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基于迭代算法的不同状态散射光场聚焦

物理学报 2024年第12期73卷 190-197页

作者：段美刚赵映左浩毅太原科技大学应用科学学院太原030024 四川大学物理学院成都610065

透过散射介质传递光学信息在生物医学、航空航天等领域具有广阔的应用前景.但是,当光通过散射介质后会引起波前畸变,导致光学信息失真.基于波前振幅调制技术是利用优化算法不断对入射光波前振幅进行调整,找到可使目标区域光强最大对应... 详细信息

透过散射介质传递光学信息在生物医学、航空航天等领域具有广阔的应用前景.但是,当光通过散射介质后会引起波前畸变,导致光学信息失真.基于波前振幅调制技术是利用优化算法不断对入射光波前振幅进行调整,找到可使目标区域光强最大对应的波前振幅分布.实验主要研究通过波前振幅调制使透过散射介质的空间光实现光聚焦,讨论在不同持续时间的散射光场中控球后卫算法与遗传算法对散射光场的调控能力.实验结果表明,在散射介质持续时间相同的情况下,控球后卫算法可以实现比遗传算法更高增强因子的聚焦点以及更均匀的多点聚焦.

关键词：散射介质波前整形聚焦振幅调制

Endoscopic polidocanol foam sclerobanding for the treatment of grade Ⅱ-Ⅲ internal hemorrhoids:A prospective,multi-center,randomized study

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World Journal of Gastroenterology 2024年第38期30卷 3326-3335页

作者： Chun-ying Qu Fei-Yu Zhang yi Zhang Ming-Ming Li Zheng-Hong Li mei-Hong Cai Lei-Ming Xu Feng Shen Wen Wang Wu-Lian Lin Feng-Yu Gao Hao Zhang Guang-Yu Chen Department of Gastroenterology&Endoscopy Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai 200092China Department of Gastroenterology The 900th Hospital of the People’s Liberation Army Joint Service Support ForceFuzhou 350025Fujian ProvinceChina Department of Endoscopy Shandong Provincial Maternal and Child Health Care Hospital Affiliated to Qingdao UniversityJinan 250014Shandong ProvinceChina Department of Endoscopy Baoshan People’s Hospital of Yunnan ProvinceBaoshan 678000Yunnan ProvinceChina Department of Gastroenterology Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai 200092China

BACKGROUND Endoscopic rubber band ligation(ERBL)is a nonsurgical technique for the treatment of symptomatic internal hemorrhoids but is limited by recurrence and post-procedural *** To evaluate satisfaction,long-term recurrence,and post-procedural pain in managing internal hemorrhoids using a combination of polidocanol foam sclerotherapy and *** This was a prospective,multicenter,randomized study.A total of 195 consecutive patients diagnosed with grade II-III internal hemorrhoids were enrolled from four tertiary hospitals and randomly divided into a cap-assisted endoscopic polidocanol foam sclerobanding(EFSB)or an ERBL *** patients were followed-up for 12 ***-based severity and post-procedural pain were assessed using a hemorrhoid severity score(HSS)and a visual analog scale(VAS).Continuous variables were reported as medians and interquartile *** One hundred and ninety-five patients were enrolled,with 98 in the EFSB *** was lower in the EFSB group than in the ERBL group at 8 weeks[4.0(3.0-5.0)vs 5.0(4.0-6.0),P=0.003]and 12-month[2.0(1.0-3.0)vs 3.0(2.0-3.0),P<0.001]of *** prolapse recurrence rate was lower in the EFSB group at 12 months(11.2%vs 21.6%,P=0.038).Multiple linear regression analysis demonstrated that EFSB treatment[B=-0.915,95%confidence interval(CI):−1.301 to−0.530,P=0.001]and rubber band number(B=0.843,95%CI:0.595-1.092,P<0.001)were negatively and independently associated with the VAS score 24 hours *** median VAS was lower in the EFSB group than in the ERBL[2.0(1.0-3.0)vs 3.0(2.0-4.0),P<0.001].CONCLUSION Cap-assisted EFSB provided long-term satisfaction and effective relief from the recurrence of prolapse and pain 24 hours post-procedure.

