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Toxic effect of acrylamide on the development of hippocampal neurons of weaning rats

Neural Regeneration Research 2017年第10期12卷 1648-1654页

作者： Sheng-min Lai Zi-ting Gu meng-meng zhao Xi-xia Li Yu-xin Ma Li Luo Jing Liu Department of Human Anatomy and Histoembryology School of Basic CoursesGuangdong Pharmaceutical UniversityGuangzhouGuangdong ProvinceChina

Although numerous studies have examined the neurotoxicity of acrylamide in adult animals,the effects on neuronal development in the embryonic and lactational periods are largely unknown.Thus,we examined the toxicity of acrylamide on neuronal development in the hippocampus of fetal rats during pregnancy.Sprague-Dawley rats were mated with male rats at a 1：1 ratio.Rats were administered 0,5,10 or 20 mg/kg acrylamide intragastrically from embryonic days 6–21.The gait scores were examined in pregnant rats in each group to analyze maternal toxicity.Eight weaning rats from each group were also euthanized on postnatal day 21 for follow-up studies.Nissl staining was used to observe histological change in the hippocampus.Immunohistochemistry was conducted to observe the condition of neurites,including dendrites and axons.Western blot assay was used to measure the expression levels of the specific nerve axon membrane protein,growth associated protein 43,and the presynaptic vesicle membrane specific protein,synaptophysin.The gait scores of gravid rats significantly increased,suggesting that acrylamide induced maternal motor dysfunction.The number of neurons,as well as expression of growth associated protein 43 and synaptophysin,was reduced with increasing acrylamide dose in postnatal day 21 weaning rats.These data suggest that acrylamide exerts dose-dependent toxic effects on the growth and development of hippocampal neurons of weaning rats.

关键词： nerve regeneration acrylamide hippocampus neurons developmental toxicity growth associated protein 43 synaptophysin weaning rats dentate gyrus protein developmental neurobiology neural regeneration

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Attractor for the Extensible Beam Equation with Nonlocal Weak Damping on Time–Dependent Space

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Acta Mathematica Sinica,English Series 2024年第4期40卷 1115-1126页

作者： Chun Xiang zhao Feng Juan meng Institute of Applied System Analysis Jiangsu UniversityZhenjiang 212013P.R.China School of Mathematics and Physics Jiangsu University of TechnologyChangzhou 213001P.R.China

In this article,we consider the long-time behavior of extensible beams with nonlocal weak damping:ε(t)u_(tt)+Δ^(2)u-m(‖▽u‖^(2))Δu+‖u_(t)‖^(p_(u_(t)))+f(u)=h,whereε(t)is a decreasing function vanishing at infinity.Within the theory of process on time-dependent spaces,we investigate the existence of the time-dependent attractor by using the Condition(C_(t))method and more detailed estimates.The results obtained essentially improve and complete some previous works.

关键词： Time-dependent attractor extensible beams equation nonlocal weak damping

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UNCONDITIONAL ERROR ANALYSIS OF VEMS FOR A GENERALIZED NONLINEAR SCHRODINGER EQUATION

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Journal of Computational Mathematics 2024年第2期42卷 500-543页

作者： meng Li Jikun zhao Shaochun Chen School of Mathematics and Statistics Zhengzhou UniversityZhengzhouHenan 450001China

In this work,we focus on the conforming and nonconforming leap-frog virtual element methods for the generalized nonlinear Schrodinger equation,and establish their unconditional stability and optimal error estimates.By constructing a time-discrete system,the error between the solutions of the continuous model and the numerical scheme is separated into the temporal error and the spatial error,which makes the spatial error τ-independent.The inverse inequalities in the existing conforming and new constructed nonconforming virtual element spaces are utilized to derive the L^(∞)-norm uniform boundedness of numerical solutions without any restrictions on time-space step ratio,and then unconditionally optimal error estimates of the numerical schemes are obtained naturally.What needs to be emphasized is that if we use the pre-existing nonconforming virtual elements,there is no way to derive the L^(∞)-norm uniform boundedness of the functions in the nonconforming virtual element spaces so as to be hard to get the corresponding inverse inequalities.Finally,several numerical examples are reported to confirm our theoretical results.

