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旋髂浅动脉穿支接力皮瓣修复大面积股前外侧皮瓣供区缺损的疗效评价

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中华手外科杂志 2024年第3期40卷 269-272页

作者：陶先耀薛明宇周晓强力王进芮永军无锡市第九人民医院手外科无锡214062

目的探讨以旋髂浅动脉穿支皮瓣为接力皮瓣修复大面积股前外侧皮瓣供区继发性缺损的临床疗效.方法回顾性分析自2020年1月至2022年12月我科采用双侧股前外侧皮瓣瓦合修复手部套脱伤创面8例,并利用旋髂浅动脉穿支皮瓣修复较大面积的股前外... 详细信息

目的探讨以旋髂浅动脉穿支皮瓣为接力皮瓣修复大面积股前外侧皮瓣供区继发性缺损的临床疗效.方法回顾性分析自2020年1月至2022年12月我科采用双侧股前外侧皮瓣瓦合修复手部套脱伤创面8例,并利用旋髂浅动脉穿支皮瓣修复较大面积的股前外侧皮瓣供区创面,对其疗效进行评价.结果术后8例股前外侧皮瓣和旋髂浅动脉穿支皮瓣均存活,伤口I期愈合.术后随访时间为6~12个月,平均7.2个月,术后髂腹股沟区和股前外侧供区创面平整,仅留线性瘢痕,皮肤质地柔软,与相邻皮肤颜色无明显差异.患肢髋、膝关节活动正常,股外侧区无麻木症状.结论选取旋髂浅动脉穿支接力皮瓣修复大面积股前外侧皮瓣供区创面,手术操作简单,皮瓣成活率高且修复效果良好,值得临床推广.

关键词：外科皮瓣治疗结果供区创面旋骼浅动脉穿支

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基于Elasticsearch的挂号系统设计与实现

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中国医学装备 2024年第2期21卷 109-113页

作者：曹勐琪于泓涛梁振安徽医科大学生物医学工程学院合肥230032 爱特美德(安徽)智能科技有限公司合肥230032

目的:设计并实现基于Elasticsearch的挂号系统,解决传统挂号系统预约挂号方式单一和搜索挂号平台信息片面等问题,以满足患者日益增长的多元化和智能化就诊需求。方法:采用浏览器与服务器(B/S)架构实现挂号系统设计,前端使用有机对象描... 详细信息

目的:设计并实现基于Elasticsearch的挂号系统,解决传统挂号系统预约挂号方式单一和搜索挂号平台信息片面等问题,以满足患者日益增长的多元化和智能化就诊需求。方法:采用浏览器与服务器(B/S)架构实现挂号系统设计,前端使用有机对象描述语言(NOODL)渲染界面,并通过Typescript实现函数方法和接口数据交互,Elasticsearch搜索引擎实现高效的搜索功能。后端通过基于边的云对象存储(ECOS)系统处理数据请求,并将业务数据存储在MySQL数据库中。系统包括应用层、服务层和存储层3层架构,可实现登录注册、搜索预约、链接预约、扫码预约、医生设置预约信息等功能。结果:基于Elasticsearch的挂号系统可实现线上搜索预约、医院专属链接预约、扫码预约等多种预约挂号方式,适用于Web和移动设备等多个平台。截止2023年6月,系统拥有医生219人,服务19903例患者,完成预约62737次,为患者就医节省大量时间,提高了医院运转效率。结论:基于Elasticsearch的挂号系统能够满足患者的多元化和智能化就诊需求,为患者提供全面、准确及智能的预约诊疗服务,有效提高诊疗效率。

关键词： Elasticsearch搜索引擎有机对象描述语言(NOODL) 搜索预约多元化预约方式综合性挂号平台

基于旅游相关利益主体需求的传统村落空间价值评价研究

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城市建筑 2024年第7期21卷 61-66页

作者：曹梦琪张定青卢泰儒西安交通大学人居环境与建筑工程学院

传统村落近年来成为乡村旅游发展的热点,旅游开发过程中对政府、企业、村民、游客等相关主体的利益冲突处理不当,可能造成空间资源滥用、原有历史文化价值丧失等问题。基于乡村旅游视角梳理了与乡村旅游活动相关的传统村落空间构成子系... 详细信息

