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Effect of adding a smart potassium ion-responsive copolymer into polysulfone support membrane on the performance of thin-film composite nanofiltration membrane

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Frontiers of Chemical Science and Engineering 2019年第2期13卷 400-414页

作者： meibo he Zhuang Liu Tong Li Chen Chen Baicang Liu John C.Crittenden Institute of New Energy and Low-Carbon Technology Sichuan UniversityChengdu 610207China College of Architecture and Environment Sichuan UniversityChengdu 610065China School of Chemical Engineering Sichuan UniversityChengdu 610065China Research Center for Eco-Environmental Sciences Chinese Academy of SciencesBeijing 100085China Litree Purifying Technology Co. LtdHaikou 571126China Brook Byers Institute for Sustainable Systems School of Civil and Environmental EngineeringGeorgia Institute of TechnologyAtlantaGA 30332USA

Thin-film composite (TFC) nanofiltration (NF) membranes were fabricated via the interfacial polymerization of piperazine (PIP) and 1,3,5-benzenetricart)oiiyl trichloride on polysulfone (PSf) support membranes blended with K^+-responsive poly(N-isopropylacryamideco- acryloylamidobenzo-15-crown-5)(P(NIPAM-co- AAB15C5)). Membranes were characterized by attenuated total reflection Fourier transform infrared spectroscopy, X-ray photoelectron spectroscopy, atomic force microscope, scanning electron microscope, contact angle, and filtration tests. The results showed that:(1) Under K^+-free conditions, the blended P(NIPAM-co-AAB15C5)/PSf supports had porous and hydrophilic surfaces, thereby producing NF membranes with smooth surfaces and low MgSO4 rejections;(2) With K^+ in the PIP solution, the surface roughness and water permeability of the resultant NF membrane were increased due to the K^+-induced transition of low-content P(NIPAM-co-AAB15C5) from hydrophilic to hydrophobic;(3) After a curing treatment at 95℃, the improved NF membrane achieved an even higher pure water permeability of 10.97 L·m^-2·h^-1 - bar1 under 200 psi. Overall, this study provides a novel method to improve the performance of NF membranes and helps understand the influence of supports on TFC membranes.

关键词： nanofiltration interfacial polymerization support membrane potassium ion-responsive thin-film composite

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Increased Expression of Colonic Mucosal Melatonin in Patients with Irritable Bowel Syndrome Correlated with Gut Dysbiosis

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Genomics, Proteomics & Bioinformatics 2020年第6期18卷 708-720页

作者： Ben Wang Shiwei Zhu Zuojing Liu Hui Wei Lu Zhang meibo he Fei Pei Jindong Zhang Qinghua Sun Liping Duan Department of Gastroenterology Peking University Third HospitalBeijing 100191China Department of Pathology School of Basic Medical SciencesPeking UniversityBeijing 100191China Institute of Systems Biomedicine School of Basic Medical SciencesPeking UniversityBeijing 100191China

Dysregulation of the gut microbiota/gut hormone axis contributes to the pathogenesis of irritable bowel syndrome(IBS).Melatonin plays a beneficial role in gut motility and ***,altered expression of local mucosal melatonin in IBS and its relationship with the gut microbiota remain ***,we aimed to detect the colonic melatonin levels and microbiota profiles in patients with diarrhea-predominant IBS(IBS-D)and explore their relationship in germ-free(GF)rats and BON-1 ***-two IBS-D patients and twenty-eight healthy controls(HCs)were *** specimens from IBS-D patients and HCs were separately transplanted into GF rats by *** levels of colon mucosal melatonin were assessed by immunohistochemical methods,and fecal microbiota communities were analyzed using 16S rDNA *** effect of butyrate on melatonin synthesis in BON-1 cells was evaluated by *** levels were significantly increased and negatively correlated with visceral hypersensitivity in IBS-D *** rats inoculated with fecal microbiota from IBS-D patients had high colonic melatonin ***-producing Clostridium cluster XIVa species,such as Roseburia species and Lachnospira species,were positively related to colonic mucosal melatonin *** significantly increased melatonin secretion in BON-1 *** melatonin expression may be an adaptive protective mechanism in the development of ***,some Clostridium cluster XIVa species could increase melatonin expression via butyrate *** of the gut hormone/gut microbiota axis offers a promising target of interest for IBS in the future.

