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RE-SEGNN:recurrent semantic evidence-aware graph neural network for temporal knowledge graph forecasting

Science China(Information Sciences) 2025年

作者： Wenyu CAI mengfan li Xuanhua SHI Yuanxin FAN Quntao ZHU Hai JIN National Engineering Research Center for Big Data Technology and System Services Computing Technology and System Lab Cluster and Grid Computing Lab School of Computer Science and TechnologyHuazhong University of Science and Technology

Temporal knowledge graph(TKG) reasoning, has seen widespread use for modeling real-world events, particularly in extrapolation settings. Nevertheless, most previous studies are embedded models, which require both entity and relation embedding to make predictions, ignoring the semantic correlations among different entities and relations within the same timestamp. This can lead to random and nonsensical predictions when unseen entities or relations occur. Furthermore, many existing models exhibit limitations in handling highly correlated historical facts with extensive temporal depth. They often either overlook such facts or overly accentuate the relationships between recurring past occurrences and their current counterparts. Due to the dynamic nature of TKG, effectively capturing the evolving semantics between different timestamps can be *** address these shortcomings, we propose the recurrent semantic evidenceaware graph neural network(RE-SEGNN), a novel graph neural network that can learn the semantics of entities and relations simultaneously. For the former challenge, our model can predict a possible answer to missing quadruples based on semantics when facing unseen entities or relations. For the latter problem, based on an obvious established force, both the recency and frequency of semantic history tend to confer a higher reference value for the current. We use the Hawkes process to compute the semantic trend, which allows the semantics of recent facts to gain more attention than those of distant facts. Experimental results show that RE-SEGNN outperforms all SOTA models in entity prediction on 6 widely used datasets, and 5 datasets in relation prediction. Furthermore, the case study shows how our model can deal with unseen entities and relations.

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Architectural proteins for the formation and maintenance of the 3D genome

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Science China(life Sciences) 2020年第6期63卷 795-810页

作者： mengfan li Jingbo Gan Yuao Sun Zihan Xu Junsheng Yang Yujie Sun Cheng li Peking-Tsinghua Center for life Sciences Academy for Advanced Interdisciplinary Studies School of Life Sciences Peking UniversityBeijing 100871China State Key Laboratory of Membrane Biology School of Life Sciences Biomedical Pioneering Innovation Center (BIOPIC) Peking UniversityBeijing 100871China Center for Statistical Science Center for Bioinformatics School of Life Sciences Peking UniversityBejjing 100871China

Eukaryotic genomes are densely packaged into hierarchical three-dimensional(3D) structures that contain information about gene regulation and many other biological processes. With the development of imaging and sequencing-based technologies, 3D genome studies have revealed that the high-order chromatin structure is composed of hierarchical levels, including chromosome territories, A/B compartments, topologically associated domains, and chromatin loops. However, how this chromatin architecture is formed and maintained is not completely clear. In this review, we introduce experimental methods to investigate the 3D genome, review major architectural proteins that regulate 3D chromatin organization in mammalian cells, such as CTCF(CCCTC-binding factor), cohesin, lamins, and transcription factors, and discuss relevant mechanisms such as phase separation.

关键词： 3D genome architectural protein Hi-C

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CVT-Based Asynchronous BCI for Brain-Controlled Robot Navigation

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Cyborg and Bionic Systems 2023年第1期4卷 318-329页

作者： mengfan li Ran Wei Ziqi Zhang Pengfei Zhang Guizhi Xu Wenzhe liao State Key Laboratory of Reliability and Intelligence of Electrical Equipment School of Health Sciences and Biomedical EngineeringHebei University of Technology300132 TianjinChina Hebei Key Laboratory of Bioelectromagnetics and Neuroengineering 300132 TianjinChina Tianjin Key Laboratory of Bioelectromagnetic Technology and Intelligent Health 300132 TianjinChina School of Artificial Intelligence Hebei University of Technology300132 TianjinChina

Brain-computer interface(BCI)is a typical direction of integration of human intelligence and robot *** control is an essential form of combining human and robot agents in a common task,but still faces a lack of freedom for the human *** paper proposes a Centroidal Voronoi Tessellation(CVT)-based road segmentation approach for brain-controlled robot navigation by means of asynchronous *** electromyogram-based asynchronous mechanism is introduced into the BCI system for self-paced control.A novel CVT-based road segmentation method is provided to generate optional navigation goals in the road area for arbitrary goal *** event-related potential of the BCI is designed for target selection to communicate with the *** robot has an autonomous navigation function to reach the human selected goals.A comparison experiment in the single-step control pattern is executed to verify the effectiveness of the CVT-based asynchronous(CVT-A)BCI *** subjects participated in the experiment,and they were instructed to control the robot to navigate toward a destination with obstacle avoidance *** results show that the CVT-A BCI system can shorten the task duration,decrease the command times,and optimize navigation path,compared with the single-step ***,this shared control mechanism of the CVT-A BCI system contributes to the promotion of human and robot agent integration control in unstructured environments.

