检索结果-南通市图书馆

Transcription factor Foxp1 is essential for the induction of choroidal neovascularization

在线全文

学校读者我要写书评

暂无评论

Eye and Vision 2024年第3期10卷 1-12页

作者： meifang Yan Junjian Li Li Yan Xue Li Jie-Guang Chen School of Ophthalmology and Optometry and Eye Hospital Wenzhou Medical UniversityState Key Laboratory of OptometryOphthalmology and Vision Scienceand Zhejiang Provincial Key Laboratory of Optometry and Ophthalmology270 Xueyuan RoadWenzhouZhejiang325027People’s Republic of China Joint Shantou International Eye Center(JSIEC)of Shantou University and the Chinese University of Hong Kong ShantouGuangdong515000People’s Republic of China

Background The exudative form of age-related macular degeneration(AMD)is characterized by abnormal blood vessel growth,which is stimulated by vascular endothelial growth factor(VEGF)released from retinal pigment epithelium(RPE).The angiogenic behaviors of vascular endothelial cells in vitro depend on forkhead box protein P1(Foxp1),a transcription repressor widely expressed in human and murine tissues during *** this study,we aimed to determine whether loss of Foxp1 affects laser-induced choroidal neovascularization(CNV)in *** Eye-selective deletion of Foxp1 was obtained by crossing Foxp1flox/flox with Six3-Cre *** photocoagulation was delivered to six-to eight-week-old mice to induce *** expression of Foxp1 and Cre was determined by immunofluorescence in cryostat sections of the *** fluorescein angiography(FFA),optical coherence tomography(OCT),and B4 isolectin staining were applied to analyze the leakage,bulge height,and area of CNV lesions,***-choroid tissues were isolated for the determination of VEGF and pigment epithelium derived factor(PEDF)by Western *** Foxp1 was expressed in retinal ganglion cells,RPE,and the choroidal endothelial *** photocoagulation increased the number of Foxp1+-endothelial cells and induced ***3-Cre reduced Foxp1 expression in RPE but not the endothelium,leading to a lower level of VEGF in the ***1 knockout inhibited pathological angiogenesis and vascular leakage of the laser-induced CNV *** Foxp1 regulates the expression of VEGF in the RPE,and inhibition of Foxp1 could potentially be a novel strategy for the prevention and therapy of neovascularization related to AMD.

关键词： Foxp1 Choroidal neovascularization Angiogenesis Laser photocoagulation Age-related macular degeneration

Intermolecular reductive coupling of aliphatic ketones with alkynes and alkenes by BCN photocatalysts

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China Chemistry 2024年

作者： Yanping Xia Luyang Sun Jiajia Cheng Sibo wang meifang Zheng Xinchen wang State Key Laboratory of Photocatalysis on Energy and Environment College of ChemistryFuzhou University

A photocatalytic process was developed for intermolecular reductive coupling of aliphatic ketones with alkynes/alkenes to furnish tertiary *** studies support that boron carbonitrides (BCN) promote the single electron reduction of unactivated aliphatic ketones to generate ketyl radicals with visible light irradiation,which then react with alkynes and alkenes to afford the allylic and aliphatic alcohols,*** heterogeneous photocatalytic system is compatible with diverse substrates including pharmaceutical-related molecules (43 examples) with reusability and scale-up experiments,verifying the complementary synthetic utility of this method to the homogeneous catalysts.

关键词：

光伏-环路热管/热泵热水系统在不同气候区性能对比与优化

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

农业工程学报 2020年第1期36卷 252-256页

作者：李洪王美芳张曼燕山大学建筑工程与力学学院

为改善传统太阳能光伏/光热热水系统运行性能,拓展空气源热泵热水系统应用范围,该文针对一种太阳能光伏-环路热管/热泵热水系统开展了其在3种不同气候区运行性能对比及优化研究。分别选择北京、上海和广州作为寒冷、夏热冬冷和夏热冬暖... 详细信息

为改善传统太阳能光伏/光热热水系统运行性能,拓展空气源热泵热水系统应用范围,该文针对一种太阳能光伏-环路热管/热泵热水系统开展了其在3种不同气候区运行性能对比及优化研究。分别选择北京、上海和广州作为寒冷、夏热冬冷和夏热冬暖地区典型气候代表城市,依据所建数学模型,模拟比对系统在3个地区的全年运行性能,分析了集热/蒸发器的朝向与安装倾角对系统运行性能的影响,并对其进行了优化;以传统空气源热泵热水系统为基准,采用全寿命周期成本计算方法分析了系统的经济可行性。结果表明,相同安装倾角正南朝向时,系统在广州的太阳能综合利用效率最高、节能性最佳;各地区理想安装倾角下,北京和上海正南朝向时系统节能效益最优,广州则南偏东30°时节能率最高;与传统空气源热泵热水系统相比,系统在北京、上海、广州的全寿命周期成本分别降低了58.75%、49.83%及53.09%,经济效益显著。

