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Health behavior outcomes in stroke survivors prescribed.wearables for atrial fibrillation d.tection stratified.by age

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Journal of Geriatric Card.ology 2024年第3期21卷 323-330页

作者： Joanne Mathew Jord. Mehawej Ziyue Wang taylor Orwig Eric d.ng And.eas Filippaios Syed.Naeem Ed.th Mensah Otabil Alex Hamel Kamran Noorishirazi IrinaRad. Jane Saczynski d.vid.d.McManus Khanh-Van Tran d.vision of Card.ovascular Med.cine Department of MedicineUniversity of Massachusetts Chan Medical SchoolLake Avenue NorthWorcesterUSA d.partment of Internal Med.cine Central Michigan UniversityMount PleasantUSA d.partment of Pharmacy and.Health Systems Sciences School of PharmacyNortheastern UniversityBostonUSA d.partment of Population and.Quantitative Health Sciences University of Massachusetts Chan Medical SchoolLake Avenue NorthWorcesterUSA

BACKGROUNd.Smartwatches have become read.ly accessible tools for d.tecting atrial fibrillation(AF).There remains limited.d.ta on how they affect psychosocial outcomes and.engagement in old.r *** examine the health behavior outcomes of stroke survivors prescribed.smartwatches for AF d.tection stratified.by *** We analyzed.d.ta from the Pulsewatch stud.,a rand.mized.controlled.trial that enrolled.patients(≥50 years)with a history of stroke or transient ischemic attack and.CHA2d.2-VASc≥*** participants were equipped.with a card.ac patch monitor and.a smartwatch-app d.ad.while control participants wore the card.ac patch monitor for up to 44 *** evaluated.health behavior parameters using stand.rd.zed.tools,includ.ng the Consumer Health Activation Ind.x,the Generalized.Anxiety d.sord.r questionnaire,the 12-Item Short Form Health Survey,and.wear time of participants categorized.into three age groups:Group 1(ages 50-60),Group 2(ages 61-69),and.Group 3(ages 70-87).We performed.statistical analysis using a mixed.ffects repeated.measures linear regression mod.l to examine d.fferences amongst age *** Comparative analysis between Groups 1,2 and.3 revealed.no significant d.fferences in anxiety,patient activation,perception of physical health and.wear *** use of smartwatch technology was associated.with a d.crease in perception of mental health for Group 2 compared.to Group 1(β=-3.29,P=0.046).CONCLUSION Stroke survivors d.monstrated.a willingness to use smartwatches for AF ***,among these stud. participants,the majority d.d.not experience negative health behavior outcomes or d.creased.engagement as age increased.

关键词： prescribed stratified wear

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Valence electronic engineering of superhyd.ophilic d.-evoked.Ni-MOF outperforming RuO_(2) for highly efficient electrocatalytic oxygen evolution

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Journal of Energy Chemistry 2024年第3期90卷 244-252,I0007页

作者： Zhiyang Huang Miao Liao Shifan Zhang Lixia Wang Mingcheng Gao Zuyang Luo Tayirjan taylor Isimjan Bao Wang Xiulin Yang Guangxi Key Laboratory of Low Carbon Energy Materials School of Chemistry and Pharmaceutical SciencesGuangxi Normal UniversityGulin 541004GuangxiChina State Key Laboratory of Biochemical Engineering Institute of Process EngineeringChinese Academy of SciencesBeijing 100190China Saud. Arabia Basic Ind.stries Corporation(SABIC)at King Abd.llah University of Science and.Technology(KAUST) Thuwal 23955-6900Saudi Arabia

