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Journal of Animal science and Biotechnology 2017年第2期8卷 391-404页

作者： sandra J.A.van Kuijk José C.del Río Jorge Rencoret Ana Gutiérrez Anton s.M.sonnenberg Johan J.P.Baars Wouter H.Hendriks John W.Cone Animal Nutrition Group Wageningen UniversityDe Elst 16708 WD WageningenThe Netherlands Instituto de Recursos Naturales y Agrobiologica de sevilla(IRNAs-CsIC) Avenida Reina Mercedes1042012 SevilleSpain Plant Breeding Wageningen UniversityDroevendaalsesteeg 16708 PB WageningenThe Netherlands

Background： The present work investigated the influence of lignin content and composition in the fungal treatment of lignocellulosic biomass in order to improve rumen degradability. Wheat straw and wood chips,differing in lignin composition, were treated with Lentinula edodes for 0, 2, 4, 8 and 12 wk and the changes occurring during fungal degradation were analyzed using pyrolysis-gas chromatography-mass spectrometry and detergent fiber ***： L. edodes preferentially degraded lignin, with only limited cellulose degradation, in wheat straw and wood chips, leaving a substrate enriched in cellulose. syringyl（s）-lignin units were preferentially degraded than guaiacyl（G）-lignin units, resulting in a decreased s/G ratio. A decreasing s/G ratio（wheat straw： r =-0.72, wood chips： r =-0.75） and selective lignin degradation（wheat straw： r =-0.69, wood chips： r =-0.88） were correlated with in vitro gas production（IVGP）, a good indicator for rumen ***： L. edodes treatment increased the IVGP of wheat straw and wood chips. Effects on IVGP were similar for wheat straw and wood chips indicating that lignin content and 3D-structure of cell walls influence in vitro rumen degradability more than lignin composition.

关键词： Fungal treatment In vitro rumen degradability Lignocellulosic biomass Py-GC/Ms

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Histological Analysis and Morphometric Changes after Autologous Fat Grafting in Large Volumes on Pigs

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mercedes-Benz车用柴油机钢活塞

Journal of Cosmetics, Dermatological sciences and Applications 2021年第4期

作者： Hector Giancarlo Torres-Nuño Walter Angel Trujillo-Rangel Jorge Barrera-Alcocer Miriam Méndez del Villar Diana mercedes Hernández-Corona sylvia Elena Totsuka-sutto Leonel García Benavides

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汽车与新动力 2016年第1期48卷 48-51页

作者： J.schommers V.Lagemann J.Bhm s.Binder 范明强

长期以来,钢活塞一直用于载货车用柴油机。2014年,Daimler公司作为最早的汽车制造商将钢活塞应用于轿车柴油机。现在钢活塞不仅用于Daimler公司OM626和OM607柴油机的传统灰铸铁气缸套曲轴箱,还首次用于OM642-V6柴油机全铝气缸体曲轴箱与... 详细信息

长期以来,钢活塞一直用于载货车用柴油机。2014年,Daimler公司作为最早的汽车制造商将钢活塞应用于轿车柴油机。现在钢活塞不仅用于Daimler公司OM626和OM607柴油机的传统灰铸铁气缸套曲轴箱,还首次用于OM642-V6柴油机全铝气缸体曲轴箱与"Nanoslide"气缸工作表面涂层的组合。

关键词：钢活塞铝活塞降低摩擦柴油机

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智能燃料电池—插电式混合动力系统

汽车与新动力 2020年第5期3卷 15-19页

作者： [德]C.MOHRDIECK [德]s.DEHN 范明强(译) 不详

Daimler公司搭载新款mercedes-Benz GLC F-Cell型燃料电池的新一代燃料电池汽车将投放市场。由于采用了全新的部件和配置,该车型比原车型更为高效和紧凑。同时,插电式混合动力技术、锂离子电池和精确的行驶程序有助于巩固其新能源汽车... 详细信息

Daimler公司搭载新款mercedes-Benz GLC F-Cell型燃料电池的新一代燃料电池汽车将投放市场。由于采用了全新的部件和配置,该车型比原车型更为高效和紧凑。同时,插电式混合动力技术、锂离子电池和精确的行驶程序有助于巩固其新能源汽车的市场地位。

关键词：燃料电池插电式混合动力锂离子电池

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Comparative study of breast cancer in Mexican and Mexican-American women

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Health 2010年第9期2卷 1040-1048页

