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A genome-wide analysis of the chloroplast NADH dehydrogenase - like genes in Zostera marina

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Journal of Oceanology and Limnology 2022年第2期40卷 656-677页

作者： Mingyu MA Mingyu ZHONG Quansheng ZHANG Wei ZHAO mengxin wang Chengying LUO Bin XU Ocean School Yantai UniversityYantai 264005China

The chloroplast NADH dehydrogenase-like(NDH)complex,homologous to respiratory complex I,participates in photosystem I cyclic electron flow(PSI-CEF)and chlororespiration in *** analyses indicated that Zostera marina,a widely distributed seagrass,has a complete NDH complex,which is rarely observed in marine *** identified all 31 ndh genes necessary for the functional NDH complex,of which ndhB and pnsb3 occurred as duplication *** structural analyses of antiporter-like subunits showed that the long amphipathic helix of NdhF was lost in ***,which could exhibit an alternative mode in the generation of trans-thylakoid proton *** splicing pattern of ndh exhibited tissue-specific patterns and responded to light *** editing in *** presented the ancestral pattern with many of the primitive editing sites and *** partial editing in ndhF reflected the link between light stress and RNA ***,the predominant expression in leaves of most ndh genes suggested that their major function is in *** quantitative real time-PCR results show that the expression of ndh was signifi cantly upregulated in response to light ***,there were two diverse responsive mechanisms of the NDH complex in PSI-CEF and ***,the presence of a complete structure,upregulated gene expression level,and multiple post-transcriptional regulations could provide a molecular basis for the powerful NDH complex and enable *** to maintain eff ective photosynthetic performance.

关键词： Zostera marina NADH dehydrogenase-like complex genome-wide analysis profi les of expression

Insight into the effect of geographic location and intercropping on contamination characteristics and exposure risk of phthalate esters(PAEs)in tea plantation soils

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Journal of Integrative Agriculture 2024年第11期23卷 3896-3911页

作者： Jie Li Shanjie Han Ruhang Xu Xuchen Zhang Junquan Liang mengxin wang Baoyu Han Zhejiang Provincial Key Laboratory of Biometrology and Inspection and Quarantine College of Life SciencesChina Jiliang UniversityHangzhou 310018China Hangzhou Tea&Chrysanthemum Technology Co.Ltd.Hangzhou 310018China

Phthalate esters(PAEs)are an emerging pollutant due to widespread distribution in environmental mediums that have attracted widespread attention over recent ***,there is little information about tea plantation soil PAEs.A total of 270 soil samples collected from 45 tea plantations in the major high-quality tea-producing regions of Jiangsu,Zhejiang,and Anhui provinces in China were analyzed for seven *** detection frequency of PAEs in tea plantation soil was 100%.DBP,DEHP,and DiBP were the main congeners in tea plantation *** PAEs concentrations in the upper soil were significantly higher than those in the lower *** concentration of tea plantation soil PAEs in Jiangsu Province was significantly lower than those in Zhejiang and Anhui *** with chestnuts can effectively reduce the contamination level of PAEs in tea plantation *** analysis,redundancy analysis,partial correlation analysis,and structural equation modeling methods further confirmed the strong direct influence of factors such as chestnut–tea intercropping,temperature,and agricultural chemicals on the variation of PAEs in tea plantation *** health and ecological risk assessments indicated that non-carcinogenic risk was within a safe range and that there was a high carcinogenic risk via the dietary pathway,with DBP posing the highest ecological risk.

关键词： phthalate esters chestnut and tea intercropping driving factors spatial heterogeneity risk assessment

Potentials of ribosomopathy gene as pharmaceutical targets for cancer treatment

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Journal of Pharmaceutical Analysis 2024年第3期14卷 308-320页