关键词： Conforming and nonconforming Virtual element methods Leap-frog scheme Generalized nonlinear Schrodinger system Unconditionally optimal error estimates

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Glutamicibacter nicotianae AT6:A new strain for the efficient biodegradation of tilmicosin

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Journal of Environmental Sciences 2024年第8期142卷 182-192页

作者： Huijuan Li Hao Zhou Liling Fan Long meng Yanyun zhao Lanmei zhao Bo Wang College of Chemical and Biological Engineering Shandong University of Science and TechnologyQingdao 266590China College of Chemistry and Chemical Engineering Heze UniversityHeze 274015China College of Safety and Environmental Engineering Shandong University of Science and TechnologyQingdao 266590China

The degradation of tilmicosin(TLM),a semi-synthetic 16-membered macrolide antibiotic,has been receiving increasing attention.Conventionally,there are three tilmicosin degradation methods,and among them microbial degradation is considered the best due to its high efficiency,eco-friendliness,and low cost.Coincidently,we found a new strain,Glutamicibacter nicotianae sp.AT6,capable of degrading high-concentration TLM at 100 mg/L with a 97%removal efficiency.The role of tryptone was as well investigated,and the results revealed that the loading of tryptone had a significant influence on TLM removals.The toxicity assessment indicated that strain AT6 could efficiently convert TLM into less-toxic substances.Based on the identified intermediates,the degradation of TLM by AT6 processing through two distinct pathways was then proposed.

关键词： Tilmicosin Glutamicibacter nicotianae Biodegradation Degradation pathway Pharmaceutical wastewater

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Enhanced potassium storage of carbon nanofibers as binderfree anodes enabled by coupling ultra-small amorphous Sb_(2)O_(3),graphene modification and sulfur doping

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Rare Metals 2024年第1期43卷 51-64页

作者： zhao Huang Yu-Kang Lou Lin Peng Yuan Peng meng-meng Wang Ming Zhang College of Railway Transportation Hunan University of TechnologyZhuzhou 412007China College of Semiconductors(College of Integrated Circuits) Changsha Semiconductor Technology and Application Innovation Research InstituteHunan UniversityChangsha 410082China Key Laboratory for Micro-Nano Optoelectronic Devices of Ministry of Education College of Semiconductors(College of Integrated Circuits)Hunan UniversityChangsha 410082China

Considering the intrinsic advantages of natural copiousness and cost-effectiveness of potassium resource,potassium-ion batteries(KIBs) are booming as prospective alternatives to lithium-ion batteries(LIBs) in large-scale energy storage scenarios. Nevertheless, lacking desirable electrodes for reversibly hosting the bulky K+hinders the widespread application of KIBs, and it needs to be urgently solved. Hereon, the porous S-doped Sb_(2)O_(3)-graphene-carbon(SAGC) nanofibers are manufactured through an adjustable and facile approach, which involves electrospinning, in situ etching and sulfuration. The synthesized SAGC is featured by the ultra-small amorphous Sb_(2)O_(3) homogeneously wrapped inside the carbon matrix, as well as the co-incorporation of graphene and sulfur. Tentatively,the SAGC nanofiber sheets are applied as binder-free anodes for KIBs, exhibiting a prominent cycling life(256.72 m Ah·g^(-1) over 150 cycles at 100 m A·g^(-1)) and rate·g^(-1) over 100 cycles at 1 A·g^(-1)). The positive synergy among all the active components accounts for the distinguished performances of the SAGC. By reinforcing the tolerability to the swelling stress, producing the valid electrochemical active sites, and promoting the charge transferring for reversible K+uptake, the SAGC finally renders the excellent cyclability, capacity, and rate capability. Moreover, the extrinsic electrochemical pseudocapacitance characteristics induced by the porous carbon substrate elevate the K-storage capacity of the SAGC as well. It is hoped that the conclusions drawn may offer new insights into a direction for the high-performance binderfree KIB anodes.

