检索结果-南通市图书馆

Nano Research 2024年第5期17卷 4089-4099页

作者： Taili Du Dianlong Shen Ziyue Xi Hongyong Yu Fangyang Dong Cong Zhao meixian zhu Yongjiu Zou Peiting Sun Minyi Xu Dalian Key Laboratory of Marine Micro/Nano Energy and Self-powered Systems Marine Engineering CollegeDalian Maritime UniversityDalian 116026China Collaborative Innovation Research Institute of Autonomous Ship Dalian Maritime UniversityDalian 116026China

An enormous number of wireless sensing nodes(WSNs)are of great significance for the Internet of Things(IoT).It is tremendously prospective to realize the in-situ power supply of WSNs by harvesting unutilized mechanical vibration energy.A harmonic silicone rubber triboelectric nanogenerator(HSR-TENG)is developed focusing on ubiquitous constant working frequency *** unique design of the strip serving as a flexible resonator realizes both soft contact and high and broadband *** significant factors influencing the 1^(st)-order vibration mode of the strip are developed for realizing the harmonic frequency adaptation to external *** surface treatment of the strip improves the output performance of HSR-TENG by 49.1%as well as eliminates the adhesion *** HSR-TENG is able to achieve a voltage output bandwidth of 19 Hz under a vibration strength of 3.0,showing its broadband *** peak power density of 153.9 W/m^(3)is achieved and 12×0.5 W light-emitting diodes(LEDs)are successfully illuminated by the *** can continuously power a temperature sensor by harvesting the actual compressor vibration *** brief,the HSR-TENG provides a promising way for constant frequency vibration energy harvesting,so as to achieve in-situ power supply for the WSNs in the vicinity.

关键词： vibration energy harvesting triboelectric nanogenerator flexible silicone rubber strip harmonic vibration broadband

基于Exercise as Self-care理论的运动管理方案在急性白血病患者化疗康复管理中的应用

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

全科医学临床与教育 2023年第12期21卷 1150-1152页

作者：朱诗卉孙文瑞朱美仙温州医科大学附属第一医院血液内科浙江温州325006

急性白血病是一类造血干细胞异常的白血病类型,其具体病因尚未完全明确,可能与遗传、感染、辐射等因素密切相关[1]。化疗是临床治疗急性白血病最有效的手段,已经在临床得到广泛应用[2]。但是化疗药物选择性较差,在杀灭癌细胞的同时会大... 详细信息

急性白血病是一类造血干细胞异常的白血病类型,其具体病因尚未完全明确,可能与遗传、感染、辐射等因素密切相关[1]。化疗是临床治疗急性白血病最有效的手段,已经在临床得到广泛应用[2]。但是化疗药物选择性较差,在杀灭癌细胞的同时会大量损伤人体正常细胞和重要脏器,破坏机体免疫系统功能,具有极强的毒副作用,严重影响患者康复依从性和预后生活质量[3,4]。

关键词：急性白血病白血病类型康复管理康复依从性人体正常细胞毒副作用化疗药物预后生活质量

在线全文

学校读者我要写书评

暂无评论

初中生英语听说学习问题及改进策略

新课程学习(下) 2014年第8期 66-66页

作者：朱美先江苏省东海县横沟中学

英语作为形合语言,比汉语更突出音型的对应。听说能力既是交际中的主要工具,也是英语能力的领导力量。听说学习要突出"听"的作用,充分发挥听在语言学习上的基础作用,多渠道练习听说,提高听说能力,构建英语交际能力。

关键词：听说问题意义培养策略

A new strategy to improve the sensitivity and selectivity of dopamine detection

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Science China Chemistry 2015年第5期58卷 892-898页

作者： Xiang Xie Jing Gu Wenbo Zhao Shujuan Liu Yonghui Qiao Xinyu zhu Xiaohong Yin Zhiwei zhu meixian Li Yuanhua Shao Institute of Nuclear Chemistry and Physics China Academy of Engineering Physics Beijing National Laboratory for Molecular Sciences College of Chemistry and Molecular Engineering Peking University

