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Mechanisms of Pb(Ⅱ) coprecipitation with natrojarosite and its behavior during acid dissolution

Journal of Environmental Sciences 2022年第12期34卷 128-137页

作者： meiqing shi Xiaobo Min Chen Tian Taixu Hao Sijie Zhu Yun Ge Qingwei Wang Xu Yan Zhang Lin Institute of Environmental Engineering School of Metallurgy and EnvironmentCentral South UniversityChangsha 410083China Chinese National Engineering Research Center for Control&Treatment of Heavy Metal Pollution Changsha 410083China Water Pollution Control Technology Key Lab of Hunan Province Changsha 410004China

Lead(Pb) coprecipitation with jarosite is common in natural and engineered environments,such as acid mine drainage(AMD) sites and hydrometallurgical industry. Despite the high relevance for environmental impact, few studies have examined the exact interaction of Pb with jarosite and the dissolution behavior of each phase. In the present work, we demonstrate that Pb mainly interacts with jarosite in four modes, namely incorporation, occlusion,physically mixing, and chemically mixing. For comparison, the four modes of Pb-bearing natrojarosite were synthesized and characterized separately. Batch dissolution experiments were undertaken on these synthetic Pb-bearing natrojarosites under pH_(2) to simulate the AMD environments. The introduction of Pb decreases the final Fe releasing efficiency of jarosite-type compounds from 18.18% to 3.45%-5.01%, showing a remarkable inhibition of their dissolution. For Pb releasing behavior, PbSO_(4) dissolves in preference to Pb-substituted natrojarosite, i.e.,(Na, Pb)-jarosite, which primarily results in the sharp increase of Pb releasing concentration(> 40 mg/L). PbSO_(4) occlusion by jarosite-type compounds can significantly reduce the release of Pb. The results of this study could provide useful information regarding Fe and Pb cycling in acidic natural and engineered environments.

关键词： Pb-bearing natrojarosite Interaction mechanism Acid dissolution Releasing behavior

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High expression of BCL6 inhibits the differentiation and development of hematopoietic stem cells and affects the growth and development of chickens

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Journal of Animal Science and Biotechnology 2021年第3期12卷 904-916页

作者： Hongmei Li Bowen Hu Shang Hu Wen Luo Donglei Sun Minmin Yang Zhiying Liao Haohui Wei Changbin Zhao Dajian Li meiqing shi Qingbin Luo Dexiang Zhang Qinghua Nie Xiquan Zhang Department of Animal Genetics Breeding and ReproductionCollege of Animal ScienceSouth China Agricultural UniversityGuangzhou 510642Guangdong ProvinceChina Guangdong Provincial Key Lab of AgroAnimal Genomics and Molecular Breeding and Key Lab of Chicken Genetics Breeding and ReproductionMinistry of AgricultureGuangzhou 510642GuangdongChina State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources South China Agricultural UniversityGuangzhou 510642GuangdongChina Division of Immunology Virginia-Maryland College of Veterinary MedicineUniversity of MarylandCollege ParkMDUSA

Background:B-cell CLL/lymphoma 6(BCL6)is a transcriptional master regulator that represses more than 1200 potential target *** previous study showed that a decline in blood production in runting and stunting syndrome(RSS)affected sex-linked dwarf(SLD)chickens compared to SLD ***,the association between BCL6 gene and hematopoietic function remains unknown in ***:In this study,we used RSS affected SLD(RSS-SLD)chickens,SLD chickens and normal chickens as research object and overexpression of BCL6 in hematopoietic stem cells(HSCs),to investigate the effect of the BCL6 on differentiation and development of ***:The results showed that comparison of RSS-SLD chickens with SLD chickens,the BCL6 was highly expressed in RSS-SLD chickens bone *** bone marrow of RSS-SLD chickens was exhausted and red bone marrow was largely replaced by yellow bone marrow,bone density was reduced,and the levels of immature erythrocytes in peripheral blood were *** the same time,the hematopoietic function of HSCs decreased in RSS-SLD chickens,which was manifested by a decrease in the hematopoietic growth factors(HGFs)EPO,SCF,TPO,and IL-3,as well as hemoglobinα1 and hemoglobinβ***,mitochondrial function in the HSCs of RSS-SLD chickens was damaged,including an increase in ROS production,decrease in ATP concentration,and decrease in mitochondrial membrane potential(ΔΨm).The same results were also observed in SLD chickens compared with normal chickens;however,the symptoms were more serious in RSS-SLD ***,after overexpression of the BCL6 in primary HSCs,the secretion of HGFs(EPO,SCF,TPO and IL-3)was inhibited and the expression of hemoglobinα1 and hemoglobinβwas ***,cell proliferation was accelerated,apoptosis was inhibited,and the HSCs entered a cancerous *** function of mitochondria was also abnormal,ROS production was decreased,and ATP concentration andΔΨm were increased,which was related t

关键词： BCL6 Hematopoietic stem cells Mitochondrial function Runting and stunting syndrome Sex-linked dwarf chickens

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Real time in vivo imaging of neutrophils clearing Cryptococcus neoformans from the brain vasculatures

Real time in vivo imaging of neutrophils clearing Cryptococc...

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中华医学会2014全国微生物学与免疫学学术年会

作者：张明顺季晓辉周洪 meiqing shi 南京医科大学基础医学院免疫学系 University of Maryland

Summary Cryptococcus neoformans(Cn)is a leading agent for brain infection in immunocompromised individuals,including AIDS *** released from the lungs is stopped in the brain vasculature by mechanical trapping or receptor-mediated binding and then transmigrates across the blood-brain barrier(BBB),leading to fatal *** real

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