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Effects of different processing methods on the quality of Polygonatum cyrtonema Hua

TMR Modern Herbal Medicine 2024年第2期7卷 28-34页

作者： Xin-Ning Zhang Shuang-Hui Shi Jun-Li Zhang Fan-Miao Kong Hai-Ting Zhu Si-yuan Ma yu-Feng Hu Ming-Rui Jiang Hui-Nan Wang meng-Lin Wang Xiao-Tong Wei Jing-Qiu Zhang Nan Sun meng-yu chen Qian-Qian Liu Ying-Zi Wang School of Chinese Materia Medica Beijing University of Chinese MedicineBeijing 102488China

Background:In this study,we explored the effects of different processing methods on the quality of Polygonatum cyrtonema Hua(PC),and the role of Huangjiu in the processing ***:The sensory characteristics of the crude product,steamed product,and wine-processed product of PC were *** colorimeter was used to analyze the chromatic values of three different processed products on *** the same time,the contents of the water extract and alcohol extract were measured *** content of three different processing Polygonatum Polysaccharide(PCP)was determined using 0.2%anthrone-sulfuric *** correlation difference between the chromatic values and chemical composition of different PC products was analyzed using various analytical ***:The surface colors gradually deepened,the sweetness increased,the viscosity strengthened,and the tongue-numbing sensation disappeared after PC *** contents of extract and L^(*) gradually decreased from the crude to the steamed to the wine-processed product,consistent with the pattern of surface color ***,E^(*)ab gradually *** content of PCP was crude product>wine-processed product>steamed *** results of multivariate statistical analysis showed that the samples processed for crude,steamed,and wine-processed product were clustered into three *** correlation analysis showed that L^(*)and E^(*)ab were highly significant positively correlated with the content of PCP,and a*was significantly negatively correlated with the content of ***:The results showed that the wine-processed product had the best *** internal quality of the PC was correlated with its characteristics and chromatic *** this study,we investigated the internal and external quality of three different products of PC in order to provide a reference for further research on the impact of different processing methods on PC quality,the standardization of PC processing,and the

关键词： Polygonatum cyrtonema Hua different products chemical composition chromatic value characteristics

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Microstructure and mechanical properties of a cast TRIP-assisted multiphase stainless steel

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China Foundry 2024年第3期21卷 221-228页

作者： meng-xin Wang Zi-xiang Wu Jing-yu He Xiang chen School of Materials Science and Engineering Tsinghua UniversityBeijing 100084China Key Laboratory for Advanced Materials Processing Technology Ministry of EducationBeijing 100084China

Stainless steels are used in a wide range of complex environments due to their excellent corrosion *** stainless steels can offer an excellent combination of strength,toughness and corrosion resistance due to the coexistence of different *** microstructure and mechanical properties of a novel cast multiphase stainless steel,composed of martensite,ferrite,and austenite,were investigated following appropriate heat treatment processes:solution treatment at 1,050℃ for 0.5 h followed by water quenching to room temperature,and aging treatment at 500℃ for 4 h followed by water quenching to room *** show reversed austenite is formed by diffusion of Ni element during aging process,and the enrichment of Ni atoms directly determines the mechanical stability of *** austenite with a lower Ni content undergoes a martensitic transformation during plastic *** tensile strength of the specimen exceeds 1,100 MPa and the elongation exceeds 24%after solid solution,and further increases to 1,247 MPa and 25%after aging *** enhancement is due to the TRIP effect of austenite and the precipitation of the nanoscale G-phase pinning dislocations in ferrite and martensite.

关键词： multiphase stainless steel mechanical properties TRIP effect reversed austenite G-phase

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Six types of spin solitons in three-component Bose-Einstein condensates

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Communications in Theoretical Physics 2024年第6期76卷 57-65页

作者： yu-Hao Wang Ling-Zheng meng Li-chen Zhao School of Physics Northwest UniversityXi'an 710127China School of Science Xi'an Technological UniversityXi'an 710032China Peng Huanwu Center for Fundamental Theory Xi'an 710127China

Exact analytical solutions are good candidates for studying and explaining the dynamics of solitons in nonlinear *** further extend the region of existence of spin solitons in the nonlinearity coefficient space for the spin-1 Bose-Einstein *** types of spin soliton solutions can be obtained,and they exist in different *** analysis and numerical simulation results indicate that three types of spin solitons are stable against weak *** non-integrable properties of the model can induce shape oscillation and increase in speed after the collision between two spin *** results further enrich the soliton family for non-integrable models and can provide theoretical references for experimental studies.

