检索结果-南通市图书馆

Compression Effect of Ultrashort Pulse in Far Infrared Waveguide Free Electron Laser

在线全文

学校读者我要写书评

暂无评论

Chinese Physics Letters 1995年第12期12卷 720-723页

作者： hu Suxing FU Ensheng Shanghai Institute of Optics and Fine Mechanics Academia SinicaShanghai 201800

Compression mechanism of ultrashort pulse in far infrared waveguide free electron laser driven by radio frequency linear accelerator was *** a pertinent waveguide gap b,when the original phase velocity of the electron bunch ensures the positive gain and the refractivity of the optical pulse monotone increasing along the dative slip distance,the longitudinal length of optical pulse will be continuously shortened so that the pulse power increases quickly until saturation *** offset the"lethargy"effect,an optimal cavity detuningΔL_(c) has been accurately determined.

关键词： waveguide tuning Waveguide

Dithieno[a,e]pentalene Based Conjugated Polymers： Synthesis and Characterization

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Chemistry 2013年第11期31卷 1404-1408页

作者： Chao hu Qing Zhang School of Chemistry and Chemical Engineering Shanghai Jiao Tong University Shanghai 200240 China

The concept of introducing n-conjugated but anti-aromatic repeating units into conjugated polymers has been explored. The thermal stability, optical and electrochemical properties of dithieno[a,e]pentalenes （DTP） based polymers have been studied. The effect of introducing electron withdrawing repeating units into DTP based poly- mer on the physical properties of polymer has also been investigated. The new polymers showed broad absorption in visible and near-infrared region.

关键词： pentalene conjugated polymer low-bandgap polymer anti-aromatic

Aggregation of Gold Nanoparticles and DNA Damage by Atomic Force Microscopy

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Wuhan University of Technology(Materials Science) 2014年第1期29卷 180-184页

作者：胡善洲刘鹏 hu Yu Department of Chemistry School of Science Wuhan University of Technology Department of Quality Assurance of huBei Tobacco Industry Corporation

The plasmid DNA binding and cleavage activities with gold nanoparticles(Au-NPs) were investigated by the integrated tools of UV-vis spectroscopy, atomic force microscopy(AFM), and DNA electrophoresis. The results showed that the absorbance of Au-NPs decreased at 520 nm and a new absorption peak at 570 nm was found, as the DNA concentration increased, which indicated the particle aggregation. AFM experiments showed that DNA-induced particle aggregation originated from the strong interactions between DNA and Au-NPs, that is, the adsorption of DNA onto the Au-NPs surface would result in particle aggregation. After a short period of time, the Au-NPs were easier to aggregate in the presence of the higher concentration of DNA. At the early stage of incubation, the DNA double helix conformation was substantially changed by particles. The electrophoresis manifested the absorption and damage appeared on the native DNA molecules. With a longer treating time, the molecules were broken into fragments. The DNA damage was deemed to be a gradual process. The nonspecific interactions between DNA and Au-NPs resulted in the binding of DNA to the Au-NPs surface. Consequently, not only Au-NPs were aggregated but also DNA was damaged.

关键词： plasmid DNA gold nanoparticles damage aggregation AFM

Prognostic value of preoperative weight loss-adjusted body mass index on survival after esophagectomy for esophageal squamous cell carcinoma

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2020年第8期26卷 839-849页

作者： Han-Lu Zhang Yu-Shang Yang Jia-Nan Duan Qi-Xin Shang Song-Lin He Yi-Min Gu wei-Peng hu Wen-Ping Wang Yang hu Yun Wang Yong Yuan Long-Qi Chen Department of Thoracic Surgery West China Hospital of Sichuan UniversityChengdu 610041Sichuan ProvinceChina Department of Ophthalmology West China Hospital of Sichuan UniversityChengdu 610041Sichuan ProvinceChina Department of Thoracic and Cardiovascular Surgery the Second People's Hospital of ChengduChengdu 610017Sichuan ProvinceChina

