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Human immunodeficiency virus-associated dementia complex with positive 14-3-3 protein in cerebrospinal fluid:A case report

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World Journal of Clinical Cases 2024年第12期12卷 2065-2073页

作者： Yun-Sen He Xiao-Hong Qin Min Feng Qin-Jiang Huang meng-jun zhang Li-Li Guo Ming-Bin Bao Ye Tao Hong-Yuan Dai Bo Wu Department of Neurosurgery Sichuan Lansheng Brain Hospital&Shanghai Lansheng Brain Hospital Investment Co.Ltd.Chengdu 610036Sichuan ProvinceChina Department of Psychiatry Sichuan Provincial Center for Mental HealthChengdu 610072Sichuan ProvinceChina Department of Geriatrics Municipal People’s Hospital in LuzhouLuzhou 646000Sichuan ProvinceChina Department of Neurosurgery Wenjiang District People’s Hospital of ChengduChengdu 611100Sichuan ProvinceChina Department of Neurosurgery Sichuan Provincial People's HospitalUniversity of Electronic Science and Technology of China ChengduChengdu 610072Sichuan ProvinceChina Department of Neurology Sichuan Provincial People’s HospitalUniversity of Electronic Science and Technology of ChinaChengdu 610072Sichuan ProvinceChina

BACKGROUND Human immunodeficiency virus(HIV)-associated dementia(HAD)is a subcortical form of dementia characterized by memory deficits and psychomotor ***,HAD often presents with symptoms similar to those of Creutzfeldt-Jakob disease(CJD),particularly in patients with acquired immune deficiency syndrome(AIDS).CASE SUMMARY We report the case of a 54-year-old male who exhibited cognitive dysfunction and secondary behavioral changes following HIV infection and suspected prion *** patient was diagnosed with HIV during hospitalization and his cerebrospinal fluid tested positive for 14-3-3 *** electroencephalogram showed a borderline-abnormal periodic triphasic wave ***-enhanced magnetic resonance imaging revealed moderate encephalatrophy and ***,symptomatic treatment and administration of amantadine were pursued for presumed CJD,but the patient’s condition continued to *** contrast,the patient’s condition improved following anti-HIV *** individual is also the only patient with this prognosis to have survived over 4 ***,the diagnosis was revised to *** In the diagnostic process of rapidly progressive dementia,it is crucial to rule out as many potential causes as possible and to consider an autopsy to diminish diagnostic *** 14-3-3 protein should not be regarded as the definitive marker for *** laboratory screening for infectious diseases is essential to enhance diagnostic precision,especially in AIDS patients with potential ***,a trial of diagnostic treatment may be considered when additional testing is not feasible.

关键词： HIV-associated dementia Cognitive dysfunction Creutzfeld-Jakob disease Rapidly progressive dementia Case report

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Output Feedback Stabilization of High-Order Nonlinear Time-Delay Systems With Low-Order and High-Order Nonlinearities

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IEEE/CAA Journal of Automatica Sinica 2024年第5期11卷 1304-1306页

作者： meng-meng Jiang Kemei zhang Xue-jun Xie School of Mathematics Science Liaocheng UniversityLiaocheng 252059China School of Mathematics Science Qufu Normal UniversityQufu 273165China Institute of Automation Qufu Normal UniversityQufu 273165China

Dear Editor,to This letter deals with the output feedback stabilization of a class of high-order nonlinear time-delay systems with more general low-order and high-order *** constructing reduced-order observer,based on homogeneous domination theory together with the adding a power integrator method,an output feedback controller is developed guarantee the equilibrium of the closed system globally uniformly asymptotically stable.

