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Meta-analysis of the effect of continuing nursing on the psychological status of rectal cancer patients undergoing stoma

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Nursing Communications 2022年第1期6卷 109-116页

作者： meng-xi gao Lyu Cheng Ai-Ying Zhang Wei Fan Tian-Tian Gai Yan Wang Department of Graduate Tianjin University of Traditional Chinese MedicineTianjin 301600China Department of Nursing Tianjin University of Traditional Chinese MedicineTianjin 301600China.

Objective:To systematically evaluate the effect of continuous nursing on the psychological status of rectal cancer patients undergoing stoma.Methods:Five databases including China HowNet,Chongqing Weipu Chinese Science and Technology Database,Wanfang Database,Embase and PubMed were searched.Randomized controlled trials were collected on the effect of continuing nursing on the psychological status of rectal cancer patients undergoing stoma.The searching time was from the establishment of the database to March 30,2019.RevMan 5.3 software was used to analyze the bias risk of the study after two researchers independently screened the researchers,extracted the data and evaluated the bias risk of the study.Results:A total of 15 studies were included.Meta-analysis showed that the continuing nursing group improved anxiety[MD=-10.89,95%CI(-13.52,-8.26),P<0.00001],depression[MD=-4.78,95%CI(-5.77,-3.80,P<0.00001],fear[MD=-6.06,95%CI(-7.70,-4.43),P<0.00001],hostile[MD=-7.00,95%CI(-13.62,-0.38),P=0.04<0.05],somatization[MD=-7.63,95%CI(-13.49,-1.77),P=0.01<0.05].The self-care ability[MD=38.24,95%CI(35.38,41.11),P<0.00001]was superior to the routine nursing group.Conclusion:Continuous nursing has more advantages than routine nursing,and it can improve the negative psychological state of rectal cancer patients undergoing stoma.Due to the limitations of the quantity and quality of the included studies,the above conclusions need to be verified by more high-quality studies.

关键词： continuous nursing care rectal cancer stoma systematic evaluation

Effect of Baduanjin on rehabilitation of patients with coronary heart disease:A meta-analysis of 8 randomized controlled trials

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TMR Integrative Nursing 2019年第4期3卷 133-139页

作者： Tian-Tian Gai Wei Fan meng-xi gao Yu Cui Yan Wang Department of Graduate Tianjin University of Traditional Chinese MedicineTianjinChina Department of Nursing Tianjin University of Traditional Chinese MedicineTianjinChina

背景:八段锦作为国家体育总局推荐的传统康复运动之一,被广泛应用于冠心病的防治中。为了系统地评价八段锦对冠心病患者康复的影响,计算机检索The Cochrane Library、PubMed、EMbase、Web of science、CBM、CNKI、万方数据库和维普数据... 详细信息

背景:八段锦作为国家体育总局推荐的传统康复运动之一,被广泛应用于冠心病的防治中。为了系统地评价八段锦对冠心病患者康复的影响,计算机检索The Cochrane Library、PubMed、EMbase、Web of science、CBM、CNKI、万方数据库和维普数据库,搜集八段锦应用于冠心病患者的随机对照试验,检索时限均为建库至2018年11月份。由2位评价员独立筛选文献、提取资料并评价纳入研究的偏倚风险后,采用RevMan5.3进行Meta分析。结果:纳入8个随机对照实验,共615例患者。相比对照组,八段锦可提高患者的射血分数[MD=2.99,95%CI(1.54,4.45),P<0.001],增加六分钟步行距离[SMD=2.29,95%CI(0.44,4.13),P=0.02],焦虑自评量表、抑郁自评量表评分降低[MD=-5.06,95%CI(-6.63,-3.49),P<0.001]、[MD=-5.12,95%CI(-8.73,-1.50)P=0.006]。结论:当前研究结果显示,八段锦能改善患者心肺功能、提高患者运动耐量、缓解患者不良情绪。

关键词：中医八段锦冠心病 Meta分析

Systematic evaluation of Kang-ai injection combined with chemotherapy versus chemotherapy alone in the treatment of ovarian cancer

