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人工关节感染一期翻修的生存率和失败原因:一项荟萃分析

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临床骨科杂志 2024年第5期 639-639页

作者： PEDDADA K V WELCOME B M parker M C 胡孔足

为研究人工关节感染一期翻修术的生存率和失败原因，作者使用“一期翻修”“假体交换”“假体周围感染”“PJI”“一期”等词进行检索后的病例荟萃分析。共检索出24项研究，包括2 062例全髋置换术后假体周围感染一期翻修和147例全膝置...

为研究人工关节感染一期翻修术的生存率和失败原因，作者使用“一期翻修”“假体交换”“假体周围感染”“PJI”“一期”等词进行检索后的病例荟萃分析。共检索出24项研究，包括2 062例全髋置换术后假体周围感染一期翻修和147例全膝置换术后假体周围感染一期翻修患者。男性占55%，平均年龄66.3岁，随访69.8个月。所有原因中:再翻修率为全髋置换11.1%、全膝置换11.8%，其中感染率全髋置换5.5%、全膝置换3.3%，无菌性松动为全髋置换3%、全膝置换8.8%。

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Photoprotective Ability of Colored Iron Oxides in Tinted Sunscreens against Ultraviolet, Visible Light and Near-Infrared Radiation

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Optics and Photonics Journal 2023年第8期13卷 199-208页

作者： Yohei Tanaka Richard parker Amaryllis Aganahi Clinica Tanaka Plastic Reconstructive Surgery and Anti-Aging Center Matsumoto Japan RATIONALE Kyneton Victoria Australia

Solar-induced skin damage continues to pose a problem to human health worldwide, despite the widespread recommendation and use of sunscreens. We have previously reported that solar visible light and near-infrared also contribute to skin damage and photoageing. Most commonly recommended sunscreens are only effective throughout the UV spectrum, offering no protection from visible light and near-infrared. To evaluate the enhanced solar-spectrum blocking ability of iron oxides, a double-beam spectrophotometer was used to optically measure the transmission spectra. The spectrophotometer deploys a unique, single monochromatic design to detect wavelength penetration in the range of 240 to 2600 nm. The sample without iron oxide (control) blocked over 80% of ultraviolet-C and ultraviolet-B but did not block ultraviolet-A, visible light, or near-infrared wavelengths. The samples with yellow, and red iron oxide blocked over 90% ultraviolet, but did not block visible light and near-infrared effectively. The sample with black iron oxide blocked visible light, and near-infrared effectively compared with other samples with yellow, blue, and red iron oxide. The sample with red and black iron oxides, and the sample with yellow, blue, red, and black iron oxides blocked ultraviolet through to near-infrared. It can be concluded that dark colored iron oxide combinations are effective at blocking from ultraviolet through to visible light and near-infrared radiation. The results of this study may also suggest that biological colour of human skin and subcutaneous tissues are conserved for comprehensive photoprotection.

关键词： Anti-Photoageing Photoimmunosuppression Photoprotection Sunscreen Ultraviolet Visible Light Near-Infrared

Divorce,It Seems,Can Make You Ill

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科技英语学习 2009年第9期 25-27页

作者： Tara parker-Pope 丁立福

在最近的一项研究中，科学家们试图探索离异、丧偶、及再婚对当事人的健康状况有何影响。该研究虽不能说明婚姻中的不幸是健康问题的诱因，但却揭示出了这两者之间的关联，并从人体细胞层面的变化对上述关联加以阐释。那么，这是否意味... 详细信息

在最近的一项研究中，科学家们试图探索离异、丧偶、及再婚对当事人的健康状况有何影响。该研究虽不能说明婚姻中的不幸是健康问题的诱因，但却揭示出了这两者之间的关联，并从人体细胞层面的变化对上述关联加以阐释。那么，这是否意味着夫妻双方出于对身体健康的考虑，就应该继续维系不美满的婚姻呢？请您阅读本文，一探究竟。

关键词：婚姻健康问题科学家研究

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GIS的“系统”

国外测绘 1994年第3期 32-36,42页

作者： parker,D 赵波

单个ＧＩＳ软件包很难满足某一用户的所有要求，通常要有几个软件包才能满足用户需要由于用户期望不断增加，越来越多的机构需要一个适应范围较大的ＧＩＳ分析软件包，空间数据采集和其它方面必须要考虑数据的瘘容性和数据和长期可用性... 详细信息

