检索结果-南通市图书馆

Baseline Characteristics and Treatment Patterns of the Patients Recruited to the china Registry of Hepatitis B

在线全文

学校读者我要写书评

暂无评论

Journal of Clinical and Translational Hepatology 2019年第4期7卷 322-328页

作者： Shan Shan Hong You Junqi Niu Jia Shang Wen Xie Yuexin Zhang Xun Li Hong Ren Hong Tang Huiguo Ding Xihong Wang Yuemin Nan Xiaoguang Dou Tao Han Lingyi Zhang Xiaoqing Liu Cunliang Deng Jilin Cheng Xiaozhong Wang Qing Xie Shumei Lin Yan Huang Youqing Xu Yong Xiong Wu Li Xuebing Yan Hongxin Piao Wenxiang Huang Qinghua Lu Weijin Gong Shiping Li Xiaoxuan Hu Xiaolan Zhang Shourong Liu Yufang Li Dongliang Yang Hai Li Caixia Yang Mingliang Cheng Liaoyun Zhang Huanwei Zheng Xinhua Luo Feng Lin Lei Wang Guanghua Xu Xiaoyuan Xu Lai Wei Jinlin Hou Zhongping Duan Hui Zhuang Xizhong Yang Yuanyuan Kong Jidong Jia the CR-HepB study group,Beijing,china Liver Research Center Beijing Friendship HospitalCapital Medical UniversityBeijing Key Laboratory of Translational Medicine on Liver CirrhosisNational Clinical Research Center for Digestive DiseasesBeijingChina Department of Hepatology First Hospital of Jilin UniversityChangchunJilinChina Department of Infectious Diseases Henan Provincial People's HospitalZhengzhouHenanChina Center of Liver Diseases Beijing Ditan HospitalCapital Medical UniversityBeijingChina Department of Infectious Diseases First Affiliated Hospital of Xinjiang Medical UniversityUrumqiXinjiangChina Department of General Surgery The First Hospital of Lanzhou UniversityLanzhouGansuChina Department of Infectious Diseases The Second Affiliated Hospital of Chongqing Medical UniversityChongqingChina Center of Infectious Diseases West China Hospital of Sichuan UniversityChengduSichuanChina Department of Gastroenterology and Hepatology Beijing Youan HospitalCapital Medical UniversityBeijingChina Center of Infectious Diseases The Third People's Hospital of TaiyuanTaiyuanShanxiChina Department of Traditional and Western Medical Hepatology The Third Hospital of Hebei Medical UniversityShijiazhuangHebeiChina Department of Infectious Diseases Shengjing Hospital of China Medical UniversityShenyangLiaoningChina Department of Hepatology Tianjin Third Central HospitalTianjin Medical UniversityTianjinChina Department of Hepatology Lanzhou University Second HospitalLanzhouGansuChina Department of Infectious Diseases Peking Union Medical College HospitalBeijingChina Department of Infectious Diseases The Affiliated Hospital of Southwest Medical UniversityLuzhouGansuChina Department of Gastroenterology Shanghai Public Health Clinical CenterShanghaiChina Department of Hepatology Xinjiang Uygur Autonomous Region Traditional Chinese Medicine HospitalUrumqiXinjiangChina Department of Infectious Diseases Shanghai Ruijin HospitalJiao Tong University School of MedicineShanghaiChina Department of Infectious Diseases Th

Background and Aims: Chronic hepatitis B virus(HBV)in-fection remains a major public health problem ***,we describe the baseline characteristics and treatment pro-files of HBV-infected patients recruited to the china Registry of Hepatitis ***: Inclusion criteria were patients with different stages of chronic HBV infection and complete key *** criteria were patients with hepatocellular *** baseline clinical,laboratory and treatment pro-files were ***: Finally,40,431 patients were *** median age was 43 years,with 65.2%being men and 51.3%being positive for hepatitis B e antigen(HBeAg).The most common initial diagnosis was chronic hep-atitis B(81.0%),followed by cirrhosis(9.3%),inactive carrier of hepatitis B surface antigen(HBsAg)(6.7%),and immune tolerant phase of hepatitis B infection(3.0%).Among the 21,228 patients who were on treatment,88.0%,10.0%and 2.0%received nucleos(t)ide analogues(NAs),interferon or combination of NAs and interferon,*** propor-tion of patients who received preferred NAs(entecavir or te-nofovir disoproxil fumarate)had increased from 13.5%in 2003 to 79.7%in ***: We concluded that middle-aged men accounted for most of the patients with chronic hepatitis B in this cross-sectional *** half of the patients were *** were the most com-monly used therapy,and use of the preferred NAs had steadily increased in the past decade.