关键词：太阳能热泵效率气候条件运行性能

An organometallic salt as the electrolyte additive to regulate lithium polysulfide redox and stabilize lithium anodes for robust lithium-sulfur batteries

在线全文

学校读者我要写书评

暂无评论

Science China Materials 2024年第9期67卷 2880-2888页

作者： Yixuan Meng meifang Zhang Youliang wang Chen Liu Ze Zhang Ji Yu Jianxin Cai Zhenyu Yang Key Laboratory of Jiangxi Province for Environment and Energy Catalysis School of Chemistry and Chemical EngineeringNanchang UniversityNanchang330031China Institute of Carbon Neutral New Energy Research Yuzhang Normal UniversityNanchang330031China School of Biological and Chemical Engineering Zhejiang University of Science and TechnologyHangzhou310023China

Lithium-sulfur(Li-S)batteries with high theoretical specific energy are considered to be one of the highly promising next-generation energy storage ***,the shuttle effect of lithium polysulfides(LiPSs)and the interfacial instability of Li anodes have seriously hindered the practical application of Li-S *** the electrolyte composition with additives can significantly improve the battery performance and has attracted great ***,we propose an organometallic salt,i.e.,nickel bromide dimethoxyethane(NiBr_(2)DME),as an electrolyte additive,which serves as the dual function of regulating LiPSs redox and synchronously stabilizing Li *** reveal that NiBr_(2)DME can interact with LiPSs via Ni-S and Li-Br bonds,and accelerate the mutual transformation of LiPSs,thus reducing the accumulation of LiPSs in the *** addition,NiBr_(2)DME can form a stable LiBr-containing interfacial layer on the Li metal surface,and promote the uniform electrodeposition of Li^(+)ions,and inhibit the formation of Li ***,Li-S batteries with a concentration of 0.5 mmol L^(-1)NiBr_(2)DME show an initial capacity of 919.8 mAh g^(-1)at 0.2 C,and a high capacity retention of 89.3%after 100 *** at the 4 C rate,a high discharge capacity of 602.9 mAh g^(-1)is ***,the good cycling performance is maintained under poor electrolyte conditions with sulfur loading of 4.8 mg cm^(-2)and electrlyte/sulfur ratio of 5µL mg^(-1).This work provides a positive solution to achieve the suppression of shuttle effect,the regulation of LiPSs redox and the stabilization of Li anodes.

关键词： Li-S batteries electrolyte additive nickel bromide dimethoxyethane regulating LiPSs redox stabilizing Li anode

Reaction Kinetics and Secondary Organic Aerosol Composition Analysis of 2-Cyclohexen-1-one with NO_(3) Radicals

在线全文

学校读者我要写书评

暂无评论

Chemical Research in Chinese Universities 2024年第4期40卷 730-736页

作者： HU Lin TONG Shengrui XU Yanyong ZHANG Hailiang YU Shanshan CHEN meifang GE Maofa Structural Chemistry of Unstable and Stable Species Chinese Academy of Sciences Research/Education Center for Excellence in Molecular SciencesInstitute of ChemistryChinese Academy of SciencesBeijing100190P.R.China College of Ecology and Environment Xinjiang UniversityUrumqi830017P.R.China University of Chinese Academy of Sciences Beijing100049P.R.China

Unsaturated ketones are typical oxygenated volatile organic compounds(OVOCs)with high reactivity,and are important precursors in air *** sources of OVOCs are complex and include direct emissions and secondary oxidation formation of VOCs in the atmosphere.2-Cyclohexen-1-one is a widespread substance,and is derived from the industrial catalytic oxidation of *** this paper,we investigated the rate constants of the chemical reactions of 2-cyclohexen-1-one with NO_(3) radicals,which is(7.25±0.29)×10^(-15) cm^(3)·molecule^(-1)·s^(-1) at 298 K and under 1 atm(1 atm=101325Pa).It supplemented the kinetics of NO_(3) radicals database,and revealed its effects in the nighttime *** addition,the reaction products of 2-cyclohexen-1-one with NO_(3) radicals were detected by Fourier transform ion cyclotron resonance mass spectrometry(FT-ICR MS),which revealed a series of nitrate esters in the composition of the secondary organic aerosol(SOA),which may reduce atmospheric ***,the possible pathways for the generation of the products were developed.