We applied the combination of in situ electrochemical liquid-phase microextraction and square-wave voltammetric stripping analysis for the first time as a highly sensitive and selective approach for the detection of dopamine. A mixed gel of graphene sheets and an ionic liquid of 1-octyl-3-methylimidazolium hexaflurophosphate(OMim PF6) was used as a micro liquid-phase to pre-concentrate dopamine by controlled potential electrolysis from an aqueous solution(as a donor phase), followed by square-wave voltammetric stripping detection. Under optimized conditions, a linear calibration curve was obtained in the range of 0.05 to 1.0 ?mol/L in the presence of excess ascorbic acid and uric acid. The detection limit has been found to be 8.0 nmol/L(S/N=3).

关键词： dopamine detection graphene/OMimPF6 gel-modified electrode electrochemical microextraction square-wavevoltammetric stripping

C-dots assisted synthesis of gold nanoparticles as labels to catalyze copper deposition for ultrasensitive electrochemical sensing of proteins

在线全文

学校读者我要写书评

暂无评论

Science China Chemistry 2018年第4期61卷 476-482页

作者： Xiaoli Qin Yifan Dong Minghan Wang Zhiwei zhu meixian Li Xiangjian Chen Di Yang Yuanhua Shao Beijing National Laboratory for Molecular Sciences College of Chemistry and Molecular EngineeringPeking University Institute of Cardiovascular Disease First Affiliated Hospital of Nanjing Medical University

We report an ultrasensitive protocol for electrochemical sensing using the hydroxyl-rich C-dots assisted synthesis of gold nanoparticles(C-dots@AuNP) as labels with copper depositon reaction. The C-dots catalyzing copper deposition reaction was implemented for the first time. We constructed a sandwich-type immunosensor on the chitosan modified glassy carbon electrode(GCE) by glutaraldehyde(GA) crosslinking, with C-dots@AuNP as biolabels. Copper was deposited on the catalytic surfaces of second antibody-conjugated C-dots@AuNP nanoparticles through CuSO_4-ascorbic acid reduction, because both C-dots and AuNPs could strongly catalyze the CuSO_4 and ascorbic acid to form Cu particles, which amplified the detection signal. Then the corresponding antigen was quantified based on simultaneous chemical-dissolution/cathodic-preconcentration of copper for insitu analysis using anodic stripping square wave voltammetry(ASSWV) directly on the modified electrode. Under optimized conditions, these electrodes were employed for sandwich-type immunoanaly sis, pushing the lower limits of detection(LODs)down to the fg mL^(-1) level for human immunoglobulin G(IgG) and cardiac troponin I(cTnI), a cardiac biomarker. These novel sensors have good stability and acceptable accuracy and reproducibility, suggesting potential applications in clinical diagnostics.

关键词： gold nanoparticles with C-dots as labels copper deposition reaction for signal enhancement human immunoglobulin G human cardiac troponin I

在线全文

学校读者我要写书评

暂无评论

三指保护会阴法应用体会

护理研究 1998年第6期12卷 9-9页

作者：朱梅仙,巩向玲山东省青岛市胶州中心医院山东省胶州市人民医院

以往保护会阴用右手拇指、示指分开，虎口向上，手掌托住会阴部。自１９９１年２月始改用三指保护会阴法接生２００余例，效果较好，现介绍如下。１操作方法接生时，助产者站在产妇右侧，当胎头拨露１ｃｍ～２ｃｍ时，助产者用左手示指... 详细信息

以往保护会阴用右手拇指、示指分开，虎口向上，手掌托住会阴部。自１９９１年２月始改用三指保护会阴法接生２００余例，效果较好，现介绍如下。１操作方法接生时，助产者站在产妇右侧，当胎头拨露１ｃｍ～２ｃｍ时，助产者用左手示指、中指、无名指及小指轻压胎头枕部，...