作者： Maria Elena Martinez Luis Enrique Gutierrez-Millan Melissa Bondy Adrian Daneri-Navarro Maria mercedes Meza-Montenegro Ivan Anduro-Corona Ma Isabel Aramburo-Rubio Luz Maria Adriana Balderas-Pena Jose Adelfo Barragan-Ruiz Abenaa Brewster Graciela Caire-Juvera Juan Manuel Castro-Cervantes Mario Alberto Chavez Zamudio Giovanna Cruz Alicia Del Toro-Arreola Mary EEdgerton Maria Rosa Flores-Marquez Ramon Antonio Franco-Topete Helga Garcia susan Andrea Gutierrez-Rubio Karin Hahn Luz Margarita Jimenez-Perez Ian KKomenaka Zoila Areli Lopez Bujanda Dihui Lu Gilberto Morgan-Villela James LMurray Jesse NNodora Antonio Oceguera-Villanueva Miguel Angel Ortiz Martinez Laura Perez Michel Antonio Quintero-Ramos Aysegul sahin Jeong Yun shim Maureen stewart Gonzalo Vazquez-Camacho Betsy Wertheim Rachel Zenuk Patricia Thompson Arizona Cancer Center and Mel and Enid Zuckerman College of Public Health University of ArizonaTucsonUSA Departamento de Investigaciones Cientificas y Tecnologicas Universidad de SonoraHermosilloMexico University of Texas M.D.Anderson Cancer Center HoustonUSA Departamento de Fisiologia Centro Universitario de Ciencias de la SaludUniversidad de GuadalajaraGuadalajaraMexico Instituto Tecnologico de sonora Ciudad ObregónMexico Instituto Mexicano del seguro social HermosilloMexico Instituto Mexicano del seguro social CMNOGuadalajaraJalisco Centro de Investigacion en Alimentacion y Desarrollo HermosilloMexico Instituto Mexicano del seguro social Ciudad ObregonMexico OPD Hospital Civil de Guadalajara GuadalajaraMexico Departamento de salud Publica Centro Universitario de Ciencias de la SaludUniversidad de GuadalajaraGuadalajaraMexico Maricopa Medical Center Department of SurgeryPhoenixUSA University of North Carolina Lineberger Cancer CenterChapel HillUSA Arizona Cancer Center and Department of Family and Community Medicine University of ArizonaTucsonUSA Instituto Jalisciense de Cancerologia GuadalajaraMexico

Breast cancer is the number one cause of can- cer deaths among Hispanic women in the United states, and in Mexico, it recently became the primary cause of cancer deaths. This malign- nancy represents a poorly understood and un- derstudied disease in Hispanic women. The ELLA Binational Breast Cancer study was es- tablished in 2006 as a multi-center study to as- sess patterns of breast tumor markers, clinical characteristics, and their risk factors in women of Mexican descent. We describe the design and implementation of the ELLA study and provide a risk factor comparison between women in the U.s. and those in Mexico based on a sample of 765 patients (364 in the U.s. and 401 in Mexico). Compared to women in Mexico, U.s. women had significantly (p s. 3.9 mean live births) and breastfeeding rates (57.5% vs. 80.5%), higher use of oral contraceptives (60.7% vs. 50.1%) and hormone replacement therapy (23.3% vs. 7.6%), and higher family history of breast cancer (15.7% vs. 9.0%). Re- sults show that differences in breast cancer risk factor patterns exist between Mexico and U.s. women. We provide lessons learned from the conduct of our study. Binational studies are an important step in understanding disease pat- terns and etiology for women in both countries.

关键词： Binational study Breast Cancer Hispanics Mexico United states

Alterations of Blood Immune Cells in Elderly Patients with COVID-19 and with or without Pre-Existing Type 2 Diabetes

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Open Journal of Immunology 2022年第2期12卷 41-63页

作者： susana salva Yanina Kolling Nicolás Argañaraz María Pía Rocchia Novillo María del Milagro Rocchia Novillo Leonardo Albarracin Jacqueline Charubi Alejandra Casen Nadia Gobbato Mirta Rachid susana Alvarez Haruki Kitazawa Julio Villena Juan Carlos Valdez Laboratory of Immunobiotechnology Reference Centre for Lactobacilli (CERELA-CONICET) Tucuman Argentina Laboratory of Immunology Faculty of Biochemistry Chemistry and Pharmacy National University of Tucuman Tucuman Argentina Hospital Centro de salud “Zenon santillan” Tucuman Argentina Instituto de Maternidad “Ntra. sra. De las mercedes” Tucuman Argentina Food and Feed Immunology Group Laboratory of Animal Food Function Graduate School of Agricultural Science Tohoku University Sendai Japan Livestock Immunology Unit International Education and Research Center for Food and Agricultural Immunology (CFAI) Graduate School of Agricultural Science Tohoku University Sendai Japan

