarium tricinctum of Rhododendron tomentosum harmaja

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Fungal Diversity 2013年第3期60卷 153-159页

作者： M.V.Tejesvi D.R.Segura K.M.Schnorr D.Sandvang S.Mattila P.B.Olsen S.Neve T.Kruse h.h.Kristensen A.M.Pirttilä Departments of Biology University of OuluP.O.Box 3000LinnanmaaFIN-90014 OuluFinland Novozymes A/S Krogshoejvej 362880 BagsvaerdDenmark Departments of Chemistry University of OuluP.O.Box 3000LinnanmaaFIN-90014 OuluFinland

Endophytic microbes have attracted considerable attention as a completely new source of pharmaceuticals in recent *** endophytic Fusarium tricinctum was isolated from Rhododendron tomentosum,a shrub that is found widely across the northern *** endophytic *** produced antimicrobial compounds that were active against Staphylococcus carnosus,Candida albicans and *** transcriptome of the *** was sequenced,and a total of 12,006 contigs were assembled,having an N50 value of 1390 *** of the transcriptomic PD library of *** yielded an antimicrobial peptide named *** expression of Trtesin transcripts was>1000 fold in the mRNA library originating from PDB-grown fungi exhibiting high antimicrobial activity compared to FG4-grown fungi with no antimicrobial *** was cloned,expressed,and purified in pET32(a),and it consisted of 52 amino acids with 6 cysteine *** molecular weight of Trtesin is 6138.92 *** additional N-terminal sequencing was done to confirm the intact peptide,as well as to check the correct amino acid *** mic of Trtesin was determined against several bacteria as 64μg/mL,and peptide showed a mild activity against *** in agar diffusion assay,as a zone of inhibition of 10 mm was formed at 100μg of peptide.

关键词： Fungal defensin Antimicrobial Endophyte Transcriptome