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Drug Combination Therapy 2019年第1期1卷 19-30页

作者： meng-xi gao Ai-Ying Zhang Tian-Tian Gai Wei Fan Yan Wang Graduate school Tianjin University of Traditional Chinese herbs School of nursing Tianjin University of Traditional Chinese herbs

Objective:This study was conducted to evaluate the clinical efficacy and safety of Kang-ai injection combined with chemotherapy in the treatment of ovarian cancer.Methods:the databases of VIP,CNKI,WanFang,CBM,Pub Med,Cochrane Library and EMBASE were searched to collect the randomized controlled trials(RCTs)of Kang-ai injection,combined with chemotherapy versus chemotherapy alone for the treatment of ovarian cancer.The retrieval time was from the database setup to December 20,2018.After two researchers independently screened the researches,extracted data and evaluated the risk of the included studies,the RevMan 5.3 software was used for analysis.A total of 8 RCTS were included.Results:Results showed that patients in Kang-ai injection combined with chemotherapy group were superior to the conventional chemotherapy group patients in total effective rate[RR=1.31,95%CI(1.11,1.54),P=0.001],quality of life[RR=1.69,95%CI(1.35,2.13),P<0.001],leukopenia[RR=0.63,95%CI(0.51,0.77),P<0.001],nausea and vomiting[RR=0.41,95%CI(0.24,0.70),P=0.001],decreased hemoglobin[RR=0.50,95%CI(0.28,0.88),P=0.002],and thrombocytopenia[RR=0.45,95%CI(0.24,0.85),P=0.01].Conclusion:Kang-ai injection combined with chemotherapy for ovarian cancer is better than chemotherapy alone in improving total effective rate and quality of life,reducing the incidence of adverse reactions.Limited by the number and quality of included studies,the above conclusions are yet to be verified by more high-quality studies.

关键词： Kang-ai injection Chemotherapy Ovarian cancer Total efficiency Quality of life Adverse reactions

Identification of core compositions of traditional Chinese medicine for Seborrheic Dermatitis using data mining techniques

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Medical Data Mining 2019年第4期2卷 134-141页

作者： meng-xi gao Ai-Ying Zhang Zhi-Dan Cao Wei Fan Tian-Tian Gai Yan Wang Department of Graduate Tianjin University of Traditional Chinese MedicineTianjinChina School of nursing Tianjin University of Traditional Chinese MedicineTianjinChina

Objective:To explore the clinical medication rule of seborrheic dermatitis in modern Chinese medicine by data mining,in order to benefit the clinical treatment of seborrheic dermatitis in traditional Chinese medicine.Methods:From January 1,2010 to September 4,2019,articles on Chinese medicine for seborrheic dermatitis were searched systematically in CNKI,VIP and Wan Fang databases.Prescription databases were established through the Chinese Medicine Inheritance assistant system to mine and analyze the rules of data.Results:69 researches were screened out,72 prescriptions for seborrheic dermatitis.13 drugs were used more than or equal to 15 times,and 9 pairs of commonly used drugs with correlation coefficient above 0.045 were selected.Six core combinations and two new prescriptions were obtained.Conclusion:Data mining method was used to analyze the high-frequency drugs and drug pairs,which reflected the treatment principle of clearing heat and removing dampness,nourishing blood and moistening dryness,promoting qi and strengthening spleen in the clinical treatment of seborrheic dermatitis,and provided more intuitive research evidence for the follow-up clinical treatment.