关键词： Nonlinear stabilization guarantee

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On-Chip Sub-Picometer Continuous Wavelength Fiber-Bragg-Grating Interrogator

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Photonic Sensors 2024年第1期14卷 73-84页

作者： Yuan ZHUANG jun ZOU Jiqiang zhang Lu zhang Jiahe zhang Leixin meng Qing YANG Research Center for Humanoid Sensing Zhejiang LabHangzhou 311121China ZJU-Hangzhou Global Scientific and Technological Innovation Center Hangzhou 310014China State Key Laboratory of Modern Optical Instrumentation College of Optical Science and EngineeringInternational Research Center for Advanced PhotonicsZhejiang UniversityHangzhou 310058China

Miniaturized fiber-Bragg-grating(FBG)interrogators are of interest for applications in the areas where weight and size controlling is important,e.g.,airplanes and aerospace or in-situ *** ultra-compact high-precision on-chip interrogator is proposed based on a tailored arrayed waveguide grating(AWG)on a silicon-on-insulator(SOI)*** on-chip interrogator enables continuous wavelength interrogation from 1544 nm to 1568 nm with the wavelength accuracy of less than 1 pm[the root-mean-square error(RMSE)is 0.73 pm]over the whole wavelength *** chip loss is less than 5 *** 1×16 AWG is optimized to achieve a large bandwidth and a low noise level at each channel,and the FBG reflection peaks can be detected by multiple output channels of the *** fabricated AWG is utilized to interrogate FBG sensors through the center of gravity(CoG)*** validation of an on-chip FBG interrogator that works with sub-picometer wavelength accuracy in a broad wavelength range shows large potential for applications in miniaturized fiber optic sensing systems.

关键词： Fiber optic sensing on-chip interrogator arrayed waveguide grating center of gravity

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The Effect of Blending Ratio on the Structure and Properties of the PPR/PS In situ Fiber Reinforced System Prepared by Multi-Flow Vibration Injection Molding

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Chinese Journal of Polymer Science 2024年第6期42卷 851-863页

作者： Yan-Jiang Li meng-Long Hu jun-Wen zhang Qiang Fu Jie zhang College of Polymer Science and Engineering State Key Laboratory of Polymer Materials EngineeringSichuan UniversityChengdu610065China

To enhance the mechanical properties of polypropylene random copolymer(PPR),polystyrene(PS)with four different contents were added to the PPR matrix through melt ***,using the Multi-Flow Vibration Injection Molding(MFVIM)technology,PPR/PS in situ microfiber composites(MFC)with different blending ratios were *** results indicated that blending ratio had a great impact on the phase morphology and crystal structure of MFVIM samples,which was different from those of conventional injection molding(CIM)*** ultrafine fibers could be formed under the shear field and could absorb the PPR molecular chains to form hybrid shish-kebab ***,the PPR matrix could also form shish-kebab structures under the effect of strong *** the PS content reached 20%,under the combined action of PS in situ microfibers and highly oriented crystal structure,the tensile strength and Young’s modulus of the sample were obviously improved and the impact strength remained at a relatively high *** a strong and tough balanced PPR based material was *** results provide valuable insights for expanding the industrial and daily-life applications of PPR and show promising development prospects.

关键词： PPR MFVIM In situ microfibers Shearfield Hybrid shish-kebab structures

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An analysis of TinyML@ICCAD for implementing AI on low-power microprocessor

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Science China(Information Sciences) 2024年第4期67卷 343-344页

作者： Guoqing LI Jingwei zhang meng zhang Tuo LI Tinghuan CHEN jun YANG Shandong Yunhai Guochuang Cloud Computing Equipment Industry Innovation Co. Ltd. School of Integrated Circuits Southeast University Shandong Inspur Artificial Intelligence Research Institute Co. Ltd. School of Science and Engineering The Chinese University of Hong Kong

Tiny machine learning(ML) is an important application area of artificial intelligence(AI), which focuses on deploying AI on small hardware platforms with constrained resources [1, 2]. The high-level TinyML contests at high-level conferences promote the development of TinyML areas, such as DAC-SDC [3] and TinyML@ICCAD [4].

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Highly Red Emissive Conjugated Homopolymers Based on Double B←N Bridged Bipyridine Unit

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CHINESE JOURNAL OF POLYMER SCIENCE 2024年第8期42卷 1029-1037页

作者： Gao, Yu-Yue zhang, Kai-Yuan Wang, Shu-meng Tong, Hui Liu, jun Chinese Acad Sci Changchun Inst Appl Chem State Key Lab Polymer Phys & Chem Changchun 130022 Peoples R China Univ Sci & Technol China Sch Appl Chem & Engn Hefei 230026 Peoples R China

