检索结果-南通市图书馆

China CDC weekly 2024年第3期6卷 45-50页

作者： Hui Liu Qiyu Zhu Lei Zhang Yujing Liu Peng Xu mengjie Han National Center for AIDS/STD Control and Prevention Chinese Center for Disease Control and PreventionBeijingChina Chinese Association of STD and AIDS Prevention and Control BeijingChina Beijing Chaoyang Kangzhong Health and Education Center BeijingChina

What is already known about this topic?Approximately 80%of newly diagnosed human immunodeficiency virus(HIV)cases among individuals aged 15–24 years in China are attributed to out-ofschool *** is added by this report?This study presents findings on HIV prevalence and comprehensive insights into HIV service utilization,risky behaviors,and prevention knowledge among young out-of-school men who have sex with men(MSM)aged 16–24 years in *** population exhibits a disproportionately high burden of HIV,with only 51.6%of HIV cases previously *** are the implications for public health practice?HIV services should be expanded to include these key *** interventions are needed to remove barriers to regular HIV services faced by young key populations.

关键词： prevention remove expanded

Increased Incidence of Severe Adverse Events in Non-Small Cell Lung Cancer Patients with Previous Tuberculosis Episode Treated with PD-1 Inhibitors

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Biomedical and Environmental Sciences 2024年第7期37卷 785-789页

作者： Hui Zhang Jinfeng Yuan Yuanyuan Xu mengjie Yang Jialin Lyu Xinjie Yang Shuyan Sheng Zhe Qian Qunhui wang Yu Pang Ying Hu Department of Medical Oncology Beijing Chest HospitalCapital Medical University&Beijing Tuberculosis and Thoracic Tumor Research InstituteBeijing 101149China Department of Bacteriology and Immunology Beijing Key Laboratory on Drug-Resistant Tuberculosis ResearchBeijing Chest HospitalCapital Medical University/Beijing Tuberculosis&Thoracic Tumor Research InstituteBeijing 101149China Chinese Center for Disease Control and Prevention Beijing 102206China

Lung cancer is the top cause of cancer deaths *** in immune checkpoint inhibitors(ICIs)have transformed cancer treatment,but their use in lung cancer has led to more side *** study examined if past pulmonary tuberculosis(TB)affects ICIs’effectiveness and safety in lung cancer *** reviewed lung cancer patients treated with ICIs at Beijing Chest Hospital from January 2019 to August 2022.

关键词： Lung lung Cancer

在线全文

学校读者我要写书评

暂无评论

射流角度对平板横向射流的影响

北京航空航天大学学报 2013年第9期39卷 1254-1258页

作者：吴盟额日其太王猛杰杜江毅北京航空航天大学能源与动力工程学院北京100191

采用数值和试验方法研究了射流角度对平板横向射流流动结构和工作特性的影响,将得出的规律应用于射流控制矢量喷管上.在小型风洞试验台上进行试验,用纹影方法来观察实验模型的流场结构,通过静压测点来测量实验模型的壁面压力.研究结果表... 详细信息

采用数值和试验方法研究了射流角度对平板横向射流流动结构和工作特性的影响,将得出的规律应用于射流控制矢量喷管上.在小型风洞试验台上进行试验,用纹影方法来观察实验模型的流场结构,通过静压测点来测量实验模型的壁面压力.研究结果表明:数值与试验结果吻合较好;对平板横向射流,增大射流角度能增大射流上游的分离区,弓形激波位置更靠前,角度增加到一定大小,流场结构变化不再明显;对射流控制矢量喷管进行数值模拟得出,增大射流角度能有效提高喷管的推力矢量性能,在NPR为4.6,SPR为0.7条件下,射流角度从90°增加到130°,推力矢量性能提高28.3%.

关键词：横向射流流体控制推力矢量射流角度纹影

在线全文

学校读者我要写书评

暂无评论

大功率激光作用下光学系统轴向焦移仿真

激光与光电子学进展 2021年第11期58卷 314-320页

作者：丁伟王菲王孟洁翁宁直长春理工大学光电工程学院吉林长春130022

在大功率的光学切割系统中,激光经过光学系统聚焦会产生热量,造成光学系统元件发生热形变和折射率的改变,从而导致镜片焦距发生改变,影响加工效果。利用COMSOL软件对光学系统进行多物理场模型建模,仿真得到连续激光和准连续激光作用下... 详细信息

在大功率的光学切割系统中,激光经过光学系统聚焦会产生热量,造成光学系统元件发生热形变和折射率的改变,从而导致镜片焦距发生改变,影响加工效果。利用COMSOL软件对光学系统进行多物理场模型建模,仿真得到连续激光和准连续激光作用下的镜面形变量和折射率改变情况,将镜片受热后数据导入ZEMAX中进行光束追迹,仿真计算出光学系统焦点的轴向偏移量。功率越大,焦点偏移量越大;脉宽越大,焦点偏移量越小;重复频率越高,焦点偏离量越小。最后通过引入对流系数对焦点偏移进行补偿,同时改变对流系数可以控制焦点的位置。该研究解决了大功率激光加工过程中的轴向焦点偏移量测量难的问题,为大功率激光切割设备的焦点控制提供理论依据。

