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Multiple grain-size fraction analysis of heavy minerals and the provenance identification of sediments from the abandoned Huanghe River,eastern China

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Journal of Oceanology and Limnology 2023年第3期41卷 921-935页

作者： mengyao wang Bingfu JIN Jianjun JIA State Key Laboratory of Estuarine and Coastal Research East China Normal UniversityShanghai 200241China School of Resources and Environmental Engineering Ludong UniversityYantai 264025China

The quantitative analysis of sediment sources in a sink is an important scientific topic and challenge in provenance *** characteristics of heavy minerals,combined with the geochemical constituents of detrital grains,provide a reliable provenance-tracing *** developed a mineral identification method to analyze the multiple grain-size fraction of sediments,from which the elemental geochemistry of hornblende was used to compare the characteristics of sediments from the Huaihe River and Huanghe(Yellow)River in eastern *** that were statistically identified as being able to discriminate sediment provenance were employed to perform a quantitative analysis of the sources of sediments of the abandoned Huanghe *** reveal that the Huaihe River is characterized by a high amphibole content of>60%and that the Huanghe and abandoned Huanghe rivers have greater abundances of limonite and carbonate minerals compared with those of the Huaihe *** contents of trace elements and rare earth elements in hornblende show that the sediments of the abandoned Huanghe River are similar to those of the Huanghe River but different from those of the Huaihe ***,chemical mass balance was used to calculate the relative contributions of different provenances of sediment from the abandoned Huanghe River,and nine trace elements of hornblende were identified as discriminators of *** 2%of the hornblende in the abandoned Huanghe River is derived from the Huaihe River and 98%from the Huanghe *** the proportion of hornblende in the total sediment,it is inferred that the contribution of Huaihe River sediment to the abandoned Huanghe River is approximately 0.5%.This study shows that mineral analysis using multiple grain-size fractions(within the wide range of 1Φto 6Φ)with assessment in elemental geochemistry of hornblende can characterize the provenance of fluvial material in coastal zones.

关键词： quantitative provenance analysis heavy mineral multiple grain-size fraction hornblende elemental geochemistry fluvial sediment the abandoned Huanghe River

SNR Improvement of QEPAS System by Preamplifier Circuit Optimization and Frequency Locked Technique

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Photonic Sensors 2018年第2期8卷 127-133页

作者： Qinduan ZHANG Jun CHANG Zongliang wang Fupeng wang Fengting JIANG mengyao wang School of Information Science and Engineering and Shandong Provincial Key Laboratory of Laser Technology and Application Shandong University Jinan 250100 China School of Physics Science and Information Technology and Shandong Key Laboratory of Optical Communication Science and Technology Liaocheng University Liaocheng 252059 China

Preamplifier circuit noise is of great importance in quartz enhanced photoacoustic spectroscopy （QEPAS） system. In this paper, several noise sources are evaluated and discussed in detail. Based on the noise characteristics, the corresponding noise reduction method is proposed. In addition, a frequency locked technique is introduced to further optimize the QEPAS system noise and improve signal, which achieves a better performance than the conventional frequency scan method. As a result, the signal-to-noise ratio （SNR） could be increased 14 times by utilizing frequency locked technique and numerical averaging technique in the QEPAS system for water vapor detection.

关键词： QEPAS system preamplifier circuit frequency locked method noise optimization

Seasonal Variations of Observed Raindrop Size Distribution in East China

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Advances in Atmospheric Sciences 2019年第4期36卷 346-362页

作者： Long WEN Kun ZHAO mengyao wang Guifu ZHANG Key Laboratory of Mesoscale Severe Weather of Ministry of Education and School of Atmospheric Sciences Nanjing University State Key Laboratory of Severe Weather and Joint Center for Atmospheric Radar Research of China Meteorological Administration and Nanjing University Chinese Academy of Meteorological Sciences Xichang Satellite Launch Center School of Meteorology and Center for Analysis and Prediction of Storms University of Oklahoma

