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界面聚合法制备低压中空纤维纳滤复合膜

膜科学与技术 2024年第2期44卷 80-88页

作者：张梁王涛姚冬雪关悦孟建强天津工业大学省部共建分离膜与膜过程国家重点实验室材料科学与工程学院天津300387

现有中空纤维纳滤膜在实际应用中能耗较高.采用干湿法纺丝技术制备聚砜(PSf)中空纤维超滤膜作为基膜,分别选用哌嗪(PIP)和均苯三甲酰氯(TMC)为水相单体和有机相单体,通过界面聚合工艺的优化,成功制备了低压中空纤维纳滤膜.用扫描电子显... 详细信息

现有中空纤维纳滤膜在实际应用中能耗较高.采用干湿法纺丝技术制备聚砜(PSf)中空纤维超滤膜作为基膜,分别选用哌嗪(PIP)和均苯三甲酰氯(TMC)为水相单体和有机相单体,通过界面聚合工艺的优化,成功制备了低压中空纤维纳滤膜.用扫描电子显微镜和原子力显微镜对膜表面形貌进行表征,用傅里叶变换红外光谱仪和X射线光电子能谱仪分析膜表面的化学结构和元素组成,测试了复合膜的表面水接触角、Zeta电位、截留分子量和孔径分布,研究了单体浓度、界面聚合反应时间以及测试压力对复合膜性能的影响并确定了最佳的工艺条件.结果表明,优化的低压中空纤维纳滤膜具有低交联度的聚酰胺功能层,在0.2 MPa的测试压力下,纯水通量达到(16.0±0.4)L/(m^(2)·h),对质量浓度为1 g/L的盐溶液的截留率为Na_(2)SO_(4)(94.2%±0.9%)>MgSO_(4)(92.2%±0.9%)>MgCl_(2)(51.0%±0.5%)>NaCl(9.5%±0.3%),表现出优异的Na_(2)SO_(4)/NaCl选择性.

关键词：界面聚合纳滤中空纤维膜低压薄层复合膜

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用于钙离子全光囚禁的离子囚禁装置研究

仪器仪表学报 2024年第2期45卷 102-111页

作者：陈正王淼黄垚管桦高克林中国科学院精密测量科学与技术创新研究院武汉430071 中国科学院大学北京100049

随着离子光钟技术的飞速发展,由离子光钟中用来囚禁离子的射频场带来的微运动效应对其性能的影响也越来越不可忽略。为彻底消除这一效应,提出了全光囚禁离子光钟的实验方案。针对这一实验方案,设计并搭建了用于钙离子全光囚禁的离子囚... 详细信息

随着离子光钟技术的飞速发展,由离子光钟中用来囚禁离子的射频场带来的微运动效应对其性能的影响也越来越不可忽略。为彻底消除这一效应,提出了全光囚禁离子光钟的实验方案。针对这一实验方案,设计并搭建了用于钙离子全光囚禁的离子囚禁装置。该装置是采用刀片型离子阱设计,能够实现剩余力仅有10^(-20) N量级的高精度的杂散电场补偿;具备6 mm的通关孔径,很好满足了全光囚禁实验中偶极囚禁激光的通过需求;基于改良的螺旋谐振器设计搭建的射频系统能够实现在9.33(1)MHz较低射频频率下的稳定耦合;结合高达10^(-9) Pa的真空制备和装配导电玻窗的真空腔体,可以实现长时间的离子囚禁。为全光囚禁钙离子提供了实验基础,对光学囚禁离子光钟的实现具有重大意义。

关键词：离子光钟全光囚禁离子阱射频真空腔

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大中型水库建设洲滩土地淹没处理补偿探讨

中国农村水利水电 2024年第6期 180-184,192页

作者：官耀辉湖南省水利水电勘测设计规划研究总院有限公司湖南长沙410007

大中型水库淹没处理是工程建设的重要基础,涉及到国家、集体和个人的利益,具有政策性强、现场情况复杂、利害关系交织等特点,其中洲滩土地权属确定、地类认定和补偿费用计算争议较大,从湘资沅澧四水大中型水库工程建设淹没处理的实践,... 详细信息