传统村落近年来成为乡村旅游发展的热点,旅游开发过程中对政府、企业、村民、游客等相关主体的利益冲突处理不当,可能造成空间资源滥用、原有历史文化价值丧失等问题。基于乡村旅游视角梳理了与乡村旅游活动相关的传统村落空间构成子系统及其旅游资源要素,通过乡村旅游各相关利益主体空间需求及其矛盾分析,提取归纳体现各类主体主导性需求的传统村落空间价值构成;运用层次分析法,结合文献研究、调研访谈、德尔菲法等方法构建乡村旅游视角下的传统村落空间价值评价体系,并依据评价结果探讨传统村落旅游适宜的开发模式、开发类型和空间主要利用方式,有助于在空间规划操作层面协调各主体之间的矛盾,为村落空间合理开发提供分析思路和方法借鉴。

关键词：乡村旅游传统村落价值评价相关利益主体

MDIVis: Visual analytics of multiple destination images on tourism user generated content

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Visual Informatics 2022年第3期6卷 1-10页

作者： Changlin Li mengqi cao Xiaolin Wen Haotian Zhu Shangsong Liu Xinyi Zhang Min Zhu College of Computer Science Sichuan UniversityChengdu 610065China Department of Computing Xi’anJiaotong-Liverpool UniversitySuzhou 215000China

Abundant tourism user-generated content(UGC)contains a wealth of cognitive and emotional in-formation,providing valuable data for building destination images that depict tourists’experiences and appraisal of the destinations during the *** particular,multiple destination images can assist tourism managers in exploring the commonalities and differences to investigate the elements of interest of tourists and improve the competitiveness of the ***,existing methods usually focus on the image of a single destination,and they are not adequate to analyze and visualize UGC to extract valuable information and ***,we discuss requirements with tourism experts and present MDIVis,a multi-level interactive visual analytics system that allows analysts to comprehend and analyze the cognitive themes and emotional experiences of multiple destination images for ***,we design a novel sentiment matrix view to summarize multiple destination images and improve two classic views to analyze the time-series pattern and compare the detailed information of ***,we demonstrate the utility of MDIVis through three case studies with domain experts on real-world data,and the usability and effectiveness are confirmed through expert interviews.

关键词： Tourism destination images Visual analysis Sentiment visualization User-generated content

Aspect-Level Sentiment Analysis Based on Deep Learning

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Computers, Materials & Continua 2024年第3期78卷 3743-3762页

作者： mengqi Zhang Jiazhao Chai Jianxiang cao Jialing Ji Tong Yi Department of Communication University of New South WalesSydney2052Australia Higher Vocational Education Publishing Division Higher Education PressBeijing100029China State Key Laboratory of Media Convergence and Communication Communication University of ChinaBeijing100020China Key Lab of Education Blockchain and Intelligent Technology Ministry of EducationGuangxi Normal UniversityGuilin541004China

In recent years,deep learning methods have developed rapidly and found application in many fields,including natural language *** the field of aspect-level sentiment analysis,deep learning methods can also greatly improve the performance of ***,previous studies did not take into account the relationship between user feature extraction and contextual *** address this issue,we use data feature extraction and deep learning combined to develop an aspect-level sentiment analysis *** be specific,we design user comment feature extraction(UCFE)to distill salient features from users’historical comments and transform them into representative user feature ***,the aspect-sentence graph convolutional neural network(ASGCN)is used to incorporate innovative techniques for calculating adjacency matrices;meanwhile,ASGCN emphasizes capturing nuanced semantics within relationships among aspect words and syntactic dependency ***,three embedding methods are devised to embed the user feature vector into the ASGCN *** empirical validations verify the effectiveness of these models,consistently surpassing conventional benchmarks and reaffirming the indispensable role of deep learning in advancing sentiment analysis methodologies.

关键词： Aspect-level sentiment analysis deep learning graph convolutional neural network user features syntactic dependency tree

Canopy structure:An intermediate factor regulating grassland diversity-function relationships under human disturbances

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Fundamental Research 2023年第2期3卷 179-187页

作者： Xiaoxia Zhao Yuhao Feng Kexin Xu mengqi cao Shuya Hu Qiuli Yang Xiaoqiang Liu Qin Ma Tianyu Hu Maggi Kelly Qinghua Guo Yanjun Su State Key Laboratory of Vegetation and Environmental Change Institute of BotanyChinese Academy of SciencesBeijing 100093China University of Chinese Academy of Sciences Beijing 100049China Institute of Ecology College of Urban and Environmental SciencePeking UniversityBeijing 100871China Patent Examination Cooperation Sichuan Center of the Patent Office China National Intellectual Property AdministrationChengduSichuan 610213China Department of Environmental Sciences Policy and ManagementUniversity of CaliforniaBerkeleyCA 94720United States Division of Agriculture and Natural Resources University of CaliforniaBerkeleyCA 94720United States Institute of Remote Sensing and Geographical Information Systems School of Earth and Space SciencesPeking UniversityBeijing 100871China