关键词： Internal hemorrhoids Endoscopic therapy Polidocanol foam Sclerotherapy Rubber band ligation Sclerobanding

SW220/430LV在不同温度下热-力压缩行为研究和表征建模

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复合材料学报 2024年第1期41卷 521-532页

作者：陈国涛梅志远夏奕海军工程大学舰船与海洋学院武汉430033 中国人民解放军92728部队上海200040

对S2/430LV进行热-力联合作用下压缩性能试验研究,重点揭示S2/430LV在20~180℃压缩损伤失效机制及强度/模量随温度变化规律;提出一种基于Ha-Springer模型的分段曲线拟合方法,并对强度/模量随温度变化规律进行预报。研究表明:在热-力联... 详细信息

对S2/430LV进行热-力联合作用下压缩性能试验研究,重点揭示S2/430LV在20~180℃压缩损伤失效机制及强度/模量随温度变化规律;提出一种基于Ha-Springer模型的分段曲线拟合方法,并对强度/模量随温度变化规律进行预报。研究表明:在热-力联合作用下,压缩强度和模量随着温度升高而降低,但模量保留率高于强度;随着温度增加,试样最终失效模式发生改变,在100℃之前,试样呈整体剪切失效模式,纤维束发生扭结,并伴随纤维断裂和损伤路径出现断口;但在100℃以后,最终失效模式表现为树脂基体剪切损伤,而纤维织物形态基本不变;强度和模量随温度变化规律呈“S”形趋势,其中强度-温度曲线在20~80℃为凸曲线,80~180℃则为凹曲线;模量-温度曲线在20~100℃为凸曲线,100~180℃为凹曲线;提出了一种基于Ha-Springer模型的分段曲线拟合方法,并利用Origin软件对强度/模量随温度变化规律进行预报,预报结果与试验结果高度吻合,且吻合程度优于Mahieux模型。

关键词：热-力联合压缩性能失效机制 Origin Ha-Springer模型 Mahieux模型

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城市实景模型结构化线面特征重构方法

同济大学学报（自然科学版） 2024年第1期52卷 130-136页

作者：梅熙王义曲英杰邓非中铁二院工程集团有限责任公司四川成都610031 武汉大学测绘学院湖北武汉430072

为了改善城市实景模型边缘模糊,提出了一种曲率引导的结构化线面特征重构方法。根据曲率特征将网格分割为平面、可展凹、可展凸以及不可展曲面4类,在平面分割结果内提取平面,在可展凹和可展凸分割结果内提取直线,对过度弯曲的不可展区... 详细信息

为了改善城市实景模型边缘模糊,提出了一种曲率引导的结构化线面特征重构方法。根据曲率特征将网格分割为平面、可展凹、可展凸以及不可展曲面4类,在平面分割结果内提取平面,在可展凹和可展凸分割结果内提取直线,对过度弯曲的不可展区域进行保留,最终形成包含几何特征的复合网格模型。结果表明,结合曲率信息预先设置几何特征的潜在范围,使得结构化线面特征更可靠,同时保证城市实景中复杂的树结构不被错误地提取为平面。

关键词：实景三维模型三维重建网格线特征面特征马尔科夫随机场(MRF) 简化

Erratum to“Tumor Microenvironment-Specific Chemical Internalization for Enhanced Gene Therapy of Metastatic Breast Cancer”

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Research 2024年第3期6卷 797-798页

作者： Yun Zhou Mian Yu Changjun Tie Yang Deng Junqing Wang Yunfei yi Fan Zhang Chenyi Huang Hairong Zheng Lin mei meiying Wu School of Pharmaceutical Sciences(Shenzhen) Sun Yat-sen UniversityShenzhen 518107China Paul C.Lauterbur Research Center for Biomedical Imaging Institute of Biomedical and Health EngineeringShenzhen Institutes of Advanced TechnologyChinese Academy of SciencesShenzhen 518055China Tianjin Key Laboratory of Biomedical Materials Key Laboratory of Biomaterials and Nanotechnology for Cancer ImmunotherapyInstitute of Biomedical EngineeringChinese Academy of Medical Sciences and Peking Union Medical CollegeTianjin 300192China

In the Research Article “Tumor Microenvironment-Specific Chemical Internalization for Enhanced Gene Therapy of Metastatic Breast Cancer,” the authors made an error in Fig. 6A. In Fig. 6A, the image of “pre” in the “Free Cy5-siRNA” group was misused. When incorporating the final images in Fig. 6A, another image of “24 h” in the “Free Cy5-siRNA” group was inadvertently chosen as the “Pre” image, so they appear to be remarkably similar. After the error was discovered, the authors repeated the experiments that concluded that this error did not affect the results, discussion, or conclusion of this paper. Figure 6A has now been corrected in the PDF and HTML (full text).

