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Chinese Chemical Letters 2011年第2期22卷 155-158页

作者： meng lin ma Chuan Hong Ren Ya Jing Lv Hua Chen Xian Jun Li Department of Chemistry Xihua UniversityChengdu 610039China Key Lab of Green Chemistry and Technology Ministry of EducationThe Institute of Homogeneous Catalysis Faculty of ChemistrySichuan UniversityChengdu 610064China

Chiral N,N＇-dialkylated cyclohexanediamine derived ligands have been synthesized and used in the asymmetric hydrogenation of aryl *** active alcohols with up to 90%enantiomeric excess were obtained in high yields.

关键词： Chiral diamine Aryl ketone Asymmetric hydrogenation Ruthenium complex

Alkoxy substituted MeO-BIPHEP-type diphosphines ligands for asymmetric hydrogenation of aryl ketones

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Chinese Chemical Letters 2010年第5期21卷 576-579页

作者： meng lin ma Zong Hai Peng Yu Guo Li Chen Hua Chen Xian Jun Li Department of Chemistry Xihua UniversityChengdu 610039China Key Lab of Green Chemistry and Technology Ministry of EducationThe Institute of Homogeneous CatalysisFaculty of ChemistrySichuan UniversityChengdu 610064China

In this paper,a series of optically active MeO-BIPHEP-type ligands,（S）-6,6′-dimethoxy-2,2’-bis（di-p-alkoxyphenylphosphine）- 1,1′-biphenyl were synthesized and used to prepare the ruthenium *** effects of para-substituted were observed,the results showed that the ruthenium catalysts[diphosphine RuCl;diamine]containing both t-Bu and i-Pr substitutions have better activities and enantioselectivities than the non-substituted ruthenium catalysts in the asymmetric hydrogenation of acetophenone.

关键词： Aryl ketone Asymmetric hydrogenation Biaryl phosphines ligands Ruthenium complex

Effect of cholesterol metabolism on hepatolithiasis

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World Journal of Gastroenterology 2025年第1期31卷 157-162页

作者： lin Zheng Zi-Yu Ye Jun-Ji ma Department of Gastroenterology The Second Hospital of Hebei Medical UniversityHebei Key Laboratory of GastroenterologyHebei Institute of GastroenterologyHebei Clinical Research Center for Digestive DiseasesNo.215 Heping West RoadShijiazhuang 050000Hebei ProvinceChina

Surgical intervention is currently the primary treatment for hepatolithiasis;how-ever,some patients still experience residual stones and high recurrence rates after *** metabolism seems to play an important role in hepatoli-thiasis pathogenesis.A high cholesterol diet is one of the significant reasons for the increasing incidence of ***,regular diet and appropriate medical intervention are crucial measures to prevent hepatolithiasis and reduce recurrence rate after *** dietary cholesterol and drugs that increase cholesterol stone solubility are key therapeutic approaches in treating *** article discusses the cholesterol metabolic pathways related to the pathogenesis of hepatolithiasis,as well as food intake and targeted therapeutic drugs.

关键词： Hepatolithiasis Cholesterol metabolism High-fat diet 3-hydroxy-3-methylglutaryl-coenzyme A reductase Interlobular bile duct

我国近年来华留学生教育的发展状况及政策分析

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太原大学学报 2016年第2期17卷 72-75页

作者：蒙玛琳李冲大连理工大学高等教育研究院辽宁大连116023

自2001年我国加入世贸组织并对《服务贸易总协定》做出承诺后,中国为来华留学教育陆续颁布各项政策来优化留学生在中国的教育环境,以期使中国成为真正的留学大国。近年来,来华留学生总人数屡创新高,我们在为来华留学规模得到大力支持而... 详细信息

自2001年我国加入世贸组织并对《服务贸易总协定》做出承诺后,中国为来华留学教育陆续颁布各项政策来优化留学生在中国的教育环境,以期使中国成为真正的留学大国。近年来,来华留学生总人数屡创新高,我们在为来华留学规模得到大力支持而扩大感到高兴的同时,还需注意来华留学生的结构层次的不均衡。因为只有规模与质量并重,中国才能成为留学大国、留学优国。

关键词：来华留学生教育发展政策分析

Locally Enhanced Flow and Electric Fields Through a Tip Effect for Efficient Flow‑Electrode Capacitive Deionization

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Nano-Micro Letters 2025年第2期17卷 1-17页

作者： Ziquan Wang Xiangfeng Chen Yuan Zhang Jie ma Zhiqun lin Amor Abdelkader maria‑magdalena Titirici Libo Deng College of Chemistry and Environmental Engineering Shenzhen UniversityShenzhen 518060People’s Republic of China Research Center for Environmental Functional materials College of Environmental Science and EngineeringTongji University1239 Siping RoadShanghai 200092People’s Republic of China Department of Chemical and Biomolecular Engineering National University of SingaporeSingapore 117585Singapore Department of Engineering Faculty of Science and TechnologyBournemouth UniversityTalbot CampusFern BarrowPooleEngland BH125BBUK Institut de Chimie de Nice UniversitéCôte d’AzurUMR CNRS 727228 Av.Valrose06108 NiceFrance Department of Chemical Engineering Imperial College LondonSouth Kensington CampusExhibition RdLondon SW72AZUK