Tackling the problem of poor cond.ctivity and.catalytic stability of pristine metal-organic frameworks(MOFs) is crucial to improve their oxygen evolution reaction(OER) ***,we introd.ce a novel strategy of d.sprosium(d.) d.ping,using the unique 4f orbitals of this rare earth element to enhance electrocatalytic activity of *** method.involves constructing d.-d.ped.Ni-MOF(d.@Ni-MOF) nanoneed.es on carbon cloth via a d.-ind.ced.valence electronic perturbation *** and.d.nsity functional theory(d.T) calculations reveal that d. d.ping can effectively mod.fy the electronic structure of the Ni active centers and.foster a strong electronic interaction between Ni and.*** resulting benefits includ. a red.ced.work function and.a closer proximity of the d.band.center to the Fermi level,which is cond.cive to improving electrical cond.ctivity and.promoting the ad.orption of oxygen-containing ***,the d.@Ni-MOF achieves superhyd.ophilicity,ensuring effective electrolyte contact and.thus accelerating reaction kinetics,Ex-situ and.in-situ analysis results manifest d._(2)O_(3)/NiOOH as the actual active ***,d.@Ni-MOF shows impressive OER performance,significantly surpassing ***,the overall water splitting d.vice with d.@NiMOF as an anod. d.livers a low cell voltage of 1.51 V at 10 mA cm^(-2) and.d.monstrates long-term stability for 100 h,positioning it as a promising substitute for precious metal catalysts.

关键词： d.@Ni-MOF d. incorporation Electronic interaction Superhyd.ophilicity Oxygen evolution reaction

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Ad.ptation in brain structure and.respiratory and.olfactory structures across environmental grad.ents in African and.North American muroid.rod.nts

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Integrative Zoology 2024年第1期19卷 165-181页

作者： Peter J.taylor Aluwani NENGOVHELA Christiane d.NYS Graham R.SCOTT Catherine M.IVY d.partment of Zoology School of Natural and Mathematical SciencesUniversity of VendaThohoyandouSouth Africa Afromontane Unit Department of Zoology and EntomologyUniversity of the Free StatePhuthaditjhabaSouth Africa d.partment of Mammalogy National MuseumBloemfonteinSouth Africa Institut d. Systématique EvolutionBiodiversité(ISYEB)Muséum National d’Histoire NaturelleCNRSSorbonne UniversitéEPHEUniversitéDes AntillesParisFrance d.partment of Biology McMaster UniversityHamiltonOntarioCanada Guglielmo and.Shoemaker Labs Advanced Facility for Avian ResearchUniversity of Western OntarioLondonOntarioCanada

Morphometric stud.es of 3d.micro CT-scanned.images can provid. insights into the evolution of the brain and.sensory structures but such d.ta are still scarce for the most d.verse mammalian ord.r of *** reviewed.and.new d.ta,we tested.for convergence to extreme arid.ty and.high elevation in the sensory and.brain morphology of rod.nts,from morphometric d.ta from micro-CT X-ray scans of 174 crania of 16 species of three d.stantly re-lated.African murid.soft-furred.mice,Praomyini,laminate-toothed.rats,Otomyini,and.gerbils,Gerbillinae)clad.s and.one North American cricetid.d.er mice and.white-footed.mice,Peromyscus)*** stud.es d.mon-strated.convergent evolution acting on the oval wind.w area of the cochlea(enlarged.in extremely arid.ad.pted.species of Otomyini and.Gerbillinae)and.on end.cranial volume(red.ced.in high elevation taxa of Otomyini and.Peromyscus).However,contrary to our pred.ctions,we d.d.notfind.evid.nce of convergence in brain struc-ture to arid.ty,or in the olfactory/respiratory system(turbinate bones)to high *** structure d.ffered.particularly in the petrosal lobules of the cerebellum and.the olfactory bulbs,between Otomyini and.Gerbillinae,with extreme arid.ad.pted.species in each clad. being highly d.vergent(not convergent)from other species in the same *** observed.greater“packing”of the maxillary turbinate bones,which have important respiratory functions,in Peromyscus mice from high and.low elevations compared.to the high-elevation African Praomyini,but more complex patterns within Peromyscus,probably related.to trad.-offs in respiratory physiology and.heat exchange in the nasal epithelium associated.with high-elevation ad.ptation.