关键词： S-doped Sb_(2)O_(3)-graphene-carbon Nanofibers Binder-free Anodes Potassium-ion batteries

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Efficient degradation of aqueous dichloromethane by an enhanced microbial electrolysis cell:Degradation kinetics,microbial community and metabolic mechanisms

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Journal of Environmental Sciences 2024年第5期139卷 150-159页

作者： meng Wu Di zhao Bing Gu ZiruWang Jun Hu Zhiliang Yu Jianming Yu College of Environment College of Biotechnology and BioengineeringCollaborative Innovation Center of Yangtze River Delta Region Green PharmaceuticalsZhejiang University of TechnologyHangzhou 310014China Shentuo Environment(Hangzhou)Co.Ltd. Hangzhou 311121China Zhejiang Tianyi Environmental Co.Ltd. Hangzhou 310000China

Dichloromethane(DCM)has been listed as a toxic and harmful water pollutant,and its re moval needs attention.Microbial electrolysis cells(MECs)are viewed as a promising alterna tive for pollutant removal,which can be strengthened from two aspects:microbial inocula tion and acclimation.In this study,the MEC for DCM degradation was inoculated with the ac tive sludge enhanced by Methylobacterium rhodesianum H13(strain H13)and then acclimated in the form of a microbial fuel cell(MFC).Both the introduction of strain H13 and the initi ation in MFC form significantly promoted DCM degradation.The degradation kinetics were fitted by the Haldane model,with V_(max),K_(h),K_(i)and v_(max)values of 103.2 mg/L/hr,97.8 mg/L268.3 mg/L and 44.7 mg/L/hr/cm^(2),respectively.The cyclic voltammogram implies that DCM redox reactions became easier with the setup of MEC,and the electrochemical impedance spectrogram shows that the acclimated and enriched microbes reduced the charge transfe resistance from the electrode to the electrolyte.In the biofilm,the dominant genera shifted from Geobacter to Hyphomicrobium in acclimation stages.Moreover,Methylobacterium played an increasingly important role.DCM metabolism mainly occurred through the hydrolytic glutathione S-transferase pathway,given that the gene dcmA was identified rather than the dhlA and P450/MO.The exogenous electrons facilitated the reduction of GSSG,directly o indirectly accelerating the GSH-catalyzed dehalogenation.This study provides support fo the construction of an efficient and stable MEC for DCM removal in water environment.

关键词： Dichloromethane Microbial electrolysis cells Metabolic pathways Electron transfer Degradation kinetics

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CONSERVATIVE CONFORMING AND NONCONFORMING VEMS FOR FOURTH ORDER NONLINEAR SCHRODINGER EQUATIONS WITH TRAPPED TERM

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Journal of Computational Mathematics 2024年第2期42卷 454-499页

作者： meng Li Jikun zhao Zhongchi Wang Shaochun Chen School of Mathematics and Statistics Zhengzhou UniversityZhengzhou 450001China School of Computer Science and Engineering Beihang universityBeijing 100083China

This paper aims to construct and analyze the conforming and nonconforming virtual element methods for a class of fourth order nonlinear Schrodinger equations with trapped term.We mainly consider three types of virtual elements,including H^(2) conforming virtual element,C^(0) nonconforming virtual element and Morley-type nonconforming virtual element.The fully discrete schemes are constructed by virtue of virtual element methods in space and modified Crank-Nicolson method in time.We prove the mass and energy conservation,the boundedness and the unique solvability of the fully discrete schemes.After introducing a new type of the Ritz projection,the optimal and unconditional error estimates for the fully discrete schemes are presented and proved.Finally,two numerical examples are investigated to confirm our theoretical analysis.

关键词： H^(2)conforming virtual element C^(0)nonconforming virtual element Morleytype nonconforming virtual element Nonlinear Schrodinger equation Conservation Convergence

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Energy-absorbing porous materials:Bioinspired architecture and fabrication

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Nano Research 2024年第2期17卷 679-690页

作者： Junheng zhao meng Li Jiewei Chen Weiwei Gao Hao Bai State Key Laboratory of Chemical Engineering College of Chemical and Biological EngineeringZhejiang UniversityHangzhou 310058China Department of Polymer Science and Engineering Zhejiang UniversityHangzhou 310058China

