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A Metabolic-associated Nomogram Predicts Recurrence Survival of Thyroid Cancer

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Current Medical Science 2021年第5期41卷 1004-1011页

作者： Zi-han XI Xian-xiong MA Heng-yu CHEN yuan-hang YU Lei LI Tao HUANG department of Breast and Thyroid Surgery Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Depcirtment of Gastrointestinal Surgery Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Department of Pancreatic Surgery Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China NHC Key Laboratory of Hormones and Development Tianjin Institute of EndocrinologyTianjin Medical University Chu Hsien-I Memorial HospitalTianjin 300134China

Objective:Various studies have suggested that metabolic genes play a significant role in papillary thyroid cancer(PTC).The current study aimed to identify a metabolic signature related biomarker to predict the prognosis of patients with ***:We conducted a comprehensive analysis on the data obtained from the Cancer Genome Atlas(TCGA)*** correlation between survival result and metabolic genes was evaluated based on the univariate Cox analyses,least absolute shrinkage and selection operator(LASSO)and multivariate Cox *** performance of a 7-gene signature was assessed according to Kaplan-Meier and receiver operating characteristic(ROC)*** Cox regression analysis was adopted to unearth clinical factors related to the recurrence free survival(RFS)of patients with ***,a prognostic nomogram was developed based on risk score,cancer status and cancer width to improve the prediction for RFS of PTC ***:Seven metabolic genes were used to establish the prognostic *** ROC curve and C-index exhibited high value in training,testing and the whole TCGA *** established nomogram,incorporating the 7-metabolic gene signature and clinical factors,was able to predict the RFS with high *** 7-metabolic gene signature-based nomogram had a good performance to predict the RFS of patients with ***:Our study identified a 7-metabolic gene signature and established a prognostic nomogram,which were useful in predicting the RPS of PTC.

关键词： signature metabolism papillary thyroid cancer recurrence free survival nomogram

Enhanced effects of IL-6/IL-2 fusion gene trans-duction in inhibition of B16 cell turnorigenicity and metastatic potential

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中国实验血液学杂志 1997年第3期5卷 306-307页

作者： Xiao-Dan Yu, Pei-hsien Tang, Chun-Hua Zhao, Ming-Wei Zhang, Shan-Yun Peng, yuan-Lin Liu, Ning Mao Department of Cell Biology, Beijing Institute of Basic Medical Sciences, Beijing 100850

In order to investigate the effects of cytokine fusedgene transfection on tumor cell modification, threeretroviral vectors for human interleukin 6 (IL-6),interleukin 2 (IL-2) and, IL-6/IL-2 fusion gene wereconstructed. The retroviral vectors were introduced intomurine B16 melanoma cell line respectively and theeffects of single or fused cytokine gene on tumor cellbiology in vitro and in vivo were examined. In vivo, thethree cytokine gene-modified B16 cells all showeddecreased tumorigenicity and metastatic potentials,however, the reduction in tumorigenicity and

关键词： metastatic cytokine interleukin transfection melanoma metastasis fused laminin antitumor protective

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墨子推理方法对于孟子的影响

四川大学学报（哲学社会科学版） 2017年第5期 41-48页

作者：李贤中台湾大学哲学系

墨子受儒学影响而非儒,孟子评击墨子,然而墨子推理方法对孟子有诸多影响,如三表法、"辟式"、"援式"、"推式"与归谬法等。从推理内容来看,墨子为求兴天下之利以说服君王,注重社会公义;孟子将说服术运用于说服君王行仁政、王道,注重伦理... 详细信息

墨子受儒学影响而非儒,孟子评击墨子,然而墨子推理方法对孟子有诸多影响,如三表法、"辟式"、"援式"、"推式"与归谬法等。从推理内容来看,墨子为求兴天下之利以说服君王,注重社会公义;孟子将说服术运用于说服君王行仁政、王道,注重伦理关系。从推理特征看,墨子的推理方法呈现推论的形式与内容密切相关,论述观点也与情境构作相配合,此对孟子有极大的影响。

关键词：墨子孟子推理方法三表法辟式援式推式归谬法

Advanced Functional Polymeric Materials: Synthesis and Optoelectronic Applications

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Advanced Functional Polymeric Materials: Synthesis and Optoe...

