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On REDUCTIOn OF MULTICOMPOnEnT COSMOLOGY TO TODA LATTICE

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Chinese Physics Letters 1990年第3期7卷 97-100页

作者： v.D.Ivashchuk v.n.melnikov USSR State Committee for Standards 9 Leninsky prospectMoscow 117049USSR

We prove that Gibbons-Maeda reduction of two-component cosmology to the Toda lattice can not be generalyzed for n-component case.

关键词： MULTI lattice component

On Charged Black Hole in Multidimensional Theory with Ricci-Flat Internal Spaces

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Chinese Physics Letters 1991年第9期8卷 439-441页

作者： S.B.Fadeev v.D.Ivashchuk v.n.melnikov USSR State Committee for Standards 9 Leninski Prospect117049MoscowUSSR

A generalization of the Reissner-nordstrom solution for the case of n internal Ricci-flat spaces is obtained.

关键词： Ricci generalization Reissner

Dendritic spine degeneration:a primary mechanism in the aging process

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neural Regeneration Research 2025年第6期20卷 1696-1698页

作者： Gonzalo Flores Leonardo Aguilar-Hernández Fernado García-Dolores Humberto nicolini Andrea Judith vázquez-Hernández Hiram Tendilla-Beltrán Instituto de Fisiología Benemérita Universidad Autónoma de Puebla(BUAP)PueblaMexico Instituto de Ciencias Forenses(InCIFO) Tribunal Superior de Justicia de la Ciudad de México(TSJCDMX).Mexico CityMexico Instituto nacional de Medicina Genómica(InMEGEn) Mexico CityMexico

Recent reports suggest that aging is not solely a physiological process in liv.n. beings;instead, it should be considered a pathological process or disease(Amorim et al., 2022). Consequently, this process involves a wide range of factors, spanning from genetic to environmental factors, and ev.n.includes the gut microbiome(GM)(Mayer et al., 2022). All these processes coincide at some point in the inflammatory process, oxidative stress, and apoptosis, at different degrees in various organs and systems that constitute a liv.n. organism(Mayer et al., 2022;AguilarHernández et al., 2023).

关键词： aging process stress

Analysis of non-ionized substance losses in experiments on plasma mass separation

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Plasma Science and Technology 2022年第8期24卷 124-129页

作者： R A USMAnOv.n.n AnTOnOv A v GAvRIKOv G D LIZIAKIn A D melnikov A P OILER v P SMIRnOv R A TIMIRKHAnOv L S vOLKOv.n.A vOROnA Laboratory of Electrophysical and Plasma Devices Joint Institute for High TemperatureMoscow 125412Russia

Plasma mass separation requires a lot of diagnostic techniques that not only demonstrate the separation effect but also show the efficiency of the *** the test experiments,plasma flux to be separated may contain neutral particles that avoid the separation process due to their insensitivity to electromagnetic *** present the diagnostics of the lost substance in experiments on plasma mass *** obtained data of the diagnostics helps determine the law of particle evaporation from the plasma *** show that neutral flux is unable to distort the result of separation *** presented approach can be used in experiments aimed at enhancing the separation effect and achiev.n. target productivity for industry applications.

关键词： plasma mass separation plasma diagnostics lead silver film deposition

MODELInG THE KnOWLEDGE CREATIOn PROCESS OF GRADUATE RESEARCH

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Journal of Systems Science and Systems Engineering 2018年第6期27卷 790-809页

作者： J. Sun J. Tian v.n. Huynh Y. nakamori School of Knowledge Science Japan Advanced lnstitute of Science and Technology lshikawa Japan School of Computer Science and Technology Wuhan University of Technology Wuhan China

Graduate students who are beginning academic research want to learn how to create and verify new knowledge in their research. Their supervisors, on the other hand, are seeking appropriate research environments including effective research guidance methods. In order to meet these demands, this paper proposes a knowledge creation model that supports the objectives of both graduate students and their supervisors. This is an academic knowledge creation model for individuals supported by a group and its origin can be traced back to a famous organizational knowledge creation model. Since this type of model is constructed from empirical knowledge, it is not easy to prove its objective significance. But, this paper tries to show the effectiv.n.ss of the proposed model as an initial stage of model validation based on a questionnaire survey of students in a graduate school in China.

