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World Journal of Clinical Cases 2019年第1期7卷 89-94页

作者： Shi-Chang Zhang meng-Yao yu Lei Xi Jie-Xin Zhang Department of Laboratory Medicine the First Affiliated Hospital of Nanjing Medical University Department of Pathology the First Affiliated Hospital of Nanjing Medical University

BACKGROUND Cardiac toxic effect of tegafur(S-1) is extremely rare, and there has been no report on this issue so *** SUMMARY We herein report a typical case of single S-1 administration after radical operation for colon cancer. The patient had no background or medical history of acute coronary syndrome(ACS), and only aortic and coronary atherosclerosis was revealed by computed tomography(CT) before surgery. He complained of sternum pain during the fifth cycle of S-1 treatment. Electrocardiogram(ECG)and serum cardiac marker cardiac troponin T(cTnT) strongly suggested ACS,which was possibly caused by S-1 *** Monitoring protocols based on ECG, CT, and cTnT should be performed in real time to evaluate cardiac function during S-1 administration.

关键词： S-1 Acute coronary syndrome Computed tomography Electrocardiogram Cardiac troponin T Case report

Prostate artery embolization on lower urinary tract symptoms related to benign prostatic hyperplasia: A systematic review and metaanalysis

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World Journal of Clinical Cases 2022年第32期10卷 11812-11826页

作者： Xiao-Yan Wang yu-meng Chai Wen-Hui Huang Yong Zhang Department of Urology Beijing Tiantan HospitalCapital Medical UniversityBeijing 100070China School of Information Science and Engineering Shandong Normal UniversityJinan 250014Shandong ProvinceChina

BACKGROUND Prostate artery embolization(PAE)is a promising minimally invasive therapy that improves lower urinary tract symptoms(LUTS)related to benign prostatic hyperplasia(BPH).Transurethral resection of the prostate(TURP)is the gold standard therapy for LUTS/*** To evaluate the efficacy and safety of PAE vs TURP on LUTS related to *** A literature review was performed to identify all published articles on PAE vs TURP for LUTS/*** included PubMed,Embase,Cochrane library databases,and Chinese databases before June 2022.A systematic review and meta-analysis were *** measurements were combined by calculating the mean difference with a 95%confidence *** analysis was carried out using Review Manager *** Eleven studies involving 1070 participants were *** with the TURP group,the PAE group had a similar effect on the International Index of Erectile Function(IPSS)score,Peak urinary flow rate(Qmax),postvoid residual volume(PVR),Prostate volume(PV),prostatic specific antigen(PSA),The International Index of Erectile Function short form(IIEF-5)scores,and erectile dysfunction during 24 mo *** quality of life(QoL)score,lower rate of retrograde ejaculation and shorter hospital stay in the PAE *** was no participant death in either group.A higher proportion of haematuria,urinary incontinence and urinary stricture was identified in the TURP *** PAE may be an appropriate option for elderly patients,patients who are not candidates for surgery,and patients who do not want to risk the potential adverse effects of *** with large cases and long follow-up time are needed to validate results.

关键词： Lower urinary tract symptoms Benign prostatic hyperplasia Meta-analysis Prostate artery embolization Transurethral resection of the prostate

Effect of mold and core preheating temperature on corrosion resistance of casting Al-12Si alloy U-shaped cooling channel

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China Foundry 2023年第3期20卷 218-224页

作者： Guang-long Li Jie Zhang meng-yu Wang Rui-ming Su Yang Cao Ying-dong Qu School of Materials Science and Engineering Shenyang University of TechnologyShenyang 110870China Key Laboratory of Light Metal Materials and Engineering at Universities of Liaoning Province Shenyang University of TechnologyShenyang 110870China