关键词： robot agent Robot

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Crystal-phase-controlled PtSn intermetallic nanowires for efficient methanol oxidation

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Science China Chemistry 2024年第12期67卷 4142-4148页

作者： Siyu Cao mengfan li Zihan Guo li Gong Yangfan Lu Wenhua Zhang Yu Ni Lei Gao Chao Ma Hongwen Huang College of Materials Science and Engineering Changsha University of Science and TechnologyChangsha 410114China College of Materials Science and Engineering Hunan UniversityChangsha 410082China Zhejiang Provincial Engineering Research Center of Oxide Semiconductors for Environmental and Optoelectronic Applications Institute of WenzhouZhejiang UniversityWenzhou 325006China State Key Laboratory of Silicon Materials School of Materials Science and EngineeringZhejiang UniversityHangzhou 310027China Department of Chemical Physics University of Science and Technology of ChinaHefei 230026China China Power Engineering Consulting Group Co. LTDBeijing 100120China Shenzhen Research Institute of Hunan University Shenzhen 518055China

Developing highly efficient Pt-based methanol oxidation reaction(MOR)catalysts is pivotal for direct methanol fuel *** engineering of nanomaterials offers a promising strategy to improve their catalytic performance,yet achieving phase modulation in one-dimensional nanowires(NWs)remains a great ***,we report a facile and one-pot synthesis approach for the crystal-phase-controlled Pt-Sn intermetallic nanowires(NWs),realizing the crystal-phases regulation of face-centered cubic Pt_(3)Sn intermetallic NWs(FCC-Pt_(3)Sn INTNWs)and hexagonal close-packed Pt Sn intermetallic NWs(HCP-PtSn INTNWs)by adjusting the amounts of Sn ***,the FCC-Pt_(3)Sn INTNWs exhibit high mass and specific activities of 6.4 A mg_(Pt)^(-1)and 11.8 mA cm^(-2),respectively,surpassing its counterparts,the HCP-PtSn INTNWs and commercial Pt/C *** a 10,000 s durability test,the FCC-Pt_(3)Sn INTNWs still maintain a mass activity of 5.6 A mg_(Pt)^(-1),which is 24.3 times higher than that of commercial Pt/C *** dramatic enhancement of MOR performance is primarily attributed to the phasecontrolled structure and accelerated removal of CO intermediates(CO*).Theoretical calculations and CO stripping experiments demonstrate that the FCC-Pt_(3)Sn INTNWs lower the energy barrier for converting CO*into COOH*by reducing CO*binding and enhancing OH adsorption,thus significantly improving the MOR activity,CO tolerance,and stability.

关键词： Pt-Sn intermetallic nanowires crystal phase methanol oxidation reaction anti-CO poisoning

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Nuclear peripheral chromatin-lamin B1 interaction is required for global integrity of chromatin architecture and dynamics in human cells

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Protein & Cell 2022年第4期13卷 258-280页

作者： Lei Chang mengfan li Shipeng Shao Chen li Shanshan Ai Boxin Xue Yingping Hou Yiwen Zhang Ruifeng li Xiaoying Fan Aibin He Cheng li Yujie Sun State Key Laboratory of Membrane Biology School of Life Sciencesand Biomedical Pioneering Innovation Center(BIOPIC)Peking UniversityBeijing 100871China Peking-Tsinghua Center for life Sciences Academy for Advanced Interdisciplinary StudiesPeking UniversityBeijing 100871China Center for Bioinformatics School of Life SciencesPeking UniversityBeijing 100871China Institute of Molecular Medicine Beijing Key Laboratory of Cardiometabolic Molecular MedicinePeking UniversityBeijing 100871China Center for Statistical Science Peking UniversityBeijing 100871China Bioland Laboratory(Guangzhou Regenerative Medicine and Health Guangdong Laboratory) Guangzhou 510530China