关键词： Internal Cancer Breast

Psychological stress impact neurotrophic factor levels in patients with androgenetic alopecia and correlated with disease progression

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World Journal of Psychiatry 2024年第10期14卷 1437-1447页

作者： yi Cheng Li-Jing Lv Yu Cui Xiao-mei Han Yan Zhang Cai-Xia Hu Department of Dermatology The Fourth Hospital of Hebei Medical UniversityShijiazhuang 050000Hebei ProvinceChina

BACKGROUND Androgenetic alopecia(AGA)is a common form of hair loss that can be influenced by psychological *** To investigate the impact of mental stress on neurotrophic factors in patients with AGA and correlate the findings with the progression of *** A total of 120 patients with AGA were analyzed in this study,which were divided into a non-stress group(n=30)and a stress group(n=90)on the basis of the presence or absence of psychological stress confirmed by Depression Anxiety Stress Scale-21 *** baseline demographic characteristics,serum cortisol levels,hair growth parameters,neurotrophic factors,and AGA progression scores between the non-stress and stress groups were *** analyses were conducted to assess the relationships among stress,neurotrophic factors,hair loss progression,and AGA *** This study revealed significantly higher cortisol levels throughout the day in the stress group than in the non-stress *** stress group exhibited lower levels of nerve growth factor,brain-derived neurotrophic factor,and glial cell linederived neurotrophic factor and higher expression levels of neurotrophin(NT)-3 and NT-4 than the non-stress *** parameters indicated lower hair diameter,decreased hair density,and more severe AGA grading in the stress group,whereas follicle count and terminal/vellus hair ratio showed no significant differences between the two *** 1 year of treatment with 5%minoxidil,efficacy was observed to be lower but AGA progression was notably more pronounced in the stress group than in the non-stress *** progression was positively correlated with high stress and NT-4 *** This study provides compelling evidence of the influence of mental stress on neurotrophic factors and its correlation with the progression of *** findings underscore the need for a comprehensive approach to the management of AGA that considers the physiological and psychosocial ***

关键词： Mental stress Neurotrophic factors Androgenetic alopecia Progression

Characteristics and genesis of groundwater salinization in coastal areas of the Lower Reaches of Oujiang Basin

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Journal of Groundwater Science and Engineering 2024年第2期12卷 190-204页

作者： mei-hui Zhang Shi-yang Zhou Dan-dan Liu ying Zhang Yu-xi Zhang Xi Chen Hui-wei Wang Bei Li Wei Kang Bing yi Wan-peng Shi Institute of Hydrogeology and Environmental Geology Chinese Academy of Geological SciencesShijiazhuang 050061China Fujian Provincial Key Laboratory of Water Cycling and Eco–Geological Processes Xiamen 361021FujianChina China University of Geosciences(Beijing) Beijing 100083China Changsha Center of Natural Resources Comprehensive Survey China Geological SurveyChangsha 410600China Hydrogeological Environmental Geological Survey Center of China Geological Survey Tianjin 071501China China University of Geosciences Wuhan 430074China

The coastal areas of the lower reaches of Oujiang River Basin are rich in groundwater ***,the unsustainable exploitation and utilization of groundwater have led to significant changes in the groundwater *** the characteristics and genesis of groundwater salinization is crucial for preventing its deterioration and ensuring sustainable *** this study,a comprehensive approach combining the ion ratio method,mineral saturation index method and multivariate statistical analysis was employed to investigate the hydrochemical characteristics and main controlling factors in the study *** findings reveal that:(1)Groundwater samples in study area exhibit a neutral to slightly alkaline *** predominant chemical types of unconfined water are HCO_(3)-Ca·Na,HCO_(3)·Cl-Na·Ca and HCO_(3)·SO_(4)-Ca·Na,while confined water mainly exhibits Cl·HCO_(3)-Na and Cl-Na types.(2)Salinity coefficients indicate an increase in salinity from unconfined to confined ***,Na^(+)and Cl^(–)concentrations show an increasing trend from mountainous to coastal areas in unconfined water,while confined water displays variability in TDS,Na^(+)and Cl^(–)concentrations.(3)Groundwater salinity is mainly influenced by water-rock interactions,including the dissolution of halite and gypsum,cation exchange,and seawater intrusion ***,human activities and carbonate dissolution contribute to salinity in unconfined *** intrusion is identified as the primary factor leading to higher salinity in confined water compared to unconfined water,with increasing cation exchange and seawater interaction observed from unconfined to confined water.

