检索结果-南通市图书馆

Photoinduced toxicity single and binary mixtures of four polycyclic aromatic hydrocarbons to the marine diatom Skeletonema costatum

引用

Acta Oceanologica Sinica 2007年第6期26卷 41-50页

作者： meng wei wang Liping ZHENG Binghui River and Coastal Environment Research Center Chinese Research Academy of Environmental Sciences Beijing 100012 China

Diatom Skeletonema costatum Cleve is one of the main predominant phytoplankton species in the Changjiang Estuary in China. In order to provide some basic information for future assessment of the potential risk on phytoplankton communities in this estuary caused by polycyclic aromatic hydrocarbons（ PAHs）, this alga was selected as a representative to investigate the photoinduced toxicity of PAHs, in single and mixture. Four PAHs including three-ring phenanthrene and anthracene, four-ring fluoranthene and pyrene were tested in the laboratory. The single toxicity of each PAH on this microalga was compared with and without the simulated solar UV radiation. The results showed that this microalga was sensitive to PAH＇ s photoinduced toxicity. Ratios of the 72 h median effect concentration obtained for fluorescent and UV light tests were about 8.4 for phenanthrene, 13.0 for anthracene, 6. 5 for fluoranthene, and 5.7 for pyrene, indicating that UV light enhanced the PAH toxicity to this alga significantly. Under the fluorescent radiation （lacking UV ）, the dose-response curves based on chemical concentrations revealed that the order of toxic strength was fluoranthene greater than pyrene greater than anthracene greater than phenanthrene; while under the UV radiation （476 μW/cm^2 for UVA, 6.5 μW/cm^2 for UVB） it became fluoranthene approximately equaling anthracene greater than pyrene greater than phenanthrene, indicating that the UV light also changed its relative toxicity to this alga. The photoinduced toxicity of PAHs to the marine diatom S. costatum might be a synergistic effect of photosensitization reactions （ e. g. , generation of singlestate oxygen） and photomodification （photooxidation and/or photolysis）. The combined effects of six binary mixtures on the marine diatom S. costatum were investigated using the additive-index method. Four binary-mixtures （ phenanthrene plus anthracene ; phenanthrene plus pyrene ; anthracene plus fluoranthene ; anthracene plus pyrene） we

关键词： marine diatom polycyclic aromatic hydrocarbons phototoxicity combined toxicity

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effect of Ultrasonication on Optical Properties and Electronic States of Conjugated Polymer MEH-PPV

引用

Chemical Research in Chinese Universities 2008年第5期24卷 653-657页

作者： WU meng YANG Gui-zhong wang meng wang wei-zhi wang Min LIU Tian-xi Key Laboratory of Molecular Engineering of Polymers of Ministry of Education Department of Macromoleeular Science Laboratory of Advanced Materials Fudan University Shanghai 200433 P. R. China

Poly[2-methoxy-5-（2＇-ethyl-hexyloxy）-1,4-phenylene vinylene]（MEH-PPV）solutions with different concen-trations were prepared in chloroform for different ultrasonication *** ultraviolet absorption and photoluminescence（PL）spectra of the MEH-PPV solutions were measured,and the electronic states of the polymer chains under different experimental conditions were *** results showed that the effects of ultrasonication on the dilute and concentrated solutions were *** ultrasonication,the intensity of the absorption peak at 280 nm significantly decreased,relative to the absorption peak at 500 nm for both dilute and concentrated solutions,indicating that the proportion of the two excited states in the polymer chains had *** dilute MEH-PPV solutions,the blue-shifted absorption（at about 500 nm）and PL spectra show that ultrasonication also led to polymer chain degradation and thus shortened the effective conjugation *** concentrated solutions,however,the peak positions of the absorption spectra remained *** addition,the effects of the solution temperatures on the optical spectra for the MEH-PPV solutions were also discussed.

