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Stochastic Workflow Nets Based Workflow Pattern Modeling

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Chinese Journal of Electronics 2014年第1期23卷 6-12页

作者： ZHOU Huan LIN Chuang meng Kun CHEN Yarui Tsinghua National Laboratory for Information Science and Technology Department of Computer Science and Technology Tsinghua University

Petri nets are widely used in describing workflow models of management systems, and also functioning in process management and resource *** number of workflow patterns are increasing along with the demands of business process modeling. The Petri net and its extensions can no longer meet the requirement of model description, due to the limitation of their *** models of some patterns are very sophisticated and even grow exponentially in complexity. Also the performance of these new patterns are not well studied. This paper extends Petri nets to Stochastic workflow nets(SWNs)and introduces stochastic or state related variables into arc weights, transition enabling guard and execution *** the new features, SWNs can describe models more accurately and flexibly. And performance of common patterns is calculated under the assumption of exponentially distributed time. The paper also illustrates how to simplify the model with equivalent patterns.

关键词： Stochastic workflow nets Workflow patterns Performance analysis

Relationship Between Built Environment, Socio-economic Factors and Carbon Emissions from Shopping Trip in Shenyang City, China

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Chinese Geographical Science 2017年第5期27卷 722-734页

作者： LI Jing LO Kevin ZHANG Pingyu GUO meng Northeast Institute of Geography and Agroecology Chinese Academy of Sciences Department of Geography Hong Kong Baptist University School of Geographical Science Northeast Normal University

Promoting active travel behavior and decreasing transport-related carbon dioxide （CO2） emissions have become a priority in many Chinese cities experiencing rapid urban sprawl and greater automobile dependence. However, there are few studies that holistically examine the physical and social factors associated with travel CO2 emissions. Using a survey of 1525 shoppers conducted in Shenyang, China, this study estimated shopping-related travel CO2 emissions and examined how the built environment and individual socioeconomic characteristics contribute to shopping travel behavior and associated C02 emissions. We found that, firstly, private car trips generate nearly eight times more carbon emissions than shopping trips using public transport, on average. Second, there was sig- nificant spatial autocorrelation with CO2 emissions per trip, and the highest carbon emissions were clustered in the inner suburbs and between the first and second circumferential roads. Third, shopping travel CO2 emissions per trip were negatively correlated with sev- eral built environment features including population density, the quantity of public transport stations, road density, and shop density. They were also found to be significantly related to the individual socio-eeonomic characteristics of car ownership, employment status, and education level using a multinomial logistic regression model. These empirical findings have important policy implications, assisting in the development of measures that contribute to the sustainability of urban transportation and meet carbon mitigation targets.

关键词： transport carbon emission travel behavior built environment socio-economic factors shopping trips China

Organic fluorescent probes for live-cell super-resolution imaging

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Frontiers of Optoelectronics 2023年第4期16卷 25-36页

作者： Xinxin Duan meng Zhang Yu‑Hui Zhang Britton Chance Center for Biomedical Photonics MoE Key Laboratory for Biomedical PhotonicsAdvanced Biomedical Imaging Facility-Wuhan National Laboratory for OptoelectronicsHuazhong University of Science and TechnologyWuhan 430074China

The development of super-resolution technology has made it possible to investigate the ultrastructure of intracellular organelles by fuorescence microscopy,which has greatly facilitated the development of life sciences and *** realize super-resolution imaging of living cells,both advanced imaging systems and excellent fuorescent probes are *** fuorescent probes have good availability,but that is not the case for probes for live-cell super-resolution *** this review,we frst introduce the principles of various super-resolution technologies and their probe requirements,then summarize the existing designs and delivery strategies of super-resolution probes for live-cell imaging,and fnally provide a brief conclusion and overview of the future.

关键词： Super-resolution imaging Organic fluorescent dyes-Live-cell imaging Cell-impermeable organic probes

Oscillatory hyper Hilbert transforms along curves

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Applied Mathematics(A Journal of Chinese Universities) 2009年第3期24卷 336-342页

作者： CHEN Jie-cheng FAN Da-shan WANG meng Dept. of Math. Zhejiang University Hangzhou 310027 China Dept. of Mathematical Sciences University of Wisconsin-Milwaukee Milwaukee Wisconsin 53201

The hyper Hilbert transform Tnf（x） =∫-1^1 f（x - Γ（t））e^-i｜t｜-β｜t｜^-1-αdt along an appropriate curve Γ（t） on R^n is investigated,where β 〉 α 〉 *** L^p boundedness theorem of T4 is obtained,which is... 详细信息

