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Research trends in exercise therapy for the treatment of pain in postmenopausal osteoporosis over the past decade:A bibliometric analysis

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World Journal of Orthopedics 2024年第10期15卷 950-964页

作者： Zhao-Qiu Dai Xiao-Yan Gong Rong Zhang mei-qin jin Wei Lu Wen Wen Jie Chen Fang-Jie Lu Yi-Fan Yang Lei Wang Xiao-jin He Changshu Hospital Affiliated with Nanjing University of Chinese Medicine Changshu 215500Jiangsu ProvinceChina Affiliated Hospital of Nanjing University of Chinese Medicine Jiangsu Province Hospital of Chinese MedicineNanjing 210029Jiangsu ProvinceChina Nanjing University of Chinese Medicine Nanjing 210023Jiangsu ProvinceChina

BACKGROUND Postmenopausal osteoporosis(PMOP)is the most common form of primary osteoporosis among women,and the associated pain often drives patients to seek clinical *** studies have highlighted the unique clinical benefits of exercise therapy(ET)in alleviating PMOP-related ***,bibliometric analyses examining collaboration,development trends,and research frontiers in the field of ET for PMOP pain remain *** To explore the research trends in ET for pain treatment in PMOP patients over the past *** All scholarly works were meticulously sourced from the Science Citation Index-Expanded within the prominent Web of Science Core *** the capabilities of CiteSpace 6.2.R5,we conducted a thorough analysis of publications,authors,frequently cited scholars,contributing nations,institutions,journals of significant citation,comprehensive references,and pivotal ***,our examination explored keyword cooccurrences,detailed timelines,and periods of heightened citation *** comprehensive search,from 2014 through 2023,was completed within a single day,on October 11,*** In total,2914 articles were ultimately included in the *** was a rapid increase in annual publication output in 2015,followed by stable growth in subsequent ***,Michael L,is the most prolific author,whereas Ware JE has the most *** United States’global influence is significant,surpassing all other *** University of California System and Harvard University are the most influential academic institutions.J Bone Joint Surg Am is the most influential journal in this field.“Spinal cord injury”is the keyword that has garnered the most attention from *** developmental pattern in this field is characterized by interdisciplinary fusion,with different disciplines converging to drive *** The academic development of the field of ET for pain in PMOP has matured and stabili

关键词： Exercise therapy Pain Postmenopausal osteoporosis CiteSpace Bibliometric analysis Web of Science

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The gut-eye axis:from brain neurodegenerative diseases to age-related macular degeneration

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Neural Regeneration Research 2025年第10期20卷 2741-2757页

作者： Qianzi jin Suyu Wang Yujia Yao qin Jiang Keran Li Department of Ophthalmology The Affiliated Eye Hospital of Nanjing Medical UniversityNanjingJiangsu ProvinceChina The Fourth School of Clinical Medicine Nanjing Medical UniversityNanjingJiangsu ProvinceChina

Age-related macular degeneration is a serious neurodegenerative disease of the retina that significantly impacts ***,the specific pathogenesis remains unclear,and effective early treatment options are consequently *** microbiome is defined as a large ecosystem of microorganisms living within and coexisting with a *** intestinal microbiome undergoes dynamic changes owing to age,diet,genetics,and other *** dysregulation of the intestinal flora can disrupt the microecological balance,resulting in immunological and metabolic dysfunction in the host,and affecting the development of many *** recent decades,significant evidence has indicated that the intestinal flora also influences systems outside of the digestive tract,including the ***,several studies have demonstrated the critical role of the gut-brain axis in the development of brain neurodegenerative diseases,including Alzheimer’s disease and Parkinson’s ***,the role of the“gut-eye axis”has been confirmed to play a role in the pathogenesis of many ocular ***,age-related macular degeneration and many brain neurodegenerative diseases have been shown to share several risk factors and to exhibit comparable *** such,the intestinal flora may play an important role in age-related macular *** the above context,the present review aims to clarify the gut-brain and gut-eye connections,assess the effect of intestinal flora and metabolites on age-related macular degeneration,and identify potential diagnostic markers and therapeutic ***,direct research on the role of intestinal flora in age-related macular degeneration is still relatively limited,while studies focusing solely on intestinal flora are insufficient to fully elucidate its functional role in age-related macular ***-on-a-chip technology has shown promise in clarifying the gut-eye interactions,while integrating analysis of the inte