关键词： Hepatitis B Treatment Registry

河南偃师二里头文化时期陶片的穆斯堡尔谱研究

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

核技术 1984年第4期 67-67页

作者：孙仲田金国樵潘贤家郑州大学

“二里头文化”是我国古代灿烂文化的一个组成部分。二里头遗址作为探索夏代文化的重要内容已被考古工作者所重视。本文给出了二里头不同时期的五个灰陶样品的室温ME谱及计算机处理结果。由五个灰陶片的穆斯堡尔谱图可看出均没有磁性... 详细信息

“二里头文化”是我国古代灿烂文化的一个组成部分。二里头遗址作为探索夏代文化的重要内容已被考古工作者所重视。本文给出了二里头不同时期的五个灰陶样品的室温ME谱及计算机处理结果。由五个灰陶片的穆斯堡尔谱图可看出均没有磁性分裂峰出现,这说明二里头陶器原料中没有添加晶化良好的赤铁矿（Fe2O3）成份,主要是由颗粒很细的粘土矿烧制而成。在非磁性中央峰右侧都出现一个强烈的Fe2+离子

关键词：二里头文化非磁性中央峰烧结温度穆斯堡尔谱

Clinical practice guideline for transurethral plasmakinetic resection of prostate for benign prostatic hyperplasia(2021 Edition)

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Military Medical Research 2022年第5期9卷 515-533页

作者： Xian-Tao Zeng Ying-Hui Jin Tong-Zu Liu Fang-Ming Chen De-Gang Ding Meng Fu Xin-Quan Gu Bang-Min Han Xing Huang Zhi Hou Wan-Li Hu Xin-Li Kang Gong-Hui Li Jian-Xing Li Pei-Jun Li Chao-Zhao Liang Xiu-Heng Liu Zhi-Yu Liu Chun-Xiao Liu Jiu-Min Liu Guang-Heng Luo Yi Luo Wei-Jun Qin Jian-Hong Qiu Jian-Xin Qiu Xue-Jun Shang Ben-Kang Shi Fa Sun Guo-Xiang Tian Ye Tian Feng Wang Feng Wang Yin-Huai Wang Yu-Jie Wang Zhi-Ping Wang Zhong Wang Qiang Wei Min-Hui Xiao Wan-Hai Xu Fa-Xian Yi Chao-Yang Zhu Qian-Yuan Zhuang Li-Qun Zhou Xiao-Feng Zou Nian-Zeng Xing Da-Lin He Xing-Huan Wang 无 Department of Urology Institute of UrologyZhongnan Hospital of Wuhan UniversityWuhan430071China Center for Evidence-Based and Translational Medicine Zhongnan Hospital of Wuhan UniversityWuhan430071China Department of Urology Tianjin Third Central Hospital Affiliated To Nankai UniversityTianjin300170China Department of Urology Henan Provincial People’s HospitalZhengzhou University People’s HospitalZhengzhou450003China Department of Urology Beijing Tsinghua Changgung HospitalSchool of Clinical MedicineTsinghua UniversityBeijing102218China Department of Urology China-Japan Union Hospital of Jilin UniversityChangchun130033China Department of Urology Shanghai General HospitalShanghai Jiao Tong University School of MedicineShanghai200080China Department of Urology Qinghai University Affiliated HospitalXi’ning810012China Department of Urology People’s Hospital of Hainan ProvinceHainan Affiliated Hospital of Hainan Medical University HaikouHaikou570311China Department of Urology Sir Run Run Shaw HospitalZhejiang University School of MedicineHangzhou310016China Department of Urology General Hospital of Ningxia Medical UniversityYinchuan750003China Department of Urology The First Affiliated Hospital of Anhui Medical UniversityHefei230022China Department of Urology Renmin Hospital of Wuhan UniversityWuhan430060China Department of Urology The Second Hospital of Dalian Medical UniversityDalian116023LiaoningChina Department of Urology Zhujiang Hospital of Southern Medical UniversityGuangzhou510282China Department of Urology Guangdong Provincial People’s HospitalGuangdong Academy of Medical SciencesGuangzhou510080China Department of Urology Surgery Guizhou Province People’s HospitalGuiyang550002China Department of Urology Xijing Hospital of Air Force Military Medical UniversityXi’an710032China Department of Urology The 980St Hospital of the PLA Joint Logistics Support Force(Bethune International Peace Hospital of PLA)Shijiazhuang050082China Department of Urology