BACKGROUND The impact of body mass index(BMI)on survival in patients with esophageal squamous cell carcinoma(ESCC)undergoing surgery remains ***,a definition of clinically significant BMI in patients with ESCC is *** To explore the impact of preoperative weight loss(PWL)-adjusted BMI on overall survival(OS)in patients undergoing surgery for *** This retrospective study consisted of 1545 patients who underwent curative resection for ESCC at West China Hospital of Sichuan University between August 2005 and December *** relationship between PWL-adjusted BMI and OS was examined,and a multivariate analysis was performed and adjusted for age,sex,TNM stage and adjuvant *** Trends of poor survival were observed for patients with increasing PWL and decreasing *** with BMI≥20.0 kg/m2 and PWL<8.8%were classified into Group 1 with the longest median OS(45.3 mo).Patients with BMI<20.0 kg/m2 and PWL<8.8%were classified into Group 2 with a median OS of 29.5 *** with BMI≥20.0 kg/m2 and PWL≥8.8%(HR=1.9,95%CI:1.5-2.5),were combined into Group 3 with a median OS of 20.1 *** in the three groups were associated with significantly different OS(P<0.05).In multivariate analysis,PWL-adjusted BMI,TNM stage and adjuvant therapy were identified as independent prognostic *** PWL-adjusted BMI has an independent prognostic impact on OS in patients with ESCC undergoing *** might be an indicator for patients with PWL<8.8%rather than≥8.8%.

关键词： Esophageal neoplasms Body mass index Body weight change Survival Surgery Nutrition status

Frequency-time Domain Shielding Effectiveness of Materials and Their Strong Electromagnetic Field Test

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

高电压技术 2013年第10期39卷 2398-2402页

作者： ZHANG Long wei Guanghui FAN Lisi hu Xiaofeng ZHAO Yang ZHANG Yongqiang National Key Laboratory of Science and Technology on Electromagnetic Environment Effects Mechanical Engineering College Shijiazhuang 050003 China Shijiazhuang Flying College of the PLA Air Force Shijiazhuang 050081 China

To describe the shielding ability of materials accurately and comprehensively,the frequency-domain and time-domain shielding effectiveness(SE) of material is *** relevance between them was analyzed based on the minimum phase method,and the time-domain SE can be derived from frequency-domain *** SE of an energy selective surface(ESS) made of a novel material is investigated,and the relationship between SE and radiation field intensity are *** results show that not only material,but also the intensity of radiation electric field shows influence on SE in its frequency; for some materials,the dependence of SE on radiation electric field intensity needs to be ***,it is necessary to research on the SE of shielding material in high-intensity electromagnetic environment.

关键词：新型材料屏蔽效能磁场测试时间域频率强电电场强度遮蔽能力

Generalized Bargmann Representation of Spin Coherent State

在线全文

学校读者我要写书评

暂无评论

Communications in Theoretical Physics 2004年第4期41卷 537-540页

作者： FANHong-Yi CHENJun-hu DepartmentofPhysics ShanghaiJiaoTongUniversityShanghai200030China DepartmentofMaterialScienceandEngineering UniversityofScienceandTechnologyofChinaHefei230026China

Based on the conclusion that the generalized Bargmann representation of a two-mode Fock state is a two-variable Hermite polynomial function /Hong-Yi Fan and Jun-hua Chen,***.A303(2002)311] we derive the generalized Ba... 详细信息

关键词： spin coherent state generalized Bargmann representation Hermite polynomials

The enigmatic processing and secretion of interleukin-33

在线全文

学校读者我要写书评

暂无评论

Cellular & Molecular Immunology 2010年第4期7卷 260-262页

作者： weihua Zhao Zhiqing hu Department of Microbiology and Immunology Showa University School of MedicineTokyoJapan