大中型水库淹没处理是工程建设的重要基础,涉及到国家、集体和个人的利益,具有政策性强、现场情况复杂、利害关系交织等特点,其中洲滩土地权属确定、地类认定和补偿费用计算争议较大,从湘资沅澧四水大中型水库工程建设淹没处理的实践,提出了洲滩土地权属确定、地类认定的有关法规政策依据,以及洲滩土地补偿费和相关税费计算的路径和方法,供水利水电工程征地补偿和移民安置工作者参考。

关键词：洲滩土地权属地类法规政策淹没处理

淮河上游径流变化多元影响因子敏感性及贡献率分析

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应用基础与工程科学学报 2024年第3期32卷 801-812页

作者：孟钰徐文静管新建严登华郑州大学水利与交通学院河南郑州450001 黄河实验室(郑州大学) 河南郑州450001

解析径流变化与自然、人为因素的响应关系,对流域水资源安全及管理具有重要意义.构建了一个以多元影响因素为输入、以径流为输出的长短期记忆网络(Long Short-Term Memory,LSTM)模型,以建立包括气候变化与人类活动在内的多元影响因子与... 详细信息

解析径流变化与自然、人为因素的响应关系,对流域水资源安全及管理具有重要意义.构建了一个以多元影响因素为输入、以径流为输出的长短期记忆网络(Long Short-Term Memory,LSTM)模型,以建立包括气候变化与人类活动在内的多元影响因子与径流的响应关系,进而分析多元影响因子与径流之间的敏感性与贡献率.以淮河上游为研究区进行实例研究,结果表明:径流对人类影响因素敏感性高于气象因素,对水库塘坝库容具有最高敏感性;突变后各因素平均敏感性增大.气象与人类活动对径流的贡献率分别为55%、45%.其中,水库塘坝库容、降水量、净辐射的变化为径流减少的主导因素.合理的水利工程建设与生态修复布局,对径流调节起到有益作用.研究成果为径流变化规律与成因辨识、流域下垫面保护及水安全保障提供科学参考与决策辅助.

关键词：径流变化贡献率敏感性 LSTM模型突变检验淮河上游

Radiomics-based quantitative contrast-enhanced CT analysis of abdominal lymphadenopathy to differentiate tuberculosis from lymphoma

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Precision Clinical Medicine 2024年第1期7卷 87-89页

作者： meng-Ting Shen Xi Liu Yue Gao Rui Shi Li Jiang Jin yao Department of Radiology West China HospitalSichuan UniversityChengdu 610041China Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education) Department of RadiologyPeking University Cancer Hospital and InstituteBeijing 100142China

Dear Editor,Tuberculosis(TB)is a significant cause of morbidity and mortality in developing countries,with a global burden of∼10.0 million cases in *** accounts for 8.4%of TB cases globally,ranking third after India and Indonesia[1].Abdominal TB is a common extrapulmonary manifestation,often presenting as *** differentiation between abdominal tuberculosis lymphadenopathy(ATBL)and lymphoma holds significance for treatment decisions and prognosis.

关键词： tuberculosis lymphoma abdominal

Pien Tze Huang Inhibits Proliferation of Colorectal Cancer Cells through Suppressing PNO1 Expression and Activating p53/p21 Signaling Pathway

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Chinese Journal of Integrative Medicine 2024年第6期30卷 515-524页

作者： CAO Liu-jing LIU Li-ya CHEN You-qin HAN Yu-ying WEI Li-hui yao meng-ying FANG Yi WU Mei-zhu CHENG Ying Thomas J.Sferra LIU Hui-xin LI Li PENG Jun SHEN A-ling Clinical Research Institute the Second Affiliated Hospital&Academy of Integrative MedicineFujian University of Traditional Chinese MedicineFuzhou350122China Fujian Key Laboratory of Integrative Medicine in Geriatrics Fujian University of Traditional Chinese MedicineFuzhou350122China Department of Pediatrics Case Western Reserve University School of MedicineUH Rainbow Babies and Children’s HospitalClevelandOH44106USA Innovation and Transformation Center Fujian University of Traditional Chinese MedicineFuzhou350122China Department of Health Management Fujian Provincial HospitalShengli Clinical College of Fujian Medical UniversityFuzhou000000China