关键词： Irritable bowel syndrome Melatonin Gut microbiota Fecal microbiota transplantation Butyrate

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Patients with breath test positive are necessary to be identified from irritable bowel syndrome:a clinical trial based on microbiomics and rifaximin sensitivity

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Chinese Medical Journal 2022年第14期135卷 1716-1727页

作者： Zuojing Liu Shiwei Zhu meibo he Mo Li Hui Wei Lu Zhang Qinghua Sun Qiong Jia Nan Hu Yuan Fang Lijin Song Chen Zhou heqing Tao John Y Kao Huaiqiu Zhu Chung Owyang Liping Duan Department of Gastroenterology Peking University Third HospitalHaidian DistrictBeijing 100191China Department of Ultrasound Peking University Third HospitalHaidian DistrictBeijing 100191China Institute of Systems Biomedicine School of Basic Medical SciencesPeking University Health Science CenterBeijing 100191China Department of Biomedical Engineering College of EngineeringPeking UniversityBeijing 100187China Division of Gastroenterology Department of Internal MedicineUniversity of Michigan Health System6520 MSRB ISPC 56821150 West Medical Center DriveAnn ArborMI 48109USA

Background:As a non-invasive and effective diagnostic method for small intestinal bacterial overgrowth(SIBO),wild-use of breath test(BT)has demonstrated a high comorbidity rate in patients with diarrhea-predominant irritable bowel syndrome(IBS-D)and *** overlapping with SIBO respond better to rifaximin therapy than those with IBS-D *** microbiota plays a critical role in both of these two *** aimed to determine the microbial difference between IBS-D overlapping with/without SIBO,and to study the underlying mechanism of its sensitivity to ***:Patients with IBS-D were categorized as BT-negative(IBSN)and BT-positive(IBSP).healthy volunteers(BT-negative)were enrolled as healthy *** patients were clinically evaluated before and after rifaximin treatment(0.4 g bid,4 weeks).Blood,intestine,and stool samples were collected for cytokine assessment and gut microbial ***:Clinical complaints and microbial abundance were significantly higher in IBSP than in *** contrast,severe systemic inflammation and more active bacterial invasion function that were associated with enrichment of opportunistic pathogens were seen in *** symptoms of IBSP patients were relieved in different degrees after therapy,but the symptoms of IBSN rarely *** also found that the presence of IBSN-enriched genera(Enterobacter and Enterococcus)are unaffected by rifaximin ***:IBS-D patients overlapping with SIBO showed noticeably different fecal microbial composition and function compared with IBS-D *** better response to rifaximin in those comorbid patients might associate with their different gut microbiota,which suggests that BT is necessary before IBS-D diagnosis and use of ***:Chinese Clinical Trial Registry,ChiCTR1800017911.

关键词： Irritable bowel syndrome Small intestinal bacterial overgrowth Breath test Gut microbiota Rifaximin

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宽中健脾汤联合肠内营养在神经危重症患者治疗中的临床应用

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四川中医 2020年第9期38卷 89-93页

作者：邓开勇刘福贺美波周超川北医学院附属医院药剂科四川南充637000

目的:观察宽中健脾汤联合肠内营养治疗神经危重症患者的疗效。方法:遴选2017年4月~2018年4月期间90例神经危重患者,选用密封信封法以1:1比例随机分为对照组和观察组,每组45例,均给予常规对症治疗,对照组给予肠内营养支持,观察组基于以... 详细信息

目的:观察宽中健脾汤联合肠内营养治疗神经危重症患者的疗效。方法:遴选2017年4月~2018年4月期间90例神经危重患者,选用密封信封法以1:1比例随机分为对照组和观察组,每组45例,均给予常规对症治疗,对照组给予肠内营养支持,观察组基于以上治疗给予宽中健脾汤治疗,观察两组治疗前及治疗10d的中医主要症状体征积分、临床疗效、治疗前及治疗10d后的营养指标、免疫功能指标,对比组间治疗第1、4、7、10d的氮平衡值,统计两组并发症情况。结果:治疗后,两组患者的中医主要症状体征总积分显著降低(P<0.05),观察组显著低于对照组(P<0.05);观察组的中医证候总有效率显著高于对照组(93.33%vs 73.33%,P<0.05);治疗后,两组血清总蛋白(TP)、前白蛋白(pre-ALB)、视黄醇结合蛋白(sRBP)及白蛋白(ALB)水平显著升高(P<0.05),观察组的变化幅度显著大于对照组(P<0.05);治疗后,观察组血清总淋巴细胞计数(TLC)、免疫球蛋白M(IgM)、免疫球蛋白G(IgG)、免疫球蛋白M(IgA)水平显著升高(P<0.05),且均高于对照组(P<0.05);治疗第4、7、10d,两组的氮平衡值显著高于治疗第1d(P<0.05),观察组改善效果显著优于对照组(P<0.05);观察组的并发症总发生率(11.11%)显著低于对照组(17.78%)(P<0.05)。结论:宽中健脾汤联合肠内营养治疗神经危重症的疗效确切,可明显改善患者相关症状体征、营养状况和免疫系统功能,利于其快速恢复氮平衡,减少并发症发生风险。