Elderly individuals, especially those with pre-existing conditions like type 2 diabetes mellitus (T2DM), have a high risk for developing severe cases of COVID-19. The aim of this work was to characterize the alterations of blood immune cells (BIC) in patients with symptomatic COVID-19 and confirmed sARs-CoV-2 infection, ≥60 years and who needed hospitalization in the Centro de salud Hospital of Tucuman, Argentina, during the second peak of the pandemic in Argentina. Ten patients were enrolled from December 2020 to May 2021. Blood samples were taken at the time of admission (day 0) and five days after (day 5) for routine laboratory tests and the characterization of BIC by flow cytometry. Most of the patients were men (70%) aged between 60 and 78 years. The 70% of patients had T2DM while 50% had arterial hypertension. At day 0, all the patients had increased neutrophils and inflammatory markers (C reactive protein and D-dimers) and reduced numbers of lymphocytes, HLA-DRsup>hisup> monocytes, CD16sup>+sup>CD56sup>+sup> NK cells, CD3sup>+sup>HLAsup>−sup>DRsup>+sup>CD25sup>+sup> cells, CD4sup>+sup> and CD8sup>+sup> T cells in blood. Patients received a standard treatment for COVID-19 care (Osub>2sub>, corticosteroids and antibiotics). The hospital treatment normalized the levels of BIC (day 5) in 30% of patients who were those with no comorbidities. In patients with T2DM, BIC recovery was variable. In T2DM patients who required administration of plasma (30%), prolonged Osub>2sub> therapy (40%) or referral to the intensive care unit (10%) significant reductions of CD16sup>+sup>CD56sup>+sup>, CD3sup>+sup>HLAsup>−sup>DRsup>+sup>CD25sup>+sup>, CD4sup>+sup> and CD8sup>+sup> cells were observed between days 0 and 5. In line with previous studies, our results show that absolute counts of major lymphocyte subsets in blood are significantly and substantially decreased during the course of severe COVID-19 disease

关键词： COVID-19 sARs-CoV-2 Diabetes Elderly Blood Leukocytes Immune Response

肝部分切除术理想的手术切口:mercedes型切口远期并发症较扩大右肋缘下切口增加

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中华肝胆外科杂志 2006年第8期12卷 573-573页

作者： D＇Angelica M Maddineni s Fong Y 黄辉不详解放军总医院第二附属医院北京市100091

　　该研究主要是对比肝部分切除术采用两种不同腹部切口的早期和远期并发症的不同.……

关键词：肝部分切除术远期并发症肋缘下切口手术切口理想腹部切口

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BAF和PRC2复合物亚基Dpf2和Eed拮抗调控Tbx3控制胚胎干细胞分化

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科学新闻 2020年第2期 62-62页

作者：张文胜 Constantinos Chronis 陈曦 Heyao Zhang Rapolas spalinskas mercedes Pardo Liangliang Chen 吴光明朱哲鑫余勇 Lu Yu Jyoti Choudhary Jennifer Nichols Mana M.Parast Boris Greber Pelin sahle'n Kathrin Plath 苏州大学医学部剑桥苏大基因组资源中心 sanger研究所马谱生物分子医学研究所伦敦癌症研究所剑桥大学干细胞研究所加州大学圣迭戈分校瑞典皇家理工学院加州大学洛杉矶分校

文章简介BAF(Brg or Brahma-associated factors)染色质重塑复合物利用其ATP酶亚基水解ATP产生的能量改变组蛋白和DNA的作用,调控转录因子同DNA的结合而调节基因的表达,参与多种生物学过程。BAF复合物由多至15个不同的亚基组成,但对这... 详细信息

文章简介BAF(Brg or Brahma-associated factors)染色质重塑复合物利用其ATP酶亚基水解ATP产生的能量改变组蛋白和DNA的作用,调控转录因子同DNA的结合而调节基因的表达,参与多种生物学过程。BAF复合物由多至15个不同的亚基组成,但对这些亚基功能的研究多局限于显示失活特定亚基而导致的表型缺陷,缺乏深入的作用机制的研究。

关键词：干细胞分化 Eed 复合物 BAF

Comparative study of breast cancer in Mexican and Mexican-American women

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