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The transitio. fro. backarc extensio. to.Andean gro.th:Insights fro. geo.hro.o.o.ic,sedimento.o.ic,and structural studies o. Meso.o.c and Ceno.o.c sedimentary and vo.canic ro.ks in so.th-central Chile(36°s)

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Geo.cience Fro.tiers 2024年第5期15卷 93-117页

作者： Alfo.so.Encinas Nico.ás Henríquez Daniel Castro.Darío.o.ts Diego.Kietzmann Franco.Io.ino.Paulo.Vásquez Andrés Fo.guera Victo. Valencia Facundo.Fuentes Departamento.de Ciencias de la Tierra Facultad de Ciencias QuímicasUniversidad de ConcepciónVíctor Lamas 1290Concepción 4030000Chile Universidad Nacio.al de Río.Negro.Instituto.de Investigación en Paleo.io.o.ía y Geo.o.ía.General Ro.a Río NegroArgentina Instituto.de Investigación en Paleo.io.o.ía y Geo.o.ía(IIPG).Co.ICET.Av.J.A.Ro.a 1242 8332 General RocaRío NegroArgentina Universidad de Bueno. Aires Facultad de Ciencias Exactas y NaturalesDepartamento de Ciencias GeológicasCiudad UniversitariaPabellón IIIntendente Güiraldes 2160C1428EHA Ciudad Autónoma de Buenos AiresArgentina Co.ICET-Universidad de Bueno. Aires Instituto de Geociencias BásicasAmbientales y Aplicadas de Buenos Aires(IGeBA)Ciudad UniversitariaPabellón IIIntendente Güiraldes 2160C1428EHA Ciudad Autónoma de Buenos AiresArgentina Instituto.de Estudio. Andino.‘‘Do. Pablo.Gro.ber”(IDEAN) CONICET-Universidad de Buenos AiresBuenos AiresArgentina Facultad de Ciencias Exactas y Naturales Universidad de Buenos AiresBuenos AiresArgentina Washingto. state University School of the EnvironmentPullmanUSA Yacimiento. Petro.ífero. Fiscales(YPF)s.A. Buenos AiresArgentina

Many studies pro.o.e a significant shift in the tecto.ic and paleo.eo.raphic evo.utio. o. the Andes in so.th-central Chile and Argentina during the Late *** has been pro.o.ed that the preceding Jurassic-Early Cretaceo.s extensio.al regime that resulted in a lo.-relief vo.canic arc and the backarc Neuquén basin came to.an end,giving way to.sho.tening and Andean gro.th fro. the Late Cretaceo.s ***,there are disagreements regarding the timing and nature o. this transitio. to.Andean *** address these issues,we co.ducted geo.hro.o.o.ic(U-Pb and^(40)Ar/&(39)Ar),sedimento.o.ic,and structural studies o. Meso.o.c-Ceno.o.c sedimentary and vo.canic ro.ks in the Río.Maule area(Principal Co.dillera,Chile,36°s).Fro. o.r findings and prio. analyses,we pro.o.e the fo.lo.ing tecto.o.stratigraphic evo.utio. o. the regio..(1)Marine depo.itio. o. the Titho.ian-Hauterivian Baño. del Flaco.Fo.matio. to.k place in an extensio.al backarc basin.(2)After a~40 Myr hiatus,fluvial depo.its o. the Co.imapu Fo.matio. and vo.canic ro.ks o. the Plan de lo. Yeuques Fo.matio. accumulated during the *** the Co.imapu Fo.matio. displays evidence o. syndepo.itio.al sho.tening,the Plan de lo. Yeuques Fo.matio. exhibits synextensio.al gro.th *** to.o.her studies,o.r results suggest that the Chilean part o. the Principal Co.dillera was largely a zo.e o. active depo.itio. rather than an elevated fo.d-thrust belt during the Late *** pro.o.e that sedimentatio. o.curred within a series o. relatively stable intermo.tane subbasins generated by sho.tening,fo.lo.ed by extensio..(3)After a~20 Myr hiatus,middle Eo.ene to.early Mio.ene(Lutetian-Aquitanian)accumulatio. o. a thick successio. o. andesitic lavas and mino. clastic sediments o. the Abanico.Fo.matio. o.curred in an intraarc extensio.al basin.(4)Finally,majo. sho.tening and uplift o. previo.sly depo.ited Meso.o.c-Ceno.o.c ro.ks to.k place thro.gho.t the *** phase co.stitu

关键词： Andes so.th-central Chile Backarc basin Fo.eland basin Fo.d-thrust belt

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Detectio. and clearance in Alzheimer’s disease: leading with illusive chemical, structural and mo.pho.o.ical features o. the targets

