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Relationship between bacteria and phytoplankton during the giant jellyfish Nemopilema nomurai bloom in an oligotrophic temperate marine ecosystem

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Acta Oceanologica Sinica 2016年第10期35卷 107-113页

作者： zeng Yang HUANg Xuguang HUANg Bangqin mi Tiezhu Key Laboratory of Coastal and Wetland Ecosystems of ministry of Education Xiamen University Fujian Provincial Key Laboratory of Coastal Ecology and Environmental Studies Xiamen University College of Chemistry and Chemical Engineering Ocean University of China

Bacterial abundance, phytoplankton community structure and environmental parameters were investigated to study the relationships between bacteria and phytoplankton during giant jellyfish Nemopilema nomurai blooms in the central Yellow Sea during 2013. N. nomurai appeared in June, increased in August, reached a peak and began to degrade in September 2013. Results showed that phosphate was possible a key nutrient for both phytoplankton and bacteria in June, but it changed to nitrate in August and September. Phytoplankton composition significantly changed that pico-phytoplankton relative biomass significantly increased, whereas other size phytoplankton significantly decreased during jellyfish bloom. In June, a significantly positive correlation was observed between chlorophyll a concentration and bacterial abundance（r=0.67, P0.001, n=34）.During jellyfish outbreak in August, there was no significant correlation between phytoplankton and bacteria（r=0.11, P0.05, n=25）, but the relationship（r=0.71, P0.001, n=31） was rebuilt with jellyfish degradation in September. In August, small size phytoplankton occupied the mixed layer in offshore stations, while bacteria almost distributed evenly in vertical. Chlorophyll a concentration significantly increased from（0.42±0.056） μg/L in June to（0.74±0.174） μg/L in August, while bacterial abundance just slightly increased. Additionally, the negative net community production indicated that community respiration was not entirely determined by the local primary productivity in August. These results indicated that jellyfish blooms potentially affect coupling of phytoplankton and bacteria in marine ecosystems.

关键词： jellyfish bloom Nemopilema nomurai phytoplankton pigments jellyfish DOM ecological consequence

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DNA Nanotechnology Mediated gold Nanoparticle Conjugates and Their Applications in Biomedicine

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Chinese Journal of Chemistry 2016年第3期34卷 299-307页

作者： ChenguangWang Huan Zhang Dongdong zeng Lili San Xianqiang mi Laboratory of System Biology Shanghai Advanced Research Institute Chinese Academy of Sciences Shanghai 201210 China University of Chinese Academy of Sciences Beijing 100049 China

gold nanoparticles （Au NPs） provide numerous biomedical applications with unique chemical and physical properties. Au NPs can be readily synthesized, and modified with multiple chemical or biological molecules, mak- ing them excellent candidates for biosensor, in vitro and in vivo imaging, drug delivery and catalysis. Perfect spe- cific DNA base-pairing can not only serve as genetic information carriers but also construct novel nanostructures and hybrid conjugates with inorganic nanomaterials such as Au NPs. On one hand, based on the unique DNA char- acters including unparalleled base pairing, double helix with precise diameter and programmable sequences, various DNA statical nanostructures with well-defined size, shape and dynamic structures as well as controlled functions have been created through using DNA nanotechnology. On the other hand, rapid developments in nanotechnology and nanoscience have new questions on how DNA and DNA structures interact with inorganic nanomaterials, which should be important for their biological and biomedical applications. In this review, we intend to provide an over- view on recent advanced Au NPs-based DNA conjugates for biomedical applications, mainly including the func- tionalization of Au NPs （Au NPs-based DNA conjugates interact with Au-S bond or Au-polyA）; application of Au NPs-based conjugates in biomedicine, such as biosensing, drug delivery and therapy, and Au NPs-DNA conjugates based advanced nanostructures.

关键词： gold nanoparticles nanomaterials biomedical application surface chemistry

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Signaling pathways in the regulation of cytokine release syndrome in human diseases and intervention therapy

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Signal Transduction and Targeted Therapy 2021年第11期6卷 3230-3245页

作者： Xia Li mi Shao Xiangjun zeng Pengxu Qian He Huang Bone Marrow Transplantation Center The First Affiliated HospitalZhejiang University School of MedicineHangzhouPeople’s Republic of China Liangzhu Laboratory Zhejiang University Medical Center1369 West Wenyi RoadHangzhou311121People’s Republic of China Institute of Hematology Zhejiang UniversityHangzhouZhejiangPeople’s Republic of China Zhejiang Province Engineering Laboratory for Stem Cell and Immunity Therapy HangzhouZhejiangPeople’s Republic of China Center of Stem Cell and Regenerative Medicine Zhejiang University School of MedicineHangzhouPeople’s Republic of China