Seasonal variations of rainfall microphysics in East China are investigated using data from the observations of a twodimensional video disdrometer and a vertically pointing micro rain radar. The precipitation and rain drop size distribution(DSD) characteristics are revealed for different rain types and seasons. Summer rainfall is dominated by convective rain,while during the other seasons the contribution of stratiform rain to rainfall amount is equal to or even larger than that of convective rain. The mean mass-weighted diameter versus the generalized intercept parameter pairs of convective rain are plotted roughly around the "maritime" cluster, indicating a maritime nature of convective precipitation throughout the year in East China. The localized rainfall estimators, i.e., rainfall kinetic energy–rain rate, shape–slope, and radar reflectivity–rain rate relations are further derived. DSD variability is believed to be a major source of diversity of the aforementioned derived estimators. These newly derived relations would certainly improve the accuracy of rainfall kinetic energy estimation, DSD retrieval, and quantitative precipitation estimation in this specific region.

关键词： raindrop size distribution precipitation microphysics disdrometer seasonal variation East China

Development of a cell adhesion-based prognostic model for multiple myeloma:Insights into chemotherapy response and potential reversal of adhesion effects

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Oncology Research 2024年第4期32卷 753-768页

作者： QIAN HU mengyao wang JINJIN wang YALI TAO TING NIU Department of Hematology West China HospitalSichuan UniversityChengdu610041China

Multiple myeloma(MM)is a hematologic malignancy notorious for its high relapse rate and development of drug resistance,in which cell adhesion-mediated drug resistance plays a critical *** study integrated four RNA sequencing datasets(CoMMpass,GSE136337,GSE9782,and GSE2658)and focused on analyzing 1706 adhesionrelated *** univariate Cox regression analysis identified 18 key prognosis-related genes,including KIF14,TROAP,FLNA,MSN,LGALS1,PECAM1,and ALCAM,which demonstrated the strongest associations with poor overall survival(OS)in MM *** comprehensively evaluate the impact of cell adhesion on MM prognosis,an adhesion-related risk score(ARRS)model was constructed using Lasso Cox regression *** ARRS model emerged as an independent prognostic factor for predicting ***,our findings revealed that a heightened cell adhesion effect correlated with tumor resistance to DNA-damaging drugs,protein kinase inhibitors,and drugs targeting the PI3K/Akt/mTOR signaling ***,we identified promising drug candidates,such as tirofiban,pirenzepine,erlotinib,and bosutinib,which exhibit potential in reversing this *** vitro,experiments employing NCIH929,RPMI8226,and AMO1 cell lines confirmed that MM cell lines with high ARRS exhibited poor sensitivity to the aforementioned candidate *** employing siRNA-mediated knockdown of the key ARRS model gene KIF14,we observed suppressed proliferation of NCIH929 cells,along with decreased adhesion to BMSCs and *** study presents compelling evidence establishing cell adhesion as a significant prognostic factor in ***,potential molecular mechanisms underlying adhesion-related resistance are proposed,along with viable strategies to overcome such *** findings provide a solid scientific foundation for facilitating clinically stratified treatment of MM.

关键词： Cell adhesion Bioinformatics Prognosis Multiple myeloma CAM-DR

Black tantalic oxide submicro-particles coating on PEEK fibers woven into fabrics as artificial ligaments with photothermal antibacterial effect and osteogenic activity for promoting ligament-bone healing

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Journal of Materials Science & Technology 2023年第2期133卷 195-208页

作者： Fan wang mengyao wang Qingsong He Xuehong wang Ping Sun Yinjun Ji Yunfei Niu Fengqian Li Jie Wei Shanghai Key Laboratory of Advanced Polymeric Materials School of Materials Science and EngineeringKey Laboratory for Ultrafine Materials of Ministry of EducationEast China University of Science and TechnologyShanghai 200237China Department of Orthopaedics Shanghai Eighth People’s HospitalShanghai 200235China Department of Orthopaedics Changhai HospitalSecond Military Medical UniversityShanghai 200433China