作者： mengxin wang Stephen Vulcano Changlu Xu Renjian Xie Weijie Peng Jie wang Qiaojun Liu Lee Jia Zhi Li Yumei Li Key Laboratory of Biomaterials and Biofabrication in Tissue Engineering of Jiangxi Province Gannan Medical UniversityGanzhouJiangxi341000China School of Rehabilitation Medicine Gannan Medical UniversityGanzhouJiangxi341000China Autoimmunity and Inflammation Program HSS Research InstituteHospital for Special Surgery New YorkNew YorkNY10021USA Division of Oral and Systemic Health Sciences School of DentistryUniversity of CaliforniaLos AngelesCA90095USA School of Medical Information Engineering Gannan Medical UniversityGanzhouJiangxi341000China Inflammation and Immune Mediated Diseases Laboratory of Anhui Province Anhui Institute of Innovative DrugsInstitute for Liver Diseases of Anhui Medical UniversitySchool of PharmacyAnhui Medical UniversityHefei230032China School of Basic Medicine Gannan Medical UniversityGanzhouJiangxi341000China Institute of Oceanography Minjiang UniversityFuzhou350108China

Ribosomopathies encompass a spectrum of disorders arising from impaired ribosome biogenesis and reduced *** or dysexpression of the genes that disturb any finely regulated steps of ribosome biogenesis can result in different types of ribosomopathies in clinic,collectively known as ribosomopathy *** data suggest that ribosomopathy patients exhibit a significantly heightened susceptibility to *** ribosome biogenesis and dysregulation of some ribosomopathy genes have also been found to be intimately associated with cancer *** correlation between ribosome biogenesis or ribosomopathy and the development of malignancies has been well *** work aims to review the recent advances in the research of ribosomopathy genes among human cancers and meanwhile,to excavate the potential role of these genes,which have not or rarely been reported in cancer,in the disease development across *** plan to establish a theoretical framework between the ribosomopathy gene and cancer development,to further facilitate the potential of these genes as diagnostic biomarker as well as pharmaceutical targets for cancer treatment.

关键词： Ribosome biogenesis Ribosomopathy gene Cancer treatment target Pharmaceutical target

Effects of solid-state fermentation product of yeast supplementation on liver and intestinal health,and resistance of common carp(Cyprinus carpio)against spring viraemia carp virus

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Animal Nutrition 2024年第3期18卷 408-418页

作者： mengxin wang Dongmei Xia Lijuan Yu Qiang Hao Mingxu Xie Qingshuang Zhang Yajie Zhao Delong Meng Yalin Yang Chao Ran Tsegay Teame Zhen Zhang Zhigang Zhou China-Norway Joint Lab on Fish Gut Microbiota Institute of Feed ResearchChinese Academy of Agricultural SciencesBeijing 100081China Hubei Key Laboratory of Animal Nutrition and Feed Science Wuhan Polytechnic UniversityWuhan 430000China Key Laboratory for Feed Biotechnology of the Ministry of Agriculture and Rural Affairs Institute of Feed ResearchChinese Academy of Agricultural SciencesBeijing 100081China Tigray Agricultural Research Institute Mekelle Agricultural Research CenterMekelleTigray 251Ethiopia

This study aimed to investigate the effects of solid-state fermentation products of yeast(SFPY)on liver and intestinal health and disease resistance of common carp(Cyprinus carpio).A total of 200 common carp with an initial average weight of 2.55±0.004 g were divided into 5 groups(4 replications per group and 10 fish per replication),and were fed with one of five diets,including a control diet and 4 diets supplemented with 2‰(Y2),3‰(Y3),4‰(Y4),or 5‰(Y5)SFPY,respectively,for 8 *** indicated that,the addition of SFPY to the diet of common carp did not affect the growth performance or survival rate of fish(P=0.253).Interestingly,with the addition of SFPY,the triacylglycerol(TAG)content of the liver presented a linear decreasing tendency(P=0.004),with significantly decreased in Y4 and Y5 groups(P=0.035)compared with *** lipopolysaccharide(LPS)content and diamine oxidase(DAO)activity presented a negative linear relationship with the addition of SFPY(P=0.015,P=0.030),while serum lipopolysaccharide binding protein(LBP)content first decreased and then increased(P<0.001).The total antioxidant capacity(T-AOC)in the intestine of fish increased continuously with increasing SFPY supplementation(P=0.026),reaching the highest level in Y5 *** villus height in all experimental groups were significantly higher than that in the control group(P<0.001).Furthermore,compared to the control,adding 3‰SFPY to the control diet of common carp significantly increased the relative abundance of Fusobacteria(P=0.018)and decreased that of Proteobacteria(P=0.039)at phylum level,and increased the relative abundance of Cetobacterium(P=0.018)and decreased that of Shewanella(P=0.013)at genus *** with the control,the relative mRNA expression level of spring viraemia of carp virus N protein(SVCV-n)in the kidney was lower than that of the control group without significance and bottomed out in Y4 group(P=0.138).In conclusion,dietary SFPY enhanced the SVCV resistance capa