Cytokine release syndrome(CRS)embodies a mixture of clinical manifestations,including elevated circulating cytokine levels,acute systemic inflammatory symptoms and secondary organ dysfunction,which was first described in the context of acute graft-versus-host disease after allogeneic hematopoietic stem-cell transplantation and was later observed in pandemics of influenza,SARS-CoV and COVID-19,immunotherapy of tumor,after chimeric antigen receptor T(CAR-T)therapy,and in monogenic disorders and autoimmune ***,severe CRS is a very significant and life-threatening complication,which is clinically characterized by persistent high fever,hyperinflammation,and severe organ ***,CRS is a double-edged sword,which may be both helpful in controlling tumors/viruses/infections and harmful to the *** a high incidence and high levels of cytokines are features of CRS,the detailed kinetics and specific mechanisms of CRS in human diseases and intervention therapy remain *** the present review,we have summarized the most recent advances related to the clinical features and management of CRS as well as cutting-edge technologies to elucidate the mechanisms of *** that CRS is the major adverse event in human diseases and intervention therapy,our review delineates the characteristics,kinetics,signaling pathways,and potential mechanisms of CRS,which shows its clinical relevance for achieving both favorable efficacy and low toxicity.

关键词： cytokine release kinetics

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Nucleon ~3pF_2 Superfluid Pairing gap in Asymmetry Nuclear Matter

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Communications in Theoretical Physics 2009年第6期51卷 1113-1116页

作者： mi Ai-Jun ZUO Wei LI zeng-Hua Umberto Lombardo Institute of Modern Physics Chinese Academy of Sciences 730000 Lanzhou China School of Nuclear Science and Technology Lanzhou University 730000 Lanzhou China INFN-LNS and Universit di Catania Catania 1-95123 Italy

The 3 P F2 superfluidity of neutron and proton is investigated in isospin-asymmetric nuclear matter within the Brueckner-Hartree-Fock approach and the BCS theory by adopting the Argonne V14 and the Argonne V18 nucleonnucleon interactions. We find that pairing gaps in the 3PF2 channel predicted by adopting the AV14 interaction are much larger than those by the AV18 interaction. As the isospin-asymmetry increases, the neutron 3 pF2 superfluidity is found to increase rapidly, whereas the proton one turns out to decrease and may even vanish at high enough asymmetries. As a consequence, the neutron 3pF2 superfluidity is much stronger than the proton one at high asymmetries and it predominates over the proton one in dense neutron-rich matter.

关键词： 3pF2 superfluidity asymmetric nuclear matter Brueckner-Hartree-Fock approach BCS theory

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Characterization of a broad-energy germanium detector for its use in CJPL

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Nuclear Science and Techniques 2017年第1期28卷 42-48页

作者： Zhi zeng Yu-Hao mi mi.g zeng Hao Ma Qian Yue Jian-Ping Cheng Jun-Li Li Rui Qiu Hui Zhang Key Laboratory of Particle and Radiation Imaging (ministry of Education) and Department of Engineering Physics Tsinghua University Beijing 100084 China

The broad-energy germanium(BEge)detector,with the ability of background discrimination using pulse shape discrimination,is a competitive candidate for neutrinoless double beta decay(ovββ)*** this paper,we report our measurements of key parameters for detector modeling in a commercial p-type BEge ***-like sources are used to investigate energy resolution and linearity of the detector.A cylindrical volume source is used for efficiency *** an assembled device for source positioning and a collimated ^(133)Ba source,the detector is scanned to check its active *** an^(241)Am point-like source,the dead layer thicknesses is measured at about 0.17 mm on the front and 1.18 mm on the *** detector characterization is of importance for BEge detectors to be used in the ovββ experiments at China JinPing underground Laboratory(CJPL).

关键词： BEge Characterization Dead layer 0mbb CJPL

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microstructure and Tensile Properties of Spray-deposited IC6 Alloy

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Journal of Materials Science & Technology 1998年第2期14卷 143-146页

作者： mi, guofa Li, Zhou Tian, Shifan Zhao, Xianguo Luo, Zhiping zeng, Songyan Li, Qingchun Inst Aeronaut Mat Beijing 100095 Peoples R China Harbin Inst Technol Sch Mat Sci & Engn Harbin 150001 Peoples R China

The microstructure and mechanical properties of a Ni//3 Al based Ni-Al-Mo superalloy-IC6 which possesses low impurity content and high density by spray deposition technique have been studied. The results indicate that the IC6 alloy has good tensile strength and elongation both at room and intermediate temperatures. (Edited author abstract) 6 Refs.