关键词： MEH-PPV Optical property Electronic state Ultrasonication

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

LINE-1 family member GCRG123 gene is up-regulated in human gastric signet-ring cell carcinoma

引用

World Journal of Gastroenterology 2008年第5期14卷 758-763页

作者： Gang-Shi wang meng-wei wang Ben-Yan Wu Xin-Yan Yang wei-Hua wang wei-Di You Department of Gerontal Gastroenterology General Hospital of Chinese PLA Beijing 100853 China

AIM： To analyze the expression profiles of a human gastriccancer-related gene, GCRG123, in human gastric signetring cell carcinoma tissues, and to perform bioinformatics analysis on GCRG123.METHODS： In situ hybridization was used to explore the GCRG123 expression pattern in paraffin-embedded gastric tissues, including 15 cases of signet-ring cell carcinoma, 15 of intestinal-type adenocarcinoma, and 15 of normal gastric mucosa. Northern blotting was used to analyze the differences in GCRG123 expression between stomach signet-ring cell carcinoma and intestinal-type adenocarcinoma tissues. Online software, including BLAST, Multalin and BLAT, were applied for bioinformatics analysis. National Center for Biotechnology Information （NCBI） and the University of California Santa Cruz （UCSC） databases were used for the analyses.RESULTS： The in situ hybridization signal appeared as blue precipitates restricted to the cytoplasm. Ten out of 15 cases of gastric signet ring cell carcinoma, normal gastric mucosal epithelium and pyloric glands showed high GCRG123 expression. Low GCRG123 expression was observed in gastric intestinal-type adenocarcinoma and normal gastric glands. Northern blotting revealed that GCRG123 was up-regulated in signet-ring cell carcinoma tissue but down-regulated in intestinal-type adenocarcinoma tissue. BLAST and Multalin analyses revealed that the GCRG123 sequence had 92% similarity with the ORF2 sequence of human long interspersed nuclear element retrotransposons （LINE-1, L1）. BLAT analysis indicated that GCRG123 mapped to all chromosomes. GCRG123 was found to integrate in the intron-17 and -23 of Rb, 5＇ flanking region of IL-2 and clotting factor Ⅸ genes.CONCLUSION： GCRG123, an active member of the Lt family, was up-regulated in human gastric signet-ring cell carcinoma.

关键词： Stomach Signet-ring cell carcinoma GCRG123 LINE-1 In situ hybridization Bioinformatics

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Early hemodynamics after tibial transverse transport in patients with nonarterial stenosis and arterial stenosis diabetic foot

引用

World Journal of Diabetes 2023年第12期14卷 1784-1792页

作者： Mei-Mei Liao Sen Chen Jia-Rui Cao meng-wei wang Zhi-Hui Jin Jia Ye Yi-Jun Ren Rui-Qiang Guo Department of Ultrasound Imaging Renmin Hospital of Wuhan UniversityWuhan 430060Hubei ProvinceChina Department of Orthopedics Renmin Hospital of Wuhan UniversityWuhan 430060Hubei ProvinceChina

BACKGROUND The diagnosis of peripheral arteriopathy in the diabetic foot is complicated by diabetes and its advanced *** has been found that diabetic foot can be categorized into arterial stenosis and non-arterial stenosis,both of which have significant differences in hemodynamic *** To evaluate the early hemodynamic changes in diabetic foot patients with nonarterial stenosis and arterial stenosis treated by tibial transverse transport(TTT)using high-frequency color Doppler ultrasonography(HFCDU)and a laser Doppler *** Twenty-five patients with Wagner grades 3-5 diabetic foot ulcers were treated with TTT,and the wound healing time and rate were *** were grouped according to the results of preoperative lower-extremity *** with≥50%stenosis in any of the femoral,popliteal,posterior tibial,anterior tibial,and peroneal arteries of the affected limb were classified as the arterial stenosis group(n=16);otherwise,they were classified as the nonarterial stenosis group(n=9).Before and one month after surgery,HFCDU was used to evaluate the degree of lower limb artery lesions and hemodynamic changes in *** degree of femoral-popliteal atherosclerotic stenosis,the degree of vascular stenosis and occlusion of the lower-knee outflow tract,and the degree of medial arterial calcification were scored;the three scores were added together to obtain the total score of lower extremity ***3,a laser Doppler flowmeter system,was used to detect alterations in plantar microcirculation before and 1 mo after *** healing and hemodynamic indices were compared between the two *** The wound healing time of the diabetic foot was significantly shorter in the nonarterial stenosis group than in the arterial stenosis group(47.8±13 vs 85.8±26,P<0.05),and the wound healing rate of both groups was 100%.The preoperative total lower extremity arteriopathy scores were lower in the nonar