Design of artificial ligaments possessing both osteogenic activity and antibacterial effect that promotes ligament-bone healing and prevents bacterial infection in bone tunnels for anterior cruciate ligament(ACL)reconstruction remains a significant *** this study,black tantalic oxide(BTO)submicro-particles with oxygen vacancies and structure defects were fabricated by using traditional white tan-talic oxide(WTO)through magnesium thermal reduction(MTR)method,and BTO was coated on polyetheretherketone(PEEK)fibers(PKF),which were woven into fabrics(PBT)as artificial *** with BTO coating exhibited excellent photothermal performance,which possessed not only antibac-terial effects in vitro but also anti-infective ability in *** with optimized surface properties(e.g.,submicro-topography and hydrophilicity)not only significantly facilitated rat bone mesenchymal stem cells(BMSC)responses(e.g.,proliferation and osteogenic differentiation)in vitro but also stimulated new bone formation for ligament-bone healing in *** presence of oxygen vacancies and structure de-fects in BTO did not change the surface properties and osteogenic activity of BPT while displaying an outstanding photothermal antibacterial *** summary,BPT with osteogenic activity and photother-mal antibacterial effect promoted bone regeneration and prevented bacterial infection,thereby promoting ligament-bone ***,PBT would have tremendous potential as a novel artificial ligament for ACL reconstruction.

关键词： Black tantalic oxide PEEK fibers Artificial ligament Photothermal antibacterial effects Ligament-bone healing

Mode hopping and polarization switching of mutually coupled vertical-cavity surface-emitting lasers

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Science in China(Series F) 2008年第5期51卷 592-598页

作者： ZHANG WeiLi PAN Wei LUO Bin wang mengyao ZOU XiHua School of Information Science and Technology Southwest Jiaotong University Chengdu 610031 China

We perform a theoretical study on the polarization-resolved compound lasing mode （CLM） of two mutually coupled vertical-cavity surface-emitting lasers （VCSELs）. Different solutions of CLMs are derived though stability analysis of the spin-flip model. The dynamical evolvements of CLMs with the existence of polarization degrees of freedom are also charactered. The most stable CLM with the smallest carrier density tend to be excited, since the gain needed for this mode to emit is the lowest. In the given system, varying values of injection rate or birefringence, etc., will change the generation of the preferred CLMs in the two polarization directions, and thus influence the polarization switching （PS） characteristics. Thus, hoppings between CLMs are also companied by PSs. Through mapping of average power in the parameter space, the influences of coupling rate and anisotropy parameters （linear dichroism and linear birefringence） on PS and hopping between CLMs are discussed.

关键词： vertical-cavity surface-emitting semiconductor laser polarization switching mutual injection mode hopping

Detecting gravitational wave with an interferometric seismometer array on lunar nearside

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Science China(Physics,Mechanics & Astronomy) 2023年第10期66卷 203-223页

作者： Junlang Li Fangfei Liu Yuan Pan Zijian wang Mengdi Cao mengyao wang Fan Zhang Jinhai Zhang Zong-Hong Zhu Department of Astronomy Beijing Normal UniversityBeijing 100875China Advanced Institute of Natural Sciences Beijing Normal University at ZhuhaiZhuhai 519087China Institute for Frontiers in Astronomy and Astrophysics Beijing Normal UniversityBeijing 102206China Engineering Laboratory for Deep Resources Equipment and Technology Institute of Geology and Geophysics Chinese Academy of SciencesBeijing 100029China