Benign prostatic hyperplasia (BPH) is highly prevalent among older men, impacting on their quality of life, sexual function, and genitourinary health, and has become an important global burden of disease. Transurethral plasmakinetic resection of prostate (TUPKP) is one of the foremost surgical procedures for the treatment of BPH. It has become well established in clinical practice with good efficacy and safety. In 2018, we issued the guideline “2018 Standard Edition”. However much new direct evidence has now emerged and this may change some of previous recommendations. The time is ripe to develop new evidence-based guidelines, so we formed a working group of clinical experts and methodologists. The steering group members posed 31 questions relevant to the management of TUPKP for BPH covering the following areas: questions relevant to the perioperative period (preoperative, intraoperative, and postoperative) of TUPKP in the treatment of BPH, postoperative complications and the level of surgeons’ surgical skill. We searched the literature for direct evidence on the management of TUPKP for BPH, and assessed its certainty generated recommendations using the grade criteria by the European Association of Urology. Recommendations were either strong or weak, or in the form of an ungraded consensus-based statement. Finally, we issued 36 statements. Among them, 23 carried strong recommendations, and 13 carried weak recommendations for the stated procedure. They covered questions relevant to the aforementioned three areas. The preoperative period for TUPKP in the treatment of BPH included indications and contraindications for TUPKP, precautions for preoperative preparation in patients with renal impairment and urinary tract infection due to urinary retention, and preoperative prophylactic use of antibiotics. Questions relevant to the intraoperative period incorporated surgical operation techniques and prevention and management of bladder explosion. The application to different

关键词： Transurethral plasmakinetic resection of prostate Benign prostatic hyperplasia Recommendation Treatment Guideline

