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The traumatic narratives of sexuality in Chinese writer Shao-Lin Chu’s trilogy

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Language and Semiotic Studies 2024年第1期10卷 106-131页

作者： Hsiu-Chih tsai Department of Foreign Languages and Literatures National Taiwan UniversityTaipeiTaiwan

This paper explores the narratives of the Chinese woman novelist Shao-Lin Chu’s trilogy to see how the problem of female sexuality and resistance to parental wedlock tragedy becomes a traumatic *** traumatic symptoms in the narratives are taken as Peircean signs for tracing the negative influences of traumatic experiences on the formation of personal identity and the associated depressive *** scenes portrayed in Chu’s traumatic narratives of female and male sexuality are implications and representations of how sexuality is conceptualized and confined by the traumatic events while backgrounded with regulations and restrictions of a traditional *** stories of Chu’s female narrators reveal the persistent and resisting feminine *** paper adopts the concept of feminist narrative to analyze the traumatic and sexual events in Chu’s *** decoding and re-encoding of resistance and sexuality in the traumatic narratives prove that the narratological textual analysis and semiotic reading strategy together offer a solid approach to the discovery of the persistent traumatic impacts of the secret veiled in the narratives and reveal the probable strength of compassion that has its roots derived from deplorable trauma but later transforms itself to stimulate a positive reconstruction of the traumatic survivors’identity.

关键词： traumatic narrative sexuality resistance textual analysis Peirce’s semiosis Shao-Lin Chu

Erlotinib combination with a mitochondria-targeted ubiquinone effectively suppresses pancreatic cancer cell survival

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World Journal of Gastroenterology 2024年第7期30卷 714-726页

作者： Pui-Yin Leung Wenjing Chen Anissa N Sari Poojitha Sitaram Pui-Kei Wu Susan tsai Jong-In Park Department of Biochemistry Medical College of WisconsinMilwaukeeWI 53226United States Department of Surgery Medical College of WisconsinMilwaukeeWI 53226United States

BACKGROUND Pancreatic cancer is a leading cause of cancer-related *** activity of the epidermal growth factor receptor(EGFR)is often observed in pancreatic cancer,and the small molecule EGFR inhibitor erlotinib has been approved for pancreatic cancer therapy by the food and drug ***,erlotinib alone is ineffective and should be combined with other drugs to improve therapeutic *** previously showed that certain receptor tyrosine kinase inhibitors can increase mitochondrial membrane potential(Δψm),facilitate tumor cell uptake ofΔψm-sensitive agents,disrupt mitochondrial homeostasis,and subsequently trigger tumor cell *** has not been tested for this *** To determine whether erlotinib can elevateΔψm and increase tumor cell uptake ofΔψm-sensitive agents,subsequently triggering tumor cell ***Δψm-sensitive fluorescent dye was used to determine how erlotinib affectsΔψm in pancreatic adenocarcinoma(PDAC)cell *** viability of conventional and patient-derived primary PDAC cell lines in 2D-and 3D cultures was measured after treating cells sequentially with erlotinib and mitochondria-targeted ubiquinone(MitoQ),aΔψm-sensitive *** synergy between erlotinib and MitoQ was then analyzed using SynergyFinder *** preclinical efficacy of the twodrug combination was determined using immune-compromised nude mice bearing PDAC cell line *** Erlotinib elevatedΔψm in PDAC cells,facilitating tumor cell uptake and mitochondrial enrichment ofΔψm-sensitive *** triggered caspase-dependent apoptosis in PDAC cells in culture if used at high doses,while erlotinib pretreatment potentiated low doses of *** suggested that these drugs synergistically induced tumor cell *** with in vitro data,erlotinib and MitoQ combination suppressed human PDAC cell line xenografts in mice more effectively than single treatments of each *** Our findings suggest tha

关键词： Pancreatic cancer Erlotinib Mitochondria-targeted ubiquinone Mitochondria Combination therapy

Long-term Integration Ability of the Submillimeter Wave Astronomy Satellite(SWAS)Spectral Line Receivers

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Research in Astronomy and Astrophysics 2024年第6期24卷 315-322页

作者： Bing-Ru Wang Di Li Paul F.Goldsmith Jingwen Wu Chao-Wei tsai Rudolf Schieder Gary J.Melnick National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China University of Chinese Academy of Sciences Beijing 100049China Research Center for Astronomical Computing Zhejiang LaboratoryHangzhou 311100China Jet Propulsion Laboratory California Institute of TechnologyPasadenaCA 91109USA Institute for Frontiers in Astronomy and Astrophysics Beijing Normal UniversityBeijing 102206China KOSMA I.Physik.InstitutUniversität zu KölnZülpicher Str.7750937 KölnGermany Center for Astrophysics|Harvard&Smithsonian 60 Garden StreetMS 66CambridgeMA 02138USA

The Submillimeter Wave Astronomy Satellite(SWAS)was the first space telescope capable of high spectral resolution observations of terahertz spectral *** have investigated the integration ability of its two receivers and spectrometer during five and a half years of on-orbit *** CI,O_(2),H_(2)O,and^(13)CO spectra taken toward all observed Galactic sources were *** present results are based on spectra with a total integration time of up to 2.72×10~4hr(■10~8s).The noise in the spectra is generally consistent with that expected from the radiometer equation,without any sign of approaching a noise *** noise performance reflects the extremely stable performance of the passively cooled front end as well as other relevant components in the SWAS instrument throughout its mission lifetime.