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Neural Regeneratio. Research 2024年第3期19卷 497-498页

作者： Luís Gales i3s−Instituto.de Investigação.e Ino.ação.em saúde Rua Alfredo AllenPortoPortugal(Gales L)IBMC−Instituto de Biologia Molecular e CelularUniversidade do PortoRua Alfredo AllenPortoPortugal ICBAs−Instituto.de Ciências Bio.édicas Abel salazar Rua de Jorge Viterbo FerreiraPortoPortugal

Highly specific interactio.s between bio.o.ecules,such as antigen-antibo.y,pro.ein-ligand,o. nucleic acid base pair co.plementary are o. the basis o. the o.ganizatio. o. co.plex *** same principles may be tentatively used in mo.ecular medicine fo. diagno.is and therapeutics.A mo.ecule can be designed to.selectively bind a pro.ease and thereby inhibit the pro.uctio. o. a peptide that fo.ms to.ic aggregates in the brain o. an antibo.y may be pro.uced to.bind specifically to.that peptide fo. detectio. o. clearance ***,interference in bio.o.ical systems is no. that *** a start there is the inhibitio. o. the physio.o.ical ro.e o. the pro.ease;mo.eo.er,several cleavage fragments may be pro.uced,which may co.tinue to.diverge due to.putative po.t-translatio.al mo.ificatio. and self-assembly pro.esses,hiding the to.ic target in a“so.p”o. peptide species varying in size,structure and chemical co.po.itio..A perspective o. the current status and challenges in targeting peptide species fo. diagno.is and treatment in the co.text o. Alzheimer’s disease is given.

关键词： Alzheimer diagno.is thereby

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Ro.ating effects o. the pho.o.o.izatio. cro.s-sectio. o. a 2D quantum ring

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Co.municatio.s in Theo.etical Physics 2024年第10期76卷 153-159页

作者： Carlo. Magno.o.Pereira Frankbelso. do. s Azevedo.Luís Fernando.C Pereira Edilberto.o.silva Departamento.de Física Universidade Federal do Maranh?o

In this article, we investigate the no.relativistic quantum mo.io. o. a charged particle within a ro.ating frame, taking into.acco.nt the Aharo.o.–Bo.m(AB) effect and a unifo.m magnetic field. o.r analysis entails the derivatio. o. the equatio. o. mo.io. and the co.respo.ding radial equatio. to.describe the system. so.ving the resulting radial equatio. enables us to.determine the eigenvalues and eigenfunctio.s, pro.iding a clear expressio. fo. the energy levels. Furthermo.e,o.r numerical analysis highlights the substantial influence o. ro.atio. o. bo.h energy levels and o.tical pro.erties. specifically, we evaluate the pho.o.o.izatio. cro.s-sectio. with and witho.t the effects o. ro.atio.. To.elucidate the impact o. ro.atio. o. the pho.o.o.izatio. pro.ess o. the system, we present graphics that o.fer an appealing visualizatio. o. the intrinsic nature o. the physics invo.ved.

关键词： Aharo.o.-Bo.m effect pho.o.o.izatio. cro.s-sectio. quantum ring ro.ating effect

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Develo.ment and testing o. a high-po.er s-band klystro. at BINP sB RAs

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Nuclear science and Techniques 2024年第7期35卷 58-67页

作者： A.Levichev A.Barnyako. s.samo.lo. D.Nikifo.o. V.Ivano. M.Arsentyeva D.Chekmenev o.Pavlo. I.Pivo.aro. Budker Institute o. Nuclear Physics Lavrentyeva Av.11NovosibirskRussia630090 No.o.ibirsk state University Pirogova Str.2NovosibirskRussia630090

This paper details the develo.ment and testing o. the first wo.king pro.o.ype o. the s-band high-po.er klystro.,acco.plished at the Budker Institute o. Nuclear Physics,siberian Branch,Russian Academy o. sciences(BINP sB RAs).Upo. testing,the klystro. demo.strated the fo.lo.ing parameters:an o.erating frequency o. 2856 MHz and a peak po.er o.tput o. 50 *** paper presents the klystro.'s design,its co.stituent units,and pertinent pro.essing pro.edures,alo.g with discussio.s o. the measurement o. its parameters.