关键词： age-related macular degeneration biological agents blinding eye disease dietary nutrition fecal microbial transplantation gut-eye axis intestinal flora metabolite microecology neurodegenerative disease

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Enhancing m^(6)A modification in the motor cortex facilitates corticospinal tract remodeling after spinal cord injury

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Neural Regeneration Research 2025年第6期20卷 1749-1763页

作者： Tian qin Yuxin jin Yiming qin Feifei Yuan Hongbin Lu Jianzhong Hu Yong Cao Chengjun Li Department of Spine Surgery and Orthopedics Xiangya HospitalCentral South UniversityChangshaHunan ProvinceChina Key Laboratory of Organ Injury Aging and Regenerative Medicine of Hunan ProvinceChangshaHunan ProvinceChina National Clinical Research Center for Geriatric Disorders Xiangya HospitalCentral South UniversityChangshaHunan ProvinceChina Department of Sports Medicine Xiangya HospitalCentral South UniversityChangshaHunan ProvinceChina

Spinal cord injury typically causes corticospinal tract disruption. Although the disrupted corticospinal tract can self-regenerate to a certain degree, the underlying mechanism of this process is still unclear. N6-methyladenosine(m^(6)A) modifications are the most common form of epigenetic regulation at the RNA level and play an essential role in biological processes. However, whether m^(6)A modifications participate in corticospinal tract regeneration after spinal cord injury remains unknown. We found that expression of methyltransferase 14 protein(METTL14) in the locomotor cortex was high after spinal cord injury and accompanied by elevated m^(6)A levels. Knockdown of Mettl14 in the locomotor cortex was not favorable for corticospinal tract regeneration and neurological recovery after spinal cord injury. Through bioinformatics analysis and methylated RNA immunoprecipitation-quantitative polymerase chain reaction, we found that METTL14 regulated Trib2 expression in an m^(6)A-regulated manner, thereby activating the mitogen-activated protein kinase pathway and promoting corticospinal tract regeneration. Finally, we administered syringin, a stabilizer of METTL14, using molecular docking. Results confirmed that syringin can promote corticospinal tract regeneration and facilitate neurological recovery by stabilizing METTL14. Findings from this study reveal that m^(6)A modification is involved in the regulation of corticospinal tract regeneration after spinal cord injury.

关键词： corticospinal tract remodeling epigenetic regulations locomotor cortex m^(6)A modification methyltransferase 14 protein(METTL14) mitogen-activated protein kinase neural regeneration spinal cord injury syringin TRIB2

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政府购买社会服务背景下的工会工作

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北京市工会干部学院学报 2014年第3期29卷 4-7页

作者：覃妹锦广西壮族自治区总工会干部学校广西南宁530031

当前各级工会认真贯彻落实中央关于加强和创新社会管理的重要部署,依法代表职工和维护职工合法权益,推动构建和谐劳动关系,切实维护职工队伍稳定,为进一步提升工会参与社会管理工作水平奠定了良好基础。2013年9月30日,国务院公布了《关... 详细信息

当前各级工会认真贯彻落实中央关于加强和创新社会管理的重要部署,依法代表职工和维护职工合法权益,推动构建和谐劳动关系,切实维护职工队伍稳定,为进一步提升工会参与社会管理工作水平奠定了良好基础。2013年9月30日,国务院公布了《关于政府向社会力量购买服务的指导意见》,面对社会管理和服务新形势,工会应积极探索工会工作的创新及社会管理和社会服务之间的途径。