关键词： Hydrochemical Multivariate statistical analysis Seawater intrusion

Research trends in exercise therapy for the treatment of pain in postmenopausal osteoporosis over the past decade:A bibliometric analysis

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World Journal of Orthopedics 2024年第10期15卷 950-964页

作者： Zhao-Qiu Dai Xiao-Yan Gong Rong Zhang mei-Qin Jin Wei Lu Wen Wen Jie Chen Fang-Jie Lu yi-Fan Yang Lei Wang Xiao-Jin He Changshu Hospital Affiliated with Nanjing University of Chinese Medicine Changshu 215500Jiangsu ProvinceChina Affiliated Hospital of Nanjing University of Chinese Medicine Jiangsu Province Hospital of Chinese MedicineNanjing 210029Jiangsu ProvinceChina Nanjing University of Chinese Medicine Nanjing 210023Jiangsu ProvinceChina

BACKGROUND Postmenopausal osteoporosis(PMOP)is the most common form of primary osteoporosis among women,and the associated pain often drives patients to seek clinical *** studies have highlighted the unique clinical benefits of exercise therapy(ET)in alleviating PMOP-related ***,bibliometric analyses examining collaboration,development trends,and research frontiers in the field of ET for PMOP pain remain *** To explore the research trends in ET for pain treatment in PMOP patients over the past *** All scholarly works were meticulously sourced from the Science Citation Index-Expanded within the prominent Web of Science Core *** the capabilities of CiteSpace 6.2.R5,we conducted a thorough analysis of publications,authors,frequently cited scholars,contributing nations,institutions,journals of significant citation,comprehensive references,and pivotal ***,our examination explored keyword cooccurrences,detailed timelines,and periods of heightened citation *** comprehensive search,from 2014 through 2023,was completed within a single day,on October 11,*** In total,2914 articles were ultimately included in the *** was a rapid increase in annual publication output in 2015,followed by stable growth in subsequent ***,Michael L,is the most prolific author,whereas Ware JE has the most *** United States’global influence is significant,surpassing all other *** University of California System and Harvard University are the most influential academic institutions.J Bone Joint Surg Am is the most influential journal in this field.“Spinal cord injury”is the keyword that has garnered the most attention from *** developmental pattern in this field is characterized by interdisciplinary fusion,with different disciplines converging to drive *** The academic development of the field of ET for pain in PMOP has matured and stabili

关键词： Exercise therapy Pain Postmenopausal osteoporosis CiteSpace Bibliometric analysis Web of Science

Association of cardiometabolic multimorbidity with all-cause and cardiovascular disease mortality among Chinese hypertensive patients

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Journal of Geriatric Cardiology 2024年第2期21卷 211-218页

作者： Luo-Xi XIAO Zi-Yu WANG Jiang-Tao LI Hai-mei WANG yi-Ming HAO Pan ZHOU Yu-Lin HUANG Qiu-Ju DENG Yong-Chen HAO Na YANG Li-Zhen HAN Zhao YANG Ping-Ping JIA Yue QI Jing LIU Center for Clinical and Epidemiologic Research Beijing Anzhen HospitalCapital Medical UniversityBeijing Institute of HeartLung and Blood Vessel DiseasesBeijing Municipal Key Laboratory of Clinical EpidemiologyBeijingChina

BACKGROUND Hypertension usually clusters with multiple ***,the association between cardiometabolic multimorbidity(CMM)and mortality in hypertensive patients is *** study aimed to investigate the association between CMM and all-cause and cardiovascular disease(CVD)mortality in Chinese patients with *** The data used in this study were from the China National Survey for Determinants of Detection and Treatment Status of Hypertensive Patients with Multiple Risk Factors(CONSIDER),which comprised 5006 participants aged 19–91 *** was defined as the presence of one or more of the following morbidities:diabetes mellitus,dyslipidemia,chronic kidney disease,coronary heart disease,and *** proportional hazard models were used to calculate the hazard ratios(HR)with 95%CI to determine the association between the number of CMMs and both all-cause and CVD *** Among 5006 participants[mean age:58.6±10.4 years,50%women(2509 participants)],76.4%of participants had at least one *** mortality rate was 4.57,4.76,8.48,and 16.04 deaths per 1000 person-years in hypertensive patients without any comorbidity and with one,two,and three or more morbidities,*** the fully adjusted model,hypertensive participants with two cardiometabolic diseases(HR=1.52,95%CI:1.09–2.13)and those with three or more cardiometabolic diseases(HR=2.44,95%CI:1.71–3.48)had a significantly elevated risk of all-cause *** findings were similar for CVD mortality but with a greater increase in risk *** In this study,three-fourths of hypertensive patients had *** with two or more comorbidities was associated with a significant increase in the risk of all-cause and cardiovascular mortality among hypertensive patients,suggesting more intensive treatment and control in this high-risk patient group.

关键词： hypertensive patients morbidity