哮喘治疗依从性与肺功能和控制水平的相关性分析

在线全文

学校读者我要写书评

暂无评论

中国呼吸与危重监护杂志 2022年第11期21卷 761-767页

作者：王文雅林江涛刘春涛唐华平霍建民顾玉海刘荣玉陈萍袁雅冬杨晓红许建英孙德俊李娜嘉姜淑娟陈一强王长征杨岚刘晓菊杨冬张伟陈卓昌林其昌周建英周新胡成平蒋萍周玮张捷蔡绍曦邱晨黄茂黄奕江刘辉国中国哮喘研究协作组中日友好医院呼吸与危重症医学科国家呼吸疾病临床研究中心北京100029 四川大学华西医院呼吸与危重症医学科四川成都610041 青岛市立医院呼吸与危重症医学科山东青岛266071 哈尔滨医科大学第一附属医院呼吸科黑龙江哈尔滨150001 青海省人民医院呼吸科青海西宁810007 安徽医科大学第一附属医院呼吸与危重症医学科安徽合肥230022 北部战区总医院呼吸科辽宁沈阳110016 河北医科大学第二附属医院呼吸科河北石家庄050004 新疆维吾尔自治区人民医院呼吸与危重症医学科新疆乌鲁木齐830001 山西白求恩医院呼吸与危重症医学科山西太原030032 内蒙古人民医院呼吸与危重症医学科内蒙古呼和浩特010017 大庆油田总医院呼吸科黑龙江大庆163311 山东省人民医院呼吸与危重症医学科山东济南251411 广西医科大学第一附属医院呼吸内科广西南宁530021 陆军医科大学新桥医院呼吸内科重庆410037 西安交通大学附属第一医院呼吸与危重症医学科陕西西安710061 兰州大学第一医院老年呼吸科甘肃兰州730000 复旦大学附属中山医院呼吸内科上海200032 南昌大学第一附属医院呼吸内科江西南昌330006 河南省人民医院呼吸内科河南郑州450003 福建医科大学第一附属医院呼吸内科福建福州350005 浙江大学医学院附属第一医院呼吸内科浙江杭州310003 上海交通大学医学院附属上海市第一人民医院呼吸内科上海200080 中南大学湘雅医院呼吸与危重症医学科湖南长沙410008 天津市第一中心医院呼吸内科天津300192 宁夏医科大学总医院呼吸与危重症医学科宁夏银川750003 吉林大学第二医院呼吸与危重症医学科吉林长春130041 南方科技大学附属南方医院呼吸与危重症医学科广东广州510515 暨南大学第二临床医学院深圳市人民医院呼吸与危重症医学科广东深圳518020 南京医科大学附属第一医院呼吸与危重症医学科江苏南京211103 海南省人民医院呼吸与危重症医学科海南海口570031 华中科技大学同济医学院附属同济医院呼吸内科湖北武汉430030 不详

目的分析未控制的哮喘患者药物治疗依从性与肺功能、气道炎症水平、哮喘控制水平以及患者生活质量之间的关系,为改善患者依从性和提高哮喘控制水平提供依据。方法以我国内地28个省市32家三甲医院未达到哮喘控制且依从性差的哮喘患者... 详细信息

目的分析未控制的哮喘患者药物治疗依从性与肺功能、气道炎症水平、哮喘控制水平以及患者生活质量之间的关系,为改善患者依从性和提高哮喘控制水平提供依据。方法以我国内地28个省市32家三甲医院未达到哮喘控制且依从性差的哮喘患者作为研究对象,通过问卷调查的方式收集患者一般资料,所有患者均行肺功能、气道炎症水平检测,分析我国成人哮喘患者治疗依从性。结果调查共计923例患者,调查问卷回收率100%。哮喘疾病认知相关问题回答完全正确者占243例(26.33%),哮喘疾病认知相关问题不能完全回答正确者占680例(73.67%)。哮喘患者治疗依从性与肺功能指标呈正相关,与呼出气一氧化氮呈明显负相关。治疗依从性高的哮喘患者,其哮喘控制水平和生活质量更高。哮喘患者治疗依从性不佳将会导致肺功能下降和气道炎症水平升高,使哮喘控制水平以及生活质量下降。结论哮喘治疗依从性与肺功能及气道炎症水平、哮喘控制水平和生活质量相关。

关键词：支气管哮喘治疗依从性哮喘控制生活质量肺功能

癌症筛查项目人员组成及工作负荷的多中心调查及建议

在线全文

学校读者我要写书评

暂无评论

中华流行病学杂志 2018年第3期39卷 295-301页

作者：孙宗祥石菊芳兰莉毛阿燕黄慧瑶雷海科邱五七董佩朱娟王德斌刘国祥白亚娜孙晓杰廖先珍任建松郭兰伟周琦杨莉宋冰冰杜灵彬朱琳龚继勇刘玉琴任英买玲秦明芳张永贞周金意孙校华吴寿岭齐啸娄培安蔡波张凯赫捷代敏无哈尔滨市疾病预防控制中心 150056 国家癌症中心、中国医学科学院北京协和医学院肿瘤医院北京100021 中国医学科学院医学信息研究所北京100020 重庆市肿瘤研究所 400030 安徽医科大学卫生管理学院合肥230032 哈尔滨医科大学卫生管理学院 150081 兰州大学公共卫生学院流行病与卫生统计学研究所 730000 山东大学卫生管理与政策研究中心济南250012 广西医科大学南宁530021 河南省肿瘤医院郑州450008 哈尔滨医科大学附属肿瘤医院 150081 浙江省肿瘤医院杭州310022 新疆医科大学附属肿瘤医院乌鲁木齐830011 山东省肿瘤医院济南250117 甘肃省肿瘤医院兰州730050 铁岭市中心医院 112000 云南省肿瘤医院昆明650118 山西省肿瘤医院太原030013 江苏省疾病预防控制中心南京210009 宁波市第二医院 315010 开滦总医院唐山063000 唐山市人民医院 063001 市疾病预防控制中心徐州221006 南通市肿瘤医院 226000 城市癌症早诊早治项目卫生经济学评价工作组