关键词：保护会阴会阴裂伤小指示指中指会阴撕裂胎头拨露助产者会阴中心腱

Inhibition of bacterial adhesion and biofilm formation by a textured fluorinated alkoxyphosphazene surface

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Bioactive Materials 2021年第2期6卷 447-459页

作者： meixian Tang Chen Chen Jieru zhu Harry R.Allcock Christopher A.Siedlecki Li-Chong Xu Department of Biomedical Engineering The Pennsylvania State UniversityUniversity ParkPA16802United States Department of Chemistry The Pennsylvania State UniversityUniversity ParkPA16802United States Department of Surgery The Pennsylvania State UniversityCollege of MedicineHersheyPA17033United States

The utilization of biomaterials in implanted blood-contacting medical devices often induces a persistent problem of microbial infection,which results from bacterial adhesion and biofilm formation on the surface of *** this research,we developed new fluorinated alkoxyphosphazene materials,specifically poly[bis(octafluoropentoxy)phosphazene](OFP)and crosslinkable OFP(X–OFP),with improved mechanical properties,and further modified the surface topography with ordered pillars to improve the antibacterial *** X–OFP materials,X–OFP3.3,X–OFP8.1,X–OFP13.6,with different crosslinking densities were synthesized,and textured films with patterns of 500/500/600 nm(diameter/spacing/height)were fabricated via a two stage soft lithography molding *** with 3 bacterial strains:Staphylococcal epidermidis,Staphylococcal aureus,and Pseudomonas aeruginosa showed that bacterial adhesion coefficients were significantly lower on OFP and X–OFP smooth surfaces than on the polyurethane biomaterial,and surface texturing further reduced bacterial adhesion due to the reduction in accessible surface contact *** the anti-bacterial adhesion effect shows a positive relationship with the crosslinking *** formation on the substrates was examined using a CDC biofilm reactor for 7 days and no biofilm formation was observed on textured X–OFP *** results suggested that the combination of fluorocarbon chemistry and submicron topography modification in textured X–OFP materials may provide a practical approach to improve the biocompatibility of current biomaterials with significant reduction in risk of pathogenic infection.

关键词： Fluorinated polyphosphazene Textured surface Crosslinking Anti-bacterial adhesion Anti-biofilms Microbial infection

家蚕追寄蝇虾红素样精液蛋白酶EsSemp的基因克隆与特性分析

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

蚕业科学 2024年第3期50卷 222-231页

作者：王耒耒王闪闪浦月霞刘吉银王梅仙朱娟沈兴家沈中元唐顺明江苏科技大学生物技术学院江苏省蚕桑与畜禽生物技术重点实验室江苏镇江212100 广西壮族自治区蚕业技术推广站南宁530007 农业农村部蚕桑遗传改良重点实验室中国农业科学院桑蚕科学研究中心江苏镇江212100

虾红素样金属蛋白酶广泛存在于各种昆虫中,参与受精繁殖、孵化及消化等生理功能。为鉴定家蚕追寄蝇生殖繁育相关基因,利用RACE技术克隆获得家蚕追寄蝇虾红素样精液蛋白酶基因全长cDNA序列,命名为EsSemp(GenBank登录号:OP777491),其全长... 详细信息

虾红素样金属蛋白酶广泛存在于各种昆虫中,参与受精繁殖、孵化及消化等生理功能。为鉴定家蚕追寄蝇生殖繁育相关基因,利用RACE技术克隆获得家蚕追寄蝇虾红素样精液蛋白酶基因全长cDNA序列,命名为EsSemp(GenBank登录号:OP777491),其全长为985 bp,ORF为771 bp,编码256个氨基酸残基。以染色体步移技术克隆获得EsSemp完整基因结构,由1个内含子和2个外显子组成。系统发生树结果显示,EsSemp与黑腹果蝇(Drosophila melanogaster)精液蛋白酶基因副本的产物CG15254高度同源。qRT-PCR结果显示,EsSemp在雄蝇副性腺表达较弱,在蝇蛆和成蝇的中肠和马氏管表达较强,在卵期0 h和卵后期大量表达,推测EsSemp参与了受精、孵化与消化代谢等过程。体外表达EsSemp蛋白,结果显示EDTA可抑制EsSemp酶活。以上研究结果为进一步阐明家蚕追寄蝇繁殖发育相关分子机制提供了参考,为开发家蚕蝇蛆病防治新途径提供了基础信息。

