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Validation of the TOPAS Monte-Carlo Code of the Off-Field Dose of a 6 MV Synergy l.nac

Journal of Biosciences and Medicines 2024年第7期12卷 38-54页

作者： Kodjo Joel Fabrice n’Guessan Ibrahima Sakho Bogbé D. l. H. Gogon Department of Physics and Chemistry Faculty of Sciences and Technology Iba Der Thiam University of This This Senegal International Cancer Center of Dakar Dakar Senegal Department of Physics Faculty of Sciences and Technology Flix Houphouet Boigny University of Abidjan Abidjan Cte dIvoire

The risk of radiation-induced second cancer and the late tissue loss due to Off-field doses in radiotherapy remain a serious concern. Monte Carlo (MC) simulation is currently one of the most accurate methods for calculating these doses. MC simulation model based on the Particle Simulation Tool (TOPAS) has been developed to simulate the off-field dose of an Elekta Synergy l.near accelerator (l.nac) emitting 6 MV photons. Measurements were taken in a water phantom using an ionization chamber to validate this model. The Percentage Depth Dose (PDD) at the depth of 0.0, 5.0, 10.0 and 15.0 cm from the beam axis for a 10 × 10 cm2 field size was measured and simulated. Off-field dose profiles at the depth of 1.5 (dmax), 5.0 and 10.0 cm for field sizes of 5 × 5, 10 × 10, 15 × 15, and 20 × 20 cm2 respectively were measured and simulated. Comparison of measured and simulated off-field dose values showed a good agreement. The average gamma passing rate of the PDDs and profiles curves for off-field doses were 87.5% and 98.11% respectively. The local dose difference based on the PDD curve between the measured and simulated was less than 6.0 % for all locations. For all field size considered in this study, the average difference between profile curves for off-field dose measured and simulated was 9.1%. PDDs and Profiles curves for off-field dose simulation uncertainties were less than 2.0% and 1.0% respectively. TOPAS-MC simulation model developed is a good representation of our 6 MV l.nac Elekta Synergy for assessing off-field dose, which would be the primary cause of some secondary cancers.

关键词： Radiotherapy Off-Field Dose Secondary Cancer TOPAS-MC Simulation Dosimetry

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Biomass gasification,catalytic technologies and energy integration for production of circular methanol.new horizons for industry decarbonisation

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Journal of Environmental Sciences 2024年第6期140卷 306-318页

作者： luis F.Bobadilla lola Azancot Miriam González-Castañ Estela Ruíz-lópez laura Pastor-Pérez Francisco J.Durán-Olivencia Runping Ye Katie Chong Paula HBl.nco-Sánchez Zenthao Wu Tomás R.Reina JoséA.Odriozola Departamento de Química Inorgánica e Instituto de Ciencia de Materiales de Sevilla Centro Mixto CSIC-Universidad de SevillaAvda.Américo Vespucio 49Sevilla 41092Spain Departamento de Ingeniería Universidad Loyola AndalucíaAvda.de Las Universidades s/nSevilla 41704Spain Key laboratory of Jiangxi Province for Environment and Energy Catalysis School of Chemistry and Chemical EngineeringNanchang UniversityNanchang330031China Energy and Bioproducts Research Institute(EBRI) Aston UniversityBirminghamB47ETUnited Kingdom Department of Chemical and Process Engineering University of SurreyGuildfordGU27XHUnited Kingdom

The Intergovernmental Panel on Climate Change(IPCC)recognises the pivotal role of renewable energies in the future energy system and the achievement of the zero-emission *** implementation of renewables should provide major opportunities and enable a more secure and decentralised energy supply *** fuels provide l.ng-term solutions for the transport sector,particularly for applications where fuels with high energy density are *** addition,it helps reducing the carbon footprint of these sectors in the *** on biomass characteristics feedstock is essential for scal.ng-up gasification from the laboratory to *** review deals with the transformation biogenic residues into a valuable bioenergy carrier like biomethanol as the liquid sunshine based on the combination of modified mature technologies such as gasification with other innovative solutions such as membranes and microchannel *** abatement is a critical process in product gas upgrading since tars compromise downstream processes and equipment,for this,membrane technology for upgrading syngas quality is discussed in this *** reactor technology with the design of state-of-the-art multifunctional catalysts provides a path to develop decentralised biomethanol synthesis from biogenic ***,the development of a process chain for the production of(i)methanol as an intermediate energy carrier,(ii)electricity and(iii)heat for decentralised applications based on biomass feedstock flexible gasification,gas upgrading and methanol synthesis is analysed.