Grasslands are one of the largest coupled human-nature terrestrial ecosystems on Earth,and severe anthropogenic-induced grassland ecosystem function declines have been reported *** factors influencing grassland ecosystem functions is critical for making sustainable management *** structure is an important factor influencing plant growth through mediating within-canopy microclimate(e.g.,light,water,and wind),and it is found coordinating tightly with plant species diversity to influence forest ecosystem ***,the role of canopy structure in regulating grassland ecosystem functions along with plant species diversity has been rarely ***,we investigated this problem by collecting field data from 170 field plots distributed along an over 2000 km transect across the northern agro-pastoral ecotone of *** net primary productivity(ANPP)and resilience,two indicators of grassland ecosystem functions,were measured from field data and satellite remote sensing *** laser scanning data were collected to measure canopy structure(represented by mean height and canopy cover).Our results showed that plant species diversity was positively correlated to canopy structural traits,and negatively correlated to human activity *** structure was a significant indicator for ANPP and resilience,but their correlations were inconsistent under different human activity intensity *** to plant species diversity,canopy structural traits were better indicators for grassland ecosystem functions,especially for *** structure equation modeling analyses,we found that plant species diversity did not have a direct influence on ANPP under human ***,it had a strong indirect effect on ANPP by altering canopy structural *** to resilience,plant species diversity had both a direct positive contribution and an indirect contribution through mediating canopy *** study highlig

关键词： Grassland ecosystem function Canopy structure Plant species diversity Human activity intensity Northern agro-pastoral ecotone

GM-CSF Promotes the Development of Dysfunctional Vascular Networks in Moyamoya Disease

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Neuroscience Bulletin 2024年第4期40卷 451-465页

作者： Huiqin Li Xiang cao Xinya Gu mengqi Dong Lili Huang Chenglu Mao Shengnan Xia Haiyan Yang Xinyu Bao Yongbo Yang Yun Xu Department of Neurology and Neurosurgery Nanjing Drum Tower HospitalAffiliated Hospital of Medical SchoolNanjing UniversityNanjing210008China Department of Neurology and Neurosurgery Nanjing Drum Tower HospitalState Key Laboratory of Pharmaceutical Biotechnology and Institute of Translational Medicine for Brain Critical DiseasesNanjing UniversityNanjing210008China Department of Neurology and Neurosurgery Nanjing Drum Tower Hospital Clinical College of Xuzhou Medical UniversityNanjing210008China Department of Neurology and Neurosurgery Nanjing Drum Tower Hospital Clinical College of Nanjing Medical UniversityNanjing210008China Jiangsu Key Laboratory for Molecular Medicine Medical School of Nanjing UniversityNanjing210008China Jiangsu Provincial Key Discipline of Neurology Nanjing210008China Nanjing Neurology Medical Center Nanjing210008China

Moyamoya disease(MMD)is a chronic occlusive cerebrovascular disease with the development of a network of abnormal *** inflammation is associated with the occurrence and development of ***,the mechanisms underlying the formation of the abnormal vascular network remain ***-eight patients with MMD,26 ischemic stroke patients,and 26 unrelated healthy volunteers were enrolled in this study The data showed that the levels of granulocyte-macrophage colony-stimulating factor(GM-CSF)were higher in MMD patients than in healthy controls(P<0.01),and GM-CSF was mainly from Th1 and Th17 cells in *** found that increased GM-CSF drove monocytes to secrete a series of cytokines associated with angiogenesis,inflammation,and *** summary,our findings demonstrate for the first time the important involvement of GM-CSF in MMD and that GM-CSF is an important factor in the formation of abnormal vascular networks in MMD.

关键词： Moyamoya disease Vascular endothelial cells GM-CSF VEGF

数字减影血管造影足部血管交叉征象在判断跖背动脉分型中的初步应用

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骨科临床与研究杂志 2024年第2期9卷 86-90页

作者：谭哲伦杨勇李金勇李斌李峰王志新王扬徐小龙黄行健曹梦琦首都医科大学附属北京积水潭医院创伤骨科 100035 首都医科大学附属北京积水潭医院手外科 100035 首都医科大学附属北京积水潭医院血管外科 100035

目的探究数字减影血管造影(DSA)中一种足部血管交叉征象在判断第一跖背动脉分型中的可行性。方法选取2021年10月~2023年3月在首都医科大学附属北京积水潭医院手外科治疗的11例住院患者,均单侧拇指缺如,并在趾甲皮瓣术式修复拇指的术... 详细信息