Temperature has an important impact on the corrosion resistance of mold with cooling channels prepared by casting *** effect of preheating temperature of the mold and the carbon fiber core on the roughness and corrosion resistance of U-shaped cooling channels made of Al-12Si alloy was examined in *** experimental results suggest that as the preheating temperature increased from 273 K to 573 K,the roughness of the inner wall of the cooling channel reduced from 96.6μm to 77.0μ*** the preheating temperature continued to increase to 723 K,the roughness increased to 85.3μ*** wetting between the Al melt and the carbon fiber will reduce micro bubbles and waves on the channel wall as the preheating temperature rises,thereby reducing the ***,with the further increase of preheating temperature,it will increase the solidification time of the Al *** this time,the carbon fiber and Al melt will take more time to react,which increases the roughness of the channel wall to a certain *** results of exfoliation corrosion show that the larger roughness will aggravate exfoliation *** prolongation of high temperature reaction time between the carbon fiber and the Al melt will lead to the segregation of Si,which is easy to cause intergranular ***,reasonable preheating temperature has an important impact on the roughness and corrosion resistance of U-shaped cooling channels.

关键词： U-shaped cooling channels roughness exfoliation corrosion intergranular corrosion

Numerical Simulation of Water Entry of Wedges in Waves Using A CIPBased Model

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China Ocean Engineering 2021年第1期35卷 48-60页

作者： HU Zi-jun ZHAO Xi-zeng LI meng-yu ZHAO Xin YAO Wen-wei SHAO Jie Zhejiang Institute of Hydraulic and Estuary Hangzhou 310020China Ocean College Zhejiang UniversityZhoushan 316021China

In this study,the water entry of wedges in regular waves is numerically investigated by a two-dimensional in-house numerical *** numerical model based on the viscous Navier−Stokes(N−S)equations employs a high-order different method—the constrained interpolation profile(CIP)method to discretize the convection term.A Volume of Fluid(VOF)-type method,the tangent of hyperbola for interface capturing/slope weighting(THINC/SW)is employed to capture the free surface/interface,and an immersed boundary method is adopted to treat the motion of *** momentum source function derived from the Boussinesq equation is applied as an internal wavemaker to generate regular *** accuracy of the numerical model is validated in comparison with experimental results in the *** results of water entry in waves are provided in terms of the impact force of wedge,velocity and pressure distributions of *** attention is paid to the effects of wave parameters and the position of wedge impacting the water *** is found that the existence of waves significantly influences the velocity and pressure field of fluid and impact force on the wedges.

关键词： Water entry water wave wedge internal wave maker CIP method VOF method

Distinctive Polymorphism-like Isodimorphism in Poly(propylene succinate-ran-propylene fumarate)

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Chinese Journal of Polymer Science 2022年第6期40卷 602-610页

作者： Xue-Wei Wei Xin-Xin Zhao Yi Li Xiao-yu meng Qiong Zhou Hai-Mu Ye Department of Materials Science and Engineering College of New Energy and MaterialsChina University of PetroleumBeijing 102249China

Co-crystallization of different monomeric units fundamentally contributes to the versatile and tunable performance of random *** present,the crystallization manners of random binary copolymers have been divided into three categories:isomorphism,isodimorphism and comonomer *** category,however,has its own advantages and ***,it is challenging to design and prepare random copolymer sharing the advantages of isomorphism and isodimorphism through a new co-crystallization manner beyond the ones already *** the basis of previous study on poly(alkylene succinate-ran-alkylene fumarate)whose co-crystallization can be extensively and finely regulated by simply varying the chemical structure of alkylene,random copolymers of poly(propylene succinate-ranpropylene fumarate)(PPSF)are synthesized using 1,3-propanediol as the diol *** thermal properties and crystal structure of PPSF are investigated,and,intriguingly,it is proved that PPSF is an isodimorphism system while displays similar composition-dependent thermal properties and crystallinity as *** is,PPSF exhibits a novel co-crystallization behavior that has rarely been discovered,which would combine the advantages of both isomorphism and ***,PPSF could be termed as a new-type,special compositiondependent ***,the altering of PPS-like to PPF-like crystal structure of PPSF when changing chain composition has been proved to originate from the shift of dominant inter-segment interaction from van der Waals forces to strong hydrogen-bonding *** work enriches the co-crystallization manner of random copolymers,leading to more diverse performance design of polymer materials.