关键词： Yeast Solid-state fermentation product Probiotic Immunity Gut microbiota Common carp

A New Fiber Detection Method for LAMOST Based on the Front-illuminated Method

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Research in Astronomy and Astrophysics 2022年第6期22卷 42-51页

作者： Ming Zhou Yong Zhang Guanru Lv Jian Li Zengxiang Zhou Zhigang Liu Jianping wang Zhongrui Bai Yuan Tian mengxin wang Shuqing wang Hongzhuan Hu Chao Zhai Jiaru Chu Zhijie Han Mingxu Liu Yiqiao Dong Hailong Yuan Yongheng Zhao Yaoquan Chu Haotong Zhang Key Laboratory of Optical Astronomy National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100101China University of Chinese Academy of Sciences Beijing 100049China National Astronomical Observatories/Nanjing Institute of Astronomical Optics&Technology Chinese Academy of SciencesNanjing 210042China University of Science and Technology of China Hefei 230026China

The double revolving fiber positioning technology is one of the key technologies for the success of the Large Sky Area Multi-Object Fiber Spectroscopic Telescope(LAMOST).The accuracy of fiber positioning will directly affect the observation efficiency of *** achieve higher fiber positioning accuracy,the original open-loop controlled fiber positioning system urgently needs to be upgraded into a closed-loop control *** fiber detection is the most important part of the closed-loop controlled fiber positioning *** back-illuminated detection method is usually used to detect the fiber position by directly detecting the light spot generated at the fiber end in the multi-fiber spectral *** this paper,we introduce a new method to measure the fiber position based on the image of the front-illuminated LAMOST focal *** front-illuminated image does not require lighting devices inside the spectrograph,and it could reduce the instability and light pollution in the spectrograph *** method measures the fiber position by fitting the profile of the fiber pinhole with a 2D Gaussian function.A series of tests show that the relative position measurement precision of the front-illuminated method is about 012,and the method could have the same accuracy as the back-illuminated method once the system bias is calibrated by a simple radial correction *** required fiber positioning accuracy of LAMOST is 04,and the new method satisfies the requirement of LAMOST fiber detection accuracy and could be used in the closed-loop fiber control system.

关键词： techniques image processing-methods data analysis-instrumentation detectors

全面抗战时期中国共产党加强科技人才工作的实践

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党的文献 2022年第4期 109-115页

作者：王梦昕中共中央党史和文献研究院北京100017

全面抗战时期,中国共产党着眼于抗日根据地建设和抗战大局的需要,注重加强科技人才工作,对抗日根据地内部主客观条件进行统筹考虑,积极谋划,从科技人才的培养、吸纳、使用、待遇等多方面采取了一系列有力举措。一是培育“既通晓革命理... 详细信息

全面抗战时期,中国共产党着眼于抗日根据地建设和抗战大局的需要,注重加强科技人才工作,对抗日根据地内部主客观条件进行统筹考虑,积极谋划,从科技人才的培养、吸纳、使用、待遇等多方面采取了一系列有力举措。一是培育“既通晓革命理论又懂得自然科学”“理论与实践相统一”的科技人才;二是欢迎科技人才等“专门家来抗日根据地共同进行文化建设与各方面的抗战建国工作”;三是对科技人才“充分的信任”,“给以充分的负责工作”;四是高度重视“技术人员的优待问题”,保障其无后顾之忧。这些举措极大地鼓舞和激发了科技人才的革命热情,有力促进了根据地经济建设事业的进步,为抗日战争的胜利奠定了重要基础,也为新中国成立后科技人才的培养和科技事业的发展提供了经验借鉴。