目的从癌症筛查服务人员组成和工作服务负荷，了解癌症筛查项目的可持续性。方法2014-2015年基于城市癌症早诊早治项目，在16个省份项目点选取2013-2015年所有承担项目的医院（71．1％为三甲医院）、CDC和社区中心，采用纸质问卷和网络... 详细信息

目的从癌症筛查服务人员组成和工作服务负荷，了解癌症筛查项目的可持续性。方法2014-2015年基于城市癌症早诊早治项目，在16个省份项目点选取2013-2015年所有承担项目的医院（71．1％为三甲医院）、CDC和社区中心，采用纸质问卷和网络调查，访谈对象包括宏观管理人员、具体项目管理人员和一线工作人员等，内容包括不同专业人员配备情况、工作人员工作负荷及补偿情况等。结果完成合格调查4626份，年龄（37．7±9．5）岁，男性占31．0％。省份间投人人员数量差别较大，以2012年加入项目的8个可比省份为例，副高及以上人员数量为6人（重庆）至43人（北京）不等；细化不同专业间差别也较大。不同机构来源工作人员中，医院（n=2192）、CDC（n=431）和社区中心人员（n=1990）自报因参加项目工作量增加所致压力较大的占比依次为19．9％、24．6％和34．1％（P〈0．001）。对应不同项目角色分类人员，宏观管理（n=227）、项目具体管理人员（n=376）和一线工作人员（n=3908）自报压力较大的比例依次为23．6％、22．3％和28．2％（P〈0．001）。3244名（73．8％）工作人员为项目工作加班获得报酬或补偿，其中以与工作量挂钩的劳务费（67．5％）和工作量不挂钩劳务费（26．6％）形式最多见。结论省份间人员配置情况提示各现场的组织模式不同，客观能力可能存在差异。若要长期可持续性开展癌症筛查工作，建议筛查工作趋向常规化，减轻社区和一线工作人员压力，提高物质和非物质激励，可设专职人员。

关键词：肿瘤筛查供方可持续性能力工作负荷

重型创伤性脑损伤合并新型冠状病毒感染成人患者临床诊疗中国专家共识(2023版)