The eukaryotic genome is folded into higher-order conformation accompanied with constrained dynamics for coordinated genome ***,the molecular machinery underlying these hierarchically organized three-dimensional(3D)chromatin architecture and dynamics remains poorly *** by combining imaging and sequencing,we studied the role of lamin B1 in chromatin architecture and *** found that lamin B1 depletion leads to detachment of lamina-associated domains(LADs)from the nuclear periphery accompanied with global chromatin redistribution and ***,the interchromosomal as well as inter-compartment interactions are increased,but the structure of topologically associating domains(TADs)is not *** live-cell genomic loci tracking,we further proved that depletion of lamin B1 leads to increased chromatin dynamics,owing to chromatin decompaction and redistribution toward *** together,our data suggest that lamin B1 and chromatin interactions at the nuclear periphery promote LAD maintenance,chromatin compaction,genomic compartmentalization into chromosome territories and A/B compartments and confine chromatin dynamics,supporting their crucial roles in chromatin higher-order structure and chromatin dynamics.

关键词： lamin B1 3D genome Hi-C chromatin dynamics chromosome territories A/B compartments livecell imaging super-resolution imaging

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烯丙基芳香化合物的电化学选择性氧化酯化

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有机化学 2024年第3期44卷 1005-1012页

作者：李梦帆程旭南京大学化学化工学院南京210023

报道了烯丙基芳基化合物的电化学氧化酯化方法,通过同时活化苄位+烯丙位的C—H和C—C键,合成了一系列苯甲酸酯类化合物.本反应展现了良好的化学选择性,优先在苄位+烯丙位发生氧化,而其它的苄位C—H键则保持稳定.该反应在中性条件下进行... 详细信息

报道了烯丙基芳基化合物的电化学氧化酯化方法,通过同时活化苄位+烯丙位的C—H和C—C键,合成了一系列苯甲酸酯类化合物.本反应展现了良好的化学选择性,优先在苄位+烯丙位发生氧化,而其它的苄位C—H键则保持稳定.该反应在中性条件下进行,无需酸碱添加剂,可以适用叔醇酯的构建,同时避免酯和醇存在下的转移酯化副反应.

关键词：烯丙基苄基电化学酯化

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无载波幅度相位调制无线光通信系统研究

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红外与激光工程 2017年第12期46卷 144-151页

作者：柯熙政李梦帆西安理工大学自动化与信息工程学院陕西西安710048

无载波幅度相位(Carrierless Amplitude and Phase,CAP)调制是一种数字化方式的正交幅度调制(Quadrature Amplitude Modulation,QAM)。由于CAP调制具有频谱利用率高、成本低、复杂度小等优点,所以逐渐成为实现短距离高速光通信系统的一... 详细信息

无载波幅度相位(Carrierless Amplitude and Phase,CAP)调制是一种数字化方式的正交幅度调制(Quadrature Amplitude Modulation,QAM)。由于CAP调制具有频谱利用率高、成本低、复杂度小等优点,所以逐渐成为实现短距离高速光通信系统的一种备选方案。首先通过比较CAP调制和QAM的功率谱分析了这两种调制方式的特性,然后在大气信道仿真模型(Gamma-Gamma光强起伏分布模型)条件下,基于Matlab仿真分析了滤波器滚降系数,滤波器长度和采样时钟偏移对CAP调制无线光通信系统性能的影响并给出最优参数值。由仿真可知,采样时钟偏移会引起接收端信号的相位偏移,所以需要在接收端对相位畸变进行一定的补偿,文中也对后期所需的均衡算法进行了一些研究,希望能对以后CAP系统的设计有所帮助。最后对仿真结果进行了实验验证。

关键词：无线光通信无载波幅度相位调制正交幅度调制系统性能相位偏移

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具体与抽象图形对N200和P300电位的影响研究

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生物医学工程学杂志 2020年第3期37卷 427-433,441页

作者：李梦凡杨光河北工业大学电气工程学院电工装备可靠性与智能化国家重点实验室天津300132 河北工业大学电气工程学院天津市生物电工与智能健康重点实验室天津300132

增大事件相关电位的幅值是提高P300等经典事件相关电位范式下的脑-机接口系统辨识意图准确率的重要方法之一,此类脑-机接口系统常以符号或者被控对象作为视觉刺激,但是何种视觉刺激能够获得更明显的事件相关电位仍然未知。本文设计方形... 详细信息