关键词： High-frequency color Doppler ultrasonography Diabetic foot Tibial transverse transport Nonarterial stenosis Arterial stenosis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A novel gene,GCRG224,is differentially expressed in human gastric mucosa

引用

World Journal of Gastroenterology 2003年第1期9卷 30-34页

作者： Gang-Shi wang meng-wei wang Ben-Yan Wu wei-Di You Xin-Yan Yang Department of Gastroenterology,General Hospital of Chinese PLA,Beijing 100853,China Department of Gastroenterology General Hospital of Chinese PLA Beijing 100853 China. wanggangshi@***

AIM: To clone genes that may predispose us to humangastric cancer and to analyze it's expression in gastric ***: Specimens of paired tumor, paratumor andnormal gastric mucosa tissues collected from fifteen patientswho suffered from stomach antrum adenocarcinoma wereused for analysis. Seven out of the fifteen cases were firststudied by fluorescent differential display reversetranscription polymerase chain reaction (DDTR-PCR) *** differentially expressed bands of interest were cloned,analyzed by Northern blot, sequencing and RT-PCR. ThroughBLAST, the sequencing results were compared with GenBankdatabase for homology analysis. In situ hybridization withDIG-labeled cRNA probes was used to analyze the expressionof interesting cDNA bands in paraffin embedded pairednormal gastric mucosa and cancer tissues isolated from 30gastric adenocarcinoma ***: DDRT-PCR showed that one of the interestingcDNA bands, which was named W2, expressed much higherin all seven tested tumor and paratumor samples than intheir normal counterparts, it was sub-cloned into a pGEM-TEasy vector. Two subclones were subsequently *** of the subclone, GCRG224, was studied further. Thesequencing result showed that GCRG224 consisted of 1 159base pairs and had one open reading frame (ORF). It locatedat human chromosome 11q14. No homologue was found inGenBank database with GCRG224-ORF. This nucleotidesequence data were submitted to GenBank with accessionNo. AF438406. RT-PCR showed that GCRG224 expressedhigher in 11/15 gastric cancer tissues than in non-tumortissues. However, the result of Northern blot analysis showeda higher GCRG224 expression in the non-tumor tissue thanin the tumor one. Human multiple tissue Northern blot analysisrevealed that GCRG224 also expressed in human normal colontissue, and peripheral blood leukocyte. In situ hybridizationanalysis showed that only 5/30 adenocarcinoma, 3/18dysplasia and 6/18 intestinal metaplasia showed higherGCRG224 express

关键词： GCRG224基因胃癌胃粘膜聚合酶链反应克隆肿瘤病理学

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hematoma enlargement-related factors in hypertensive cerebral hemorrhage

引用

Neural Regeneration Research 2008年第8期3卷 925-928页

作者： Dengji Pan Zhouping Tang Feng Xu Di Chen Xingyong Chen Xiangwu meng Suiqiang Zhu wei wang Department of Neurology Tongji Hospital of Tongji Medical College Huazhong University of Science and Technology Wuhan 430030 Hubei Province. China

BACKGROUND：Continuous hemorrhage or hematoma enlargement often occurs following cerebral hemorrhage attacks. OBJECTIVE： To retrospectively analyze the influential factors for hematoma enlargement in patients with hypertensive cerebral hemorrhage prior to minimally invasive surgery. DESIGN, TIME AND SETTING： A comparative analysis of 90 patients with cerebral hemorrhage undergoing minimally invasive surgery at the Department of Neurology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology between April 2005 and February 2007. PARTICIPANTS： Fifty-eight males and thirty-one females aged （52.7 ± 5.23） years （range, 28-73 years）. METHODS： Cranial CT was performed twice to objectively identify hematoma enlargement. Patients with hematoma enlargement prior to surgery were selected as the observation group （n = 30）, and those with no obvious hematoma changes served as the control group （n = 60）. Following cranial CT localization, the two groups underwent minimally invasive hematoma aspiration and drainage, according to Standardized Treatment Guidelines for Micro-invasive Aspiration and Drainage of Intracranial Hematoma. MAIN OUTCOME MEASURES： Hemorrhage site, coagulation function, diabetes history, and clinical symptoms. RESULTS： There were no significant differences in hemorrhage sites between the two groups （χ2 = 2.262, P 〉 0.05）. The percent of intemperance patients in the observation group was significantly larger than the control group （χ2 = 6.923, P 〈 0.01）. No significant differences in terms of percent of coagulation dysfunction or diabetes were determined between the two groups （χ2 = 0.03, 0.08, P 〉 0.05）. The percent of patients with clinical deterioration was significantly higher in the observation group, compared to the control group （χ2 = 25.57, P 〈 0.01）. CONCLUSION： Intemperance and preoperative clinical deterioration may increase incidence of hematoma enlargement prior to minimally invasive surgery in patients with hyper