单个ＧＩＳ软件包很难满足某一用户的所有要求，通常要有几个软件包才能满足用户需要由于用户期望不断增加，越来越多的机构需要一个适应范围较大的ＧＩＳ分析软件包，空间数据采集和其它方面必须要考虑数据的瘘容性和数据和长期可用性，用使用户可以从各种分析软件中获盗，目前已有一些可以使用的系统。本文描述建立一个适应于所有数据并独立于任何一种应用软件的地理信息系统的方法这种方法允许在不同应用软件包间交换数据。

关键词：地理信息系统软件数据结构

Roles of Arabidopsis Patatin-Related Phospholipases A in Root Development Are Related to Auxin Responses and Phosphate Deficiency

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Molecular Plant 2010年第3期3卷 524-538页

作者： Steffen Rietz Georgi Dermendjiev Esther Oppermann Fikadu Getah Tafesse Yunus Effendi Andre Holk Jane E. parker Markus Teige Gunther F.E. Scherer Max Planck Institute for Plant Breeding Research Department of Plant Microbe Interactions Carl von Linne Weg 10 D-50829 Cologne Germany Leibniz University Hannover Molecular Developmental Physiology Herrenhauser Str. 2 D-30419 Hannover Germany University of Vienna MFPL Department of Biochemistry Dr. Bohrgasse 9 A-1030 Wien Austria Present address: University of Utrecht Department of Membrane Enzymology Inst. Biomembranes Padualaan 8 NL 3584 CH Utrecht. The Netherlands

Phospholipase A enzymes cleave phospho- and galactolipids to generate free fatty acids and lysolipids that function in animal and plant hormone signaling. Here, we describe three Arabidopsis patatin-related phospholipase A （pPLA） genes AtPLAIVA, AtPLAIVB, and AtPLAIVC and their corresponding proteins. Loss-of-function mutants reveal roles for these pPLAs in roots during normal development and under phosphate deprivation. AtPLAIVA is expressed strongly and exclusively in roots and AtplalVA-null mutants have reduced lateral root development, characteristic of an impaired auxin response. By contrast, AtPLAIVB is expressed weakly in roots, cotyledons, and leaves but is transcriptionally induced by auxin, although AtplalVB mutants develop normally. AtPLAIVC is expressed in the floral gynaecium and is induced by abscisic acid （ABA） or phosphate deficiency in roots. While an AtplalVC-1 loss-of-function mutant displays ABA respon- siveness, it exhibits an impaired response to phosphate deficiency during root development. Recombinant AtPLA proteins hydrolyze preferentially galactolipids and, less efficiently, phospholipids, although these enzymes are not localized in chloroplasts. We find that AtPLAIVA and AtPLAIVB are phosphorylated by calcium-dependent protein kinases in vitro and this enhances their activities on phosphatidylcholine but not on phosphatidylglycerol. Taken together, the data reveal novel functions of pPLAs in root development with individual roles at the interface between phosphate deficiency and auxin signaling.

关键词： Abiotic/environmental stress hormonal regulation protein phosphorylation/dephosphorylation signaltransduction gene regulation Arabidopsis.

Recovery rates of combination antibiotic therapy using in vitro microdialysis simulating in vivo conditions

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Journal of Pharmaceutical Analysis 2018年第6期8卷 407-412页

作者： Jayesh A.Dhanani Suzanne L.parker Jeffrey Lipman Steven C.Wallis Jeremy Cohen John Fraser Adrian Barnett Michelle Chew Jason A.Roberts Burns Trauma and Critical Care Research Centre The University of Queensland UQ Centre for Clinical Research Department of Intensive Care Medicine Royal Brisbane & Women's Hospital Faculty of Health Queensland University of Technology Critical Care Research Group The University of Queensland Institute of Health and Biomedical Innovation & School of Public Health and Social Work Queensland University of Technology Department of Anaesthesiology and Intensive Care and Department of Medical and Health Sciences Link?ping University School of Pharmacy The University of Queensland Department of Pharmacy Royal Brisbane & Women's Hospital

Microdialysis is a technique used to measure the unbound antibiotic concentration in the interstitial spaces, the target site of action. In vitro recovery studies are essential to calibrating the microdialysis system for in vivo studies. The effect of a combination of antibiotics on recovery into microdialysate requires investigation. In vitro microdialysis recovery studies were conducted on a combination of vancomycin and tobramycin, in a simulated in vivo model. Comparison was made between recoveries for three different concentrations and three different perfusate flow rates. The overall relative recovery for vancomycin was lower than that of tobramycin. For tobramycin, a concentration of 20μg/mL and flow rate of 1.0μL/min had the best recovery. A concentration of 5.0μg/mL and flow rate of 1.0μL/min yielded maximal recovery for vancomycin. Large molecular size and higher protein binding resulted in lower relative recoveries for vancomycin. Perfusate flow rates and drug concentrations affected the relative recovery when a combination of vancomycin and tobramycin was tested. Low perfusate flow rates were associated with higher recovery rates. For combination antibiotic measurement which includes agents that are highly protein bound, in vitro studies performed prior to in vivo studies may ensure the reliable measurement of unbound concentrations.