Conjugated homopolymers based on six-member rings, e.g., polyfluorene, always exhibit blue emission and conjugated homopolymers based on five-member rings, e.g., polythiophene, can give red emission with low efficiency. In this work, we report a series of new conjugated homopolymers based on six-member rings with high-efficiency deep-red emission. The repeating units of the red light emitting homopolymers are double B <- N bridged bipyridine (BNBP) with the boron atoms functionalized with diphenyl, borafluorene, and 2,7-di-tert-butyl-borafluorene groups, respectively. The relationship between the chemical structures and the opto-electronic properties of the monomers and the homopolymers has been systematically studied. The three polymers emit pure red light (lambda max=656 nm) or deep red light (lambda max=693 nm) with fluorescence quantum efficiency in solution higher than 60%. The polymers can be used as the emitters in solution-processed organic light-emitting diodes with red emission and decent device performance. This work indicates a new strategy to design highly efficient light emitting conjugated polymers.

关键词： Conjugated homopolymers Double B <- N bridged bipyridine (BNBP) Deep-red emission High fluorescent efficiency LIGHT-EMITTING-DIODES NEAR-INFRARED EMISSION POLYMER ELECTROLUMINESCENCE POLYFLUORENES PHOTOPHYSICS DISPLAYS ACCEPTOR

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Dielectric and energy storage properties of PbO–SrO–Nb_(2)O_(5)–Na_(2)O–Si thin films by annealing

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Rare Metals 2024年第1期43卷 351-355页

作者： Fei-Hu Tan Qing-meng zhang Feng Wei Hong-Bin Zhao Xiao zhang jun Du State Key Laboratory of Advanced Materials for Smart Sensing General Research Institute for Nonferrous MetalsBeijing 100088China Advanced Electronic Materials Institute General Research Institute for Nonferrous MetalsBeijing 100088China

Dielectric and energy storage properties of PbOSrO-Na_(2)O-Nb_(2)O_(5)-SiO_(2)(PSNNS) thin films with annealing temperature from 700 to 850 ℃ were investigated by measuring their capacitance-electric filed curve and hysteresis *** results show that the highest dielectric constant and energy density are 81.2 and 17.0 J·cm^(-3),respectively,which is obtained in the sample with annealing temperature of 800 ℃.Annealed from 700 to800 ℃,the dielectric constant and energy storage performance of PSNNS films are continuously ***,with annealing temperature up to 850 ℃,their dielectric constant decreases,which might be related with the removal of interfacial defects as a function of annealing *** is one of the causes of space charge phenomenon,resulting in the increase in dielectric ***,the micro structure analysis by X-ray diffraction(XRD) and transmission electron microscope(TEM) indicates that the change of crystallization phase and interfacial polarization takes responsibility to the results.

关键词： Thin film Pulse laser deposition Annealing temperature Energy storage density

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Recovery and in-situ reduction of precious metals by graphdiyne and graphdiyne oxide for antibacterial use

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Rare Metals 2024年第4期43卷 1747-1757页

作者： Ming-Ji Jiang Ya-Na zhang Ling-Shen meng Jing Kang Yong-jun Li Alideertu Dong College of Chemistry and Chemical Engineering Inner Mongolia UniversityHohhot010021China Engineering Research Center of Dairy Quality and Safety Control Technology Ministry of EducationInner Mongolia UniversityHohhot010021China Department of Chemistry University of ZurichCH-8057ZurichSwitzerland Laboratory of Organic Solids and Beijing National Laboratory for Molecular Sciences Institute of ChemistryChinese Academy of SciencesBeijing100190China

Based on the in-situ self-reduction and chemical stability,graphdiyne(GDY)and graphdiyne oxide(GDYO)are used as trapping agents to investigate the ability for recovering Au^(3+),Ag^+,and Pd^(2+)under different pH values and interfering *** strong acidity at pH=1,these two agents demonstrate high select recovery towards the three precious metal ions,which could be insitu reduced to nanoparticles(NPs).In addition,superparamagnetic Fe_(3)O_(4)NPs are deposited on the surfaces of GDY and *** magnetic responses enable GDYFe_(3)O_(4)to recover precious metals conveniently and efficiently by the aid of an external magnetic *** study also confirms the antibacterial activity of the as-recovered NPs deposited on GDY and GDYO against Escherichia coli and Staphylococcus aureus(1×10^(5)colony-forming unit(CFU)·mL^(-1)),and the antibacterial rates are 100%.This strategy of recovering precious metals and subsequently reusing to combat pathogens will be of great significance for environmental remediation and biomedical applications.