关键词： cerebral hemorrhage hematoma enlargement intemperance

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

CysLT1 receptor antagonist praniukast protects mice from traumatic brain cryoinjury

引用

中国药理通讯 2005年第4期22卷 33-34页

作者： Xiao - Dong Qian Lei Zhang meng - Ling wang wei - Ping Zhang Er- Qing wei Department of Pharmacology School of Medicine Zhejiang University Hangzhou 310031

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Small modifications of endo-functionalized cavities lead to large changes in molecular interaction in water

引用

Science China Chemistry 2025年第1期 369-376页

作者： Song-meng wang Hao Nian Yan-Fang wang Li-Shuo Zheng Yu-Tao Zheng Yi-wei Dong Liping Huang Xiaoping wang wei Jiang Liu-Pan Yang Department of Chemistry Southern University of Science and Technology School of Chemistry and Pharmaceutical Sciences State Key Laboratory for Chemistry and Molecular Engineering of Medicinal ResourcesGuangxi Normal University School of Pharmaceutical Science Hengyang Medical School University of South China

Studying molecular recognition in aqueous environments is crucial for understanding biological processes. Herein, we present a series of N-doped endo-functionalized anthracene-based cavities by introducing inward-directed pyridine units. The subtle modifications can significantly affect the binding properties of these receptors, which is similar to the mutations in biological systems. Combining theoretical calculations and molecular recognition experiments demonstrated that these “mutations” have an impact on the hydrophobicity and charge distribution of the hosts, consequently significantly influencing molecular *** is crucial for understanding the intricate mechanisms of molecular-level interactions in biological receptors.

关键词：

来源：

同方期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Joint Probabilistic Scheduling and Resource Allocation for Wireless Networked Control Systems

引用

IEEE/CAA Journal of Automatica Sinica 2025年第1期 258-260页

作者： meng Zheng Lei Zhang wei Liang IEEE the State Key Laboratory of Robotics and the Key Laboratory of Networked Control Systems Shenyang Institute of Automation Chinese Academy of Sciences the University of Chinese Academy of Sciences

Dear Editor,This letter presents a joint probabilistic scheduling and resource allocation method(PSRA) for 5G-based wireless networked control systems(WNCSs). As a control-aware optimization method, PSRA minimizes the linear quadratic Gaussian(LQG) control cost of WNCSs by optimizing the activation probability of subsystems, the number of uplink repetitions, and the durations of uplink and downlink phases. Simulation results show that PSRA achieves smaller LQG control costs than existing works.

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

中国老年人失能轨迹的性别、城乡及队列差异

引用

人口与发展 2017年第5期23卷 74-81,98页

作者：魏蒙王红漫北京大学医学人文研究院北京100191

采用2005、2008、2011年的《中国老年健康影响因素跟踪调查》项目,运用组基轨迹模型考察了存活、死亡、失访老年人的失能轨迹以及总体老年人的失能轨迹的性别、城乡、队列差异。存活、死亡、失访老人的失能轨迹存在明显的差异,死亡老人... 详细信息

采用2005、2008、2011年的《中国老年健康影响因素跟踪调查》项目,运用组基轨迹模型考察了存活、死亡、失访老年人的失能轨迹以及总体老年人的失能轨迹的性别、城乡、队列差异。存活、死亡、失访老人的失能轨迹存在明显的差异,死亡老人起点更高、发展更迅速;女性老人、城市老人更倾向于走上自理能力不健全的轨迹;越来越多的老年人的自理状况是完善的,但失能的老年人其自理状况较之前恶化。

关键词：性别城乡队列失能轨迹组基轨迹模型

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：