关键词： Microdialysis Combination antibiotic therapy Relative recovery rate Pharmacokinetics Anti-infectives Protein binding

从英语母语者角度分析英译汉交替传译中的产出问题——以人性化人工智能与COVID-19模拟会议为例

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从英语母语者角度分析英译汉交替传译中的产出问题——以人性化人...

作者： parker Walker 上海外国语大学

学位级别：硕士

目前大量中英口译研究是从中文为母语的口译员的视角出发,从英语为母语的口译员的视角进行的英译汉研究较为少见。在“人工智能与新冠疫情”主题的模拟会议中,笔者作为英语为母语、中文为第二语言的译员,进行了英译中交替传译。基于对... 详细信息

目前大量中英口译研究是从中文为母语的口译员的视角出发,从英语为母语的口译员的视角进行的英译汉研究较为少见。在“人工智能与新冠疫情”主题的模拟会议中,笔者作为英语为母语、中文为第二语言的译员,进行了英译中交替传译。基于对译文转写稿的考察,笔者发现自身的译语产出存在较大问题。本论文从笔者在模拟会议英译中产出中存在的问题入手,试图从英语为母语译员角度出发,分析他们在口译过程中遇到的困难和问题,从中总结和探讨问题类型、根本原因和解决方案。笔者将自己的中文译语产出错误分为与语言形式和内容分别相关的两大类,并在此框架下进行了细分、展示和分析。在对上述问题进行分类展示和分析以后,本文对于造成产出问题的原因进行了分析,发现由于否定性评价理论中的评价者效应,口译场景中的心理压力会导致认知资源欠缺,使译者原本较为熟练的中文产出发生变形,出现语言形式和内容上的各种错误。而且绝大多数错误并非由于英语母语干扰而产生,而是由于心理压力导致的无规律的中文语内表达错误。最后,本文提出了相应的改进策略。

关键词：英汉口译交传口译英语为母语口译员中文产出语错误语内问题否定性评价理论

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异重流卷吸系数和运行距离的初步探讨

泥沙研究 2015年第6期40卷 6-13页

作者：王睿禹 Garcia Marcelo parker Gary 美国伊利诺伊大学周文德实验室 urbanail61801

在湖泊、水库和海洋中均有异重流现象发生,异重流总会卷吸周边流体进入流动。通过理论分析研究卷吸系数,指出必须不断有一定比率的周边流体被卷吸进入流动,异重流的流速才能保持恒定而不是不断加速。根据这一原理,推导出卷吸系数方程,... 详细信息

在湖泊、水库和海洋中均有异重流现象发生,异重流总会卷吸周边流体进入流动。通过理论分析研究卷吸系数,指出必须不断有一定比率的周边流体被卷吸进入流动,异重流的流速才能保持恒定而不是不断加速。根据这一原理,推导出卷吸系数方程,并且说明了卷吸系数不仅与理查逊数有关,也与密度分布和流速分布密切相关,后两者与流动床面的糙度密切相关。卷吸系数大意味着异重流快速与清水掺混,从潜入点运行较短的距离后密度就会降低到临界密度差之下而停止。由此推导出异重流可以运行的最大距离,与异重流初始流量和密度差成正比,与卷吸系数成反比。小浪底水库的实测资料也说明,在水库里只有初始流量和含沙量较高的异重流才能到达坝前。

关键词：异重流卷吸系数理查逊数流速分布浓度分布

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马达加斯加

疯狂英语（初中天地） 2005年第8期 10-11页

作者： Ann parker 芥子

The Story故事情节The animation focuses on four “stars”of the Central Park Zoo in New York City:a lion(Alex),a ze- bra(Marty),a giraffe(Melman) and a pregnant hippo (Gloria).Not content to live well enough alone,Mart... 详细信息

关键词：马达加斯加亚历克斯格洛里亚动物园