关键词： hyper Hilbert transform curve

A Feedback Scheme for Fountain Codes Based Transport Protocol in Space Communications

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China Communications 2015年第8期12卷 62-72页

作者： XING Yanling GE ning Tsinghua National Laboratory for Information Science and Technology Department of Electronic Engineering Tsinghua University Aerospace Communications and Terminal Application Technologies Engineering Laboratory in Shenzhen

This paper proposed a practical- feedback scheme for fountain codes based transportprotocol in space communications. In the proposed scheme, the sender is signaled by two types of acknowledgment （ACK） *** decoding, packet loss probability isestimated on the receiver side and encapsulated intoa soft ACKand sent to the *** decoding,decoding results are encapsulated into hard ACKsandsent to the sender. There are two contributionsin the proposed scheme： 1. Empl layer calculation instead layer statistics to estimate oying physical of application the packet loss probability of space channel, which can improvethe accuracy and practicality. 2. A cascade overhead-failure probability relationship between the sender and the receiver has been analyzed to help determine the exact numberof packetsneeded byfountain *** show that for space communications,compared with the existing space transport protocols, fountain codes based transport protoeolwith the proposed schemecan not only ensure transmission reliability, but also greatly improvelink utilization.

关键词： fountain code feedback spacecommunication packet loss probabilityestimation transport protocol

Multi-objective energy management system for DC microgrids based on maximum membership degree principle

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Journal of Modern Power Systems and Clean Energy 2018年第4期6卷 668-678页

作者： Panbao WANG Wei WANG Nina meng Dianguo XU School of Electrical Engineering and Automation Harbin Institute of Technology

With the increasing quantity of DC electrical equipment, DC microgrids have been paid more and more attention. This paper proposes an approach to multi-objective optimisation of an energy management system(EMS) for a DC microgrid that includes a hybrid energy storage system(HESS). The operating and maintenance cost and the loss of power supply probability(LPSP) of the system are used as optimisation targets. The power flows of all distributed generators(DGs) in the DC microgrid during operating period are optimized. Based on the improved differential evolution(DE) algorithm, and by using the multi-objective non-dominated sorting method and the maximum membership degree principle(MMDP) of fuzzy control, the overall satisfaction degree of Pareto solutions to power flow optimization can be obtained. Simulation results verify the effectiveness of the proposed EMS optimization scheme, which is able to achieve an effective trade-off between the economy and the reliability of microgrid operation.

关键词： DC microgrids Energy management system Multi-objective optimization Differential evolution algorithm Maximum membership degree

Prevalence of liver injury among patients with acquired immunodeficiency syndrome treated with highly active antiretroviral therapy in China

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Journal of Traditional Chinese Medicine 2019年第2期39卷 275-280页

作者： Yuan Jun Xu Qianlei Chen xiumin meng Pengfei Li Qingya Xu Liran meng Xiangle Jin Yantao Guo Huijun Department of AIDS Treatment and Research Center the First Affiliated Hospital of Henan University of Traditional Chinese Medicine

OBJECTIVE: To estimate the prevalence of liver injury among patients with acquired immunodeficiency syndrome(AIDS) who received highly active antiretroviral therapy(HAART) in rural Henan Province in China, and to explore whether Traditional Chinese Medicine(TCM) treatment based on HAART would increase this ***: This was a retrospective cross-sectional study. We collected medical information on patients with AIDS from two treatment databases in2014. Criteria established by the AIDS Clinical Trials Group in 1996 were used for grading liver injury,classified based on the limit of normal(ULN) for alanine transaminase and aspartate aminotransferase:grade 1(1.25-2.5 × ULN); grade 2(2.6-5 × ULN);grade 3(5.1-10 × ULN); and grade 4(> 10 × ULN).Factors associated with liver injury were evaluated using a logistic regression ***: A total 6953 patients with AIDS(3324 male and 3629 female patients) were enrolled into this study. The prevalence of liver injury was 22.0%(18.0% grade 1, 3.1% grade 2, 0.9% grade 3). In multivariate analysis, patients aged 34-45 years were more likely to have liver injury than patients in other age groups [adjusted odds ratio(AOR), 1.39; 95%CI, 1.01-1.91)]. Other factors associated with liver injury included male sex(AOR, 1.64; 95% CI,1.46-1.85), HIV infection via blood(AOR, 1.47; 95%CI, 1.19-1.82), hepatitis B virus antibody positive(AOR, 1.07; 95% CI, 0.85-1.36), and hepatitis C virus(HCV) antibody positive(AOR, 2.76; 95% CI,2.28-3.34).CONCLUSION: The prevalence of liver injury was relatively high among HAART-experienced patients. Several factors associated with liver injury included male sex, age 35-45 years old, HIV infection through blood, and concurrent HCV infection. TCM had no relationship with liver injury in patients receiving HAART.