Low-electrode capacitive deionization(FCDI)is an emerging desalination technology with great potential for removal and/or recycling ions from a range of ***,it still suffers from inefficient charge transfer and ion transport kinetics due to weak turbulence and low electric intensity in flow electrodes,both restricted by the current ***,a new tip-array current collector(designated as T-CC)was developed to replace the conventional planar current collectors,which intensifies both the charge transfer and ion transport *** effects of tip arrays on flow and electric fields were studied by both computational simulations and electrochemical impedance spectroscopy,which revealed the reduction of ion transport barrier,charge transport barrier and internal *** the voltage increased from 1.0 to 1.5 and 2.0 V,the T-CC-based FCDI system(T-FCDI)exhibited average salt removal rates(ASRR)of 0.18,0.50,and 0.89μmol cm^(-2) min^(-1),respectively,which are 1.82,2.65,and 2.48 folds higher than that of the conventional serpentine current collectors,and 1.48,1.67,and 1.49 folds higher than that of the planar current ***,with the solid content in flow electrodes increased from 1 to 5 wt%,the ASRR for T-FCDI increased from 0.29 to 0.50μmol cm^(-2) min^(-1),which are 1.70 and 1.67 folds higher than that of the planar current ***,a salt removal efficiency of 99.89%was achieved with T-FCDI and the charge efficiency remained above 95%after 24 h of operation,thus showing its superior long-term stability.

关键词： Flow-electrode Capacitive deionization Current collector Tip effect Desalination

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头颈部腺样囊性癌的CT和MRI诊断

实用放射学杂志 2008年第6期24卷 741-744页

作者：刘梦雨马林杨波邹智彤解放军总医院放射科解放军总医院放射科北京100853

目的探讨头颈部腺样囊性癌的CT和MRI表现,并评价2种影像检查方法的临床应用价值。方法回顾性分析16例经病理证实的头颈部腺样囊性癌患者的影像资料。结果16例中主要位于上颌窦5例,中耳、口底各3例,鼻咽、腮腺各2例,鼻腔1例。CT表现:受... 详细信息

目的探讨头颈部腺样囊性癌的CT和MRI表现,并评价2种影像检查方法的临床应用价值。方法回顾性分析16例经病理证实的头颈部腺样囊性癌患者的影像资料。结果16例中主要位于上颌窦5例,中耳、口底各3例,鼻咽、腮腺各2例,鼻腔1例。CT表现:受累部位可见形态不规则软组织肿块,边界不清6例,邻近骨有溶骨性骨质破坏3例。MRI表现:病变与肌肉比较,在T1WI肿瘤实质为等信号14例,稍低信号2例,其内有片状短T1信号3例;T2WI表现为等信号6例,稍高、高信号10例,信号不均匀9例。增强扫描病变实质部分明显强化15例,中等程度强化1例。有短T2分隔7例,分隔均不强化。结论CT扫描可清晰显示骨质破坏情况,MRI能够更清晰、准确显示病变侵犯范围。两者结合可为该病的诊断和治疗提供更全面的影像信息。

关键词：腺样囊性癌头颈部肿瘤体层摄影术,X线计算机磁共振成像

CNKSR2 interactome analysis indicates its association with the centrosome/microtubule system

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Neural Regeneration Research 2025年第8期20卷 2420-2432页

作者： lin Yin Yalan Xu Jie Mu Yu Leng Lei ma Yu Zheng Ruizhi Li Yin Wang Peifeng Li Hai Zhu Dong Wang Jing Li Institute for Translational Medicine The Affiliated Hospital of Qingdao UniversityMedical CollegeQingdao UniversityQingdaoShandong ProvinceChina School of Basic Medicine Qingdao UniversityQingdaoShandong ProvinceChina College of Life Sciences and School of PharmacyMedical CollegeQingdao UniversityQingdaoShandong ProvinceChina Department of Urology Qingdao Municipal Hospital Affiliated to Qingdao UniversityQingdaoShandong ProvinceChina

The protein connector enhancer of kinase suppressor of Ras 2(CNKSR2),present in both the postsynaptic density and cytoplasm of neurons,is a scaffolding protein with several protein-binding *** of the CNKSR2 gene have been implicated in neurodevelopmental disorders,particularly intellectual disability,although the precise mechanism involved has not yet been fully *** has demonstrated that CNKSR2 plays a role in facilitating the localization of postsynaptic density protein complexes to the membrane,thereby influencing synaptic signaling and the morphogenesis of dendritic ***,the function of CNKSR2 in the cytoplasm remains to be *** this study,we used immunoprecipitation and high-resolution liquid chromatography-mass spectrometry to identify the interactors of *** a combination of bioinformatic analysis and cytological experiments,we found that the CNKSR2 interactors were significantly enriched in the proteome of the *** also showed that CNKSR2 interacted with the microtubule protein DYNC1H1 and with the centrosome marker *** colocalization analysis confirmed the centrosomal localization of *** we downregulated CNKSR2 expression in mouse neuroblastoma cells(Neuro 2A),we observed significant changes in the expression of numerous centrosomal *** manipulation also affected centrosome-related functions,including cell size and shape,cell proliferation,and ***,we found that CNKSR2 interactors were highly enriched in de novo variants associated with intellectual disability and autism spectrum *** findings establish a connection between CNKSR2 and the centrosome,and offer new insights into the underlying mechanisms of neurodevelopmental disorders.