Our Moon is by far the easiest natural, extraterrestrial celestial object for us to reach, and many space agencies, in particular the China National Space Administration, have publicized plans for manned missions there. Such high-profile projects must yield commensurate scientific outputs to justify their cost to the taxpayers. An important criterion for the selection of candidate experiments is the extent to which the Moon plays an integral and irreplaceable role, as opposed to offering only marginal advantages over Earth-orbit, space-based alternatives. In this study, we propose an experiment that excels in this regard, which considers the Moon as part of the experimental apparatus. Specifically, the Moon acts as a Weber bar-style resonant mass that responds to deci-Hertz gravitational waves(GWs). GW-excited lunar vibrations can be picked up by an array of(prefabricated on Earth and easy to transport to the Moon) small laser interferometric seismometers yielding GW detection. Such a setup would plug a gap in the GW frequency range already covered by the existing or underdevelopment detectors, and it can inform us on important astrophysics topics, such as the progenitors of Type Ia supernovae(SNe Ia) or intermediate mass black holes. We provide the instrument design as well as its deployment strategy, and we also summarize relevant science cases according to the estimated viable sensitivity.

关键词： gravitational waves lunar antenna seismic motion

Dispersion suppression scheme for Mach-Zehnder interferometer based interleaver using phase shifter

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High Technology Letters 2006年第1期12卷 10-13页

作者：邹喜华 Pan Wei Luo Bin Qin Zhangmiao Zhang Weili wang mengyao School of Computer and Communication Engineering Southwest Jiaotong University Chengdu 610031 P.R. China

To suppress the dispersion effect, an improved scheme was proposed for Mach-Zehnder intefferometer （MZI） based interleaver. The device consists of an MZI, a fiber loop （FL）, and a phase shifter inserted in FL. The introduction of π phase shifter into FI, dramatically suppresses the dispersion effiect. Then the transmission response remains square-like shape, with low frequency deviation and high extinction ratio. Moreover, the lower frequency deviation is achieved by reducing the dispersion coefficient. For 100GHz-spacing interleaver, the 0.08nm deviation is reduced to 0.02nm by replacing G.652 with G.655.

关键词： interleaver Mach-Zehnder interferometer (MZI) dispersion effect phase shifter

An overview of detecting gene-trait associations by integrating GWAS summary statistics and eQTLs

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Science China(Life Sciences) 2024年第6期67卷 1133-1154页

作者： Yang Zhang mengyao wang Zhenguo Li Xuan Yang Keqin Li Ao Xie Fang Dong Shihan wang Jianbing Yan Jianxiao Liu National Key Laboratory of Crop Genetic Improvement Huazhong Agricultural UniversityWuhan 430070China Key Laboratory of Smart Farming for Agricultural Animals Huazhong Agricultural UniversityWuhan 430070China Hubei Key Laboratory of Agricultural Bioinformatics Huazhong Agricultural UniversityWuhan 430070China College of Informatics Huazhong Agricultural UniversityWuhan 430070China College of Life Sciences Nankai UniversityTianjin 300071China

Detecting genes that affect specific traits(such as human diseases and crop yields)is important for treating complex diseases and improving crop quality.A genome-wide association study(GWAS)provides new insights and directions for understanding complex traits by identifying important single nucleotide *** GWAS summary statistics data related to various complex traits have been gathered *** have shown that GWAS risk loci and expression quantitative trait loci(e QTLs)often have a lot of overlaps,which makes gene expression gradually become an important intermediary to reveal the regulatory role of *** this review,we review three types of gene-trait association detection methods of integrating GWAS summary statistics and e QTLs data,namely colocalization methods,transcriptome-wide association study-oriented approaches,and Mendelian randomization-related *** the theoretical level,we discussed the differences,relationships,advantages,and disadvantages of various algorithms in the three kinds of gene-trait association detection *** further discuss the performance of various methods,we summarize the significant gene sets that influence highdensity lipoprotein,low-density lipoprotein,total cholesterol,and triglyceride reported in 16 *** discuss the performance of various algorithms using the datasets of the four lipid *** advantages and limitations of various algorithms are analyzed based on experimental results,and we suggest directions for follow-up studies on detecting gene-trait associations.

关键词： gene-trait association GWAS eQTL colocalization transcriptome-wide association study(TWAS) Mendelian randomization(MR)