关键词： Seborrheic dermatitis Medication rule Traditional Chinese medicine Data mining

Comprehensive evaluation of rare case:From diagnosis to treatment of a sigmoid Schwannoma:A case report

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World Journal of Gastrointestinal Oncology 2024年第1期16卷 244-250页

作者： Jing-Yi Li xi-Zhuang gao Jian Zhang xiang-Zheng meng Yi-xian Cao Kun Zhao Clinical Medical College of Jining Medical University Jining Medical UniversityJining 272000Shandong ProvinceChina Department of Gastroenterology The First People's Hospital of JiningJining 272000Shandong ProvinceChina

BACKGROUND Schwannomas are uncommon tumors originating from Schwann cells,forming the neural sheath.They account for approximately 2%-6%of all mesenchymal tumors and are most commonly identified in peripheral nerve trunks,with rarity in the gastrointestinal tract.Among gastrointestinal locations,the stomach harbors the majority of nerve sheath tumors,while such occurrences in the sigmoid colon are exceptionally infrequent.CASE SUMMARY This study presented a clinical case involving a 60-year-old female patient who,during colonoscopy,was diagnosed with a submucosal lesion that was later identified as a nerve sheath tumor.The patient underwent surgical resection,and the diagnosis was confirmed through immunohistochemistry.This study highlighted an exceptionally uncommon occurrence of a nerve sheath tumor in the sigmoid colon,which was effectively managed within our department.Additionally,a comprehensive review of relevant studies was conducted.CONCLUSION The preoperative diagnosis of nerve sheath tumors poses challenges,as the definitive diagnosis still relies on pathology and immunohistochemistry.Although categorized as benign,these tumors have the potential to demonstrate malignant behavior.Consequently,the optimal treatment approach entails the complete surgical excision of the tumor,ensuring the absence of residual lesions at the margins.

关键词： Schwannoma Gastrointestinal stromal tumors Treatment Sigmoid colon Case report

Influence of the Acoustic Liner in Large Eddy Simulation of Longitudinal Thermoacoustic Instability in a Model Annular Combustor

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Journal of Thermal Science 2024年第2期33卷 710-724页

作者： meng Sheng ZHANG Man gao Yi AECC Commercial Aircraft Engine Co. Ltd.Shanghai200241China School of Aeronautics and Astronautics Shanghai Jiao Tong UniversityShanghai200240China

Although extensive efforts have been made to dampen the thermoacoustic instability,successfully controlling the pressure oscillations in modern gas turbines or aeroengines remains challenging.The influence of the acoustic liner on the longitudinal thermoacoustic mode in a model annular combustor is investigated by Large Eddy Simulation(LES) in this work.The result of the self-excited longitudinal thermoacoustic instability without the liner agrees well with the frequency and acoustic analysis of the pressure mode based on experimental data.Three different bias flow velocities of the liner located downstream of the combustor are then simulated.The results reveal that the existence of the liner influences not only the acoustic field but also the flow field.When the bias velocity is large,it leads to intense turbulence-induced fluctuations,and the pressure oscillation is modulated intermittently.It shows that the weak coupling between flow and pressure oscillations plays a significant role in the onset of the intermittency of a thermoacoustic system.Based on the dynamic analysis of the thermoacoustic system with the acoustic liner,this intermittency is caused by the influence of the flow field on the flame-acoustic coupling.Finally,a low-order modeling method based on Van der Pol(VdP) oscillator with additive stochastic forcing is conducted to reproduce the evolving dynamics of the thermoacoustic system.Although the numerical cases demonstrated in this work are relatively simpler than those in a practical combustion system,the results are helpful for us to understand the effect of the acoustic liner and show the attractive potential to apply this device to suppress thermoacoustic instability.

关键词： thermoacoustic instability acoustic liner Large Eddy Simulation low-order modeling

DNA Damage-driven Inflammatory Cytokines:Reprogramming of Tumor Immune Microenvironment and Application of Oncotherapy

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Current Medical Science 2024年第2期44卷 261-272页

作者： meng-jie WANG Yu xiA Qing-lei gao Department of Obstetrics and Gynecology National Clinical Research Center for Obstetrics and GynecologyTongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430030China Key Laboratory of Cancer Invasion and Metastasis(Ministry of Education) Hubei Key Laboratory of Tumor Invasion and MetastasisTongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430030China