关键词： Kinetics Unsaturated ketone Nitrate radical Secondary organic aerosol

Controllable large-scale processing of temperature regulating sheath-core fibers with high-enthalpy for thermal management

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Materials Science 2024年第3期6卷 337-344页

作者： Ziye Chen Zexu Hu Shining Chen Senlong Yu Liping Zhu Hengxue Xiang meifang Zhu Key Laboratory for Modification of Chemical Fibers and Polymer Materials College of Materials Science and EngineeringDonghua UniversityShanghai201620China College of Mechanical and Engineering Donghua UniversityShanghai201620China

Temperature regulating fibers(TRF_(s)) with high enthalpy and high form stability are the key factors for thermal management. However, the enthalpies of most TRFsare not high, and the preparation methods are still at the laboratory scale. It remains a great challenge to use industrial spinning equipment to achieve continuous processing of TRF_(s) with excellent thermal and mechanical properties. Here, polyamide 6(PA6) based TRF_(s) with a sheath-core structure were prepared by bicomponent melt-spinning. The sheath-core TRF(TRF_(sc)) are composed of PA6 as sheath and functional PA6 as core, which are filled with the shape stable phase change materials(ssPCM),dendritic silica@polyethylene glycol(SiO_(2)@PEG). With the aid of the sheath structure, the filling content of SiO_(2)@PEG can reach 30 %, so that the enthalpy of the TRF_(s) can be as high as 21.3 J/g. The ultra-high enthalpy guarantees the temperature regulation ability during the alternating process of cooling and heating. In hot environment, the temperature regulation time is 6.59 min, and the temperature difference is 12.93℃. In addition, the mechanical strength of the prepared TRF_(sc) reaches 2.26 cN/dtex, which can fully meet its application in the field of thermal management textiles and devices to manage the temperature regulation of the human body or precision equipment, etc.

关键词： Thermal management Hybrid fibers Polyamides Bicomponent melt spinning Temperature regulating fibers

Constructing on-demand single/multi-color transitioning fabrics with photocatalysis/photothermal-armed deficient semiconductors

在线全文

学校读者我要写书评

暂无评论

Nano Research 2024年第5期17卷 3633-3643页

作者： Daniel K.Macharia Shamima Sarker Meng Liu Zeyulong Wen Nuo Yu meifang Zhu Zhigang Chen State Key Laboratory for Modification of Chemical Fibers and Polymer Materials College of Materials Science and EngineeringDonghua UniversityShanghai 201620China

On-demand color switching systems that utilize synchronized semiconductor-catalyzed reduction and photothermal-accelerated oxidation in liquid/solid are highly ***,on-demand single/multi-color switching fabrics have been constructed by using defective SnO_(2):Sb-based color switching ***_(2):Sb nanocrystals with the suitable doping concentration accord lattices with abundant free electrons,conferring high photocatalytic and photothermal performances.A well-crafted set of dual light-responsive semiconductor-catalyzed systems with rapid color change can be attained via the homogenous mixture of SnO_(2):Sb with suitable redox dyes to produce single-color(RGB(red,green,blue))and multi-color transitioning(purple and green)*** illumination of these systems by 450 nm light triggers rapid photocatalytic discoloration,while irradiation by 980 nm light confers the photothermal effect that accelerates recoloration in ***,the inks can be extended to rewritable fabrics by embedding the nanocrystals and redox dyes into hydroxyethyl cellulose(as the polymer matrix)and then coating on hydrophobic cotton fabrics to produce photo-switchable fabrics with excellent single/multi-color *** exploiting the dual light interactions with the semiconductor-mediated systems,various images/letters can be remotely printed and erased on the rewritable fabrics which show promise for potential applications as information storage media and visual ***,the present rewritable fabric shows good stability and *** present work provides insights into the development of novel color-switching materials.

关键词： color switching defective semiconductor photocatalysis photothermal rewritable fabrics

ADAPTIVE CONTROL OF LINEAR VELOCITY AND TENSION IN WINDING SYSTEM OF DRY PLASTIC FILM LAMINATING MACHINE

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

ADAPTIVE CONTROL OF LINEAR VELOCITY AND TENSION IN WINDING S...

2006年中国机械工程学会年会暨中国工程院机械与运载工程学部首届年会

作者： CHEN Dechuan, wang meifang Hangzhou Dianzi University, Hangzhou 310018, China

Based on the control principle of the dry plastic film laminating machine, and the linear velocity synchronization and variable tension control in the winding process for the two-layer film laminating

关键词： Dry film laminating machine tension control—linear velocity coordination winding control adaptive control.

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

儿童特质概念发展的理论及其进展

山东师范大学学报（人文社会科学版） 2007年第1期52卷 124-128页

作者：王美芳山东师范大学心理学院山东济南250014

近30年来对儿童特质概念发展的理论探讨一直是儿童社会认知发展研究中的一个重要课题。随着儿童特质概念发展研究的不断深入和近期儿童心理理论研究热潮的兴起,有关儿童特质概念发展的理论也从皮亚杰的认知发展理论、韦纳的归因理论和... 详细信息

近30年来对儿童特质概念发展的理论探讨一直是儿童社会认知发展研究中的一个重要课题。随着儿童特质概念发展研究的不断深入和近期儿童心理理论研究热潮的兴起,有关儿童特质概念发展的理论也从皮亚杰的认知发展理论、韦纳的归因理论和凯斯的信息加工理论等一般认知理论发展为儿童心理理论取向的理论。但在儿童特质概念发展的研究中,尚存在一些基础性的问题有待于进一步的理论探讨。

关键词：儿童特质概念发展理论观点