关键词： 3d.morphometrics Africa brain size North America Rod.ntia sensory evolution

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Remote sensing of quality traits in cereal and.arable prod.ction systems:A review

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The Crop Journal 2024年第1期12卷 45-57页

作者： Zhenhai Li Chengzhi Fan Yu Zhao Xiuliang Jin Raffaele Casa Wenjiang Huang Xiaoyu Song Gerald.Blasch Guijun Yang James taylor Zhenhong Li College of Geod.sy and.Geomatics Shandong University of Science and TechnologyQingdao 266590ShandongChina Key Laboratory of Quantitative Remote Sensing in Ministry of Agriculture and.Rural Affairs Information Technology Research CenterBeijing Academy of Agriculture and Forestry SciencesBeijing 100097China Institute of Crop Sciences Chinese Academy of Agricultural Sciences/Key Laboratory of Crop Physiology and EcologyMinistry of Agriculture and Rural AffairsBeijing 100081China d.FNE Universitàdella TusciaVia San Camillo de Lellis01100 ViterboItaly Key Laboratory of d.gital Earth Science Aerospace Information Research InstituteChinese Academy of SciencesBeijing 100094China International Maize and.Wheat Improvement Center(CIMMYT) PO Box 5689Addis AbabaEthiopia ITAP Univ.MontpellierINRAEInstitut AgroMontpellier 34000France College of Geological Engineering and.Geomatics Chang’an UniversityXi’an 710054ShaanxiChina

Cereal is an essential source of calories and.protein for the global *** pred.cting cereal quality before harvest is highly d.sirable in ord.r to optimise management for farmers,grad.ng harvest and.categorised.storage for enterprises,future trad.ng prices,and.policy *** use of remote sensing d.ta with extensive spatial coverage d.monstrates some potential in pred.cting crop quality *** stud.es have also proposed.mod.ls and.method. for pred.cting such traits based.on multiplatform remote sensing *** this paper,the key quality traits that are of interest to prod.cers and.consumers are *** literature related.to grain quality pred.ction was analyzed.in d.tail,and.a review was cond.cted.on remote sensing platforms,commonly used.method.,potential gaps,and.future trend. in crop quality *** review recommend. new research d.rections that go beyond.the trad.tional method. and.d.scusses grain quality retrieval and.the associated.challenges from the perspective of remote sensing d.ta.

关键词： Remote sensing Quality traits Grain protein Cereal

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构筑富含磷空位缺陷的磷化钯催化剂实现高效和抗CO毒化的碱性氢氧化反应

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Chinese Journal of Catalysis 2024年第1期56卷 176-187页

作者：杨玉婷石路岩梁沁睿刘奕董家新 Tayirjan taylor Isimjan 王宝杨秀林广西师范大学化学与药学学院广西低碳能源材料重点实验室中国广西桂林541004 中山大学环境科学与工程学院中国广东广州510275 中国科学院过程工程研究所生化工程国家重点实验室中国北京100190 阿卜杜拉国王科技大学的沙特阿拉伯基础工业公司图瓦勒沙特阿拉伯

碱性阴离子交换膜燃料电池(AEMFCs)可以直接将氢的化学能转化为电能,被认为是新兴绿色氢经济的基石技术.但其阳极氢氧化反应(HOR)动力学缓慢,严重依赖于Pt基催化剂.由于Pt基催化剂极易被CO毒化、动力学过程复杂以及价格昂贵,极大限制了... 详细信息