关键词：激光光学大功率激光焦点位移 COMSOL 光束追迹焦移补偿

Growth hormone promotes the reconstruction of injured axons in the hypothalamo-neurohypophyseal system

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2024年第10期19卷 2249-2258页

作者： Kai Li Zhanpeng Feng Zhiwei Xiong Jun Pan Mingfeng Zhou Weizhao Li Yichao Ou Guangsen Wu mengjie Che Haodong Gong Junjie Peng Xingqin wang Songtao Qi Junxiang Peng Department of Neurosurgery Institute of Brain DiseasesNanfang HospitalSouthern Medical UniversityGuangzhouGuangdong ProvinceChina

Previous studies have shown that growth hormone can regulate hypothalamic energy metabolism, stress, and hormone release. Therefore, growth hormone has great potential for treating hypothalamic injury. In this study, we established a specific hypothalamic axon injury model by inducing hypothalamic pituitary stalk electric lesions in male mice. We then treated mice by intraperitoneal administration of growth hormone. Our results showed that growth hormone increased the expression of insulin-like growth factor 1 and its receptors, and promoted the survival of hypothalamic neurons, axonal regeneration, and vascular reconstruction from the median eminence through the posterior pituitary. Altogether, this alleviated hypothalamic injury-caused central diabetes insipidus and anxiety. These results suggest that growth hormone can promote axonal reconstruction after hypothalamic injury by regulating the growth hormone-insulin-like growth factor 1 axis.

关键词： arginine vasopressin growth hormone hypothalamo-neurohypophyseal system hypothalamus injury insulin-like growth factor 1 oxytocin regeneration

Energy Plant—Sweet Sorghum and Ethanol Production Technology Using Sweet Sorghum Stalk

在线全文

学校读者我要写书评

暂无评论

Energy Plant—Sweet Sorghum and Ethanol Production Technolog...

自体脂肪移植在上睑凹陷矫正中的临床应用进展

作者： wang mengjie Sun Hong Xiao Mingsong Chinese Academy of Agricultural Engineering,Beijing 100026

Finding perpetual substitution for fossil energy focuses on nowadays the emerging problem of global energy recourse *** sweet sorghum-energy crop as an example, this paper introduced sweet sorghum and ethanol producti... 详细信息

关键词： energy resource sweet sorghum ethanol

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

中华整形外科杂志 2023年第11期39卷 1272-1276页

作者：王孟洁杨晓楠中国医学科学院北京协和医学院整形外科医院血管瘤与脉管畸形科北京100144

上睑凹陷是指上睑区眶下缘处凹陷,对眼部美观有较大影响,是面部年轻化领域的重要课题。该文对近年来不同类型脂肪组织在上睑凹陷矫正中的临床应用及研究进展进行系统介绍,旨在为寻找更高效、合理的上睑凹陷矫正方式提供理论依据和科学... 详细信息

上睑凹陷是指上睑区眶下缘处凹陷,对眼部美观有较大影响,是面部年轻化领域的重要课题。该文对近年来不同类型脂肪组织在上睑凹陷矫正中的临床应用及研究进展进行系统介绍,旨在为寻找更高效、合理的上睑凹陷矫正方式提供理论依据和科学指导。

关键词：眼睑上睑凹陷修复外科手术脂肪移植自体脂肪

Repressing iron overload ameliorates central poststroke pain via the Hdac2-Kv1.2 axis in a rat model of hemorrhagic stroke

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2024年第12期19卷 2708-2722页

作者： He Fang mengjie Li Jingchen Yang Shunping Ma Li Zhang Hongqi Yang Qiongyan Tang Jing Cao Weimin Yang Department of Neurology The First Affiliated Hospital of Zhengzhou UniversityZhengzhouHenan ProvinceChina Department of Molecular Neuropathology Beijing Neurosurgical InstituteCapital Medical UniversityBeijingChina Department of Nutrition The First Affiliated Hospital of Zhengzhou UniversityZhengzhouHenan ProvinceChina Department of Neurology Henan Provincial People’s HospitalZhengzhouHenan ProvinceChina Department of Human Anatomy School of Basic Medical SciencesZhengzhou UniversityZhengzhouHenan ProvinceChina Neuroscience Research Institute Zhengzhou University Academy of Medical SciencesZhengzhouHenan ProvinceChina