关键词： Biogenic residues Gasification Biomethanol Circular Economy Microreactors

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A novel diagnostic gene region for distinguishing between two pest fruit flies:Bactrocera tryoni(Froggatt)and Bactrocera neohumeralis(Hardy)(Diptera:Tephritidae)

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Insect Science 2024年第4期31卷 1285-1295页

作者： Melissa l.Starkie Elizabeth V.Fowler Alexander M.Piper Xiaocheng Zhu Paul.ne Wyatt David Gopurenko Matt n.Krosch Francesca Strutt Karen F.Armstrong Hamish Patrick Mark K.Schutze Mark J.Blacket Department of Agriculture and Fisheries BiosecurityBrisbaneQueenslandAustralia Agriculture Victoria AgriBioBundooraVictoriaAustralia Department of Primary Industries Wagga Wagga Agricultural InstituteWagga WaggaNew South WalesAustralia Forensic Services Group Queensland Police ServiceBrisbaneQueenslandAustralia Department of Pest-management and Conservation Lincoln UniversityLincolnNew Zealand Better Border Biosecurity(B3 B3nz.org.nz)LincolnNew Zealand

Bactrocera tryoni and Bactrocera neohumeralis are morphologically similar sibl.ng pest fruit fly species that possess different biological attributes,geographic distributions,and host *** need to differentiate between the two species is critical for accurate pest status assessment,management,biosecurity,and maintenance of reference *** morphologically similar,adults may be separated based on subtle characters;however,some characters exhibit intraspecific variability,creating overlap between the two ***,there is currently no single molecular marker or rapid diagnostic assay that can reliably distinguish between *** and ***;therefore,ambiguous samples remain *** we report the first molecular marker that can consistently distinguish between *** and *** diagnostic region consists of two adjacent single nucleotide polymorphisms(SnPs)within the pangol.n(pan)gene *** confirmed the genotypes of each species are consistent across their distributional range,then developed a tetra-primer amplification refractory mutation system(ARMS)PCR assay for rapid diagnosis of the *** assay utilizes four primers in multiplex,with two outer universal primers,and two internal primers:one designed to target two adjacent SnPs(AA)present in *** and the other targeting adjacent SnPs present in ***(GG).The assay accurately discriminates between the two species,but their SnP genotypes are shared with other nontarget tephritid fruit fly ***,this assay is most suited to adult diagnostics where species confirmation is necessary in determining ambiguous surveill.nce trap catches;maintaining pure col.ny l.nes;and in Sterile Insect Technique management responses.

关键词： ARMS-PCR col.ny molecular diagnostics pangol.n tetra-primer

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Single atom Cu-n-C catalysts for the electro-reduction of CO_(2) to CO assessed by rotating ring-disc electrode

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Journal of Energy Chemistry 2024年第1期88卷 169-182,I0004页

作者： S.Pérez-Rodríguez M.Gutiérrez-Roa C.Giménez-Rubio D.Ríos-Ruiz P.Arévalo-Cid M.V.Martínez-Huerta A.Zitolo M.J.lázaro D.Sebastián Instituto de Carboquímica(CSIC) Miguel Luesma Castán 450018 ZaragozaSpain Instituto de Catálisis y Petroleoquímica(CSIC) Marie Curie 228049 MadridSpain Synchrotron SOlEIl L’Orme des MerisiersDépartementale 12891190France

The electrochemical CO_(2) reduction reaction(CO_(2)RR) to controllable chemicals is considered as a promising pathway to store intermittent renewable energy. Herein, a set of catalysts based on copper-nitrogendoped carbon xerogel(Cu-n-C) are successfully developed varying the copper amount and the nature of the copper precursor, for the efficient CO_(2)RR. The electrocatalytic performance of Cu-n-C materials is assessed by a rotating ring-disc electrode(RRDE), technique still rarely explored for CO_(2)RR. For comparison, products are also characterized by onl.ne gas chromatography in a H-cell. The as-synthesized Cu-nC catalysts are found to be active and highly CO selective at low overpotentials(from -0.6 to -0.8 V ***) in 0.1 M KHCO_(3), while H_(2) from the competitive water reduction appears at larger overpotentials(-0.9 V vs. RHE). The optimum copper acetate-derived catalyst containing Cu-n_(4) moieties exhibits a CO_(2)-to-CO turnover frequency of 997 h^(-1) at -0.9 V vs. RHE with a H_(2)/CO ratio of 1.8. These results demonstrate that RRDE configuration can be used as a feasible approach for identifying electrolysis products from CO_(2)RR.