关键词： Bose-Einstein condensate non-integrable spin soliton exact analytical solution

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The effect of Ti and Zr content on the structure,mechanics and energy-release characteristics of Ti—Zr—Ta alloys

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Defence Technology（防务技术） 2024年第1期31卷 343-350页

作者： Jia-yu meng Jing-zhi He Bin Zhang Jin chen Shun Li Dun Niu yu Tang Xi’an Modern Chemistry Research Institute Xi'an710065China College of Aerospace Science and Engineering National University of Defense TechnologyChangsha410073China

Energetic structural materials(ESMs)are a new type of structural materials with bearing and damage *** this work the microstructure,mechanical properties and energy release characteristics of multi-element Ti-Zr-Ta alloys with good casting performance were *** microstructure of the Ti_(x)ZrTa alloys gradually change from BCC+HCP to single BCC structure with the increase of *** the Ti_(2)Zr_(y)Ta alloys was still uniform and single BCC structure with the increase of *** evolution of microstructure and composition then greatly affect the mechanical properties and energy-release characteristics of Ti-Zr-Ta *** synergistic effect of dual phase structure increases the fracture strain of Ti_(x)ZrTa(x=0.2,0.5)with the Ti content decreases,while the fracture strain of Ti_(x)ZrTa(x=2.0,3.0,4.0)gradually increase with the Ti content increases caused by the annihilation of the obstacles for dislocation *** as Zr content increases,the fracture strain of Ti_(2)Zr_(y)Ta alloys decrease,then the oxidation reaction rate and fragmentation degree gradually *** higher oxidation rate and the lager exposed oxidation area jointly leads the higher releasing energy efficiency of Ti_(x)ZrTa alloys with low Ti content and Ti_(2)Zr_(y)Ta alloys with high Zr content.

关键词： Energetic structural materials Ti-Zr-Ta Multi-element alloy Energy release characteristics

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Azocalixarenes: a scaffold of universal excipients with high efficiency

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Science China Chemistry 2024年第5期67卷 1697-1706页

作者： yu-Xin yue Yi-Lin Lin meng-meng chen Han-Wen Tian Rong Ma Ze-Han Wang Fang-yuan chen yu-chen Pan Dong-Sheng Guo College of Chemistry State Key Laboratory of Elemento-Organic ChemistryKey Laboratory of Functional Polymer Materials(Ministry of Education)Frontiers Science Center for New Organic MatterCollaborative Innovation Center of Chemical Science and Engineering(Tianjin)Nankai UniversityTianjin 300071China

Excipients are important components of pharmaceutical preparations that affect their quality, safety, and efficacy. Macrocyclic receptors are a family of supramolecular excipients with several advantages, including molecular-level protection, small sizes,fast kinetics of host-guest recognition, and modular construction. With the continuous advances in the medical field, personalized and precision medicine requires the development of excipients with low dosages, integrated modifying effects, universality,and controlled release. To meet these requirements, we have developed a new family of macrocyclic excipients based on calixarenes by integrating their covalent(broad chemical design space) and noncovalent(wide range of substrates) ***, azocalixarenes(Azo CAs) were designed, showing high binding affinities to a broad spectrum of active pharmaceutical ingredients(APIs), selectivity to interferents, and responsiveness to hypoxic microenvironments. Due to their highly efficient and controllable recognition, Azo CAs serve as low-dose excipients for 30 APIs. Molecular encapsulation by Azo CAs results in the integrated modification of the physicochemical properties of APIs, including solubility, stability, bioavailability,and biocompatibility. Moreover, Azo CAs can be reduced by azoreductases overexpressed in hypoxic microenvironments,leading to the controlled release of APIs. Collectively, Azo CA excipients have broad application prospects for a series of diseases such as enteritis, arthritis, stroke, cancer, bacterial infection and kidney injury, with diverse therapeutic modalities,including chemotherapy, photodynamic therapy, photothermal therapy, immunotherapy, boron neutron capture therapy, radiotherapy, fluorescence imaging, and their combinations.