关键词：宽中健脾汤肠内营养神经危重症

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高效液相色谱法测定甲硝唑氯霉素栓中两种成分的含量

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中国医药导报 2012年第16期9卷 124-125页

作者：罗飞贺美波罗巧林川北医学院附属医院药剂科四川南充637000

目的建立高效液相色谱法测定甲硝唑氯霉素栓中两种主成分含量的方法。方法采用Hypersil ODS柱(150.0 mm×4.6 mm,5μm),甲醇-乙腈-水(50∶5∶45)为流动相,280 nm为检测波长,流速1 mL/min。结果甲硝唑和氯霉素的线性范围分别为49.28～295... 详细信息

目的建立高效液相色谱法测定甲硝唑氯霉素栓中两种主成分含量的方法。方法采用Hypersil ODS柱(150.0 mm×4.6 mm,5μm),甲醇-乙腈-水(50∶5∶45)为流动相,280 nm为检测波长,流速1 mL/min。结果甲硝唑和氯霉素的线性范围分别为49.28～295.68μg/mL(r=0.999 1,n=6)和24.32～145.92μg/mL(r=0.999 2,n=6),平均回收率分别为98.70%和97.46%,RSD分别为0.68%和0.75%(n=9)。结论本法重复性好,准确度高,适用于制剂含量测定。

关键词：高效液相色谱法甲硝唑氯霉素栓甲硝唑氯霉素含量

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正交试验法优选消癌平胶囊提取工艺

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国际中医中药杂志 2020年第11期42卷 1119-1124页

作者：邓开勇刘福贺美波周超四川省川北医学院附属医院药剂科南充637000

目的优选消癌平胶囊的最佳水提醇沉工艺。方法采用正交试验法,以通关藤苷G含量和干浸膏率为指标,考察煎煮次数、煎煮时间、加水量对消癌平胶囊水提取工艺的影响;考察醇沉浓度、相对密度、静置时间对其醇沉工艺的影响。结果优选的水提工... 详细信息

目的优选消癌平胶囊的最佳水提醇沉工艺。方法采用正交试验法,以通关藤苷G含量和干浸膏率为指标,考察煎煮次数、煎煮时间、加水量对消癌平胶囊水提取工艺的影响;考察醇沉浓度、相对密度、静置时间对其醇沉工艺的影响。结果优选的水提工艺为加6倍量的水煎煮3次,每次1.5 h;优选的醇沉工艺为水提液浓缩至相对密度为1.15(60 ℃),冷却后加入乙醇,使含醇量为70%,静置12 h,除去沉淀。结论优选的水提醇沉工艺稳定可行、重现性好,可为消癌平胶囊的提取纯化提供参考。

关键词：正交试验消癌平胶囊水提醇沉通关藤苷G 中药工艺改进

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An Update Review on Performance Enhancement of Refrigeration Systems Using Nano-Fluids

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Journal of Thermal Science 2022年第4期31卷 1236-1251页

作者： XING meibo ZHANG Hongfa ZHANG Cancan Beijing Engineering Research Center of Sustainable Energy and Buildings School of Environment and Energy EngineeringBeijing University of Civil Engineering and ArchitectureBeijing 100044China MOE Key Laboratory of Enhanced heat Transfer and Energy Conservation Beijing Key Laboratory of Heat Transfer and Energy ConversionBeijing University ofTechnologyBeijing 100124China

Considering the issues of energy saving and environment protection,the performance of refrigeration systems requires to be *** recent years,nano-fluids have attracted greatly attention from the researchers due to their outstanding thermal *** this work,the published investigations on the preparation and characterization of nano-fluids have been discussed at ***,the key thermo-physical properties of nano-fluids,such as thermal conductivity,viscosity,specific heat and density have been ***,the performance enhancements in different types of refrigeration systems by using nano-fluids have been *** is concluded that nano-fluids as refrigerant,lubricant or secondary fluid have wide potential application in refrigeration systems.