ObjectiveTo explore the regulatory effect of Pien Tze Huang (PZH) on targeting partner of NOB1 (PNO1) and it’s down-stream mediators in colorectal cancer (CRC) *** polymerase chain reaction was performed to determine mRNA levels of PNO1, TP53, and CDKN1A. Western blotting was performed to determine protein levels of PNO1, p53, and p21. HCT-8 cells were transduced with a lentivirus over-expressing PNO1. Colony formation assay was used to detect cell survival in PNO1 overexpression of HCT-8 cells after PZH treatment. Cell-cycle distribution, cell viability and cell apoptosis were performed to identify the effect of PNO1 overexpression on cell proliferation and apoptosis of HCT-8 cells after PZH treatment. Xenograft BALB/c nude mice bearing HCT116 cells transduced with sh-PNO1 or sh-Ctrl lentivirus were evaluated. Western blot assay was performed to detect PNO1, p53, p21 and PCNA expression in tumor sections. Terminal deoxynucleotidyl transferase dUTP nick end labling (TUNEL) assay was used to determine the apoptotic cells in *** treatment decreased cell viability, down-regulated PNO1 expression, and up-regulated p53 and p21 expressions in HCT-8 cells (P<0.05). PNO1 overexpression attenuated the effects of PZH treatment, including the expression of p53 and p21, cell growth, cell viability, cell cycle arrest and cell apoptosis in vitro (P<0.05). PNO1 knockdown eliminated the effects of PZH treatment on tumor growth, inhibiting cell proliferation inhibition and apoptosis induction in vivo (P<0.05). Similarly, PNO1 knockdown attenuated the effects of PZH treatment on the down-regulation of PNO1 and up-regulation of p53 and p21 in vivo (P<0.05).ConclusionThe mechanism by which PZH induces its CRC anti-proliferative effect is at least in part by regulating the expression of PNO1 and its downstream targets p53 and p21.

关键词： colorectal cancer Pien Tze Huang Chinese medicine partner of NOB1 proliferation p53/p21 pathway

Magnetic resonance imaging-based radiomics model for preoperative assessment of risk stratification in endometrial cancer

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World Journal of Clinical Cases 2024年第26期12卷 5908-5921页

作者： Zhi-yao Wei Zhe Zhang Dong-Li Zhao Wen-Ming Zhao Yuan-guang meng Department of Obstetrics and Gynecology Seventh Medical Center of Chinese People’s Liberation Army General HospitalBeijing 100700China National Genomics Data Center and Chinese Academy of Sciences Key Laboratory of Genome Sciences and Information Beijing Institute of GenomicsChinese Academy of Sciences and China National Center for BioinformationBeijing 100700China

BACKGROUND Preoperative risk stratification is significant for the management of endometrial cancer(EC)*** based on magnetic resonance imaging(MRI)in combination with clinical features may be useful to predict the risk grade of *** To construct machine learning models to predict preoperative risk stratification of patients with EC based on radiomics features extracted from *** The study comprised 112 EC *** participants were randomly separated into training and validation groups with a 7:3 *** regression analysis was applied to uncover independent clinical *** predictors were then used to create a clinical *** radiomics features from the T2-weighted imaging and diffusion weighted imaging sequences of MRI images,the Mann-Whitney U test,Pearson test,and least absolute shrinkage and selection operator analysis were employed to evaluate the relevant radiomic features,which were subsequently utilized to generate a radiomic *** machine learning strategies were used to construct radiomic models that relied on the screening *** logistic regression method was used to construct a composite nomogram that incorporated both the radiomic signature and clinical independent risk *** Having an accuracy of 0.82 along with an area under the curve(AUC)of 0.915[95%confidence interval(CI):0.806-0.986],the random forest method trained on radiomics characteristics performed better than *** predictive accuracy of radiomics prediction models surpassed that of both the clinical nomogram(AUC:0.75,95%CI:0.611-0.899)and the combined nomogram(AUC:0.869,95%CI:0.702-0.986)that integrated clinical parameters and radiomic *** The MRI-based radiomics model may be an effective tool for preoperative risk grade prediction in EC patients.