DNA damage occurs across tumorigenesis and tumor development.Tumor intrinsic DNA damage can not only increase the risk of mutations responsible for tumor generation but also initiate a cellular stress response to orchestrate the tumor immune microenvironment(TIME)and dominate tumor progression.Accumulating evidence documents that multiple signaling pathways,including cyclic GMP-AMP synthase-stimulator of interferon genes(cGAS-STING)and ataxia telangiectasia-mutated protein/ataxia telangiectasia and Rad3-related protein(ATM/ATR),are activated downstream of DNA damage and they are associated with the secretion of diverse cytokines.These cytokines possess multifaced functions in the anti-tumor immune response.Thus,it is necessary to deeply interpret the complex TIME reshaped by damaged DNA and tumor-derived cytokines,critical for the development of effective tumor therapies.This manuscript comprehensively reviews the relationship between the DNA damage response and related cytokines in tumors and depicts the dual immunoregulatory roles of these cytokines.We also summarize clinical trials targeting signaling pathways and cytokines associated with DNA damage and provide future perspectives on emerging technologies.

关键词： DNA damage tumor immune microenvironment inflammatory cytokines cancer therapy

Photocatalytic Activity Enhancement in Organic Dyes Degradation by Loading Ag Nanoparticles onto α-Fe_(2)O_(3)/ZnOs

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Journal of Wuhan University of Technology(Materials Science) 2024年第2期39卷 309-314页

作者：李保六 meng xinrui YUE Yifan gao Fang Key laboratory of Hubei Province for Coal Conversion and New Carbon Materials Wuhan University of Science and TechnologyWuhan 430081China

Fe_(2)O_(3)/ZnO/Ag ternary composite photocatalytic material was prepared by simple hydrothermal method,and its structure and photocatalytic properties were studied.The experimental results show that Fe_(2)O_(3)/ZnO/Ag exhibits better photocatalytic performance.After two hours of UV irradiation,the degradation rates of orange Ⅱ and methyl orange reached 91.9% and 75.9%,respectively.The design and preparation of the photocatalyst provide a theoretical basis for the practical application of photocatalytic technology.

关键词： Fe_(2)O_(3) ZnO composites photocatalysis

Rational Design of Ruddlesden-Popper Perovskite Ferrites as Air Electrode for Highly Active and Durable Reversible Protonic Ceramic Cells

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Nano-Micro Letters 2024年第9期16卷 308-324页

作者： Na Yu Idris Temitope Bello xi Chen Tong Liu Zheng Li Yufei Song meng Ni Department of Building and Real Estate Research Institute for Sustainable Urban Development(RISUD)and Research Institute for Smart Energy(RISE)The Hong Kong Polytechnic UniversityHung HomKowloonHong KongPeople’s Republic of China The Hong Kong Polytechnic University Shenzhen Research Institute Shenzhen 518057GuangdongPeople’s Republic of China Department of Mechanical and Aerospace Engineering The Hong Kong University of Science and TechnologyClear Water BayHong KongPeople’s Republic of China

Reversible protonic ceramic cells(RePCCs)hold promise for efficient energy storage,but their practicality is hindered by a lack of high-performance air electrode materials.Ruddlesden-Popper perovskite Sr_(3)Fe_(2)O_(7−δ)(SF)exhibits superior proton uptake and rapid ionic conduction,boosting activity.However,excessive proton uptake during RePCC operation degrades SF’s crystal structure,impacting durability.This study introduces a novel A/B-sites co-substitution strategy for modifying air electrodes,incorporating Sr-deficiency and Nb-substitution to create Sr_(2.8)Fe_(1.8)Nb_(0.2)O_(7−δ)(D-SFN).Nb stabilizes SF’s crystal,curbing excessive phase formation,and Sr-deficiency boosts oxygen vacancy concentration,optimizing oxygen transport.The D-SFN electrode demonstrates outstanding activity and durability,achieving a peak power density of 596 mW cm^(−2)in fuel cell mode and a current density of−1.19 A cm^(−2)in electrolysis mode at 1.3 V,650℃,with excellent cycling durability.This approach holds the potential for advancing robust and efficient air electrodes in RePCCs for renewable energy storage.

关键词： Reversible protonic ceramic cells Air electrode Ruddlesden-Popper perovskite Hydration Oxygen reduction reaction