在线全文

学校读者我要写书评

暂无评论

中华创伤杂志 2023年第3期39卷 193-203页

作者：张泽立孙守家包义君别黎曹云星晁彦公陈菊祥方文华冯光冯雷冯军峰高亮韩冰莎韩萍胡成功胡锦胡荣何伟侯立军黄贤键江基尧江荣才李立宏李晓鹏刘劲芳刘杰吕胜青邱炳辉孙西周孙晓川田恒力田野王珂王宁王新军王东海王玉海汪建军王新功魏俊吉徐峰徐敏晏骖闫伟杨小锋杨朝华张睿张永明赵迪朱建新高国一黄齐兵中国医疗保健国际交流促进会重症医学分会山东大学齐鲁医院济南250012 中国医科大学附属第一医院沈阳110001 吉林大学白求恩第一医院长春130032 重庆医科大学第二附属医院重庆400010 清华大学附属第一医院北京100016 海军军医大学第一附属医院上海200433 福建医科大学第一附属医院福州350005 河南省人民医院郑州450003 济宁市第一人民医院济宁272500 上海交通大学医学院附属仁济医院上海200127 上海市第十人民医院上海200072 四川大学华西医院成都610041 复旦大学附属华山医院上海200040 陆军军医大学第一附属医院重庆400038 山东大学齐鲁医院青岛分院青岛266035 海军军医大学第二附属医院上海200003 深圳市第二人民医院深圳518035 天津医科大学总医院天津300052 空军军医大学唐都医院西安710038 新疆医科大学附属第一医院乌鲁木齐830011 中南大学湘雅医院长沙410008 烟台毓璜顶医院烟台264099 陆军军医大学第二附属医院重庆400037 南方医科大学南方医院广州510515 日照市中医医院日照276800 重庆医科大学附属第一医院重庆400016 上海交通大学附属第六人民医院上海200233 首都医科大学附属北京宣武医院北京100053 郑州大学第五附属医院郑州450052 联勤保障部队第九〇四医院无锡214041 山东第一医科大学第一附属医院济南250014 临沂市人民医院临沂276034 北京协和医院北京100032 胜利油田中心医院东营257034 浙江大学医学院附属第二医院杭州310009 浙江大学医学院附属第一医院杭州310003 青岛大学附属医院青岛266003 安徽医科大学附属第二医院合肥230601 河北省中医院石家庄050013 聊城市脑科医院聊城252001 首都医科大学附属北京天坛医院北京100070 不详

重型创伤性脑损伤(sTBI)合并新型冠状病毒感染(COVID-19)的患者病情复杂,主要表现为sTBI可显著增高COVID-19发展为重型或危重型的概率;COVID-19也可增加sTBI的手术风险和术后肺部病变的严重程度,并且在治疗过程中存在诸多矛盾点,为该类... 详细信息

重型创伤性脑损伤(sTBI)合并新型冠状病毒感染(COVID-19)的患者病情复杂,主要表现为sTBI可显著增高COVID-19发展为重型或危重型的概率;COVID-19也可增加sTBI的手术风险和术后肺部病变的严重程度,并且在治疗过程中存在诸多矛盾点,为该类患者的临床救治带来困难。截至目前,可供医务人员参考的有关sTBI合并COVID-19的临床研究和诊疗规范甚少。为规范该类患者的临床治疗,中国医疗保健国际交流促进会重症医学分会和《中华创伤杂志》编辑委员会组织相关专家,以国务院联防联控机制方案为政策依据,基于国际疫情大流行3年来sTBI和COVID-19的国内外文献,制订《重型创伤性脑损伤合并新型冠状病毒感染成人患者临床诊疗中国专家共识(2023版)》。本共识从急诊处理、急诊手术和病房综合管理等方面提出15条推荐建议,为sTBI合并COVID-19患者的诊断和治疗提供指导。

关键词：冠状病毒属脑损伤,创伤性专家共识

Chemoprophylaxis, diagnosis, treatments, and discharge management of COVID-19: An evidence-based clinical practice guideline(updated version)