关键词： telescopes space vehicles:instruments instrumentation:miscellaneous ISM:lines and bands

Dynamic control of district heating networks with integrated emission modelling:A dynamic knowledge graph approach

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Energy and AI 2024年第3期17卷 29-47页

作者： Markus Hofmeister Kok Foong Lee Yi-Kai tsai Magnus Müller Karthik Nagarajan Sebastian Mosbach Jethro Akroyd Markus Kraft Department of Chemical Engineering and Biotechnology University of CambridgePhilippa Fawcett DriveCambridgeCB30ASUnited Kingdom Cambridge Centre for Advanced Research and Education in Singapore CARES Ltd.1 Create WayCREATE Tower#05-05138602Singapore CMCL Innovations Sheraton HouseCambridgeCB30AXUnited Kingdom The Alan Turing Institute 96 Euston RoadLondonNW12DBUnited Kingdom

This paper presents a knowledge graph-based approach for the dynamic control of a district heating network with integrated emission dispersion modelling. We propose an interoperable and extensible implementation to forecast the anticipated heat demand of a municipal heating network, minimise associated total generation cost based on a previously devised methodology, and couple it with dispersion simulations for induced airborne pollutants to provide automatic insights into air quality implications of various heat sourcing strategies. We create cross-domain interoperability in the nexus of energy and air quality via newly developed ontologies and semantic software agents, which can be chained together via The World Avatar dynamic knowledge graph to resemble the behaviour of complex systems. Furthermore, we integrate the City Energy Analyst into this ecosystem to provide building-level insights into energy demand and renewable generation potential to foster strategic analyses and scenario planning. Underlying calculations use building and weather data from the knowledge graph in place of inherent assumptions in the official software release, facilitating a more data-driven approach. All use cases are implemented for a mid-size town in Germany as a proof-of-concept, and a unified visualisation interface is provided, allowing for the examination of 3D buildings alongside their corresponding energy demand and supply time series, as well as emission dispersion data. With this work, we outline the potential of Semantic Web technologies to connect digital twins for holistic energy modelling in smart cities, thereby addressing the increasing complexity of interconnected energy systems.

关键词： Knowledge graph Digital twin Inter operability Energy modelling Emi ssion dispersi on

Optical Extinctions of Inter-Arm Molecular Clouds in M31:A Pilot Study for the Upcoming CSST Observations

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Research in Astronomy and Astrophysics 2024年第6期24卷 323-333页

作者： Cailing Chen Zheng Zheng Chao-Wei tsai Sihan Jiao Jing Tang Jingwen Wu Di Li Yun Zheng Linjing Feng Yujiao Yang Yuan Liang National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China University of Chinese Academy of Sciences Beijing 100049China Key Laboratory of Radio Astronomy and Technology Chinese Academy of SciencesBeijing 100101China Institute for Frontiers in Astronomy and Astrophysics Beijing Normal UniversityBeijing 102206China Zhejiang Lab Hangzhou 311121China

Recent submillimeter dust thermal emission observations have unveiled a significant number of inter-arm massive molecular clouds in ***,the effectiveness of this technique is limited to its sensitivity,making it challenging to study more distant *** study introduces an alternative approach,utilizing optical extinctions derived from space-based telescopes,with a focus on the forthcoming China Space Station Telescope(CSST).We first demonstrate the capability of this method by constructing dust extinction maps for 17 inter-arm massive molecular clouds in M31 using the Panchromatic Hubble Andromeda Treasury *** analysis reveals that inter-arm massive molecular clouds with an optical extinction(A_(V)) greater than 1.6 mag exhibit a notable A_(V) excess,facilitating their *** majority of these inter-arm massive molecular clouds show an A_(V) around 1 mag,aligning with measurements from our JCMT *** validation using a mock CSST RGB star catalog confirms the method's *** show that the derived A_(V)values using CSST z and y photometries align more closely with the input *** clouds with A_(V)> 1.6 mag can also be identified using the CSST mock *** thus claim that future CSST observation clouds provide an effective way for the detection of inter-arm massive molecular clouds with significant optical extinction in nearby galaxies.