关键词： supramolecular chemistry host-guest systems excipient calixarene molecular recognition

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Enhanced cyclic stability of partially disordered spinel cathodes through direct fluorination with gaseous fluorine

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Rare Metals 2024年第4期43卷 1635-1646页

作者： Yong-Nian Ma Ling-chen Kong Shao-Shan chen Yong Wang Li-Dong Sun Cong Peng meng-meng Qin yu Li Wei Feng Tianjin Key Laboratory of Composite and Functional Materials School of Materials Science and EngineeringTianjin UniversityTianjin300072China Institute of Advanced Technology and Equipment Beijing University of Chemical TechnologyBeijing100029China

Spinel-type cathodes are considered an optimal substitute for conventional layered oxide cathodes owing to their use of inexpensive and earth-abundant manganese as the redox-active ***,the introduction of cation disorder can effectively suppress the detrimental two-phase reaction to realize high capacities in a wide voltage ***,the continuous capacity decay during cycles has hindered the widespread application of these cathode *** fluorides exhibit excellent electrochemical stability at high voltage;therefore,in this study,the direct F2 gas reaction with a partially disordered spinel cathode(Li_(1.6)Mn_(1.6)O_(3.7)F_(0.3,)LMOF1.6)was initially applied to investigate the impacts of fluorination on the surface structure and electrochemical *** inorganic fluorinated layer,mainly containing LiF,was distributed uniformly on the surface of LMOF1.6nanoparticles after fluorination for an appropriate time without the turbulence caused by the valency of manganese cation,which improved the capacity retention and rate capability by the suppression of structural damage,parasitic reaction,and cation *** LMOF1.6cathode fluorinated for 0.5 h exhibited a capacity of283.6 mAh·g^(-1)at 50 mA·g^(-1)and an enhanced capacity retention of 29.6%after 50 cycles in the voltage range of1.5-4.8 V,as compared to the pristine LMOF1.6 with only27.9%capacity retention.

关键词： Spinel-type cathodes Direct fluorination Capacity retention ability High rate capability

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Learning Robust Locomotion for Bipedal Robot via Embedded Mechanics Properties

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Journal of Bionic Engineering 2024年第3期21卷 1278-1289页

作者： yuanxi Zhang Xuechao chen Fei meng Zhangguo yu Yidong Du Junyao Gao Qiang Huang School of Mechatronical Engineering Beijing Institute of TechnologyBeijing100081China Key Laboratory of Biomimetic Robots and Systems Ministry of EducationBeijing100081China

Reinforcement learning(RL)provides much potential for locomotion of legged *** to the gap between simulation and the real world,achieving sim-to-real for legged robots is ***,the support polygon of legged robots can help to overcome some of these *** robot has a considerable support polygon,followed by bipedal robot with actuated feet,and point-footed bipedal robot has the smallest support ***,despite the existing sim-to-real gap,most of the recent RL approaches are deployed to the real quadruped robots that are inherently more stable,while the RL-based locomotion of bipedal robot is challenged by zero-shot sim-to-real *** for the point-footed one that gets better dynamic performance,the inevitable tumble brings extra barriers to sim-to-real ***,the crux of this type of problem is the difference of mechanics properties between the physical robot and the simulated one,making it difficult to play the learned skills well on the physical bipedal *** this paper,we introduce the embedded mechanics properties(EMP)based on the optimization with Gaussian processes to RL training,making it possible to perform sim-to-real transfer on the BRS1-P robot used in this work,hence the trained policy can be deployed on the BRS1-P without any *** validate the performance of the learning-based BRS1-P on the condition of disturbances and terrains not ever learned,demonstrating the bipedal locomotion and resistant performance.

关键词： Bipedal robot Reinforcement learning Sim-to-real Mechanics properties

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Rational Design of Ruddlesden-Popper Perovskite Ferrites as Air Electrode for Highly Active and Durable Reversible Protonic Ceramic Cells

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Nano-Micro Letters 2024年第9期16卷 308-324页

作者： Na yu Idris Temitope Bello Xi chen Tong Liu Zheng Li yufei Song meng Ni Department of Building and Real Estate Research Institute for Sustainable Urban Development(RISUD)and Research Institute for Smart Energy(RISE)The Hong Kong Polytechnic UniversityHung HomKowloonHong KongPeople’s Republic of China The Hong Kong Polytechnic University Shenzhen Research Institute Shenzhen 518057GuangdongPeople’s Republic of China Department of Mechanical and Aerospace Engineering The Hong Kong University of Science and TechnologyClear Water BayHong KongPeople’s Republic of China

Reversible protonic ceramic cells(RePCCs)hold promise for efficient energy storage,but their practicality is hindered by a lack of high-performance air electrode ***-Popper perovskite Sr_(3)Fe_(2)O_(7−δ)(SF)exhibits superior proton uptake and rapid ionic conduction,boosting ***,excessive proton uptake during RePCC operation degrades SF’s crystal structure,impacting *** study introduces a novel A/B-sites co-substitution strategy for modifying air electrodes,incorporating Sr-deficiency and Nb-substitution to create Sr_(2.8)Fe_(1.8)Nb_(0.2)O_(7−δ)(D-SFN).Nb stabilizes SF’s crystal,curbing excessive phase formation,and Sr-deficiency boosts oxygen vacancy concentration,optimizing oxygen *** D-SFN electrode demonstrates outstanding activity and durability,achieving a peak power density of 596 mW cm^(−2)in fuel cell mode and a current density of−1.19 A cm^(−2)in electrolysis mode at 1.3 V,650℃,with excellent cycling *** approach holds the potential for advancing robust and efficient air electrodes in RePCCs for renewable energy storage.