关键词： Knowledge creation model graduate students research ability research environment

Phase-matched third-harmonic generation via doubly resonant optical surface modes in 1D photonic crystals

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Light(Science & Applications) 2016年第1期5卷 424-429页

作者： valery n Konopsky Elena v Alieva Sergey Yu Alyatkin Alexey A melnikov Sergey v Chekalin vladimir M Agranovich Institute of Spectroscopy Fizicheskaya5TroitskMoscow 142190Russia Moscow Institute of Physics and Technology Institutskiy per.9Dolgoprudny 141700Russia

Efficient nonlinear conversion requires that interacting optical waves maintain a consistent phase relationship when traveling in a medium despite its *** phase-matching,which is often used to compensate for the dispersion,is not applicable to optically isotropic nonlinear ***,we present a one-dimensional photonic crystal structure that allows the propagation of optical surface waves,both at the fundamental and third-harmonic frequencies,as an efficient medium for phasematched third-harmonic generation.A unique adv.n.age of this structure is that the effective refractive indices for the surface waves are similar to the refractive index of air at both *** allows phase-matching between the first and third harmonics,and a visible collinear beam of the third harmonic is produced at the prism-coupled ***,these optical surface waves propagate over long distances ev.n.if a lossy nonlinear nanofilm is deposited onto the photonic crystal *** provide experimental results for third-harmonic generation at a wavelength of 410 nm for a bare dielectric Ta2O5/SiO2 multilayer structure and for the same structure coated with a 15-nm GaAs film.

关键词： nonlinear optics optical surface waves photonic crystals

Application of integrated simulation environment SIEMnED to the analysis of the MEPHIST-0 tokamak operation

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Plasma Science and Technology 2023年第3期25卷 222-233页

作者： D Yu SYCHUGOv S Yu SOLOvIEv A S ZHILKIn A v melnikov S A KRAT Faculty of Computational Mathematics and Cybernetics Lomonosov Moscow State University national Research Centre Kurchatov Institute national Research nuclear University Moscow Engineering Physics Institute national University Moscow Institute of Physics and Technology

This paper presents the results of numerical simulation of plasma equilibrium and stability in the MEPHIST-0 tokamak with SIEMnED software and comparison of simulation results with *** determined characteristics of the vacuum chamber show that it significantly affects the entire *** various scenarios of the inductor operation,a comparison of experimental data and simulated currents and magnetic fields induced in the chamber was carried *** steady-state tokamak operation,a numerical study of equilibrium plasma configurations was carried out depending on the currents in the poloidal magnetic field coils and plasma *** vertical plasma instability was *** limiting values of plasma ellipticity prev.n.ing the vertical plasma instability were numerically *** simulations show that plasma equilibrium is supported by induced *** was shown numerically that magnetic configuration with‘zero of higher order’were obtained before the plasma shot,suggesting consistency between the simulation results and observations.

关键词： mathematical modelling tokamak installation MEPHIST-0

Impacts of PI3K/protein kinase B pathway activation in reactive astrocytes: from detrimental effects to protective functions

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neural Regeneration Research 2025年第4期20卷 1031-1041页

作者： Ramón Pérez-núñez María Fernanda González Ana María Avalos Lisette Leyton Cellular Communication Laboratory Programa de Biología Celular y MolecularCenter for Studies on ExerciseMetabolism and Cancer(CEMC)Instituto de Ciencias Biomédicas(ICBM)Facultad de MedicinaUniversidad de ChileSantiagoChile Adv.n.ed Center for Chronic Diseases(ACCDiS) Faculty of Chemical and Pharmaceutical Sciences&Faculty of MedicineUniversidad de ChileSantiagoChile Instituto de Ciencias Biomédicas Facultad de Ciencias de la SaludUniversidad Autónoma de ChileSantiagoChile