关键词： Acquired immunodeficiency syndrome Chemical and drug induced liver injury Prevalence Antiretroviral therapy,highly active Medicine,Chinese traditional

C-terminal domain of Chk1 regulates its subcellular location and kinase activity for DNA repair

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Chinese Science Bulletin 2011年第30期56卷 3138-3147页

作者： ning LiFeng WANG HuiPing SAN Dan SANG JianLi Key Laboratory for Cell Proliferation and Regulation Biology of Ministry of Education College of Life Science Beijing Normal University Beijing 100875 China Department of Reproduction Immunology National Research Institute for Family Planning Beifing 100081 China

Effector kinase Chk1 is an evolutionarily conserved protein kinase. It is a key mediator linking the mechanisms that monitor DNA integrity to components of the cell cycle engine. In this study, recombinant vectors pEGFP-C1-Chk1/C 288/C 334/C 368 were constructed and transfected into HeLa cells to study the effect of the Chk1 regulatory domain on the regulation of subcellular Chk1 location in response to DNA damage. We found that DNA damage-induced nuclear accumulation is regulated by 34 amino acids (334–368) in the C-terminal regulatory domain. Recombinant vectors pXJ41-Chk1/C 288/C 334/C 368 were co-transfected with reporter plasmid pEGFP-N2 into HeLa cells to study the repair abilities of the different human Chk1 truncation mutants. In addition, recombinant vectors were transfected into HeLa cells to study the effects of the different truncation mutants on the cell cycle. Furthermore, to study the kinase activity of the different truncation mutants, Ser216 phosphorylation of Cdc25C was studied by Western blot analysis. We found that the enzymatic activity of C 368, missing the 108 C-terminal amino acids (368–476), was higher than that of full-length Chk1, and C 368 delayed the cell cycle progression. The enzymatic activity of C 334, missing the 142 C-terminal amino acids (334–476), was equivalent to that of full-length Chk1. C 288, missing the 188 C-terminal amino acids (288–476), had almost no enzymatic activity, suggesting that the regulatory domain contains both inhibitory and regulatory elements. This study provides useful information for further research on Chk1 function.

关键词：亚细胞定位激酶活性 DNA修复 HeLa细胞 DNA损伤细胞周期重组载体 blot分析

Deformation Mechanism and Vertical Sealing Capacity of Fault in the Mudstone Caprock

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Journal of Earth Science 2019年第2期30卷 367-375页

作者： Xiaofei Fu Lingyu Yan Lingdong meng Xiaobo Liu Laboratory of CNPC Fault-Controlling Reservoir Northeast Petroleum University Science and Technology Innovation Team in Heilongjiang Province"Fault Deformation Sealing and Fluid Migration"Northeast Petroleum University State Key Laboratory Base of Unconventional Oil and Gas Accumulation and Exploitation Northeast Petroleum University School of Energy Resource China University of Geosciences Daqing Yushulin Oilfield Development Co.Ltd.

The petrophysical property of mudstone often transforms from ductile to brittle in the process of burial-uplift. The deformation mechanism of fault in brittle and ductile mudstone caprock is different, which leads to the formation of different types of fault zone structure. Different methods are required to evaluate the sealing mechanism of those fault zones. Based on the caprock deformation mechanism, fault sealing mechanism, quantitative evaluation method of vertical fault sealing capacity is put forward in this study. Clay smear is formed in the process of plastic deformation and its continuity controls the sealing capacity of fault. The outcrop and oil field data have confirmed that when sealing parameter SSF is less than 4–7, the clay smear becomes discontinuous and then oil and gas go through the caprock and migrate vertically. Quantities of fractures are formed in mudstone in the process of brittle deformation. The fracture density increases with the increase of the fault displacement. When the fractures are connected, oil and gas go through the caprock and migrate vertically. The connectivity of fault depends on the displacement and the thickness of caprock. On the basis of the above, a method is put forward to quantify the connectivity of fault with the juxtaposition thickness of caprock after faulting. The research on the juxtaposition thickness of caprock after faulting of the member II of Dongying Formation in Nanpu depression and the distribution of oil and gas indicates when the juxtaposition thickness of caprock is less than 96.2 m, the fault becomes leaking vertically. In the lifting stage, with the releasing and unloading of the stress, the caprock becomes brittle generally and then forms through going fault which will lead to a large quantity of oil and gas migrate vertically.

关键词： mudstone fault deformation brittle-ductile shale smear CJT quantitative evaluation