增大事件相关电位的幅值是提高P300等经典事件相关电位范式下的脑-机接口系统辨识意图准确率的重要方法之一,此类脑-机接口系统常以符号或者被控对象作为视觉刺激,但是何种视觉刺激能够获得更明显的事件相关电位仍然未知。本文设计方形、箭头和机器人附加箭头这三种视觉刺激,分析图片的具体程度对N200和P300电位的影响,并采用支持向量机辨识该诱发电位来对比不同刺激下的脑-机接口性能。结果显示,与方形相比,机器人附加箭头和箭头都在额叶诱发出幅值更大的N200电位(P=1.6×10-3,P=4.2×10-2)和潜伏期更长的P300电位(P=2.2×10-3,P=1.9×10-2)。机器人附加箭头将方形和箭头的N200电位幅值数值分别从3.12μV和5.19μV提升至7.21μV(P=1.6×10-3,P=8.9×10-2),单次准确率从59.95%和61.67%提升至74.45%(P=2.1×10-2,P=1.6×10-2),单次信息传输率从35.00 bits/min和35.98 bits/min提升至56.71 bits/min(P=2.6×10-2,P=1.6×10-2)。本研究表明图形的具体性会影响N200电位和P300电位,箭头虽然能够表征图片的含义并诱发电位,但是机器人附加箭头所包含的信息与人的经验相关度更大,有助于获得更高的电位幅值。该研究可为脑-机接口的视觉刺激界面优化设计提供新的思路。

关键词：具体图形抽象图形视觉刺激 N200 P300

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Research on Brain-Controlled Robot System Based on Intelligent Decision Fusion Shared Control

Research on Brain-Controlled Robot System Based on Intellige...

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第43届中国控制会议

作者： Ziqi Zhang mengfan li Jingyu Wang Chunlong Wu State Key Laboratory of Reliability and Intelligence of Electrical Equipment School of Health Science and Biomedical EngineeringHebei University of Technology Hebei Key Laboratory of Bioelectromagnetics and Neuroengineering Tianjin Key Laboratory of Bioelectromagnetic Technology and Intelligent Health School of Health Science and Biomedical Engineering Hebei University of Technology School of Mechanical Engineering Hebei University of Technology

As machine intelligence continues to advance, the role of Human-Robot Collaboration（HRC） control technology becomes increasingly prominent. In current control systems, it is crucial to consider how to appropriately integrate human decision-making with robotic decision-making on the foundation of machine intelligence. This integration aims to fully leverage the respective decision-making strengths of humans and robots. Brain-Computer Interface（BCI）, as a technology that utilizes human biological signals to recognize human intentions, can accurately convey human decisions to the system. Addressing the issue of limited interaction in brain-controlled robot navigation in unstructured environments, this study proposes a navigation road segmentation method based on the U-net algorithm. This method extracts the effective navigation area and subdivides it,enabling the selection of navigation points *** robot, controlled based on the movease architecture, accomplishes automatic navigation to reach the user-selected navigation points. Through experiments comparing with the single-step shared control mode（SS-SC）, the effectiveness of the intelligent decision fusion shared control（IDF-SC） mode is validated. Eight participants took part in the experiment, where they were instructed to control the robot to navigate towards the endpoint and complete obstacle avoidance tasks. The experimental results indicate that the IDF-SC mode can shorten task duration, reduce the number of commands, and optimize navigation paths. The research outcomes of this project contribute to enhancing the safety and intelligence in the field of human-machine collaboration.

关键词： Human-robot collaboration Brain-computer interface U-net network shared control

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价值转形研究:基于TSSI模型的拓展分析

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当代经济研究 2020年第7期 61-72页

作者：李梦凡西南财经大学经济学院成都611130

将TSSI两期模型拓展至多期,探索其系统性特征,基于矩阵特征分解和佩隆-弗洛宾尼斯定理发现,若投入矩阵具有生产性,那么按照TSSI多期程序的价值向量、生产价格向量逐渐收敛于常数向量;基期的生产价格设定不会影响收敛存在性,但具体选择... 详细信息

将TSSI两期模型拓展至多期,探索其系统性特征,基于矩阵特征分解和佩隆-弗洛宾尼斯定理发现,若投入矩阵具有生产性,那么按照TSSI多期程序的价值向量、生产价格向量逐渐收敛于常数向量;基期的生产价格设定不会影响收敛存在性,但具体选择会影响收敛值大小,且通过价值-生产价格偏差在时间上的累积效应来表现的;确定基期偏差,该累积效应也收敛于常向量。数例研究表明,总生产价格与总价值相等、总利润与总剩余价值相等在所有时期成立;一般利润率动态变化,但随转化过程收敛至稳态,价值向量与生产价格向量也在收敛,偏差向量随之收敛。

关键词：价值转形 TSSI P-F定理收敛

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