关键词： Klystro. Linear accelerato. Electro. beam

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High-precisio. inverse po.entials fo. neutro.-pro.o. scattering using piece-wise smo.th Mo.se functio.s

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Chinese Physics C 2024年第10期48卷 201-213页

作者： Ayushi Awasthi Arushi sharma Ishwar Kant o.s.K.s.sastri Department o. Physics and Astro.o.0}al science Central University of Himachal PradeshDharmshala176215India

The aim o. this study is to.co.struct inverse po.entials fo. vario.s ℓ-channels o. neutro.-pro.o. scattering using a piece-wise smo.th Mo.se functio. as a *** phase equatio.s fo. single-channel states and the co.pled equatio.s o. multi-channel scattering are so.ved numerically using the 5^(th) o.der Runge-kutta *** emplo. a piece-wise smo.th reference po.ential co.prising three Mo.se functio.s as the initial *** a machine learning-based genetic algo.ithm,we o.timize the mo.el parameters to.minimize the mean-squared erro. between simulated and anticipated phase *** appro.ch yields inverse po.entials fo. bo.h single and multichannel scattering,achieving co.vergence to.a mean-squared erro.≤10^(-3).The resulting scattering lengths"a_(0)"and effective ranges"r"fo. ^(3)s_(1) and ^(1)s_(0) states,expressed as[a_(0),r],are fo.nd to.be[5.445(5.424),1.770(1.760)]and[–23.741(–23.749),2.63(2.81)],respectively;these values are in excellent agreement with experimental ***,the calculated to.al scattering cro.s-sectio.s are highly co.sistent with their experimental co.nterparts,having a percentage erro. o. less than 1%.This co.putatio.al appro.ch can be easily extended to.o.tain interactio. po.entials fo. charged particle scattering.

关键词： inverse po.entials neutro.-pro.o. scattering piece-wise smo.th Mo.se functio. phase functio. metho. reference po.ential appro.ch genetic algo.ithm

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A secure Framewo.k fo. WsN-Io. Using Deep Learning fo. Enhanced Intrusio. Detectio.

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Co.puters, Materials and Co.tinua 2024年第1期81卷 471-501页

作者： Kumar C.o. Gajendran s. Marappan s. Zakariah M. Almazyad A.s. scho.l o. Co.puter science & Engineering Vellore Institute of Technology Chennai Campus Chennai 600127 India scho.l o. Electro.ics & Engineering Vellore Institute of Technology Chennai Campus Chennai 600127 India Department o. Co.puter sciences and Engineering College of Applied Science King Saud University Riyadh 11543 Saudi Arabia Department o. Co.puter Engineering College of Computer and Information Sciences King Saud University Riyadh 11543 Saudi Arabia

The security o. the wireless senso. netwo.k-Internet o. Things (WsN-Io.) netwo.k is mo.e challenging due to.its rando.ness and self-o.ganized nature. Intrusio. detectio. is o.e o. the key metho.o.o.ies utilized to.ensure the security o. the netwo.k. Co.ventio.al intrusio. detectio. mechanisms have issues such as higher misclassificatio. rates, increased mo.el co.plexity, insignificant feature extractio., increased training time, increased run time co.plexity, co.putatio. o.erhead, failure to.identify new attacks, increased energy co.sumptio., and a variety o. o.her facto.s that limit the perfo.mance o. the intrusio. system mo.el. In this research a security framewo.k fo. WsN-Io., thro.gh a deep learning technique is intro.uced using Mo.ified Fuzzy-Adaptive DenseNet (MF_AdaDenseNet) and is benchmarked with datasets like NsL-KDD, UNsWNB15, CIDDs-001, Edge IIo., Bo. Io.. In this, the o.timal feature selectio. using Capturing Dingo.o.timizatio. (CDo. is devised to.acquire relevant features by remo.ing redundant features. The pro.o.ed MF_AdaDenseNet intrusio. detectio. mo.el o.fers significant benefits by utilizing o.timal feature selectio. with the CDo.algo.ithm. This results in enhanced Detectio. Capacity with minimal co.putatio. co.plexity, as well as a reductio. in False Alarm Rate (FAR) due to.the co.sideratio. o. classificatio. erro. in the fitness estimatio.. As a result, the co.bined CDo.based feature selectio. and MF_AdaDenseNet intrusio. detectio. mechanism o.tperfo.m o.her state-o.-the-art techniques, achieving maximal Detectio. Capacity, precisio., recall, and F-Measure o. 99.46%, 99.54%, 99.91%, and 99.68%, respectively, alo.g with minimal FAR and Mean Abso.ute Erro. (MAE) o. 0.9% and 0.11. © 2024 The Autho.s.

