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Evaluation of Anti-Hyperglycemic and Anti-Hyperlipidemic Activities of Water Kefir as Probiotic on Streptozotocin-Induced Diabetic Wistar Rats

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Journal of Diabetes Mellitus 2014年第2期4卷 85-95页

作者： Muneer Alsayadi Yaser Al Jawfi meriem Belarbi Zoubida Soualem-Mami Hafida Merzouk Daoudi Chaban Sari Fatima Sabri meriem ghalim Department of Food Science and Technology Faculty of agricultureIbb UniversityIbbYemen Laboratory of Natural Products Department of BiologyFaculty of Natural and Life SciencesEarth andUniverseUniversity of Abou-Bekr BelkaidTlemcenAlgeria Department of Food Safety Station of Agriculture ResearchesSana’aYemen Laboratory of Physiology Physiopathology and Biochemistry of NutritionDepartment of BiologyFaculty of Natural and Life SciencesEarth and UniverseUniversity of Abou-Bekr BelkaidTlemcenAlgeria

Diabetes mellitus is a predominant chronic disease which causes mortality of millions of people yearly. Its prevalence is on the rise worldwide. Water kefir is fermented food produced by a matrix of polysaccharides containing bacteria and yeasts, with therapeutic properties. Our study aimed to evaluate anti-hyperglycemic and anti-hyperlipidemic activities of water kefir on streptozotocin-induced diabetic Wistar rats. Adult Wistar rats were made diabetic by intraperitoneal injection of streptozotocin, and were given or not kefir in drinking water for 5 weeks. Body weight, glucose and lipid levels were measured. The results demonstrated evident improvement in body weight, glucose, and lipid profiles of treated rats comparing with diabetic or control rats. Water kefir is found to be less cost hypoglycemic and hypolipidimic treatment and less time consuming. Water kefir can potentially be useful food for diabetes to control glucose and lipid levels.

关键词： Component Formatting Style Styling Anti-Hyperglycemic Anti-Hyperlipidaemic Water Kefir Diabetes Wistar Rat

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Cheesy material on macroscopic on-site evaluation after endoscopic ultrasound-guided fine-needle biopsy:Don't miss the tuberculosis

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World Journal of Clinical Cases 2023年第10期11卷 2181-2188页

作者： Hanane Delsa Khadija Bellahammou Hussein Hassan Okasha Fahd ghalim Department of Gastroenterology and Hepatology Cheikh Khalifa International University HospitalMohammed VI University of Sciences and HealthCasablanca 82403Morocco Department of Oncology Tetouan HospitalTetouan 93000Morocco Department of Internal Medicine Division of GastroenterologyHepatology and EndoscopyKasr Al-Ainy School of MedicineCairo universityCairo 11562Egypt

Endoscopic ultrasound-guided fine-needle biopsy(EUS-FNB)is an excellent investigation to diagnose pancreatic lesions and has shown high accuracy for its use in pathologic ***,macroscopic on-site evaluation(MOSE)performed by an endoscopist was introduced as an alternative to rapid on-site cytologic evaluation to increase the diagnostic yield of *** MOSE of the biopsy can estimate the adequacy of the sample directly by the macroscopic evaluation of the core tissue obtained from *** pancreatic tuberculosis is extremely rare and difficult to diagnose because of its non-specific signs and ***,this challenging diagnosis is based on endoscopy,imaging,and the bacteriological and histological examination of tissue *** uncommon presentation of tuberculosis can be revealed as pancreatic mass mimicking ***-FNB can be very useful in providing a valuable histopathological diagnosis.A calcified lesion with a cheesy core in MOSE must be suggestive of tuberculosis,leading to the request of the GeneXpert,which can detect Mycobacterium tuberculosis deoxyribonucleic acid and resistance to rifampicin.A decent diagnostic strategy is crucial to prevent unnecessary surgical resection and to supply conservative management with antitubercular therapy.