关键词： Nickel alloys

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Asymmetric intramolecular oxa-michael addition of activated α,β-unsaturated ketones by chiral N-triflyl phosphoramide

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Chinese Science Bulletin 2010年第17期55卷 1723-1725页

作者： FENg Zhen zeng mi XU QingLong YOU ShuLi State Key Laboratory of Organometallic Chemistry Shanghai Institute of Organic Chemistry Chinese Academy of Sciences Shanghai 200032 China

Asymmetric intramolecular oxa-michael addition of activated α,β-unsaturated ketones by chiral N-triflyl phosphoramide was realized. The flavanone products can be synthesized with excellent yields (50%–95%) and up t... 详细信息

关键词：迈克尔分子氧不对称不饱和黄酮活性手性膦

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Establishment and validation of an adherence prediction system for lifestyle interventions in non-alcoholic fatty liver disease

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World Journal of gastroenterology 2024年第10期30卷 1393-1404页

作者： mi.g-Hui zeng Qi-Yu Shi Liang Xu Yu-Qiang mi Clinical School of the Second People’s Hospital Tianjin Medical UniversityTianjin 300192China Department of gastroenterology Cangzhou People’s HospitalCangzhou 061000Hebei ProvinceChina Department of Hepatology Tianjin Second People’s HospitalTianjin 300192China Tianjin Research Institute of Liver Diseases Tianjin 300192China

BACKgROUND Non-alcoholic fatty liver disease(NAFLD)is the most common liver disease worldwide,affecting about 1/4th of the global population and causing a huge global economic *** date,no drugs have been approved for the treatment of NAFLD,making the correction of unhealthy lifestyles the principle method of *** patients with poor adherence to lifestyle correction and attempting to improve their adherence are therefore very *** To develop and validate a scale that can rapidly assess the adherence of patients with NAFLD to lifestyle *** The Exercise and Diet Adherence Scale(EDAS)was designed based on com-pilation using the Delphi method,and its reliability was subsequently *** and laboratory indicators were measured,and patients completed the EDAS questionnaire at baseline and after 6 *** efficacy of the EDAS was evaluated in the initial ***,the efficacy of the EDAS was internally verified in a validation *** The EDAS consisted of 33 items in six dimensions,with a total of 165 *** EDAS score correlated significantly with daily number of exercise and daily reduction in calorie intake(Pght loss.A total score of 116 was excellent in predicting adherence to daily reduction in calorie intake(>500 kacl/d),(sensitivity/specificity was 100.0%/75.8%),while patients score below 97 could nearly rule out the possibility of daily exercise(sensitivity/specificity was 89.5%/44.4%).Total EDAS scores≥116,97-115,andgood,average,and poor adherence,respectively,to diet and exercise *** The EDAS can reliably assess the adherence of patients with NAFLD to lifestyle interventions and have clinical application in this population.

关键词： Fatty liver Lifestyle intervention Behavioral change Patient adherence Compliance

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Electrochemical formation and phase control of Mg-Li alloys

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Chinese Chemical Letters 2007年第9期18卷 1124-1128页

作者： Zhang, mi Lin Chen, zeng Han, Wei Lv, Yan Zhuo Wang, Jun Harbin Engn Univ Key Lab Superlight Mat & Surface Technol Minist Educ Harbin 150001 Peoples R China

The electrochemical formation of Mg-Li alloys was investigated in a molten LiCl-KCl (58-42 mol%) eutectic melt at 723 K. The cyclic voltammogram. for a Mo electrode showed that the electroreduction of Li+ proceeds in a single step and the deposition potential of Li metal was -2.40 V (vs. Ag/AgCl). For Mg electrode, the electroreduction of Li+ takes place at less cathodic potential than that at the Mo electrode which was caused by the formation of Mg-Li alloys. Phase of the deposited Mg-Li alloys could be controlled by the electrolysis potential, and the samples were characterized by X-ray diffraction and scanning electron microscopy. The results showed that alpha-Mg and beta-Li phases were obtained at -2.35 and -2.55 V, respectively. (c) 2007 mi Lin Zhang. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

关键词： LiCl-KCl molten salt electrodeposition Mg-Li alloy

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microstructure and properties of ZL205 Alloy

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China Foundry 2008年第1期5卷 24-27页

作者： mi.guofa Wang Kuangfei gong Haijun Wang Hongwei zeng Songyan School of Materials Science and Engineering Henan Polytechnic University Jiaozuo 454000 China School of Materials Science and Engineering Harbin Institute of Technology Harbin 150001 China

The microstructure, precipitate type, precipitate distribution and tensile strength of a ZL205 alloy, beforeand after ageing treatment, have been studied by means of optical microscopy and transmission electron *** results showed that the as-cast microstructure of the alloy was made up of α-Al and eutectic phase distributedat the grain boundaries. During ageing treatment, the tensile strength increased at first and then reduced with time,and the highest ultimate tensile strength was found to be around 488.2 MPa.

关键词： Al-Cu alloy grain refinement mechanical property microstructure

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