关键词： nano-fluids performance enhancement nano-refrigerant nano-lubricant nano-secondary fluid refrigeration

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Scaling Behavior between heat Capacity and Thermal Expansion in Solids

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Chinese Physics Letters 2021年第2期38卷 69-73页

作者： meibo Tang Xiuhong Pan Minghui Zhang Haiqin Wen Shanghai Institute of Ceramics Chinese Academy of SciencesShanghai 200050China

We experimentally analyze the heat capacity and thermal expansion of reference solids in a wide temperature range from several Kelvin to melting temperature,and establish a universal double-linear relation between the experimental heat capacity C_(p) and thermal expansion β,which is different from the previous *** universal behavior between heat capacity and thermal expansion is important to predict the thermodynamic parameters at constant pressure,and is helpful for understanding the nature of thermal properties in solids.

关键词： solids expansion thermal

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How China’s Aid helps Recipient Countries Build Export Capacity

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China Economist 2021年第2期16卷 2-16页

作者： Yan Hongrong Zhang Xiaolu Huang meibo International Development Cooperation Academy Shanghai University of International Business and EconomicsShanghaiChina School of Social Science and Institute for Innovation and Development Tsinghua UniversityBeijingChina

Based on data of China’s aid to 120 countries and recipient countries’export data between 2002-2014,this paper investigated the export effects of China’s *** found that China’s aid was conducive to recipient countries’exports to China,helping recipient countries boost their development capacity and meet China’s consumption demand at the same *** this manner,China’s foreign aid has lived up to the principle of“mutually beneficial cooperation”.heterogeneity test found that China’s aid helped recipient countries increase their exports of manufacturing goods of their comparative advantage,mainly medium-and low-end manufacturing products,to China without increasing the exports of non-manufacturing goods,such as agricultural produce as well as primary and resource *** findings have thoroughly refuted criticisms like the“resource exploitation”narrative by Western countries against *** from increasing African countries’exports to China,China’s aid also helped other recipient countries outside Africa,mostly medium-and low-income recipient countries,to export more to ***’s aid-fortrade(AfT)programs did not significantly increase recipient countries’capacity to export to China.A test of the mechanism of action found that industrial development in recipient countries exerted only a partial intermediate effect in enhancing recipient countries’capacity to export to China.

关键词： foreign aid recipient countries export capacity mutually beneficial cooperation

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Optical,thermal and luminescence properties of La2O3-Ga2O3-ZrO2 glasses co-doped with Tm3+/Yb3+prepared by containerless technique

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Journal of Rare Earths 2022年第11期40卷 1706-1714,I0002页

作者： Jiansheng Xie Minghui Zhang Yanzhuo Wang Rongting Guo Ying Shi Xiuhong Pan Xuechao Liu Kun Chen meibo Tang Feng Wu Zhihong Zhang School of Materials Science and Engineering Shanghai UniversityShanghai 200444China State Key Laboratory of High Performance Ceramics and Superfine Microstructure Shanghai Institute of CeramicsChinese Academy of SciencesShanghai 200050China Hubei Key Laboratory of Plasma Chemistry and Advanced Materials Wuhan Institute of TechnologyWuhan 430205China College of Chemical and Biological Engineering Guilin University of TechnologyGuangxi Key Laboratory of Electrochemical and Magneto-chemical Functional MaterialsGuilin 541004China AECC-Chengdu Chengdu 610500China

Bulk LaO-GaO-ZrO(LGZ)glass and Tm/Ybco-doped LGZ glasses were synthesized successfully using containerless *** spectra result reveals that the matrix sample possesses the low maximum phonon energy of~642 *** glasses show good compatibility between large Abbe numbers(>31)and high refractive indices(n>1.93).Moreover,transmittance measurements reflect that the glasses have high infrared transmittance of-81.9%,small OHabsorption coefficient and long mid-infrared cut-off wavelengths(-7.5μm).The surface morphology of host glass was characterized by scanning electron microscopy(SEM)micrograph and energy dispersive spectroscopy(EDS)tests reflect that the doped compositions are distributed into the matrix glass *** results of thermal analysis show that the glasses have good thermal properties(T>769℃).Excited by 980 am laser,an intense 1810 am fluorescence is obtained originating from the transition:~3 E→~3 Hof Tmion,accompanied by upconversion *** can be observed that 1810 nm fluorescence has the highest intensity at 1 mol%YbOand owns broad full width at half-maximum(>245 nm),the luminescence intensity of~3 F→~3 Htransition increases with rising temperature from 300 to 550 ***,the value of energy transfer efficiency shows that Ybcan transfer energy to *** fitting the attenuation curves,the lifetimes of 1810 and 474 nm emission can be acquired.

关键词： Containerless technique Lanthanum gallate glass Thermal analysis Luminescence Rare earth ions

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