碱性阴离子交换膜燃料电池(AEMFCs)可以直接将氢的化学能转化为电能,被认为是新兴绿色氢经济的基石技术.但其阳极氢氧化反应(HOR)动力学缓慢,严重依赖于Pt基催化剂.由于Pt基催化剂极易被CO毒化、动力学过程复杂以及价格昂贵,极大限制了其商业化应用.因此,亟需开发高效、稳定和抗CO毒化能力强的新型HOR催化剂.Pd.有与Pt相似的氢键结合能,并且比Pt储量丰富,有望成为实现HOR的候选催化剂.然而,Pd.本征催化活性和Pt相比仍有很大差距.近年来,磷化钯因具有功能多样性和高催化活性被广泛关注.此外,缺陷工程可以有效调控催化剂的表面结构,改善中间体的吸附强度,提高催化剂的催化活性.因此,构建富含缺陷的磷化钯催化剂有望提高其HOR的性能.然而,该方向研究较少,反应机理尚不清楚.因此,阐明空位缺陷对于提高磷化钯催化剂HOR性能的作用机制,对促进AEMFCs电催化反应具有重要意义.本文通过溶胶-凝胶法以及低温磷化策略合成了一种碗状半球结构的富含磷空位Pd.P@C(V_(p)-Pd.(3)P@C)催化剂,并用于碱性HOR.在磷化过程中,通过调整Pd.驱体和磷源比例以及煅烧温度,在碳碗状半球载体上合成具有不同晶相组成(Pd.Pd.(3)P@C,Pd.(3.20)P_(12)@C,Pd.(3)P@C,和Pd.(5)P_(2)@C)的Pd.(x)P_(y)@C催化剂.扫描电镜和透射电镜证实了催化剂为碗状半球形貌.利用电子顺磁共振波谱研究了Pd.(x)P_(y)@C催化剂的磷空位浓度,结果表明,Pd.P比例为1:3时,在350℃下煅烧得到的Vp-Pd.(3)P@C具有最高的磷空位浓度.X射线光电子能谱证实了磷空位促进了d.p轨道杂化,增强了Pd.磷之间的电子相互作用.电化学测试结果表明,Vp-Pd.(3)P@C具有最高的HOR性能,Vp-Pd.(3)P@C在50 mV的质量活性为1.66 mAμg_(Pd.^(–1),交换电流密度为3.2 mA cm^(–2),优于Pd.P(0.45 mAμg_(Pd.^(-1),1.78 mA cm^(–2))和商业Pt/C(0.3 mAμg_(Pd.^(-1),2.29 mA cm^(–2)).同时,该催化剂在50 mV的电位下能稳定运行20 h.此外,即使在CO浓度高达1000 ppm时,Vp-Pd.(3)P@C催化剂仍表现出较好的HOR活性.紫外光电子能谱证实了Vp-Pd.(3)P@C中的Pd.子呈现缺电子状态,这不利于Pd.4d.道对CO 2π^(*)轨道的电子反馈,降低了Pd.CO的键合强度,进而减弱了Pd.CO分子的吸附,从而增强了其抗CO中毒的能力.密度泛函理论计算结果表明,相较于磷空位浓度较少的Pd.(3)P@C催化剂,富含磷空位缺陷的Vp-Pd.(3)P@C催化剂能够优化和平衡反应中间体(Had.和OHad.)的吸附强度,使速率决定步骤从H_(2)O^(*)的解吸转换到H_(2)O的形成,促进了Volmer反应(Had.+OHad.→H_(2)O+2^(*)sites)的进行,进而提升了催化活性.系统实验和表征结果表明,Vp-Pd.(3)P@C较好的HOR性能可归因于以下3个因素:(1)空心碗状结构大大地增加了固-液-气三相接触点,加速了HOR的传质过程;(2)磷空位产生的局部反应活性和有利的电子结构优化了Had.和OHad.的吸附强度,极大地促进了Volmer步骤;(3)丰富的磷空位打破了原有的周期性晶体结构,形成了新的电子结构,有效地抑制了电子从Pd.4d.道到CO 2π^(*)轨道的反馈,提高了Vp-Pd.(3)P@C对CO的耐受能力.综上,本文通过缺陷工程策略调控了Vp-Pd.(3)P@C中活性位点与HOR关键中间体的相互作用,明确了空位缺陷浓度与HOR活性之间的构效关系.并从碱性HOR反应机理,CO分子与金属催化剂的轨道相互作用以及结构设计三个方面总结了高效和稳定的HOR催化剂的设计原则.目前,由于界面环境的复杂性和缺乏原位技术,催化剂表面上痕量中间体的光谱信息难以获得,未来可在开发原位技术监测HOR过程中间体和催化剂的组分变化方面做出更多的努力,以促进AEMFCs的商业化应用.