在线全文

学校读者我要写书评

暂无评论

Military Medical Research 2020年第3期7卷 249-282页

作者： Ying-Hui Jin Qing-Yuan Zhan Zhi-Yong Peng Xue-Qun Ren Xun-Tao Yin Lin Cai Yu-Feng Yuan Ji-Rong Yue Xiao-Chun Zhang Qi-Wen Yang Jianguang Ji Jian Xia Yi-Rong Li Fu-Xiang Zhou Ya-Dong Gao Zhui Yu Feng Xu Ming-Li Tu Li-Ming Tan Min Yang Fang Chen Xiao-Ju Zhang Mei Zeng Yu Zhu Xin-Can Liu Jian Yang Dong-Chi Zhao Yu-Feng Ding Ning Hou Fu-Bing Wang Hao Chen Yong-Gang Zhang Wei Li Wen Chen Yue-Xian Shi Xiu-Zhi Yang Xue-Jun Wang Yan-Jun Zhong Ming-Juan Zhao Bing-Hui Li Lin-Lu Ma Hao Zi Na Wang Yun-Yun Wang Shao-Fu Yu Lu-Yao Li Qiao Huang Hong Weng Xiang-Ying Ren Li-Sha Luo Man-Ru Fan Di Huang Hong-Yang Xue Lin-Xin Yu Jin-Ping Gao Tong Deng Xian-Tao Zeng Hong-Jun Li Zhen-Shun Cheng Xiao-Mei Yao Xing-Huan Wang Center for Evidence-Based and Translational Medicine Zhongnan Hospital of Wuhan UniversityWuhan 430071China National Clinical Research Center for Respiratory Diseases China-Japan Friendship HospitalBeijing 100029China Department of Pulmonary and Critical Care Medicine China-Japan Friendship HospitalBeijing 10029China Leishenshan Hospital in Wuhan Wuhan 430200China Department of Critical Care Medicine Zhongnan Hospital of Wuhan UniversityWuhan 430071China institutes of Evidence-based Medicine and Knowledge Translation Henan UniversityKaifeng 475000HenanChina Department of Medical Imaging Guizhou Provincial People’s HospitalGuiyang 550002China Departments of Orthopedics Zhongnan Hospital of Wuhan UniversityWuhan 430071China Department of Hepatobiliary Surgery Zhongnan Hospital of Wuhan UniversityWuhan 430071China National Clinical Research Center for Geriatrics West China Hospital of Sichuan UniversityChengdu 610041China Department of Geriatrics West China Hospital of Sichuan UniversityChengdu 610041China Department of Radiology Zhongnan Hospital of Wuhan UniversityWuhan 430071China Department of Clinical Laboratory Peking Union Medical College Hospital(PUMCH)Peking Union Medical CollegeChinese Academy of Medical Sciences(CAMS)Beijing 100730China Center for Primary Health Care Research Lund University and Region Skåne25002 MalmöSweden Emergency Center Zhongnan Hospital of Wuhan UniversityWuhan 403371China Department of Allergology Zhongnan Hospital of Wuhan UniversityWuhan 430071China Department of Radiation and Medical Oncology Zhongnan Hospital of Wuhan UniversityWuhan 43071China Department of Critical Care Medicine Renmin Hospital of Wuhan UniversityWuhan 430060China Department of Emergency Medicine and Chest Pain Center Qilu Hospital of Shandong UniversityJinan 250002China Department of Respiratory and Critical Care Medicine Suizhou Central HospitalHubei University of MedicineSuizhou 441300HubeiChina Department of Clinic Pharmacy Second People’s Hospital of Huaihua Ci

The novel severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is the cause of a rapidly spreading illness,coronavirus disease 2019(COVID-19),affecting more than seventeen million people around the *** and treatment guidelines for clinicians caring for patients are *** the early stage,we have issued"A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus(2019-nCoV)infected pneumonia(standard version)";now there are many direct evidences emerged and may change some of previous recommendations and it is ripe for develop an evidence-based *** formed a working group of clinical experts and *** steering group members proposed 29 questions that are relevant to the management of COVID-19 covering the following areas:chemoprophylaxis,diagnosis,treatments,and discharge *** searched the literature for direct evidence on the management of COVID-19,and assessed its certainty generated recommendations using the Grading of Recommendations,Assessment,Development and Evaluation(GRADE)*** were either strong or weak,or in the form of ungraded consensus-based ***,we issued 34 *** them,6 were strong recommendations for,14 were weak recommendations for,3 were weak recommendations against and 11 were ungraded consensus-based *** covered topics of chemoprophylaxis(including agents and Traditional Chinese Medicine(TCM)agents),diagnosis(including clinical manifestations,reverse transcription-polymerase chain reaction(RT-PCR),respiratory tract specimens,IgM and IgG antibody tests,chest computed tomography,chest X-ray,and CT features of asymptomatic infections),treatments(including lopinavirritonavir,umifenovir,favipiravir,interferon,remdesivir,combination of antiviral drugs,hydroxychloroquine/chloroquine,interleukin-6 inhibitors,interleukin-1 inhibitors,glucocorticoid,qingfei paidu decoction,lianhua qingwen granules/capsules,convalescent plasma,lung

关键词： COVID-19 SARS-CoV-2 Recommendation Chemoprophylaxis Diagnosis Treatment Discharge management Traditional Chinese medicine guideline