关键词：政府购买社会服务工会工作

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Stepwise assembly to construct stable copper(I) cluster-based circularly polarized luminescent MOFs

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Science China Chemistry 2025年

作者： jing-Wen Xie Meng-Ting Wang Yan jin Si Li Jian-Hua qin Shuang-Quan Zang Tomas C.W.Mak College of Chemistry Henan Key Laboratory of Crystalline Molecular Functional Materials Zhengzhou University College of Chemistry and Chemical Engineering Luoyang Normal University Department of Chemistry The Chinese University of Hong Kong

Circularly polarized luminescence （CPL） materials have been extensively studied in recent years owing to their widespread applications in 3D display,optical storage,optical anti-counterfeiting,and biological imaging,***（I） clusters have emerged as a promising candidate for CPL materials,driven by their cost-effectiveness,superior luminescent properties,precise structure,and low ***,the poor environmental stability of copper（I） clusters renders their synthesis and preservation challenging,thereby significantly impeding their ***,we have designed and synthesised a chiral double-coordinated ligand in order to construct copper（I） cluster nodes that can be further *** anticipated,by utilizing stepwise assembly strategy,a Cu4cluster node co-modified by chiral alkynyl ligands and triphenylphosphine was further assembled with Cd2+ions to obtain 2D layers structure,L/*** L/D-Cu4-Cd exhibits excellent stability and optical properties,including bright yellow emission,solvent-responsive luminescence,and CPL activity with a maximum glumup to 2.0×10-3,which shows potential applications in the WLED and *** interestingly,the material also exhibits deflection ability towards different wavelengths of linearly polarized light,showing certain potential in the preparation of circular polarizer.

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柠檬酸铝结构形态及其对部分水解聚丙烯酰胺柠檬酸铝体系交联性质的影响

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石油大学学报（自然科学版） 2004年第4期28卷 125-128,133页

作者：林梅钦宋锦红李明远吴肇亮石油大学化学化工学院北京102249

通过分析27Al核磁共振波谱、自旋晶格弛豫时间,结合数字拟合方法、渗析法和原子吸收分光光度法,对柠檬酸铝的形态结构及其影响因素进行了研究;利用转变压法研究了pH值对部分水解聚丙烯酰胺与柠檬酸铝体系交联过程的影响。结果表明,柠檬... 详细信息

通过分析27Al核磁共振波谱、自旋晶格弛豫时间,结合数字拟合方法、渗析法和原子吸收分光光度法,对柠檬酸铝的形态结构及其影响因素进行了研究;利用转变压法研究了pH值对部分水解聚丙烯酰胺与柠檬酸铝体系交联过程的影响。结果表明,柠檬酸铝溶液中pH值增加时,Al(1)化学位移减少;pH值降低时,Al(2)化学位移减少。在柠檬酸铝溶液中存在两种形态的铝,一种是分子态,另一种是胶态。pH值增加时,分子态铝的量减少,而胶态铝的量增加。对部分水解聚丙烯酰胺与柠檬酸铝形成低聚合物浓度体系交联过程的研究表明,该反应所需柠檬酸铝为最佳形态结构时,溶液的pH值为5.0～7.0。

关键词：柠檬酸铝部分水解聚丙烯酰胺低聚聚合物浓度交联降低渗析 pH值溶液研究

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Interval standard neural network models for nonlinear systems

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2006年第4期7卷 530-538页

作者： LIU mei-qin School of Electrical Engineering Zhejiang University Hangzhou 310027 China

A neural-network-based robust control design is suggested for control of a class of nonlinear systems. The design ap- proach employs a neural network, whose activation functions satisfy the sector conditions, to approximate the nonlinear system. To improve the approximation performance and to account for the parameter perturbations during operation, a novel neural network model termed standard neural network model (SNNM) is proposed. If the uncertainty is bounded, the SNNM is called an interval SNNM (ISNNM). A state-feedback control law is designed for the nonlinear system modelled by an ISNNM such that the closed-loop system is globally, robustly, and asymptotically stable. The control design equations are shown to be a set of linear matrix inequalities (LMIs) that can be easily solved by available convex optimization algorithms. An example is given to illustrate the control design procedure, and the performance of the proposed approach is compared with that of a related method reported in literature.