Thalamic hemorrhage can lead to the development of central post-stroke *** in histone acetylation levels,which are regulated by histone deacetylases,affect the excitability of neurons surrounding the hemorrhagic ***,the regulato ry mechanism of histone deacetylases in central post-stroke pain remains unclea ***,we show that iron overload leads to an increase in histone deacetylase 2expression in damaged ventral posterolateral nucleus *** this increase restored histone H3 acetylation in the Kcna2 promoter region of the voltage-dependent potassium(Kv)channel subunit gene in a rat model of central post-stroke pain,thereby increasing Kcna2expression and relieving central ***,in the absence of nerve injury,increasing histone deacetylase 2 expression decreased Kcna2expression,decreased Kv current,increased the excitability of neurons in the ventral posterolateral nucleus area,and led to neuropathic pain ***,treatment with the iron chelator deferiprone effectively reduced iron overload in the ventral posterolateral nucleus after intracerebral hemorrhage,reversed histone deacetylase 2 upregulation and Kv1.2 downregulation,and alleviated mechanical hypersensitivity in central post-stroke pain *** results suggest that histone deacetylase 2 upregulation and Kv1.2 downregulation,mediated by iron overload,are important factors in central post-stroke pain pathogenesis and co uld se rve as new to rgets for central poststroke pain treatment.

关键词： central post-stroke pain hemorrhagic stroke histone deacetylase iron overload voltage-gated potassium ion channel 1.2

DMSP/OLS夜光数据的珠三角碳排放时空差异性分析

在线全文

学校读者我要写书评

暂无评论

遥感学报 2022年第9期26卷 1824-1837页

作者：王艳军王孟杰柳林李少春林云浩湖南科技大学测绘遥感信息工程湖南省重点实验室湘潭411201 湖南科技大学地理空间信息技术国家地方联合工程实验室湘潭411201 湖南科技大学资源环境与安全工程学院湘潭411201 广州大学地理科学与遥感学院公共安全地理信息分析中心广州510006 辛辛那提大学地理系美国辛辛那提OH45221-0131

碳排放时空分布及其异质性是生态环境保护和气候变化监测研究的重要课题。本文针对珠三角城市群碳排放空间分布的精细分析,基于DMSP/OLS夜间灯光影像与土地利用数据,研究了2000年—2013年珠三角城市群碳排放时空差异性,揭示了不同地市... 详细信息

碳排放时空分布及其异质性是生态环境保护和气候变化监测研究的重要课题。本文针对珠三角城市群碳排放空间分布的精细分析,基于DMSP/OLS夜间灯光影像与土地利用数据,研究了2000年—2013年珠三角城市群碳排放时空差异性,揭示了不同地市不同用地类型的碳排放时空分布特征、碳排放增长趋势和强度趋势。结果表明:(1) 2000年—2013年珠三角城市群碳排放总量一直处于增长阶段,但受2008年金融危机影响由高速增长转为缓慢增长阶段;(2)人均碳排放强度在2008年金融危机后增长速度减缓;(3)单位GDP碳排放强度在经历了2005年—2008年小幅增长阶段之后,整体呈现降低趋势;(4)地均碳排放强度方面,工矿用地的地均碳排放强度由2008年金融危机前的增长阶段过渡到危机后的降低阶段,而城镇用地的地均碳排放强度一直处于持续增长阶段。研究发现,珠三角城市群碳排放在2008年金融危机前后具有明显的时空差异性,城镇用地碳排放持续增长将成为碳减排的关键问题,本研究可为碳排放估算预测、节能减排及生态环境保护提供科学参考。

关键词：碳排放时空分布 DMSP/OLS夜间灯光影像土地利用数据精细化

在线全文

学校读者我要写书评

暂无评论

基于联合特征映射的端到端三维模型草图检索

计算机辅助设计与图形学学报 2019年第12期31卷 2056-2065页

作者：白静孔德馨周文惠王梦杰北方民族大学计算机科学与工程学院银川750021 宁夏智能信息与大数据处理重点实验室银川750021

在草图-三维模型检索任务中,草图具有类内多样性,三维模型具有复杂性,且草图-三维模型之间存在巨大的域间的差异性,这些特点的相互作用使得基于草图的三维模型检索任务变得特别困难.针对这一问题,提出一种基于联合特征映射的端到端三维... 详细信息

在草图-三维模型检索任务中,草图具有类内多样性,三维模型具有复杂性,且草图-三维模型之间存在巨大的域间的差异性,这些特点的相互作用使得基于草图的三维模型检索任务变得特别困难.针对这一问题,提出一种基于联合特征映射的端到端三维模型草图检索框架.首先将三维模型转化为一组二维视图,建立跨域数据的共享数据空间;然后通过网络权值共享,建立端到端的三元度量学习网络,实现跨域数据草图和视图的联合特征映射;最后基于联合特征分布,提出4种草图-三维模型相似评价算法来实现草图-三维模型的检索.在大型公共数据集SHREC2013和SHREC2014上的检索精度分别为81.8%和75.6%,比现有算法在7项检索指标PR曲线,NN,FT,ST,E,DCG和MAP上都有所提升,检索性能突出.

关键词：基于草图的检索三维模型检索联合特征分布度量学习深度学习端到端网络