目的探究数字减影血管造影(DSA)中一种足部血管交叉征象在判断第一跖背动脉分型中的可行性。方法选取2021年10月~2023年3月在首都医科大学附属北京积水潭医院手外科治疗的11例住院患者,均单侧拇指缺如,并在趾甲皮瓣术式修复拇指的术前进行了供区足部数字减影血管造影检查,根据造影结果对第一跖背动脉的Gilbert分型进行判断,并在术中进行验证。结果入组的11例患者中,根据DSA结果的后前位和侧位判断第一跖背动脉分型,其中GilbertⅠ型3例(27.3%),Ⅱa型4例(36.4%),Ⅱb型1例(9.1%),Ⅲ型共3例(27.3%)。GilbertⅠ型和Ⅱ型的足背和第一跖背动脉与足底动脉和足底外侧动脉均在DSA时显影构成血管交叉征象。术中显露跖背动脉后所见血管情况与术前通过数字减影血管造影判断的Gilbert分型完全吻合,准确率为100%。本组患者术后趾甲皮瓣全部成活。结论第一跖背动脉在血管造影显示的血管交叉征象是明确判断其Gilbert分型的重要征象,对于切取长血管蒂趾甲皮瓣术前规划具有重要意义。

关键词：血管造影术穿支皮瓣跖背动脉 Gilbert分型血管交叉征象

Development of a single transcript CRISPR/Cas9 toolkit for efficient genome editing in autotetraploid alfalfa

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The Crop Journal 2024年第3期12卷 788-795页

作者： Haixia Zhao Siyi Zhao Yingping cao Xiping Jiang Lijuan Zhao Zhimeng Li mengqi Wang Ruijuan Yang Chuanen Zhou Zhaoming Wang Feng Yuan Dongmei Ma Hao Lin Wenwen Liu Chunxiang Fu CAS Key Laboratory of Biofuels Shandong Provincial Key Laboratory of Energy GeneticsQingdao Institute of Bioenergy and Bioprocess TechnologyChinese Academy of SciencesQingdao 266101ShandongChina Shandong Energy Institute Qingdao 266101ShandongChina Qingdao New Energy Shandong Laboratory Qingdao 266101ShandongChina University of Chinese Academy of Sciences Beijing 100049China The Key Laboratory of Plant Development and Environmental Adaptation Biology Ministry of EducationSchool of Life SciencesShandong UniversityQingdao 266101ShandongChina Key Laboratory of Forage Breeding and Seed Production of Inner Mongolia Inner Mongolia M-Grass Ecology and Environment(Group)Co.Ltd.Hohhot 010016Inner MongoliaChina School of Ecology Environment Ningxia UniversityYinchuan 750021NingxiaChina Biotechnology Research Institute Chinese Academy of Agricultural SciencesBeijing 100081China

Alfalfa(Medicago sativa.L.)is a globally significant autotetraploid legume forage ***,despite its importance,establishing efficient gene editing systems for cultivated alfalfa remains a formidable *** this study,we pioneered the development of a highly effective ultrasonic-assisted leaf disc transformation system for Gongnong 1 alfalfa,a variety widely cultivated in Northeast ***,we created a single transcript CRISPR/Cas9(CRISPR_2.0)toolkit,incorporating multiplex gRNAs,designed for gene editing in Gongnong *** Cas9 and gRNA scaffolds were under the control of the Arabidopsis ubiquitin-10 promoter,a widely employed polymeraseⅡconstitutive promoter known for strong transgene expression in *** assess the toolkit’s efficiency,we targeted PALM1,a gene associated with a recognizable multifoliate *** the CRISPR_2.0 toolkit,we directed PALM1 editing at two sites in the wild-type Gongnong *** indicated a 35.1%occurrence of editing events all in target 2 alleles,while no mutations were detected at target 1 in the transgenic-positive *** explore more efficient sgRNAs,we developed a rapid,reliable screening system based on Agrobacterium rhizogenes-mediated hairy root transformation,incorporating the visible reporter *** screening system demonstrated that most purple visible hairy roots underwent gene ***,sgRNA3,with an 83.0%editing efficiency,was selected using the visible hairy root *** anticipated,tetra-allelic homozygous palm1 mutations exhibited a clear multifoliate *** palm1 lines demonstrated an average crude protein yield increase of 21.5%compared to trifoliolate *** findings highlight the modified CRISPR_2.0 system as a highly efficient and robust gene editing tool for autotetraploid alfalfa.

关键词： Alfalfa Gene editing CRISPR_2.0 toolkit Hairy root system Tetra-allelic homozygous mutants