关键词： infrared:stars ISM:clouds Galaxy:structure

Exploring the Relationship Between Patent Forward Citation and Stock Return Rate Using Empirical Data of China Stock Market

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Management Studies 2024年第2期12卷 67-83页

作者： Hong-Wen tsai Hui-Chung Che National Taiwan University of Science and Technology TaipeiTaiwanChina China Bio-Medical&Technology Applications Associate New TaipeiTaiwanChina

A novel indicator called price-citation was *** on the company integrated patent database of China listed companies of common stocks(A-shares)with the stock price and the stock return rate data,more than two thousand of A-shares from 2017 to 2020 were *** effect of the traditional patent forward citation and the price-citation for discriminating the stock return rate was thoroughly analyzed via *** A-shares of forward citation counts above the average showed higher stock return rate means than the A-shares having patents but receiving no forward *** price-citation,combining both the financial and patent attributes,defined as the multiplication of the current stock price and the currently receiving forward citation count,showed its excellence in discriminating the stock return *** A-shares of higher price-citation showed significantly higher stock return rate means while the A-shares of lower price-citation showed significantly lowest stock return rate *** price-citation effect had not been changed by COVID-19 though COVID-19 affected the social and economic environment to a considerable extent in 2020.

关键词： China A-share patent ANOVA stock return rate forward citation price-citation

Special issue on meta-lenses

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Opto-Electronic Science 2024年第9期3卷 1-2页

作者： Din Ping tsai Shumin Xiao Department of Electrical Engineering City University of Hong KongKowloonHong Kong SAR 999077China Centre for Biosystems Neuroscienceand NanotechnologyCity University of Hong KongKowloonHong Kong SAR 999077China The State Key Laboratory of Terahertz and Millimeter Waves City University of Hong KongKowloonHong Kong SAR 999077China State Key Laboratory on Tunable Laser Technology Ministry of Industry and Information Technology Key Lab of Micro-Nano Optoelectronic Information SystemShenzhen Graduate SchoolHarbin Institute of TechnologyShenzhen 518055China

About a decade ago,the unveiling of generalized Snell’s laws heralded a significant advancement in nanophotonics,leading to the emergence of metasurfaces1−*** revolutionary milestone has set the stage for the development of advanced optical devices,particularly metalens7−*** are already well-versed in the fundamental principles and functions of meta-lenses,which exemplify the concept of phase discontinuities with ***,the exploration of meta-lenses is far from over.

关键词： principles phase surfaces

Review of flexible microelectromechanical system sensors and devices

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Nanotechnology and Precision Engineering 2021年第2期4卷 33-53页

作者： Xiaopeng Yang menglun Zhang State Key Laboratory of Precision Measuring Technology and Instruments Tianjin UniversityTianjin 300072China

Today,the vast majority of microelectromechanical system(MEMS)sensors are mechanically rigid and therefore suffer from disadvantages when used in intimately wearable or bio-integrated *** applying new engineering strategies,mechanically bendable and stretchable MEMS devices have been successfully *** article reviews recent progress in this area,focusing on high-performance flexible devices based on inorganic thin *** start with the common design and fabrication strategies for flexibility and stretchability,summarize the recent application-oriented flexible devices,and conclude with criteria and opportunities for the future development of flexible MEMS sensors.

关键词： MEMS sensor Flexible electronics Stretchable sensor

Highly sensitive and stretchable piezoelectric strain sensor enabled wearable devices for real-time monitoring of respiratory and heartbeat simultaneously

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Nanotechnology and Precision Engineering 2022年第1期5卷 12-23页

作者： Zhenjie Ji menglun Zhang State Key Laboratory of Precision Measuring Technology and Instruments Tianjin UniversityTianjin 300072China

The World Health Organization has declared COVID-19 a *** demand for devices or systems to diagnose and track COVID-19 infections noninvasively not only in hospitals but also in home settings has led to increased interest in consumer-grade wearables.A common symptom of COVID-19 is dyspnea,which may manifest as an increase in respiratory and heart *** this paper,a novel piezoelectric strain sensor is presented for real-time monitoring of respiratory and heartbeat signals.A highly sensitive and stretchable piezoelectric strain sensor is fabricated using a piezoelectric film with a serpentine *** thickness of the patterned PVDF flexible piezoelectric strain sensor is only 168μm,and the voltage sensitivity reaches 0.97 mV/με.The effective modulus is 13.5 MPa,which allows the device to fit to the skin and detect the small strain exhibited by the human *** vibrations are captured by the piezoelectric sensor,which produces an electrical output voltage signal conformally mapped with respiratory–cardiac *** separate heart activity and respiratory signals are extracted from the mixed respiratory–cardiac signal by an empirical mode decomposition data processing *** detecting vital signals such as respiratory and heart rates,the proposed device can aid early diagnosis and monitoring of respiratory diseases such as COVID-19.

关键词： Physiological signal Strain sensor High sensitivity Flexibility Early diagnosis COVID-19