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Irreversible demagnetization mechanism of permanent magnets during electromagnetic buffering

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Defence Technology（防务技术） 2021年第3期17卷 763-774页

作者： Zi-xuan Li Guo-lai Yang yu-meng Fan Jia-hao Li School of Mechanical Engineering Nanjing University of Science and TechnologyNanjingPR China

The permanent magnets will be irreversibly demagnetized under high temperature and high velocity during the electromagnetic *** this study,the magnetic field induced by eddy currents and the self-demagnetizing field of permanent magnet are taken into consideration together for demagnetization *** magnetic Reynolds number is used to express the eddy currents *** correction coefficient being expressed as the index of the air-gap width,the inner cylinder thickness,iron pole axial length and the permanent magnet demagnetization coefficient is introduced by magnetic path analysis to represent the self-demagnetization effect and the demagnetization *** electromagnetic buffer(EMB)prototype is tested under intensive impact loads of different strengths at room *** accuracy of the nonlinear irreversible demagnetization finite element model is verified by demagnetization on damping force,velocity and ***,high-velocity demagnetization and high-temperature demagnetization are analysed in order to obtain the distribution law of irreversible demagnetization.

关键词： EMB Irreversibly demagnetization Magnetic Reynolds number Correction coefficient

Vacancy-modified bimetallic FeMoS_(x)/CoNiP_(x) heterostructure array for efficient seawater splitting and Zn-air battery

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Journal of Energy Chemistry 2023年第6期81卷 533-542,I0012页

作者： Ansheng Wang Shan Gao Jiaguo Yan Chunning Zhao meng yu Weichao Wang Integrated Circuits and Smart System Lab(Shenzhen) Renewable Energy Conversion and Storage CenterTianjin Key Laboratory of Photo-Electronic Thin Film Device and TechnologyCollege of Electronic Information and Optical EngineeringNankai UniversityTianjin 300071China Department of Physical Science and Technology Ningbo UniversityNingbo 315211ZhejiangChina Division of Oilfield Chemicals China Oilfield Services LimitedTianjin 300452China

The development of highly efficient OER catalysts with superior durability for seawater electrolysis and Zn-air battery is important but ***,the vacancy-modified heterostructured bimetallic Fe Mo S_(x)/Co Ni P_(x)OER electrocatalyst is *** from the electron redistribution and reaction kinetics modulation resulting from vacancy introduction and heterojunction formation,it yields ultralow OER overpotentials of 196,276,303 m V in 1 M KOH and 197,318,348 m V in 1 M KOH+seawater at 10,500,1000 m A cm^(-2),respectively,surviving 600 h at 800 m A cm^(-2)without obvious ***,FeMoS_(x)/CoNiP_(x)-based Zn-air battery not only affords the high peak power density of 214.5 m W cm^(-2)but also exhibits the small voltage gap of 0.698 V and long lifetime of 500 h at 10 m A cm^(-2),overmatching overwhelming majority of reported advanced *** is revealed experimentally that the OER process on rationally designed Fe Mo S_(x)/Co Ni P_(x)follows the adsorbate evolution mechanism and the ratedetermining step shifts from^(*)OOH formation in individual building blocks to^(*)OOH deprotonation process in FeMoS_(x)/CoNiP_(x),providing the directly proof of how the vacancy introduction and heterojunction formation affect the reaction kinetics.

关键词： Vacancy Heterojunction Oxygen evolution reaction Seawater splitting Zn-air battery

Whole-Brain Map of Long-Range Monosynaptic Inputs to Different Cell Types in the Amygdala of the Mouse

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Neuroscience Bulletin 2020年第11期36卷 1381-1394页

作者： Jia-yu Fu Xiao-Dan yu Yi Zhu Shi-Ze Xie meng-yu Tang Bin yu Xiao-Ming Li Center for Neuroscience and Department of Neurology of Second Affiliated Hospital Zhejiang University School of MedicineHangzhou 310058China NHC and CAMS Key Laboratory of Medical Neurobiology Center for Brain Science and Brain-Inspired IntelligenceGuangdong-Hong Kong-Macao Greater Bay AreaJoint Institute for Genetics and Genome Medicine between Zhejiang University and University of TorontoHangzhou 310058China