Numerical Study of Blast Effects impacting on the Vehicles in Tunnel with Dynamic Mesh Model

第二届海峡两岸功能材料科技与产业峰会（2015）

作者： CHOU-YI TSAI PO-I WANG CHUN-hsien WU QIANG ZHANG YING-CHI HUANG WEI-TING WANG YIAN TAI JUN-yuan JENG TZUNG-FANG GUO DER-JANG LIAW “National Taiwan University of Science and Technology” “National Cheng Kung University”

Advanced functional polymeric materials such as polyimides(PIs),polyamides(PAs),conjugated polymers and polynorbornenes(PNBs)were successfully synthesized through various polymerization methods including low temperature polycondensation,Suzuki coupling and ring-opening metathesis polymerization(ROMP).PIs derived from different architecture designs revealed unique physical-mechanical,electrical and chemical

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Numerical Study of Blast Effects impacting on the Vehicles i...

Retrotracheal thymoma masquerading as esophageal submucosal tumor

The 4th Across-strait Workshop on Shock Wave/Vortex Interaction

作者： Chang-hsien Tai Jyh-tong Teng Shi-wei Lo Uzu-kuei Hsu Department of Vehicle Engineering Pingtung University of Science and Technology Department of Mechanical Engineering Chung Yuan Christian University

The blast effects caused by the explosion generate serious damage during propagation and interaction.A great injuries and deaths incident incurred because of explosion in petrochemical industry,firecracker factory and car-mounted gas,*** the world in recent ***, the 911 crashes in 2001,Bali’s series of explosion in 2002,and Benazir Bhutto assassinated in

关键词： blast wave CFD dynamic mesh overpressure reflection tunnel vehicles

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World Journal of Gastroenterology 2005年第20期11卷 3165-3166页

作者： Sheung-Fat Ko yuan-Hsiung Tsai Hsuan-Ying Huang Shu-Hang Ng Fu-Ming Fang Yeh Tang Ming-Tse Sung Ming-Jang Hsieh Departments of Radiology Chang Gung University Chang Gung Memorial Hospital at Kaohsiung Kaohsiung Hsien Taiwan China Departments of Pathology Chang Gung University Chang Gung Memorial Hospital at KaohsiungKaohsiung Hsien Taiwan China Departments of Oncology Chang Gung University Chang Gung Memorial Hospital at Kaohsiung Kaohsiung Hsien Taiwan China Departments of Thoracic Surgery Chang Gung Memorial Hospital at Kaohsiung Kaohsiung Hsien Taiwan China

A 42-year-old man presented with a two-year history of progressive dysphagia and hoarseness. Esophagogram and endoscopy revealed submucosal mass effect on the upper esophagus. Computed tomography and magnetic resonance imaging revealed an elongated mass in the retrotracheal region of the lower neck with extension to the posterior mediastinum. Partial tumor resection and histopathological evaluation revealed a WHO type B2 thymoma. Adjuvant radiation and chemotherapy were subsequently administered resulting in complete tumor regression. To our knowledge, this is the first report of ectopic retrotracheal thymoma with clinical and imaging manifestations mimicking those for esophageal submucosal tumor.

关键词： Dysphagia Hoarseness

Hybrid Multi-Object Optimization Method for Tapping Center Machines

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Intelligent Automation & Soft Computing 2023年第4期 23-38页

作者： Ping-Yueh Chang Fu-I Chou Po-yuan Yang Shao-hsien Chen Department of Electrical Engineering National Kaohsiung University of Science and TechnologyKaohsiung807China Taiwan Department of Intelligent Robotics National Pingtung UniversityPingtung900China Taiwan Graduate Institute of Precision Manufacturing National Chin-Yi University of TechnologyTaichung411China Taiwan