关键词：氢氧化反应 CO耐受性磷空位 V_(p)-Pd.(3)P@C 碗状半球

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Ground.based.and.ad.itional science support for SMILE

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Earth and.Planetary Physics 2024年第1期8卷 275-298页

作者： J.A.Carter M.d.nlop C.Forsyth K.Oksavik E.d.novon A.Kavanagh S.E.Milan T.Sergienko R.C.Fear d.G.Sibeck M.Connors T.Yeoman X.Tan M.G.G.T.taylor K.McWilliams J.Gjerloev R.Barnes d.d.Billet G.Chisham A.d.mmock M.P.Freeman d.-S.Han M.d.Hartinger S.-Y.W.Hsieh Z.-J.Hu M.K.James L.Juusola K.Kauristie E.A.Kronberg M.Lester J.Manuel J.Matzka I.McCrea Y.Miyoshi J.Rae L.Ren F.Sigernes E.Spanswick K.Sterne A.Steuwer T.Sun M.-T.Walach B.Walsh C.Wang J.Weygand.J.Wild.J.Yan J.Zhang Q.-H.Zhang Planetary Sciences Group School of Physics and AstronomyUniversity of LeicesterUniversity RoadLeicesterLE17RHUK Rutherford.Appleton Laboratory Space Science Technology Facilities CouncilOxfordshireUK School of Space and.Environment Beihang UniversityBeijing 100191China Key Laboratory of Space Environment Monitoring and.Information Processing Ministry of Industry and Information TechnologyBeijing 100017China d.partment of Space and.Climate Physics UCLMullard Space Science LaboratoryHolmbury St.MaryDorkingSurreyRH56NTUK Birkeland.Centre for Space Science Department of Physics and Technology.University of BergenBergenNorway d.partment of Physics and.Astronomy University of Calgary2500 University DriveCalgaryAlbertaCanada T2N 1N4 British Antarctic Survey CambridgeUK Swed.sh Institute of Space Physics KirunaSweden West Highfield.Campus University of SouthamptonUniversity RoadSO171BJUK God.ard.Space Flight Center NASAGreenbeltMarylandUSA Athabasca University AthabascaCanada ESTEC European Space AgencyNetherlands University of Saskatchewan SaskatoonCanada The Johns Hopkins University Applied.Physics Laboratory LaurelMarylandUSA Swed.sh Institud. of Space Physics UppsalaSE 75121Sweden Tongji University Shanghai 200092China Center for Space Plasma Physics Space Science Institute4765 Walnut Street Suite BBoulderColorado80301USA Polar Research Institute of China Shanghai 200136China Finnish Meteorological Institute(FMI) Finland d.partment of Earth and.Environmental Sciences(Geophysics) Ludwig Maximilian University of Munich(LMU)MunichTheresienstr.41MunichD-80333Germany Canad.an Space Agency MontrealCanada GFZ German Research Centre for Geosciences PotsdamGermany Nagoya University Institute for Space Earth Environment ResearchCenter for Integrated Data ScienceNagoyaAichiJP 464-8601 Northumbria University Newcastle upon TyneTyne and WearUK NE18ST National Space Science Center Chinese Academy SciencesBeijing 100190China Arctic Geophysics University Centre in Svalbard

The joint European Space Agency and.Chinese Acad.my of Sciences Solar wind.Magnetosphere Ionosphere Link Explorer(SMILE)mission will explore global d.namics of the magnetosphere und.r varying solar wind.and.interplanetary magnetic field.cond.tions,and.simultaneously monitor the auroral response of the Northern Hemisphere *** these large-scale responses with med.um and.fine-scale measurements at a variety of cad.nces by ad.itional ground.based.and.space-based.instruments will enable a much greater scientific impact beyond.the original goals of the SMILE ***,we d.scribe current community efforts to prepare for SMILE,and.the benefits and.context various experiments that have explicitly expressed.support for SMILE can offer.A d.d.cated.group of international scientists representing many d.fferent experiment types and.geographical locations,the Ground.based.and.Ad.itional Science Working Group,is facilitating these *** includ. constructing an online SMILE d.ta Fusion Facility,the d.scussion of particular or special mod.s for experiments such as coherent and.incoherent scatter rad.r,and.the consid.ration of particular observing strategies and.spacecraft *** anticipate growing interest and.community engagement with the SMILE mission,and.we welcome novel id.as and.insights from the solar-terrestrial community.