关键词： Endometrial cancer Risk stratification Radiomics Machine learning Nomogram

Food-Borne Poisoning Accident from Amanitin Toxin in Wild Mushrooms—Xingtai City,Hebei Province,China,2023

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China CDC weekly 2024年第3期6卷 56-59页

作者： Baopu Lv Liang Liu Hao Xiao Qingbing meng Rui Zhang Yaqing An Yingli Jin Yu Ma Hengbo Gao Yongkai Li Qian He Yutao Zhang Changqing Liu Xiaoyan Luo Xiaomin Xu Fenshuang Zheng Yingping Tian Hongshun Zhang Dongqi yao Emergency Department The Second Hospital of Hebei Medical UniversityShijiazhuang CityHebei ProvinceChina National Institute of Occupational Health and Poison Control Chinese Centre for Disease Control and PreventionBeijingChina Hebei Provincial Center for Disease Control and Prevention Shijiazhuang CityHebei ProvinceChina Zhejiang Provincial Center for Disease Control and Prevention Hangzhou CityZhejiang ProvinceChina Emergency Department The Affiliated Hospital of Yunnan UniversityKunming CityYunnan ProvinceChina

What is already known about this topic?Fatal poisonings caused by wild mushrooms containing amanita toxins pose a significant threat in the southern regions of *** toxins primarily induce gastrointestinal symptoms initially,which are then followed by potentially life-threatening acute liver *** is added by this report?This report contributes to the existing knowledge on these cases of poisoning by documenting the second occurrences in Hebei Province and the first occurrences in Xingtai *** individuals reported consuming wild mushrooms from the same origin,and laboratory tests confirmed the presence ofα-amanitin in their blood *** are the implications for public health practice?This underscores the risk associated with the collection and consumption of amanita toxin-containing mushrooms in *** is important to note that the identification of toxic and non-toxic mushrooms should not solely rely on personal experience or appearance.

关键词： Hebei consuming initially

Measurement of atmospheric non-reciprocity effects for satellite-based two-way time-frequency transfer

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Photonics Research 2024年第6期12卷 1274-1282页

作者： TING ZENG QI SHEN YUAN CAO JIAN-YU guan meng-ZHE LIAN JIN-JIAN HAN LEI HOU JIAN LU XIN-XIN PENG MIN LI WEI-YUE LIU JIN-CAI WU YONG WANG JUAN YIN JI-GANG REN HAI-FENG JIANG QIANG ZHANG CHENG-ZHI PENG JIAN-WEI PAN Hefei National Research Center for Physical Sciences at the Microscale and School of Physical Sciences University of Science and Technology of ChinaHefei 230026China Shanghai Research Center for Quantum Science and CAS Center for Excellence in Quantum Information and Quantum Physics University of Science and Technology of ChinaShanghai 201315China Hefei National Laboratory University of Science and Technology of ChinaHefei 230094China Faculty of Information Science and Engineering Ningbo UniversityNingbo 315211China Key Laboratory of Space Active Opto-Electronic Technology Shanghai Institute of Technical PhysicsChinese Academy of SciencesShanghai 200083China Xinjiang Astronomical Observatory Chinese Academy of SciencesUrumqi 830011China

Future optical clock networks will require high-precision optical time-frequency transfer between satellites and ground ***,due to atmospheric turbulence,satellite motion and time delay between the satellite–ground transmission links will cause spatial and temporal variations,respectively,resulting in the breakdown of the time-of-flight reciprocity on which optical two-way time-frequency transfer is ***,we experimentally simulate the atmospheric effects by two-way spatio-temporally separated links between two stationary terminals located 113 km apart and measure the effects for optical two-way time-frequency *** experiment shows that the effect on the link instability is less than 2.3×10^(−19) at 10,000 *** indicates that when the link instability of satellite-ground optical time-frequency transfer is on the order of 10^(−19),it is not necessary to consider the atmospheric non-reciprocity effects.

关键词： breakdown transfer satellite