关键词： Cu-n-C Carbon xerogel Rotating ring disc electrode Carbon dioxide reduction reaction Carbon monoxide

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Avian responses to an extreme weather event:The case of the‘Filomena’snowstorm in Madrid(central Spain)

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Avian Research 2024年第2期15卷 180-186页

作者： Carlos lazaro Carlos Sanchez-García Fabian Casas E.Jorge Tizado Department of Research Fundacion Artemisan13001 Ciudad RealSpain Department of Zoology Faculty of SciencesUniversity of GranadaGranadaSpain Department of Biodiversity and Environmental Management Universidad de Leon24401 PonferradaSpain

Cold spells and severe weather may have detrimental effects in wild birds,but owing to the stochastic nature of these events,it is not always possible to measure their *** January 2021,a strong snowstorm known as‘Filomena’affected Spain,mainly the region of Madrid(Central Spain),which was fully covered with snow and suffered freezing temperatures for a *** bird surveys conducted in the winter-spring of 2020 and 2021(before and after Filomena)at same locations,we addressed the possible impact of the cold spell in three widespread gamebirds:Wood Pigeon(Columba palumbus),Eurasian Magpie(Pica pica)and Red-legged Partridge(Alectoris rufa).no significant abundance differences were found between years for none of the species and hunting pressure was only significantly reduced for Partridges,hence this species may have been negatively affected by *** suggest that in response to Filomena,Pigeons conducted partial migration in search of better conditions,while Magpies aggregated in certain areas of Madrid and Partridges endured the harsh conditions within their home *** results highlight the importance to alleviate negative impacts of extreme weather events in wild birds through management actions,especially for sedentary species.

关键词： Alectoris rufa Climate change Cold spell Columba palumbus Migration Pica pica Winter

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living in a Condominium Regime:neighborhood Conflicts in low-Income Housing,Tijuana,Baja California-A Secondary Publication

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Journal of World Architecture 2024年第2期8卷 96-107页

作者： M.Zárate lópez A.Almejo Ornelas M.Sahagún Val.nzuela Autonomous University of Baja California Mexico

This paper analyzes neighborhood conflicts arising from the condominium property regime,under which social housing promoted by Mexican government institutions and private developers is *** regime has facilitated access to housing for the salaried population,but it is far from contributing to the attainment of the right to *** research takes as case studies housing complexes located in the city of Tijuana,Baja California,*** analysis included a mixed ***,similar case studies were analyzed;secondly,a review of the Condominium Property Regime law was carried out in order to understand its *** view of the pandemic situation,a virtual survey was applied to the inhabitants of these areas,as well as interviews with presidents of neighborhood committees of these *** the above,it was found that this form of ownership generates conflicts,reflected in the dissatisfaction of the inhabitants with their housing,disagreements and controversies in their organization and *** inhabitants have to collectively solve the problems they face,related to the maintenance and use of common areas,insecurity,and cleanl.ness,among *** addition,there is a lack of support from local *** this,it is concluded that although the inhabitants have a space that solves their housing problem,it does not manage to be a space that adequately guarantees their right to housing.

关键词： neighborhood conflicts Right to housing Condominium property Social interest Affordable housing

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服务业数字投入、本土市场规模与国内分工深化——兼论产业链外部风险

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经济学动态 2024年第4期 49-69页

作者：王岚程志宙天津财经大学数字经济与管理学院 300222 中央财经大学国际经济与贸易学院 100081

数字经济改变了服务业“不可贸易”和“低效率”的传统属性,为中国依托国内大市场实现服务业高质量发展、打造内需主导型价值链提供了新的契机。本文从国内生产链长视角考察数字投入对服务业国内分工深化的作用机制和效果。结果表明:数... 详细信息

数字经济改变了服务业“不可贸易”和“低效率”的传统属性,为中国依托国内大市场实现服务业高质量发展、打造内需主导型价值链提供了新的契机。本文从国内生产链长视角考察数字投入对服务业国内分工深化的作用机制和效果。结果表明:数字投入一方面能通过提升全要素生产率和资源配置效率显著增加国内生产链长,促进国内分工深化;另一方面能通过降低劳动力比较优势的重要性,推进高收入国家的国内分工深化。本土市场规模会产生逆向牵引和虹吸效应,从而强化数字投入的分工深化作用。这一结论在更靠近需求端的下游行业和门槛效应分析中得到了论证。异质性分析表明,数字投入对生产性服务业的分工深化作用更明显;数字产品投入和国外投入对国内分工深化有着显著的抑制作用;与此同时,适度降低跨境数据流动限制有利于强化分工深化效应。拓展分析表明,数字投入会通过降低生产过程外部风险提升产业链安全,本土市场规模在这过程中发挥了“蓄水池”和“压舱石”的作用。以上研究结论对于中国打造内需主导型服务业价值链,实现服务业提质增效和产业链安全稳定提供了理论和事实依据。

关键词：数字化投入生产链条长度分工深化本土市场规模外部风险

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Impact of payment source, referral site, and place of residence on outcomes after allogeneic transpl.ntation in Mexico

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World Journal of Transpl.ntation 2024年第2期14卷 76-87页