关键词： Interval standard neural network model (ISNNM) Linear matrix inequality (LMI) Nonlinear system Asymptotic stability Robust control

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Baculovirus-expressed FAdV-4 penton base protein protects chicken against hepatitis-hydropericardium syndrome

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Journal of Integrative Agriculture 2019年第11期18卷 2598-2604页

作者： ZHANG Jun-qin WEI Yan-ming HUANG Kun SUN Xiao-mei ZOU Zhong jin mei-lin State Key Laboratory of Agricultural Microbiology Huazhong Agricultural UniversityWuhan 430070P.R.China College of Veterinary Medicine Huazhong Agricultural UniversityWuhan 430070P.R.China Key Laboratory of Development of Veterinary Diagnostic Products Ministry of AgricultureWuhan 430070P.R.China

Hepatitis-hydropericardium syndrome(HHS)is an infectious disease caused by fowl adenovirus serotype 4(FAdV-4).Several structural and non-structural proteins of FAdV-4 have been expressed in Escherichia coli and baculovirus expression system to develop candidate subunit ***,the protective efficiency of baculovirus-expressed penton base protein has not been *** this study,two recombinant capsid proteins,penton base and fiber-2,were *** then,penton base and fiber-2 were administrated alone or together to specific pathogen-free(SPF)chickens at 14 days of life and boosted at 28 days of *** 42 days of life,the immunized groups and the control group were challenged with FAdV-4 virulent *** show that inoculating penton base or penton base+fiber-2 provided 100%protection to the *** groups vaccinated with the recombinant protein produced detectable antibodies and showed no apparent ***,baculovirus-expressed penton base protein is a promising candidate subunit vaccine.

关键词： fowl adenovirus serotype 4 hepatitis-hydropericardium syndrome penton base subunit vaccine baculovirus expression system

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Effect on Intensity Correlation Time by Input Signal in a Single-Mode Laser with Bias Signal Modulation

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Communications in Theoretical Physics 2005年第4X期44卷 638-642页

作者： CHEN Li-mei CAO Li WU Da-jin GE Guo-qin Department of Physics Shenzhen University Shenzhen 518060 China State Key Laboratory of Laser Technology Huazhong University of Science and Technology Wuhan 430074 China Department of Physics Huazhong University of Science and Technology Wuhan 430074 China CCAST (World Laboratory) P.O. Box 8730 Beijing 100080 China

The effect on intensity correlation time T by input signal is studied for gain-noise model of a single-mode laser driven by colored pump noise and colored quantum noise with colored cross-correlation with a bias signal modulation in this paper. By using the linear approximation method, we detect that there exists maximum （i.e., resonance） in the curve of the intensity correlation time T upon bias current io when the noise correlation coefficient λ is positive; and there exists minimum （i.e., suppression） in the T-io curve when λ is negative. And whenλ is zero, T increases monotonously with increasing io. Furthermore, the curve of T upon the signal frequency Ω is also studied. Our study shows that no matter what the value of λ is, there exists minimum （i.e., suppression） in the T-Ω curve.

关键词： intensity correlation time bias signal modulation linear approximation method

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Noether-Type Symmetries and Associated Conservation Laws of Some Systems of Nonlinear PDEs

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Communications in Theoretical Physics 2009年第3期51卷 495-498页

作者： mei Jian-qin Department of Applied Mathematics Dalian University of Technology Dalian 116024 China

The algorithm for constructing conservation laws of Euler Lagvange type equations via Noether-type symmetry operators associated with partial Lagrangian has been presented. As applications, many new conservation laws ... 详细信息

关键词： Lie-Backlund Noether-type symmetries conservation law coupled integrable dispersionless equations coupled wave equations

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