关键词： Pancreatic tuberculosis Endoscopic ultrasound Fine-needle biopsy Macroscopic on-site evaluation Cheesy material GeneXpert

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Role of endoscopic ultrasound in the characterization of solid pseudopapillary neoplasm of the pancreas

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World Journal of Gastrointestinal Endoscopy 2023年第4期15卷 273-284页

作者： Katarzyna M Pawlak Nadeem Tehami Ben Maher Shujaath Asif Krishn Kant Rawal Daniel Vasile Balaban Mohammed Tag-Adeen Fahd ghalim Wael A Abbas Elsayed Ghoneem Khaled Ragab Mahmoud El-Ansary Shanil Kadir Sunil Amin Keith Siau Anna Wiechowska-Kozlowska Klaus Mönkemüller Dalia Abdelfatah Abeer Abdellatef Sundeep Lakhtakia Hussein Hassan Okasha Endoscopy Unit Department of GastroenterologyHospital of The Ministry of Interior and AdministrationSzczecin 01-218Poland Interventional Endoscopy Unit University Hospital Southampton NHS Foundation Trust3AX POUnited Kingdom Consultant Gastroenterologist AIG HospitalsHyderabad 500032India Department of Gastroenterology Prime Institute of Digestive SciencesRajkot 360001India Department of Gastroenterology Central Military Emergency University HospitalCarol Davila University of Medicine and PharmacyBucharest 010011Romania Division of Gastroenterology and Hepatology Department of Internal MedicineQena Faculty of MedicineSouth Valley UniversityQena 83511Egypt Department of Endoscopy Shefa Al-Orman HospitalLuxor 85951Egypt Interventional Endoscopy Unit Sainte Marie HospitalOSNY 95520France Department of Internal Medicine Gastroenterology UnitFaculty of MedicineAssuit UniversityAssuit 71511Egypt Department of Gastroenterology and Hepatology Faculty of MedicineMansoura UniversityMansoura 35511Egypt Department of Hepatology and Gastroenterology Theodor Bilharz Research InstituteGiza 12511Egypt Department of Hepatology&Gastroenterology Theodor Bilharz Research InstituteGiza 12511Egypt Department of Gastroenterology Liaquat National Hospital&Medical CollegeKarachi 75900Pakistan

BACKGROUND Solid pseudopapillary neoplasm(SPN)is an uncommon pathology of the pancreas with unpredictable malignant *** ultrasound(EUS)assessment plays a vital role in lesion characterization and confirmation of the tissue ***,there is a paucity of data regarding the imaging assessment of these *** To determine the characteristic EUS features of SPN and define its role in preoperative *** This was an international,multicenter,retrospective,observational study of prospective cohorts from 7 large hepatopancreaticobiliary *** cases with postoperative histology of SPN were included in the *** collected included clinical,biochemical,histological and EUS *** One hundred and six patients with the diagnosis of SPN were *** mean age was 26 years(range 9 to 70 years),with female predominance(89.6%).The most frequent clinical presentation was abdominal pain(80/106;75.5%).The mean diameter of the lesion was 53.7 mm(range 15 to 130 mm),with the slight predominant location in the head of the pancreas(44/106;41.5%).The majority of lesions presented with solid imaging features(59/106;55.7%)although 33.0%(35/106)had mixed solid/cystic characteristics and 11.3%(12/106)had cystic *** was observed in only 4(3.8%)*** pancreatic duct dilation was uncommon,evident in only 2 cases(1.9%),whilst common bile duct dilation was observed in 5(11.3%)*** patient demonstrated a double duct sign at *** and Doppler evaluation demonstrated inconsistent appearances with no emergence of a predictable *** guided biopsy was performed using three different types of needles:Fine needle aspiration(67/106;63.2%),fine needle biopsy(37/106;34.9%),and Sonar Trucut(2/106;1.9%).The diagnosis was conclusive in 103(97.2%)***-seven patients were treated surgically(91.5%)and the post-surgical SPN diagnosis was confirmed in all *** the 2-year

关键词： Solid pseudopapillary neoplasm SPN Frantz tumor Endoscopic ultrasound features EUSguided biopsy Fine needle aspiration/biopsy

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