关键词：全面抗战时期科技人才抗日根据地建设

破片与冲击波联合作用下多孔泡沫铝夹芯复合材料板的防护性能

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兵工学报 2021年第5期42卷 1041-1052页

作者：王孟鑫陈睿颖王金相南京理工大学瞬态物理国家重点实验室江苏南京210094 南京理工大学自动化学院江苏南京210094

多孔泡沫铝钛合金板不仅克服了传统防护结构质量大、运输不便等缺点,还具有耐疲劳、比强度高等优点,对抗爆防护材料轻质化、高效化具有十分重要的意义。采用有限元仿真分析软件LS-DYNA,对夹芯复合材料板在冲击波与破片联合作用下的失效... 详细信息

多孔泡沫铝钛合金板不仅克服了传统防护结构质量大、运输不便等缺点,还具有耐疲劳、比强度高等优点,对抗爆防护材料轻质化、高效化具有十分重要的意义。采用有限元仿真分析软件LS-DYNA,对夹芯复合材料板在冲击波与破片联合作用下的失效模式和防护性能展开了数值模拟,对比分析了不同排列方式下泡沫铝夹芯结构对背板变形程度的影响。结果表明:在40 cm爆距下,破片会先于冲击波对靶板进行作用,且破片载荷强度远大于冲击波载荷强度;当厚度方向的结构按照“1 mm厚钛合金面板+10 mm厚泡沫铝+10 mm厚泡沫铝+10 mm厚纤维+1 mm厚钛合金背板”排列时,背板变形位移最小,结构总内能最高,分别为13.9 mm和52.7 kJ,此工况可以更有效地降低结构整体变形程度,吸收面板变形所产生的能量。

关键词：夹芯复合结构破片与冲击波耦合防护性能毁伤机理数值模拟

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美国R&D资本存量测算及对我国的启示

统计研究 2011年第6期28卷 58-63页

作者：王孟欣河北大学经济学院统计学系

有关R&D资本存量的测算理论与方法问题,国内研究尚处于起步阶段,国外一些学者则进行了较深入的研究。美国BEA通过R&D卫星账户的构建在R&D资本存量测算方面积累了大量经验。本文首先分析了R&D资本存量测算中存在的困难,并基于2007年美国... 详细信息

有关R&D资本存量的测算理论与方法问题,国内研究尚处于起步阶段,国外一些学者则进行了较深入的研究。美国BEA通过R&D卫星账户的构建在R&D资本存量测算方面积累了大量经验。本文首先分析了R&D资本存量测算中存在的困难,并基于2007年美国R&D卫星账户,对BEA关于R&D资本存量的测算方法进行介绍与分析,最后指出了我国R&D资本存量测算需要进一步做的工作。

关键词： R&D R&D资本存量 BEA

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基于樽海鞘群算法的无源时差定位

电子与信息学报 2018年第7期40卷 1591-1597页

作者：陈涛王梦馨黄湘松哈尔滨工程大学信息与通信工程学院哈尔滨150001

针对无源时差(TDOA)定位的非线性方程解算问题,论文使用一种名为樽海鞘群算法(SSA)的新的群体智能优化算法。首先,该算法采用一种新的群体更新模型,充分平衡迭代过程中的探索行为与开发行为,在保证搜索的全局性与个体的多样性的同时,改... 详细信息

针对无源时差(TDOA)定位的非线性方程解算问题,论文使用一种名为樽海鞘群算法(SSA)的新的群体智能优化算法。首先,该算法采用一种新的群体更新模型,充分平衡迭代过程中的探索行为与开发行为,在保证搜索的全局性与个体的多样性的同时,改善了其他智能优化算法容易陷入局部极值的问题。其次,该算法控制参数很少,运算速度明显提高。该算法的收敛速度十分稳定,定位精度更高。仿真结果表明,樽海鞘群算法在3维时差定位中能够快速、稳定地收敛至目标位置,对传统粒子群算法(PSO)、改进的线性权重粒子群算法(IPSO)与SSA的定位精度进行比较,SSA精度明显高于PSO与IPSO。

关键词：无源定位到达时差智能优化算法樽海鞘群算法