关键词： Co-crystallization Random copolymer Isodimorphism Inter-segment interaction

Multifunctional Sodium Gluconate Electrolyte Additive Enabling Highly Reversible Zn Anodes

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Chemical Research in Chinese Universities 2024年第4期40卷 722-729页

作者： ZHAO Kang ZHAO Jianan yu meng LIU Fangming DONG Yang WANG Shiwen CHENG Fangyi College of Chemistry Nankai UniversityTianjin300071P.R.China College of New Energy Zhengzhou University of Light IndustryZhengzhou450002P.R.China

Sodium gluconate(SG)is reported as an electrolyte additive for rechargeable aqueous zinc *** SG addition is proposed to modulate the nucleation overpotential and plating behaviors of Zn by forming a shielding buffer layer because of the adsorption priority and large steric hindrance effect,which contributes to limited rampant Zn^(2+)diffusion and mitigated hydrogen evolution and *** the introduction of 30 mmol/L SG in 2 mol/L ZnSO_(4)electrolyte,the Zn anode harvests a reversible cycling of 1200 h at 5 mA/cm^(2)and a high average Coulombic efficiency of Zn plating/stripping(99.6%).Full cells coupling Zn anode with V_(2)O_(5)·1.6H_(2)O or polyaniline cathode far surpass the SG additivefree batteries in terms of cycle stability and rate *** work provides an inspiration for design of a high-effective and low-cost electrolyte additive towards Zn-based energy storage devices.

关键词： Electrolyte additive Zn anode Sodium gluconate Adsorption Zn dendrite

Selective nitrogen doping on carbon cloth to enhance the performance of zinc anode

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Chinese Chemical Letters 2021年第3期32卷 1095-1100页

作者： Lei Wang Guilan Fan Jiuding Liu Le Zhang meng yu Zhenhua Yan Fangyi Cheng Key Laboratory of Advanced Energy Materials Chemistry(Ministry of Education) Renewable Energy Conversion and Storage CenterCollege of ChemistryNankai UniversityTianjin 300071China

Metallic zinc is attractive anode material of rechargeable aqueous Zn-based batteries due to its ambient stability,high volumetric capacity,and abundant ***,Zn anodes suffer from issues such as low coulombic efficiency(CE),large polarization and dendrite ***,uniform Zn electrodeposition is reported on carbon substrates by selective nitrogen *** experimental and theoretical investigations demonstrate that pyrrolic and pyridinic nitrogen doped in carbon play beneficial effect as zinc-philic sites to direct nucleation and growth of metallic Zn,while negligible effect is observed for graphite nitrogen in Zn *** carbon cloth with modified amount of doped pyrrolic and pyridinic nitrogen stabilizes Zn plating/stripping with 99.3%CE after 300 cycles and significantly increases the deliverable capacity at high depth of charge and discharge compared to undoped carbon substrate and Zn *** work provides a better understanding of heteroatom doping effect in design and preparation of stable 3 D carbon-supported zinc anode.

关键词： Zinc Batteries Nitrogen doping Carbon substrate Electrodeposition

Defense of COVID-19 by Human Organoids

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Phenomics 2021年第3期1卷 113-128页

作者： Ting Lv Fanlu meng meng yu Haihui Huang Xinhua Lin Bing Zhao State Key Laboratory of Genetic Engineering School of Life SciencesZhongshan HospitalFudan UniversityShanghai 200438China Institute of Antibiotics Huashan HospitalFudan UniversityShanghai 200040China Shandong Key Laboratory of Biophysics Institute of BiophysicsDezhou UniversityDezhou 253023China

Coronavirus disease 2019(COVID-19),caused by severe acute respiratory syndrome coronavirus-2(SARS-CoV-2),has created an immense menace to public health worldwide,exerting huge effects on global economic and political *** the biology and pathogenesis mechanisms of this novel virus,in large parts,relies on optimal physiological models that allow replication and propagation of *** organoids,derived from stem cells,are three-dimen-sional cell cultures that recapitulate the cellular organization,transcriptional and epigenetic signatures of their counterpart *** studies have indicated their great values as experimental virology platforms,making human organoid an ideal tool for investigating host-pathogen ***,we summarize research developments for SARS-CoV-2 infection of various human organoids involved in multiple systems,including lung,liver,brain,intestine,kidney and blood vessel *** studies help us reveal the pathogenesis mechanism of COVID-19,and facilitate the development of effec-tive vaccines and drugs as well as other therapeutic regimes.