Interleukin-33(IL-33)is the most attractive novel cytokine identified as an IL-1 family ***-33 was first named NF-HEV(nuclear factor from high endothelial venules),as it was known to interact with nuclear chromatin although its exact intracellular functions are still to be ***-33 is now recognized as the specific ligand for the orphan IL-1 receptor family member ST2 and to be involved in polarization of T cells towards T helper 2 cell phenotype and in activation of mast cells,bosophils,eosinophils and natural killer *** is essential for IL-33 to be extracellularly released in order to bind to the ST2 receptor and consequently play a crucial role in inflammatory,infectious and autoimmune ***,like the IL-1 family members,IL-1b and IL-18,IL-33 mRNA is translated without a signal sequence for ***,IL-33 cannot be released by the processing and secretion mechanism shared by IL-1b and IL-18 as IL-33 is not a substrate of caspase-1 and does not require proteolysis for *** contrast,IL-33 can be inactivated by apoptotic ***,IL-33 is proposed to be released as an alarmin from necrotic cells but to be deleted during *** the known autocrine,paracrine,intracrine,juxtacrine and retrocrine mechanisms of cellular interaction with cytokines,release by necrotic cells is another pathway for a cytokine to display its function,which we suggest might be called‘necrocrine’.This mini review summarizes recent progress of how IL-33 displays potential immunoregulatory roles with a particular focus on its enigmatic production.

关键词： Interleukin-33 Interleukin-1 family Caspase-1 Intracrine Necrocrine

Antagonistic effects of extracts from Artemisia rupetris L. and Leontopodium leontopodioides to CC chemokine receptor 2b(CCR2b)

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Natural Medicines 2016年第5期14卷 363-369页

作者： YU Qin-wei hu Jie WANG Hao CHEN Xin ZHAO Fang GAO Peng YANG Qiu-Bin SUN Dan-Dan ZHANG Lu-Yong YAN Ming Jiangsu Key Laboratory of Drug Screening China Pharmaceutical University Department of Natural Medicinal Chemistry China Pharmaceutical University School of Life Science and Technology China Pharmaceutical University School of Traditional Chinese Medicine China Pharmaceutical University Key Laboratory of Drug Quality Control and Pharmacovigilance (China Pharmaceutical University) Ministry of Education

The present study was designed to establish a suitable assay to explore CCR2 b receptor antagonists from the natural products of Artemisia rupetris and Leontopodium leontopodioides. An aequorin assay was developed as a cell-based assay suitable for 384-well microplate and used for screening CCR2 b receptor antagonists from natural products. Through establishing suitable conditions, the assay was shown to be suitable for screening of CCR2 b receptor antagonists. Seven compounds were identified in preliminary screening. Five of them showed evident dose-response relationship in secondary screening. The structure–activity relationship study suggested that 7-position hydroxyl group of flavonoids was necessary, a polar group should be introduced on the 3-position, and the substituents on 2-position benzene ring of flavonoids have little influence on the potentency of the inhibition activity on CCR2 b receptor. The ortho-position dihydroxyl structure in quinic acid compounds may be important. In conclusion, Compounds HR-1, 5, 7, and AR-20, 35 showed activity as antagonist of CCR2 b receptor, which shed lights on the development of novel drugs as CCR2 b receptor antagonists for preventing inflammation related diseases.

关键词： CCR2b antagonist Inflammation Aequorin assay Artemisia rupetris Leontopodium leontopodioides

How the electron-deficient Cp ligand facilitates Rh-catalyzed annulations with alkynes

在线全文

学校读者我要写书评

暂无评论

Organic Chemistry Frontiers 2022年第4期9卷 979-988页

作者： Han Gao Lingfei hu Yanlei hu Xiangying Lv Yan-BoWu Gang Lu School of Chemistry and Chemical Engineering Key Laboratory of Colloid and Interface ChemistryMinistry of EducationShandong UniversityJinanShandong 250100China Key Lab for Materials of Energy Conversion and Storage of Shanxi Province and Key Lab of Chemical Biology and Molecular Engineering of Ministry of Education Institute of Molecular ScienceShanxi UniversityTaiyuanShanxi 030006China

The mechanism and origin of the Cp^(X) ligand effects on Rh-catalyzed annulations with alkynes were inves-tigated using DFT calculations and the approach of energy decomposition analysis(EDA).The results reveal that the alkyne migratory insertion is the rate-determining step for the reactions with both acetanilide and 2-phenyl-2-propanol substrates.

关键词： catalyzed deficient insertion