This paper proposes a hybrid multi-object optimization method integrating a uniform design,an adaptive network-based fuzzy inference system(ANFIS),and a multi-objective particle swarm optimizer(MOPSO)to optimize the rigid tapping parameters and minimize the synchronization errors and cycle times of computer numerical control(CNC)***,rigid tapping parameters and uniform(including 41-level and 19-level)layouts were adopted to collect representative data for ***,ANFIS was used to build the model for the collected 41-level and 19-level uniform layout experiment *** tapping center machines,the synchronization errors and cycle times are important consid-erations,so these two objects were used to build the ANFIS ***,a MOPSO algorithm was used to search for the optimal parameter combinations for the two ANFIS models *** experimental results showed that the proposed method obtains suitable parameter values and optimal parameter combinations compared with the nonsystematic ***,the optimal parameter combination was used to optimize existing CNC tools during the commissioning *** the proportional and integral gains of the spindle could improve resistance to deformation during rigid *** posi-tion gain and prefeedback coefﬁcient can reduce the synchronization errors signiﬁcantly,and the acceleration and deceleration times of the spindle affect both the machining time and synchronization *** proposed method can quickly and accurately minimize synchronization errors from 107 to 19.5 pulses as well as the processing time from 3,600 to 3,248 ms;it can also shorten the machining time signiﬁcantly and reduce simultaneous errors to improve tapping yield,there-by helping factories achieve carbon reduction.

关键词： Tapping center machine uniform design adaptive network-based fuzzy inference system(ANFIS) multi-objective particle swarm optimizer

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小额信贷之违约概率模型：特别考虑异质性

浙江大学学报（人文社会科学版） 2008年第2期38卷 179-188页

作者：杨显爵林左裕陈震远陈震武陈宗豪高雄第一科技大学风险管理与保险系中国台湾省高雄市政治大学地政学系中国台湾省台北市永达技术学院信息管理系中国台湾省屏东县树德科技大学运筹管理系中国台湾省高雄市明道大学企业管理学系中国台湾省彰化县

在新巴塞尔资本协议(New Basel Capital Accord)对金融全球化的冲击及金融机构改善资产质量及合并政策的影响下,我国台湾地区金融业进入激烈合并竞争的时代。许多银行颇受降低逾放比率及增加净值报酬率与资产报酬率两难之困扰。消费性... 详细信息

在新巴塞尔资本协议(New Basel Capital Accord)对金融全球化的冲击及金融机构改善资产质量及合并政策的影响下,我国台湾地区金融业进入激烈合并竞争的时代。许多银行颇受降低逾放比率及增加净值报酬率与资产报酬率两难之困扰。消费性信用贷款产品利差大、风险分散,是金融机构授信经营极重要的产品。实证结果显示,采用世代研究(cohort study)建立之模型对样本数据之拟合程度较个案对照研究法(casecontrol study)的解释变异量为佳,且较符合新巴塞尔资本协议规定及科学程序。虽然Logistic回归模型在建立逾期概率模型上广泛地被使用,但要求存在于同构型的变异数Var=np(1-p)假设上,且在数据分析上常因为出现变异数之异质性问题,故可采用调整变异数异质性之方法。

关键词：消费者小额贷款世代研究法个案对照研究法逾期放款过度离散

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梳理白先勇文艺的出版与研究

华文文学 2016年第4期 74-80页

作者：庄园汕头大学台港及海外华文文学研究中心澳门大学

本文从编辑职业和研究前期准备的角度,把白先勇文艺的传播与接受梳理了几个板块,包括白先勇作品的出版——中文出版、英文出版、其他语种出版、《孽子》的出版情况;其中中文出版最大一块是在台湾,其次是中国大陆、香港、新加坡等。还有... 详细信息

本文从编辑职业和研究前期准备的角度,把白先勇文艺的传播与接受梳理了几个板块,包括白先勇作品的出版——中文出版、英文出版、其他语种出版、《孽子》的出版情况;其中中文出版最大一块是在台湾,其次是中国大陆、香港、新加坡等。还有舞台剧和影视剧改编、推广昆曲、演讲会及获奖(荣誉)、研究白先勇的论著、传记与单篇论文的基本情况等。

关键词：梳理白先勇出版与研究