The amygdala,which is involved in various behaviors and emotions,is reported to connect with the whole ***,the long-range inputs of distinct cell types have not yet been ***,we used a retrograde trans-synaptic rabies virus to generate a whole-brain map of inputs to the main cell types in the mouse *** identified 37 individual regions that projected to neurons expressing vesicular glutamate transporter 2,78 regions to parvalbumin-expressing neurons,104 regions to neurons expressing protein kinase C-δ,and 89 regions to somatostatin-expressing *** amygdala received massive projections from the isocortex and *** nuclei,such as the caudate-putamen and the CA1 field of the hippocampus,exhibited input preferences to different cell types in the ***,we identified several novel input areas,including the substantia innominata and zona *** findings provide anatomical evidence to help understand the precise connections and diverse functions of the amygdala.

关键词： Basolateral amygdala Central amygdala Rabies virus retrograde tracing Glutamatergic GABAergic Mouse

不同剂量注射用泮托拉唑钠在犬体内药代动力学研究

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中国兽药杂志 2025年第1期59卷 29-35页

作者：李冰李晶齐芸韩梦禹烟台赛普特检测服务有限公司山东烟台264003 山东爱士津生物技术有限公司山东烟台264003

为研究不同剂量的泮托拉唑钠在犬体内的药代动力学特征,建立LC-MS/MS法测定犬血浆中泮托拉唑钠浓度。血浆样品采用乙腈沉淀蛋白处理后,以双氯芬酸钠为内标,采用Waters ACQUITY BEH C_(18)(2.1 mm×50 mm,1.7μm)色谱柱进行分离,以乙腈-... 详细信息

为研究不同剂量的泮托拉唑钠在犬体内的药代动力学特征,建立LC-MS/MS法测定犬血浆中泮托拉唑钠浓度。血浆样品采用乙腈沉淀蛋白处理后,以双氯芬酸钠为内标,采用Waters ACQUITY BEH C_(18)(2.1 mm×50 mm,1.7μm)色谱柱进行分离,以乙腈-水(含0.1%的甲酸)为流动相进行梯度洗脱,在电喷雾正离子模式下,采用多反应监测模式进行定性与定量分析。应用此方法测定静脉注射给予低(2.00 mg/kg)、中(4.00 mg/kg)、高(8.00 mg/kg)三个剂量后犬体内泮托拉唑钠的血药浓度,并使用Phoenix WinNonlin软件计算主要的药动学参数。结果显示:泮托拉唑钠在15.0~15000 ng/mL浓度范围内呈现良好线性关系(R^(2)>0.999),定量下限为15.0 ng/mL;方法的批内与批间精密度(RSD)均小于15.0%,准确度RE%在9.00%以内;方法提取回收率在95.0%~101%范围内。比格犬静脉注射三个剂量组(2.00、4.00、8.00 mg/kg)后的主要药代参数如下:AUC_(0-t)分别为7714±2256、14389±5039、41149±9193 h·ng/mL;AUC_(0-∞)分别为7748±2248、14445±5042、41250±9232 h·ng/mL;C_(0)分别为8312±2460、16135±7401、37969±16618 ng/mL;t_(1/2)分别为0.638±0.0899、0.625±0.185、0.783±0.151 h,剂量变化对t_(1/2)、V无明显影响(P>0.05)。结果表明,建立的方法简单、高效、灵敏,静脉注射不同剂量后,注射用泮托拉唑钠在犬体内代谢较快,符合线性药代动力学特征。

关键词：泮托拉唑钠超高效液相色谱-串联质谱联用药动学线性关系分析

酿酒酵母发酵法制备桑黄多糖工艺优化及其结构表征和抗氧化活性研究

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天然产物研究与开发 2025年第1期37卷 85-94页

作者：逄梦玉隋昕怡刘丹刘养山任洪飞张景杜秀菊聊城大学生命科学学院聊城252000

为提高桑黄多糖提取得率和活性,优化发酵桑黄多糖(fermented Sanghuangporus sanghuang polysaccharide,SSP-F)的制备工艺,并对其进行结构表征及抗氧化活性评估。以临清桑黄为研究材料,以酿酒酵母为发酵菌种,以SSP-F的提取得率为响应值... 详细信息