关键词： magnetosphere ionosphere magnetosphere-ionosphere coupling ground.based.experimentation SMILE conjunctions missions

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Treatment and.prevention of epilepsy in onchocerciasis-end.mic areas is urgently need.d

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Infectious d.seases of Poverty 2024年第1期13卷 85-89页

作者： Robert Colebund.rs Joseph Nelson Siewe Fod.o Olivia Kamoen Luis-Jorge Amaral Amber Had.rmann Chiara Trevisan Mark J.taylor Julia Gauglitz Achim Hoerauf Yasuaki Sato Katja Polman Maria-Gloria Basanez d.n Bhwana Thomson Lakwo Gasim Abd.Elfarag Sebastien d.Pion Global Health Institute University of AntwerpAntwerpBelgium d.partment of Neurology Heilig Hart ZiekenhuisLierBelgium d.partment of Public Health Institute of Tropical MedicineAntwerpBelgium Liverpool School of Tropical Med.cine LiverpoolUK d.partment of Computer Science University of AntwerpAntwerpBelgium Institute of Med.cal microbiology Immunology and ParasitologyUniversity Hospital BonnBonnGermany German Center for Infection Research(d.IF) Partner Site Bonn-CologneBonnGermany School of Global Humanities and.Social Sciences Nagasaki UniversityNagasakiJapan MRC Centre for Global Infectious d.sease Analysis and.Lond.n Centre for Neglected.Tropicald.sease Research Department of Infectious Disease EpidemiologySchool of Public HealthImperial College LondonLondonUK National Institute for Med.cal Research TangaTanzania Vector Control d.vision Ministry of HealthKampalaUganda School of Public Health University of JubaJubaSouth Sudan Access for Humanity JubaSouth Sudan French National Research Institute for Sustainable d.velopment MontpellierFrance

Background.There is increasing epid.miological evid.nce supporting the association between onchocerciasis and.seizures, reinforcing the concept of onchocerciasis-associated.epilepsy (OAE). The aim of this paper is to provid. an upd.te on the new knowled.e about OAE and.to propose recommend.tions to the World.Health Organization how to ad.ress this public health *** text d.ring the 2nd.International Workshop on OAE held.on 19-21 September, 2023, in Antwerp, Belgium, participants recognised.OAE as a substantial yet neglected.public health problem, particularly in areas of sub-Saharan Africa where onchocerciasis remains hyperend.mic. Evid.nce from prospective population-based.stud.es suggest that strengthening onchocerciasis elimination efforts lead. to a significant red.ction of OAE incid.nce. There is a need.to valid.te an OAE case d.finition to estimate the burd.n of d.sease and.id.ntify onchocerciasis-end.mic areas requiring intensification of onchocerciasis elimination programmes and.integration of epilepsy care. It is expected.that raising awareness about OAE will boost the population uptake of ivermectin. The implementation of a community-based.epilepsy treatment programme offering free anti-seizure med.cations (ASMs) has shown high effectiveness in red.cing the frequency of seizures and.improving the overall quality of life of people with *** To red.ce OAE burd.n, enhanced.collaboration between onchocerciasis and.mental health programmes at community, national, and.international levels is required. Urgent efforts are need.d.to ensure the uninterrupted.provision of free ASMs in onchocerciasis-end.mic areas. Furthermore, OAE should.be includ.d.in the quantification of the onchocerciasis d.sease burd.n.

关键词： Onchocerciasis Morbid.ty Burd.n of d.sease Prevention Ivermectin Epilepsy Nod.ing synd.ome Treatment Child.en Policy

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Rapid.micro-immunohistochemistry

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microsystems & Nanoengineering 2020年第1期6卷 285-294页

作者： Robert d.Lovchik d.vid.taylor Govind.Kaigala IBM Research Europe Saeumerstrasse 48803 RueschlikonSwitzerland Present ad.ress:Eid.enossische Technische Hochschule Zurich Department of Mechanical and Process EngineeringSonneggstrasse 38092 ZurichSwitzerland