作者： Andrés Gómez-De león Yesica A lópez-Mora Valeria García-Zárate Ana Varela-Constantino Sergio U Villegas-De leon Xitlaly J González-leal Raúl del Toro-Mijares Anna C Rodríguez-Zúñiga Juan F Barrios-Ruiz Victor Mingura-ledezma Perla R Col.nga-Pedraza Olga G Cantú-Rodríguez César H Gutiérrez-Aguirre luz Tarín-Arzaga Elías E González-lópez David Gómez-Almaguer Hematology Service Universidad Autónoma de Nuevo LeónFacultad de Medicina y Hospital Universitario Dr.JoséEleuterio GonzálezMonterrey 64460Nuevo LeónMexico Hemato-logy Service Clínica Gómez AlmaguerMonterrey 64710Nuevo LeónMexico Hematology Service Instituto Tecnológico de Estudios Superiores de MonterreyTec SaludEscuela de Medicina Ignacio SantosMonterrey 64710Nuevo LeónMexico

BACKGROUnD The impact of social determinants of health in allogeneic transpl.nt recipients in low-and middle-income countries is poorly *** observational study analyzes the impact of place of residence,referring institution,and transpl.nt cost coverage(out-of-pocket vs government-funded vs private insurance)on outcomes after allogeneic hematopoietic stem cell transpl.ntation(alloHSCT)in two of Mexico's largest public and private *** To evaluate the impact of social determinants of health and their relationship with outcomes among allogeneic transpl.nt recipients in *** In this retrospective cohort study,we included adolescents and adults≥16 years who received a matched sibl.ng or haploidentical transpl.nt from *** were selected without regard to their diagnosis and were sourced from both a private cl.nic and a public University Hospital in *** payment groups were compared:Out-of-pocket(OOP),private insurance,and a federal Universal healthcare program“Seguro Popular”.Outcomes were compared between referred and institution-diagnosed patients,and between residents of nuevo leon and *** outcomes included overall survival(OS),categorized by residence,referral,and payment *** outcomes encompassed early mortality,event-free-survival,graft-versus-host-relapse-free survival,and non-relapse-mortality(nRM).Statistical analyses employed appropriate tests,Kapl.n-Meier method,and Cox proportional hazard regression *** software included SPSS and R with tidycmprsk *** Our primary outcome was overall *** included 287 patients,n=164 who lived out of state(57.1%),and n=129 referred from another institution(44.9%).The most frequent payment source was OOP(n=139,48.4%),followed by private insurance(n=75,26.1%)and universal coverage(n=73,25.4%).no differences in OS,event-free-survival.nRM,or graft-versus-host-relapse-free survival were observed for patients dia

关键词： Hematopoietic cell transpl.nt Social determinants of health Geography Haploidentical Out-of-pocket Financial toxicity Survival Health services and outcomes Hematopoietic malignancy Aplastic anemia

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A nano-plasmonic HMIM waveguide based concurrent dual-band BPF using circular ring resonator

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Optoelectronics letters 2024年第3期20卷 152-156页

作者： Miriyala Sridhar Surendra Kumar Bitra TS n Murthy Koppireddi Padmaraju Department of Electronics and Communication Engineering Koneru Lakshmaiah Education FoundationGunturIndia Astra Microwave Products ltd. HyderabadIndia Department of Electronics and Communication Engineering JNTU-GV College of EngineeringVizianagaramIndia Department of Electronics and Communication Engineering Jawaharlal Nehru Technological University KakinadaKakinadaIndia

This article analyzes the transmission l.ne characteristics of plasmonic hybrid metal insulator metal(HMIM) wave-guide, circular ring resonator(CRR) based dual-band band-pass filters with two transmission poles in both pass-bands in the optical regime using coupled l.ne feed. The transmission l.ne characteristics of an HMIM waveguide, such as characteristic impedance(Z_(PV)), effective refractive index(n_(eff)) and propagation l.ngth(l_(spp)), have been obtained by using full wave simulation.

关键词： waveguide resonator circular

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Oligodendroctyes:the forgotten players of diabetes pathophysiology

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neural Regeneration Research 2024年第11期19卷 2349-2350页

作者： Juan Antonio lópez-Villodres Beatriz García-Díaz Departamento Fisiología Humana Histología HumanaAnatomía Patológica y Educación Física y DeportivaFacultad de MedicinaUniversidad de MálagaMálagaSpain UGC neurociencia.Instituto de Investigación Biomédica de Málaga y Plataforma en nanomedicina(IBIMA Plataforma Bionand) MálagaSpain

Oligodendrocytes(Ols),glial cells that provide myel.n sheaths to axons in the central.nervous system(CnS),have a dual ***,this myel.n fatty cover around the axons protects the nerves and is crucial for the saltatory propagation of action *** and not less important,Ols provide trophic support to neurons and ***,Ol metabolism is important for Ol well-being and the proper accomplishment of their functions,and Ol metabolism energetics directly affect the energy metabolism of neighboring neurons.

关键词： metabolism nerves myel.n

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