关键词： COVID-19 Human organoids SARS-CoV-2 infection Multi-organ damage Drug discovery

Concurrent recycling chemistry for cathode/anode in spent graphite/LiFePO_(4) batteries:Designing a unique cation/anion-co-workable dual-ion battery

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Journal of Energy Chemistry 2022年第1期31卷 166-171,I0005页

作者： yun-Feng meng Hao-Jie Liang Chen-De Zhao Wen-Hao Li Zhen-Yi Gu meng-Xuan yu Bo Zhao Xian-Kun Hou Xing-Long Wu Faculty of Chemistry Northeast Normal UniversityChangchun 130024JilinChina MOE Key Laboratory for UV Light-Emitting Materials and Technology Northeast Normal UniversityChangchun 130024JilinChina

With the increasing popularity of new en ergy electric vehicles,the dema nd for lithium-ion batteries(LIBs)has been growing rapidly,which will produce a large number of spent ***,recycling of spe nt LIBs has become an urge nt task to be solved,otherwise it will inevitably lead to serious environmental ***,a unique recycling strategy is proposed to achieve the concurrent reuse of cathode and anode in the spent graphite/LiFePO_(4) *** with such recycling process,a unique cathode composed of recycled LFP/graphite(RLFPG)with cation/anion-co-storage ability is designed for new-type dual-ion battery(DIB).As a result,the recycle-derived DIB of Li/RLFPG is established with good electrochemical performance,such as an initial discharge capacity of 117.4 mA h g^(-1) at 25 mA g^(-1) and 78% capacity retention after 1000 cycles at 100 mA g^(-1).The working mechanism of Li/RLFPG DIB is also revealed via in situ X-ray diffraction and electrode kinetics *** work not only presents a farreaching significance for large-scale recycling of spent LIBs in the future,but also proposed a sustainable and econo mical method to design n ew-type sec on dary batteries as recycling of spe nt LIBs.

关键词： Dual-ion batteries LiFePO_(4) Graphite Spenr lithium-ion batteries Recycle

Thin-walled and large-sized magnesium alloy die castings for passenger car cockpit:Application,materials,and manufacture

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China Foundry 2024年第5期21卷 525-545页

作者： Lei Zhan yu-meng Sun Yang Song Chun-hua Kong Kai Ma Bai-xin Dong Hong-yu Yang Shi-li Shu Feng Qiu School of Automotive Engineering Jilin Communication PolytechnicChangchun 130012China Key Laboratory of Automobile Materials of Ministry of Education School of Materials Science and EngineeringNanling CampusJilin UniversityChangchun 130025China

In order to effectively reduce energy consumption and increase range mile,new energy vehicles represented by Tesla have greatly aroused the application of integrated magnesium(Mg)alloy die casting technology in ***,the application of Mg alloys in automobiles,especially in automotive cockpit components,is quite extensive,while it has almost disappeared for a period of time due to its relatively high cost,causing a certain degree of information loss in the application technology of Mg alloy parts in *** rapid development of automotive technology has led to a higher requirement for the automotive components compared with those traditional ***,whatever the components themselves,or the Mg alloy materials and die casting process have to face an increasing challenge,needing to be *** addition,owing to its high integration characteristics,the application of Mg alloy die casting technology in large-sized and thin-walled automotive parts has inherent advantages and needs to be expanded ***,it necessitates exploring advance Mg alloys and new product structures and optimizing die casting *** article summarizes and analyzes the development status of thin-walled and large-sized die casting Mg alloy parts in passenger car cockpit and corresponding material selection methods,die casting processes as well as mold design ***,this work will aid researchers in establishing a comprehensive understanding of the manufacture of thin-walled and large-sized die casting Mg alloy parts in automobile *** will also assist them in developing new Mg alloys with improved comprehensive performance and new processes to meet the high requirements for die casting automotive components.

关键词： Mg alloys thin wall large size automotive part die casting