为提高桑黄多糖提取得率和活性,优化发酵桑黄多糖(fermented Sanghuangporus sanghuang polysaccharide,SSP-F)的制备工艺,并对其进行结构表征及抗氧化活性评估。以临清桑黄为研究材料,以酿酒酵母为发酵菌种,以SSP-F的提取得率为响应值,基于单因素和响应面试验优化发酵工艺条件,采用高效阴离子交换色谱-脉冲安培检测法、傅里叶红外光谱、扫描电镜及X-衍射对其结构进行表征,并对其清除自由基的活性进行研究。结果表明:最佳工艺为发酵时间30.3 h、接种量9.3%、pH 7.0。在此条件下,SSP-F的提取得率为3.30%,比水提桑黄多糖(water extracted *** polysaccharide,SSP-W)的提取得率(2.34%)提高了41.03%。SSP-W和SSP-F均以吡喃环为基本骨架,由岩藻糖、氨基葡萄糖、葡萄糖和甘露糖组成,但其摩尔比有明显不同。此外,SSP-F的羟自由基清除率、还原力和ABTS+自由基清除率均高于SSP-W。本研究将为桑黄资源的合理开发和精深加工提供科学依据。

关键词：桑黄多糖酿酒酵母工艺优化结构表征抗氧化活性

综合性医院非结核分枝杆菌菌种分布及其耐药性

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中华医院感染学杂志 2025年第2期35卷 202-206页

作者：鲍容沈佳瑾陈裕缪青姚雨濛王蓓丽潘柏申郭玮胡必杰复旦大学附属中山医院检验科上海200032 复旦大学附属中山医院感染性疾病科上海200032 复旦大学附属中山医院感染管理科上海200032

目的了解综合性医院非结核分枝杆菌(NTM)感染患者临床分离NTM菌种类型,分析抗菌药物敏感性,为临床早期诊断和治疗提供依据。方法收集2023年1—12月就诊于复旦大学附属中山医院感染性疾病科NTM感染患者NTM临床分离株,通过基质辅助激光解... 详细信息

目的了解综合性医院非结核分枝杆菌(NTM)感染患者临床分离NTM菌种类型,分析抗菌药物敏感性,为临床早期诊断和治疗提供依据。方法收集2023年1—12月就诊于复旦大学附属中山医院感染性疾病科NTM感染患者NTM临床分离株,通过基质辅助激光解析/电离飞行时间质谱进行菌种鉴定,采用微量肉汤稀释法检测抗菌药物敏感性。结果共收集NTM感染患者临床NTM分离株99株,其中快速生长分枝杆菌(RGM)30株,包括脓肿分枝杆菌28株、偶发分枝杆菌2株,缓慢生长分枝杆菌(SGM)69株,包括胞内分枝杆菌55株、鸟分枝杆菌8株、堪萨斯分枝杆菌6株。鸟-胞内分枝杆菌复合群(MAC)对一线药物克拉霉素和阿米卡星较敏感,对二线药物利奈唑胺和莫西沙星耐药率>60.00%。所有RGM对阿米卡星高度敏感(100.00%),对多西环素耐药率最高(86.67%)。脓肿分枝杆菌对多种抗菌药物高度耐药,对克拉霉素存在诱导耐药。结论NTM菌种分布以胞内分枝杆菌和脓肿分枝杆菌为主。SGM和RGM分离株耐药性存在一定差异。NTM菌种鉴定和药物敏感性试验有助于综合性医院NTM感染患者的精准诊疗。

关键词：非结核分枝杆菌胞内分枝杆菌脓肿分枝杆菌鉴定耐药性

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Cobalt ions-derived nanoenzyme array for endosseous neural network reconstruction and osseointegration

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Bioactive Materials 2024年第12期42卷 1-17页

作者： Xinmei Cai meng yu Bo Li Yingang Zhang Yong Han State Key Laboratory for Mechanical Behavior of Materials Xi’an Jiaotong UniversityXi’an710049China Department of Orthopaedics The First Affiliated Hospital College of MedicineXi’an Jiaotong UniversityXi’an710061China