关键词：家蚕追寄蝇虾红素样蛋白酶基因 RACE 繁殖发育蛋白质表达

在线全文

学校读者我要写书评

暂无评论

1例白血病病人会阴部坏死的护理

护理研究（上旬版） 2008年第7期22卷 1780-1780页

作者：田园孙月华朱美仙温州医学院附属第一医院

白血病病人化疗后出现粒细胞缺乏(外周血中中性粒细胞的绝对值低于0.5×109/L)时具有很大的感染危险性.现报告1例白血病病人化疗后粒细胞缺乏,并出现会阴部血肿至局部坏死的病人,通过密切观察病情,加强坏死局部创面处理和全身支持治疗,... 详细信息

白血病病人化疗后出现粒细胞缺乏(外周血中中性粒细胞的绝对值低于0.5×109/L)时具有很大的感染危险性.现报告1例白血病病人化疗后粒细胞缺乏,并出现会阴部血肿至局部坏死的病人,通过密切观察病情,加强坏死局部创面处理和全身支持治疗,重视病人及家属的心理护理和教育,病人住院1个月后痊愈出院.

关键词：白血病病人局部坏死心理护理会阴部粒细胞缺乏全身支持治疗中性粒细胞创面处理

N-聚糖合成通路中内质网α-1,2甘露糖苷酶和α-甘露糖苷酶Ⅱ基因对家蚕胚胎滞育的调控作用

在线全文

学校读者我要写书评

暂无评论

蚕业科学 2024年第2期50卷 106-115页

作者：阿依努尔·亚森樊丙炎陈艳花宁阳威王东岳吴赛朱娟王梅仙唐顺明沈兴家江苏科技大学生物技术学院江苏省蚕桑与畜牧生物技术重点实验室江苏镇江212100 中国农业科学院桑蚕研究中心农业农村部蚕桑遗传改良重点实验室江苏镇江212100

家蚕滞育是基因与环境协同作用的结果,其调控网络十分复杂,至今仍未完全阐明。为了解家蚕N-聚糖生物合成通路是否参与胚胎滞育调控,调查家蚕不同化性品系蛹期、胚胎发育早期以及滞育激素(DH)、蜕皮激素(20E)处理后BmN细胞中内质网α-1,... 详细信息

家蚕滞育是基因与环境协同作用的结果,其调控网络十分复杂,至今仍未完全阐明。为了解家蚕N-聚糖生物合成通路是否参与胚胎滞育调控,调查家蚕不同化性品系蛹期、胚胎发育早期以及滞育激素(DH)、蜕皮激素(20E)处理后BmN细胞中内质网α-1,2甘露糖苷酶基因(BmMAN1B)和α-甘露糖苷酶Ⅱ基因(BmMAN2)的转录水平。qRT-PCR结果显示:这2个基因在不同化性品系中的转录水平存在较大差异,蛹晚期的转录水平高于早期;分别用100 nmol/L DH和10 ng/mL 20E处理BmN细胞,BmMAN1B和BmMAN2的转录水平都极显著上调,提示2个基因与家蚕滞育密切相关。对BmN细胞和家蚕二化性品系秋丰165℃催青产非滞育卵组(QFLT)蛹期2 d雌蛹进行BmMAN1B和BmMAN2基因的RNA干扰,结果发现滞育相关基因BmDH、BmDHR-1、BmTRE2和BmSDH-2a等的转录水平发生了变化;当在个体水平进行BmMAN1B和BmMAN2基因的共同干扰时,382%的子代卵由非滞育转变为滞育。结果表明,BmMAN1B和BmMAN2在家蚕胚胎滞育中具有重要的调控作用。

关键词：家蚕滞育 N-糖基化内质网α-1,2甘露糖苷酶 α-甘露糖苷酶Ⅱ