关键词： Graphdiyne In-situ reduction Recovery Precious metals Antibacterial

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Research progress of slippage characteristic and gas film stability enhancement methods on biomimetic hydrophobic surfaces

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Journal of Hydrodynamics 2024年第1期36卷 87-101页

作者： meng-zhuo zhang Hai-bao Hu Liu-zhen Ren Lu-yao Bao jun Wen Luo Xie School of Marine Science and Technology Northwestern Polytechnical UniversityXi’an710072China Research and Development Institute of Northwestern Polytechnical University in Shenzhen Shenzhen518063China

The biomimetic hydrophobic surface is a potentially efficient underwater drag reduction method and the drag reduction mechanism of this kind of surface comes from the interfacial *** now,it is a hotspot to grasp the slippage characteristic and explore slippage enhancement *** paper not only summarizes our numerical simulation and experimental results of slippage characteristic at the solid-liquid interface(SLI)of hydrophobic surfaces(HS)and the gas-liquid interface(GLI)of superhydrophobic surfaces(SHS)in recent years,but also introduces some innovative methods that can effectively improve the gas film stability and drag reduction effect of ***,we used the molecular dynamics(MD)simulation method to figure out the effect of the solid-liquid interaction strength,the system temperature and the shear rate on the slippage of SLI,and expound their action mechanism from molecular ***,by MD and multibody dissipative particle dynamics(MDPD)method,the slippage behavior at the GLI was studied under the influence of the microstructure size and the flow driving *** proposed a new kind of hybrid slip boundary condition model to describe the slippage characteristic on *** addition,we found through experiment that a three-dimensional backflow will appear on the GLI under the interfacial adsorption of surfactants,and the backflow direction will reverse with the change of GLI ***,we put forward the wettability step structure and gas injection method to enhance the stability and drag reduction effect of the gas film on SHS.

关键词： Hydrophobic surface superhydrophobic surface interfacial slip underwater drag reduction

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The reservoir characteristics and their controlling factors of the sublacustrine fan in the Paleogene Dongying Formation, Bohai Sea,China

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Journal of Palaeogeography 2024年第1期13卷 127-148页

作者： Xiao-jun Pang Guan-Min Wang meng Zhao Qing-Bin Wang Xue-Fang zhang School of Geosciences China University of Petroleum(East China)QingdaoShandong 266580China Tianjin Branch of China National Offshore Oil Corporation Limited Tianjin 300459China

Sublacustrine fan is an important element in continental lacustrine basins and is significant for reservoir exploration. Oil and gas resources have been found in the sublacustrine fan sandstone reservoirs of the Paleogene Dongying Formation in the Bohai Sea. In this study, the characteristics of the sublacustrine fan reservoirs and the controlling factors are studied using information from logging, cores, physical properties,casting thin sections, X-ray diffraction of clay minerals, vitrinite reflectance, rock pyrolysis, manometry data,and 3D seismic data. The sublacustrine fans of the Dongying Formation in the LD10, QHD34, and BZ21 structures show high-quality reservoirs with porosity >15 % and permeability >5 m D. The main controlling factors of the high-quality reservoirs are attributed to the favorable sedimentary facies type and negligible compaction,and cementation, substantial dissolution of K-feldspar, overpressure, and the development of faults and fractures. A high-quality sublacustrine fan reservoir model has been established to explain how these factors affected the physical properties. The favorable targets for oil and gas exploration in the Dongying Formation of Bohai Sea include undercompacted sandy debris flow reservoirs showing the dissolution of K-feldspar, and the reservoirs which are connected to the source rocks by faults. This study provides insights to establish the relationship between sedimentology, diagenesis and reservoir quality. The results of this study are significant for the exploration and development of the sublacustrine fan sandstone reservoirs in the Bohai Sea and analogous sandstone reservoirs elsewhere.

关键词： Sublacustrine fan High-quality reservoir Dissolution Overpressure Fault Bohai Sea

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