关键词： Reversible protonic ceramic cells Air electrode Ruddlesden-Popper perovskite Hydration Oxygen reduction reaction

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Drug delivery systems for colorectal cancer chemotherapy

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Chinese Chemical Letters 2024年第2期35卷 163-175页

作者： Wen chen Kun Shi Yan yu Peipei Yang Zhongwu Bei Dong Mo Liping yuan meng Pan yu chen Zhiyong Qian Department of Biotherapy Cancer Center and State Key Laboratory of BiotherapyWest China HospitalSichuan UniversityChengdu 610041China

Colorectal cancer causes the third most common type of malignant tumors with high morbidity and *** is currently one of the most effective and common treatments for colorectal ***,the poor water solubility of some chemotherapeutics,untargeted drug delivery,and the undesirable systemic side effects of conventional treatment remain the major issues for colorectal cancer ***,drug delivery systems(DDS)based on biomaterials have been widely investigated and found to be capable of resolving those issues with good ***,the main goal of this review is to summarize and discuss the progress and potential advantages of different DDS for colorectal cancer *** not only reviewed the nanocarriers used to improve the solubility of chemotherapeutics,including liposomes,micelles,and nanoparticles,but also discussed targeted DDS based on specific ligand-receptor recognition and tumor microenvironmental stimulus ***,locally administered systems based on hydrogels and microspheres,which have been shown to increase drug accumulation at the tumor site while decreasing systemic toxicity,were also *** provides a good option for improving the efficacy of chemotherapy in the treatment of colorectal cancer.

关键词： Colorectal cancer Chemotherapy Drug delivery systems Solubility Targeted Local administration

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Cellular Cd^(2+)fluxes in roots confirm increased Cd availability to rice(Oryza sativa L.)induced by soil acidifications

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Journal of Environmental Sciences 2024年第5期139卷 516-526页

作者： Xiaoyi Sun meng Wang Luyao Qin Lei yu Jing Wang Han Zheng Wenneng Zhou Shibao chen State Key Laboratory of Efficient Utilization of Arid and Semi-arid Arable Land in Northern China/Institute of Agricultural Resources and Regional Planning Chinese Academy of Agricultural SciencesBeijing 100081China Guangdong Provincial Key Laboratory of Water Quality Improvement and Ecological Restoration for Watersheds School of EcologyEnvironment and ResourcesGuangdong University of TechnologyGuangzhou 510006China

Soil acidifications become one of the main causes restricting the sustainable development of agriculture and causing issues of agricultural product *** order to explore the effect of different acidification on soil cadmium(Cd)availability,soil pot culture and hydroponic(soil potting solution extraction)were applied,and non-invasive micro-test technique(NMT)was *** three different soil acidification processes were simulated,including direct acidification by adding sulfuric acid(AP1),acid rain acidification(AP2)by adding artificial simulated acid rain and excessive fertilization acidification by adding(NH_(4))_(2)SO_(4)(AP3).The results showed that for direct acidification(AP1),DTPA-Cd concentration in field soils in Liaoning(S1)and Zhejiang(S2)increased by 0.167-0.217 mg/kg and 0.181-0.346 mg/kg,respectively,compared with control *** soil pH decreased by 0.45 units in S1,the Cd content of rice stems,leaves and roots increased by 0.48 to 6.04 mg/kg and 2.58 to 12.84mg/kg,respectively,When the pH value of soil S1 and S2 decreased by 0.20 units,the average velocity of Cd^(2+)at 200μm increased by 10.03-33.11 pmol/cm~2/sec and 21.33-52.86pmol/cm^(2)/sec,respectively,and followed the order of AP3>AP2>*** summary,different acidification measures would improve the effectiveness of Cd,under the same pH reduction condition,fertilization acidification increased Cd availability most significantly.

关键词： Soil acidification Cadmium Non-invasive micro-test technique Bioavailability

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