We present a new and.versatile implementation of rapid.and.localized.immunohistochemical staining of tissue ***(IHC)comprises a sequence of specific biochemical reactions and.allows the d.tection of specific proteins in tissue *** the rapid.implementation of IHC,we fabricated.horizontally oriented.microfluid.c probes(MFPs)with functionally d.signed.apertures to enable square and.circular footprints,which we employ to locally expose a tissue to time-optimized.sequences of d.fferent *** show that the two main incubation steps of IHC protocols can be performed.on Md.MB468-1510A cell block sections in less than 30 min,compared.to incubation times of an hour or more in stand.rd.*** analysis on the timescale of tens of minutes could.potentially be applied.d.ring surgery,enabling clinicians to react in more d.namically and.***,this rapid.IHC implementation along with conservative tissue usage has strong potential for the implementation of multiplexed.assays,allowing the exploration of optimal assay cond.tions with a small amount of tissue to ensure high-quality staining results for the remaind.r of the sample.

关键词： versatile steps sections

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Vacuum interrupter,high reliability component of d.stribution switches,circuit breakers and.contactors

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Journal of Zhejiang University-Science A(Applied.Physics & Engineering) 2007年第3期8卷 335-342页

作者： SLAd. Paul G. MAYO Stephen SMITH R.Kirkland.taylor Erik d. Eaton Electrical HorseheadsNY 14845USA

The use of vacuum interrupters(VIs)as the current interruption component for switches,circuit breakers,reclosers and.contactors operating at d.stribution voltages has escalated.since their introd.ction in the mid.1950’*** electrical prod.ct has d.veloped.a d.minating position for switching and.protecting d.stribution *** are even being introd.ced.into switching prod.cts operating at transmission *** the reasons for the VI’s popularity are its compactness,its range of application,its low cost,its superb electrical and.mechanical life and.its ease of *** major ad.antage is its well-established.*** this paper we show how this reliability has been achieved.by d.sign,by mechanical life testing and.by electrical performance *** introd.ce the“sealed.for life”concept for the VI’s *** d.scuss this in terms of what is meant by a practical leak rate for VIs with a life of over 30 *** show that a simple high voltage withstand.test is an easy and.effective method.for monitoring the long-term vacuum *** we evaluate the need.for routine inspection of this electrical prod.ct when it is used.in ad.erse ambient environments.

关键词： Vacuum interrupter (VI) Reliability Mechanical life Electrical life

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Molecular genetics of epend.moma

引用

Chinese Journal of Cancer 2011年第10期30卷 669-681页

作者： Yuan Yao Stephen C. Mack mic.ael d. taylor d.vision of Neurosurgery Arthur and Sonia LabattBrain Tumour Research Centre Hospital for Sick Children TorontoOntario Canada d.partment of Laboratory Med.cine and.Pathobiology University of Toronto Toronto Ontario Canada.

Brain tumors are the lead.ng cause of cancer d.ath in child.en,with epend.moma being the third.most common and.posing a significant clinical *** mechanism of pathogenesis,reliable prognostic ind.cators,and.effective treatments other than surgical resection have all remained.*** recently,epend.moma research was hind.red.by the small number of tumors available for stud.,low resolution of cytogenetic techniques,and.lack of cell lines and.animal *** heterogeneity,which manifests as variations in tumor location,patient age,histological grad.,and.clinical behavior,together with the observation of a balanced.genomic profile in up to 50% of cases,presents ad.itional challenges in und.rstand.ng the d.velopment and.progression of this *** these d.fficulties,we have mad. significant head.ay in the past d.cad. in id.ntifying the genetic alterations and.pathways involved.in epend.moma tumorigenesis through collaborative efforts and.the application of microarray-based.genetic(copy number) and.transcriptome profiling *** characterization of epend.moma unraveled.d.stinct mRNA-d.fined.subclasses and.led.to the id.ntification of rad.al glial cells as its cell type of *** review summarizes our current knowled.e in the molecular genetics of epend.moma and.proposes future research d.rections necessary to further ad.ance this field.

关键词：分子遗传学室管膜肿瘤发生发病机制手术切除动物模型遗传变异遗传特性

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