Energy-absorbing materials are widely used in transportations,sports,and the military applications.Particularly,porous materials,including natural and artificial materials,have attracted tremendous attentions due to their light weight and excellent energy absorption capability.This review summarizes the recent progresses in the natural and artificial energy-absorbing porous materials.First,we review the typical natural porous materials including cuttlebone,bighorn sheep horn,pomelo peel,and sunflower stem pith.The architectures,energy absorption abilities,and mechanisms of these typical natural materials and their bioinspired materials are summarized.Then,we provide a review on the fabrication methods of artificial energy-absorbing porous materials,such as conventional foaming and three-dimensional(3D)printing.Finally,we address the challenges and prospects for the future development of energy-absorbing porous materials.More importantly,our review provides a direct guidance for the design and fabrication of energy-absorbing porous materials required for various engineering applications.

关键词： energy-absorbing porous materials natural materials natural structures bioinspired materials

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Effect of Nozzle Inclination Angle on Fuel-Air Mixing and Combustion in a Heavy Fuel Engine

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Fluid Dynamics & Materials Processing 2024年第2期20卷 365-382页

作者： Zhigang Wang Bin Zheng Peidong zhao Baoli Wang Fanyan meng Wenke Xu Jian meng School of Transportation and Vehicle Engineering Shandong University of TechnologyZibo255049China

Heavy-fuel engines are widely used in UAVs(Unmanned Autonomous Vehicles)because of their reliability and high-power density.In this study,a combustion model for an in-cylinder direct injection engine has been imple-mented using the AVL FIRE software.The effects of the angle of nozzle inclination on fuel evaporation,mixture distribution,and combustion in the engine cylinder have been systematically studied at 5500 r/min and consider-ing full load cruise conditions.According to the results,as the angle of nozzle inclination increases,the maximum combustion explosion pressure in the cylinderﬁrst increases and then it decreases.When the angle of nozzle incli-nation is less than 45°,the quality of the mixture in the cylinder and the combustion performance can be improved by increasing the angle.When the angle of nozzle inclination is greater than 45°,however,the mixture unevenness increases slightly with the angle,leading to a deterioration of the combustion performances.When the angle of nozzle inclination is between 35°and 55°,the overall combustion performance of the engine is rela-tively good.When the angle of nozzle inclination is 45°,the combustion chamber’s geometry and the cylinder’s airﬂow are well matched with the fuel spray,and the mixture quality is the best.Compared with 25°,the peak heat release rate increases by 20%,and the maximum combustion burst pressure increases by 5.5%.

关键词： Aviation heavy fuel piston engine nozzle inclination angle combustion fuel-air mixing

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A Large-Scale Group Decision Making Model Based on Trust Relationship and Social Network Updating

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工程与科学中的计算机建模(英文) 2024年第1期138卷 429-458页

作者： Rongrong Ren Luyang Su Xinyu meng Jianfang Wang meng zhao School of Business Administration Northeastern UniversityShenyang110819China School of Management Northeastern University at QinhuangdaoQinhuangdao066004China School of Modern Logistics Shanxi Vocational University of Engineering Science and TechnologyTaiyuan030031China Business School Sichuan UniversityChengdu610064China

With the development of big data and social computing,large-scale group decisionmaking(LGDM)is nowmerging with social networks.Using social network analysis(SNA),this study proposes an LGDM consensus model that considers the trust relationship among decisionmakers(DMs).In the process of consensusmeasurement:the social network is constructed according to the social relationship among DMs,and the Louvain method is introduced to classify social networks to form subgroups.In this study,the weights of each decision maker and each subgroup are computed by comprehensive network weights and trust weights.In the process of consensus improvement:A feedback mechanism with four identification and two direction rules is designed to guide the consensus of the improvement process.Based on the trust relationship among DMs,the preferences are modified,and the corresponding social network is updated to accelerate the consensus.Compared with the previous research,the proposedmodel not only allows the subgroups to be reconstructed and updated during the adjustment process,but also improves the accuracy of the adjustment by the feedbackmechanism.Finally,an example analysis is conducted to verify the effectiveness and flexibility of the proposed method.Moreover,compared with previous studies,the superiority of the proposed method in solving the LGDM problem is highlighted.

关键词： Large-scale group decision making social network updating trust relationship group consensus feedback mechanism

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