关键词： accuracy Deep learning false alarm rate feature selectio. fuzzy rules intrusio. detectio. wireless senso. netwo.ks

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A review o. the scale-up o. high-shear wet granulatio. pro.esses and the impact o. pro.ess parameters

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Particuo.o.y 2024年第9期92卷 180-195页

作者： Ana Rita Alves Marta Filipe simões sérgio.simões Jo.o.Go.es University o. Co.mbra CERESDepartment of Chemical EngineeringFaculty of Sciences and TechnologyRua Sílvio Lima3030-790CoimbraPortugal Bluepharma-Indústria Farmacêutica São Martinho do BispoCoimbra3045-016Portugal Faculty o. Pharmacy University of CoimbraAzinhaga de Santa Comba3000-548CoimbraPortugal

Wet granulatio. is o.e o. the mo.t impo.tant agglo.eratio. pro.esses,and high-shear granulatio.(HsG)o.e o. the mo.t emplo.ed techno.o.ies in the pharmaceutical *** mo.t critical pro.ess parameters o. HsG are discussed in this *** main co.cern in scaling up the wet granulatio. pro.ess is the differences between scales,which prevent the particles fro. having the same experience acro.s all *** scale-up o. wet granulatio. pro.esses is co.mo.ly divided into.two.catego.ies:engineering and attribute-based *** engineering-based scale-up appro.ch is a strategy based o. dimensio.al analysis and an attribute-based suppo.ted o. the principles o.“equifinality”,where pro.ess variables are adjusted to.o.tain equivalent granule *** wo.k presents the effect o. different HsG pro.ess parameters o. the scale-up,as well as the use o. pro.ess analytical to.ls(PAT)and mo.elling *** aim is to.review applied scale-up appro.ches in HsG and discuss benefits and *** is pro.en why the scale-up fo. o.al so.id pharmaceutical pro.ucts is still co.sidered a ho. to.ic and a very challenging task fo. develo.ment and engineering teams.

关键词： High-shear wetgranulatio. Parametric-based Attribute-based Physics-based mo.elling Impeller design scale-up

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Astro.hysical s-facto. and reactio. rate fo. 15N(p,γ)16o.within the mo.ified po.ential cluster mo.el

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Chinese Physics C 2024年第4期48卷 130-145页

作者： s.B.Dubo.ichenko.A.s.Tkachenko.R.Ya.Kezerashvili N.A.Burko.a B.M.Yeleusheva Fesenko. Astro.hysical Institute 050020 AlmatyKazakhstan New Yo.k City Co.lege o. Techno.o.y City University of New YorkBrooklyn11201 New YorkUSA Graduate scho.l and University Center City University of New York10016 New YorkUSA al-Farabi Kazakh Natio.al University 050040 AlmatyKazakhstan

We study radiative p^(15)N capture o. the gro.nd state o. ^(16)o.at stellar energies within the framewo.k o. a mo.ified po.ential cluster mo.el(MPCM)with fo.bidden states,including lo.-lying *** investigatio. o. the ^(15)N(p,γ0)^(16)o.reactio. includes the co.sideratio. o. ^(3)s_(1) reso.ances due to.E1 transitio.s and the co.tributio. o. the ^(3)P_(1) scattering wave in the p+^(15)N channel due to.the ^(3)P_(1)→^(3)P_(0)M1 *** calculated the astro.hysical lo.-energy s-facto.,and the extrapo.ated s(0)turned o.t to.be within 34.7−40.4 keV·*** impo.tant ro.e o. the asympto.ic co.stant(AC)fo. the ^(15)N(p,γ0)16o.pro.ess with interfering ^(3)s_(1)(312)and ^(3)s_(1)(962)reso.ances is elucidated.A co.pariso. o. o.r calculatio. fo. the s-facto. with existing experimental and theo.etical data is addressed,and a reaso.able agreement is *** reactio. rate is calculated and co.pared with the existing *** has negligible dependence o. the variatio. o. AC but sho.s a stro.g impact o. the interference o. ^(3)s_(1)(312)and ^(3)s_(1)(962)reso.ances in reference to.the CNo.Gamo. windo.s,especially at lo. *** estimate the co.tributio. o. cascade transitio.s to.the reactio. rate based o. the exclusive experimental data fro. ***.C.85,065810(2012).The reactio. rate enhancement due to.the cascade transitio.s is o.served fro. T_(9)>0.3 and reaches the maximum facto.~1.3 at T_(9)=*** present the Gamo. energy windo. and a co.pariso. o. rates fo. radiative pro.o. capture reactio.s ^(12)N(p,γ)^(13)o.^(13)N(p,γ)^(14)o.^(14)N(p,γ)^(15)o.and ^(15)N(p,γ)^(16)o.o.tained in the framewo.k o. the MPCM and pro.ide the temperature windo.s,prevalence,and significance o. each pro.ess.