关键词： autism spectrum disorder centrosome CNKSR2 intellectual disability interactome mass spectrometry microtubule neurodevelopmental disease protein complexes protein-protein interactions

基于网络创业风险防范的大学生网络安全教育研究

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科技创业月刊 2018年第4期31卷 99-102页

作者：王萌林红珍马睿王楠魏慧兰武汉科技大学恒大管理学院湖北武汉430065

新时代大学生创业群体充分利用互联网资源共享、实时交互、个性化与人性化兼具等优势将自己的创新想法付诸实践,体现了网络时代特点。网络平台创业虽形势大好,但其背后暗藏的创业风险不可轻视,其中以网络信息安全、网络犯罪等方面问题... 详细信息

新时代大学生创业群体充分利用互联网资源共享、实时交互、个性化与人性化兼具等优势将自己的创新想法付诸实践,体现了网络时代特点。网络平台创业虽形势大好,但其背后暗藏的创业风险不可轻视,其中以网络信息安全、网络犯罪等方面问题尤为突出。以网络安全教育为立足点,通过对网络创业现状与前景、具体安全风险及高校网络创业教育的不足进行调研与分析,直攫网络创业"痛点",并归结出一套切实可行的以高校、政府构成的创业生态保护链为核心为大学生网络创业保驾护航的风险防范对策教育模式。

关键词：网络创业风险网络安全教育网络创业教育模式

A general strategy for the reliable joining of Al/Ti dissimilar alloys via ultrasonic assisted friction stir welding

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Journal of materials Science & Technology 2019年第1期35卷 94-99页

作者： Zhongwei ma Yanye Jin Shude Ji Xiangchen meng lin ma Qinghua Li School of Aerospace Engineering Shenyang Aerospace University

Ultrasonic assisted friction stir welding(UaFSW) was used to join 6061-T6 aluminum and Ti6Al4 V alloys.A small plunge depth endowed with the low heat input was used and the sound joints without obvious thickness reduction were achieved. A diffusion-type bonding without the intermetallic compounds layer was observed at the joint interface. The ultrasonic improved the diffusion thickness and decreased the average size of grains and titanium alloy fragments. A hook-like structure was formed at the bottom interface of the UaFSW joint, which improved the bonding length and the mechanical interlocking. The microhardness of the stir zone was increased because of the further grain refinement induced by ultrasonic. The maximum tensile strength of the UaFSW joint was 236 MPa, which reached 85% of the base6061-T6 alloy.

关键词： Friction stir welding Ultrasonic Aluminum/titanium alloys Microstructure Mechanical properties

Boosting bidirectional sulfur conversion enabled by introducing boron-doped atoms and phosphorus vacancies in Ni2P for lithium-sulfur batteries

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Journal of Energy Chemistry 2025年第1期100卷 760-769页

作者： lin Peng Yu Bai Hang Li Meixiu Qu Zhenhua Wang Kening Sun Advanced Research Institute of Multidisciplinary Science Beijing Institute of Technology Beijing Key Laboratory of Chemical Power Source and Green Catalysis School of Chemistry and Chemical Engineering Beijing Institute of Technology

Lithium-sulfur （Li-S） batteries have gained great attention due to the high theoretical energy density and low cost,yet their further commercialization has been obstructed by the notorious shuttle effect and sluggish redox ***,we supply a strategy to optimize the electron structure of Ni2P by concurrently introducing B-doped atoms and P vacancies in Ni2P （Vp-B-Ni2P）,thereby enhancing the bidirectional sulfur *** study indicates that the simultaneous introduction of B-doped atoms and P vacancies in Ni2P causes the redistribution of electron around Ni atoms,bringing about the upward shift of d-band center of Ni atoms and effective d-p orbital hybridization between Ni atoms and sulfur species,thus strengthening the chemical anchoring for lithium polysulfides （LiPSs） as well as expediting the bidirectional conversion kinetics of sulfur ***,theoretical calculations reveal that the incorporation of B-doped atoms and P vacancies in Ni2P selectively promotes Li2S dissolution and nucleation ***,the Li-S batteries with Vp-B-Ni2P-separators present outstanding rate ability of 777 m A h g-1at 5 C and high areal capacity of 8.03 ma h cm-2under E/S of 5μL mg-1and sulfur loading of 7.20 mg *** work elucidates that introducing heteroatom and vacancy in metal phosphide collaboratively regulates the electron structure to accelerate bidirectional sulfur conversion.

关键词： Lithium sulfur batteries