Astrocytes are the most abundant type of glial cell in the central nervous *** injury and inflammation,astrocytes become reactive and undergo morphological and functional *** on their phenotypic classification as A1 or A2,reactive astrocytes contribute to both neurotoxic and neuroprotective responses,***,this binary classification does not fully capture the diversity of astrocyte responses observed across different diseases and *** analysis has revealed that reactive astrocytes have a complex landscape of gene expression profiles,which emphasizes the heterogeneous nature of their *** actively participate in regulating central nervous system inflammation by interacting with microglia and other cell types,releasing cytokines,and influencing the immune *** phosphoinositide 3-kinase(PI3K)/protein kinase B(AKT)signaling pathway is a central player in astrocyte reactivity and impacts various aspects of astrocyte behavior,as evidenced by in silico,in vitro,and in vivo *** astrocytes,inflammatory cues trigger a cascade of molecular ev.n.s,where nuclear factor-κB serves as a central mediator of the pro-inflammatory ***,we review the heterogeneity of reactive astrocytes and the molecular mechanisms underlying their *** highlight the involvement of various signaling pathways that regulate astrocyte reactivity,including the PI3K/AKT/mammalian target of rapamycin(mTOR),αvβ3 integrin/PI3K/AKT/connexin 43,and notch/PI3K/AKT *** targeting the inactivation of the PI3K/AKT cellular signaling pathway to control reactive astrocytes and prev.n. central nervous system damage,evidence suggests that activating this pathway could also yield beneficial *** dual function of the PI3K/AKT pathway underscores its complexity in astrocyte reactivity and brain function *** review emphasizes the importance of employing astrocyte-exclusive models to underst

关键词： inflammation integrins neuroprotective neurotoxic phosphatidylinositol 3-kinase reactive astrocytes signal transduction Thy-1(CD90)

Influence of frost weathering on the recession of surfaces of technogenic landforms in Yakutia

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Research in Cold and Arid Regions 2019年第4期11卷 257-266页

作者： Andrey E.melnikov nikolay n.Grib melnikov Permafrost Institute of the Siberian Branch of the Russian Academy of Sciences Yakutsk 677010Russia Technical Institute(branch)of M.K.Ammosov.n.rth-eastern Federal University Neryungri 678960Russia

The article assesses the influence of permafrost weathering on the rate of destruction of technogenic land forms,as exhibit ed on as illustrated by the railway embankment of the Amur Yakut mainline in the Sakha Republic(Yakutia).Studies were carried out on a railway section more than 375 km *** subsidence rate of the embankment slopes and structur al excavations was determined using laboratory methods that simulate various mechanisms of temperature(with a transi tion through 0℃)impact on *** the first time,a quantitative assessment of the influence of cryogenic weathering on the stability of the railway in the region belonging to the northern building climatic zone is *** the territory un der consideration,embankment rocks were experimentally determined to undergo more than 100 freezing and thawing cy cles during a *** the existing climatic conditions,cryogenic weathering actively affects the embankment of the railway to a depth of 30 *** of the embankment deformations detected during field observations are due to defects in the integrity of this particular *** size of the disintegrating layer of particular types of rock comprising the rail way embankment has been established as reaching 10 cm per *** 5 years following the formation of embankments comprising the upper structure of the railroad tracks,the physical and mechanical properties of rocks,which initially had a tensile strength for uniaxial compression in the range of 40 70 MPa,were reduced by more than 50%.According to the authors,the establishment of regional cryohypergenesis features is universal in nature and can be applied to solv.n. a wide range of tasks related to the assessment and prediction of the degree of cryogenic transformation of rocks hav.n. different structural properties.

关键词： cryogenic weathering embankment railway subsidence rate Republic of Sakha Yakutia