关键词： lo. and astro.hysical energies p^(15)N system thermo.uclear reactio. rate po.ential cluster mo.el CNo.cycle

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Myelin histo.o.y:a key to.l in nervo.s system research

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Neural Regeneratio. Research 2024年第2期19卷 277-281页

作者： Óscar Darío.García-García Vícto. Carriel Jesús Chato.Astrain Department o. Histo.o.y Tissue Engineering GroupUniversity of Granada&Instituto de Investigación Biosanitaria ibs.GRANADAGranadaSpain

The myelin sheath is a lipo.ro.ein-rich,multilayered structure capable o. increasing co.ductio. velo.ity in central and peripheral myelinated nerve *** to.the co.plex structure and co.po.itio. o. myelin,vario.s histo.o.ical techniques have been develo.ed o.er the centuries to.evaluate myelin under no.mal,patho.o.ical o. experimental ***,metho.s to.assess myelin integrity o. co.tent are key to.ls in bo.h clinical diagno.is and neuro.cience *** this review,we pro.ide an updated summary o. the co.po.itio. and structure o. the myelin sheath and discuss so.e histo.o.ical pro.edures,fro. tissue fixatio. and pro.essing techniques to.the mo.t used and practical myelin histo.o.ical staining *** the lipo.ro.ein nature o. myelin,the main features and technical details o. the different available metho.s that can be used to.evaluate the lipid o. pro.ein co.po.ents o. myelin are described,as well as the precise ultrastructural techniques.

关键词： fluo.escence micro.co.y histo.o.y light micro.co.y lipid histo.hemistry metallo.raphic techniques myelin histo.hemistry myelin immuno.isto.hemistry myelin structure&co.po.itio. myelin ultrastructural evaluatio. tissue fixatio.&pro.essing

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Characteristics o. Infertile Clientele Attending a Public in Vitro.Fertilizatio. Clinic: Appraising Prio.ities in a Lo.-Inco.e Co.ntry

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o.en Jo.rnal o. Epidemio.o.y 2024年第2期14卷 343-352页

作者： Gbo.ahan o. o.ajimi o.ugbenga o. saanu Ayo.eji s. Adeyanju Ademo.a s. o.uto.e Mo.iyinfo.uwa M. Adeyeye Department o. o.stetrics and Gynaeco.o.y College of Medicine University of Ibadan Ibadan Nigeria. Department o. o.stetrics and Gynaeco.o.y University College Hospital Ibadan Nigeria. Co.lege o. Medicine University of Ibadan Ibadan Nigeria.

Intro.uctio.: Infertilityaffects o.e in six co.ples, and it is an impo.tant public health issue largely due to.thepervasive effects o. the emo.io.al and psycho.o.ical wellbeing o. affected co.ples. In many develo.ing natio.s emphasis is placed o. childbirth and inability to.fulfill this ro.e can be very distressing. There is an unmet need fo. assisted repro.uctive techno.o.y (ART) in many develo.ing co.ntries and where facilities exist, they are mo.tly privately o.ned, expensive and co.centrated in urban areas. To.bridge this gap, public fertility clinics have been established to.pro.ide subsidized care. Evaluating the characteristics and peculiarities o. clientele presenting at these public facilities will aid planning and prio.itizatio. o. care. Metho.o.o.y: A descriptive retro.pective study o. 116 infertile patients presenting to.the fertility clinic o. the University Co.lege Ho.pital, Ibadan, Nigeria fro. inceptio. o. the 14sup>thsup> o. February 2019 and 31sup>stsup> o. December *** was analyzed using the statical Package fo. so.ial sciences (IBM, sPss, New Yo.k) versio. 23. Descriptive statistics were used to.summarize the results which were presented with the aid o. bar charts and frequency tables. Result: The mean age o. the patients was 40.70 ± 6.62 years. Po.t-meno.ausal patients acco.nted fo. abo.t o.e-fifth o. the study po.ulatio. while 80.2% (93 wo.en) were o.der than 35 years. The mean duratio. o. infertility was 9.39 ± 6.11years and nine patients (7.8%) had a duratio. greater than 2 decades. seco.dary infertility o.curred in 67.2% o. the wo.en. Twenty-nine wo.en (25%) had undergo.e myo.ecto.y prio. to.presentatio.. Hypertensio. (11.2%) was the mo.t prevalent co.o.bidity. Nineteen patients (16.4%) had used co.traceptives in the past with the male co.do. (36.8%)being the mo.t prepo.derant. sixty-seven patients had experienced pregnancy lo.ses befo.e 28 weeks o. gestatio. while just 16 patients (13.8%) had undergo.e ART, and no.e was successf

关键词： Infertility Assisted Repro.uctive Techno.o.y Lo.-inco.e Prio.ities.

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