Interactions between bone cells and neurocytes are crucial for endosseous nerve and ensuing bone ***,absence of neural stem cells in bone makes the innervation of implant osseointegration a major ***,a nanorod-like array of sodium hydrogen titanate(ST)co-doped with Co^(2+)and Co^(3+),namely STC_(h) that behaves as a reactive oxygen species(ROS)-scavenging enzyme,was hydrothermally formed on Ti *** show that the doped Co^(2+)and Co^(3+)locate at TiO_(6) octahedral interlayers and within octahedra of STC_(h) lattice,appearing releasable and un-releasable,respectively,leading to an increase in Co^(3+)/Co^(2+)ratio and enzyme activity of the array with *** nanoenzyme-released Co^(2+)triggers macrophages(Ms)towards M1 phenotype,then the nanoenzyme scavenges extracellular ROS inducing M1-to-M2 *** neurogenic factors secreted by STC_(h)-regulated MΦs,in combination with the released Co^(2+),promote mesenchymal stem cells to differentiate into neurons and Schwann cells compared to sole Co^(2+)and ***_(h) array greatly enhances nerve reconstruction,type-H capillary formation and ensuing osseointegration in normal rat bone,and antibacteria via engulfing *** by MΦs and osteogenesis in infective *** nanoenzyme provides an alternative strategy to orchestrate endosseous nerve regeneration for osseointegration without loading exogenous neurotrophins in implants.

关键词： Cobalt ions-derived nanoenzyme Neurogenic factors Mesenchymal stem cells Neural differentiation Neurovascularized osseointegration

International carbon markets under the Paris Agreement:Basic form and development prospects

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Advances in Climate Change Research 2019年第1期10卷 21-29页

作者： GAO Shuai LI meng-yu DUAN Mao-Sheng WANG Can State Key Joint Laboratory of Environment Simulation and Pollution Control(SKLESPC) and School of EnvironmentTsinghua UniversirBeiying100084China Institute of Energy Environment and EconomyTsinghua UniversityBeijing100084China

Article 6 of the Paris Agreement introduces two international carbon markets that receive extensive attention and are expected to play an important role in the post-2020 climate *** key elements of the two international carbon markets,including the scope,the types of tradable units and the governance,are identified,as the basis to clarify their basic *** on the key issues and their different designs identified in negotiations,this study analyzes the contributions and challenges for China to participate in international carbon *** the inherent needs of climate change mitigation,climate finance,the development of a green"Belt and Road"and the China South-South cooperation in climate change,along with the existing domestic capacities on market mechanisms,this study puts forward the short-,medium-and long-term development prospects of the two international carbon markets.

关键词： Paris Agreement International carbon markets Cooperative approaches Sustainable development mechanism Climate change

Effects of UV-A exposures on longevity and reproduction in Helicoverpa armigera, and on the development of its F1 generation

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Insect Science 2011年第6期18卷 697-702页

作者： Chang-yu Zhang Jian-yu meng Xiao-Ping Wang Fen Zhu Chao-Liang Lei Hubei Insect Resources Utilization and Sustainable Pest Management Key Laboratory College of Plant Science and TechnologyHuazhong Agricultural University Wuhan China

Helicoverpa armigera adults display a conspicuous positive phototactic behavior to light stimuli, and are especially sensitive to ultraviolet （UV） light. The effects of UV-A （longwave） exposures on adult longevity and reproduction in H. armigera were investigated, as well as the development of the Ft generation. Paired adults were exposed to UV-A for various time periods （0, 1, 5 and 9 h/day）, until the end of adult life. The results showed that adult longevity decreased with increasing exposure time for both sexes, and a significant decrease was observed after exposure for 5 and 9 h/day. Fecundity increased when adults were exposed for 1 and 5 h/day, and a significant difference was observed in the 5 h/day group. Oviposition rates of females in all treatments were significantly higher than in the control. Exposure to UV-A for longer periods （5 and 9 h/day） caused a decline in cumulative survival of F1 immature stages, but no significant differences were found in egg hatch, pupation and eclosion. The developmental periods of F1 larvae were significantly prolonged after exposure to UV-A for 5 and 9 h/day. UV-A radiation had no significant effects on F1 pupal period.

关键词： development Helicoverpa armigera longevity oxidative stress,reproduction UV-A