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玻璃体切除术后白内障患者的手术方式选择

国际眼科杂志 2019年第5期19卷 775-777页

作者：宋美娇张辉吉林大学第二医院白内障科中国吉林省长春市130041

玻璃体切除手术会加速白内障的发生与发展,白内障手术在玻璃体切除术后患者比在未行玻璃体切除的眼中具有更高的风险和并发症,其手术方式的选择以及术中的操作对于眼科医生具有一定挑战。相比于无灌注下的玻璃体切除术后白内障手术,25G... 详细信息

玻璃体切除手术会加速白内障的发生与发展,白内障手术在玻璃体切除术后患者比在未行玻璃体切除的眼中具有更高的风险和并发症,其手术方式的选择以及术中的操作对于眼科医生具有一定挑战。相比于无灌注下的玻璃体切除术后白内障手术,25G灌注下行白内障超声乳化术对于维持眼压,稳定前房,减少术中及术后并发症效果良好,是目前玻璃体切除术后白内障患者的首选手术方式。

关键词：玻璃体切除术白内障超声乳化术 25G灌注

Investigations of an enclosed annular rotor-stator system with LES method

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Science China(Physics,Mechanics & Astronomy) 2018年第11期61卷 50-60页

作者： Zhe jiao song Fu School of Aerospace Engineering Tsinghua University

In this study, the flows in an enclosed annular rotor-stator system with the Reynolds number ranging from 0.75×105 to 3.75×105 and an aspect ratio of 36.5 are investigated using the LES method. Few studies have explored such a rotor-stator system with this aspect ratio and the flow structure on the rotor side. The mean flow structure varies from a torsional Couette type to a Batchelor type as the Reynolds number increases. The onset of the instability in the B?dewadt layer adjacent to the stator is delayed,whereas it is promoted in the Ekman layer adjacent to the rotor. Both the layers demonstrate rich spiral structures. Turbulent spirals are observed to occur at the rotor disk side that also generates TS-wave-like(Tollmien-Schlichting) structures between adjacent spiral arms. Further, the turbulence at the stator is complex and interesting. Statistically, the turbulence is highly anisotropic near both the rotating and nonrotating disks, which is depicted by the Reynolds stresses.

关键词： rotating flow rotor-stator system large eddy simulation anisotropic turbulence Ekman-B6dewadt layers

Lirex： A Package for Identification of LongInverted Repeats in Genomes

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Genomics, Proteomics & Bioinformatics 2017年第2期15卷 141-146页

作者： Yong Wang jiao-mei Huang Institute of Deep-Sea Science and Engineering Chinese Academy of Sciences Sanya 572000 China

Long inverted repeats(LIRs) are evolutionarily and functionally important structures in genomes because of their involvement in RNA interference, DNA recombination, and gene duplication. Identification of LIRs is highly complicated when mismatches and indels between the repeats are permitted. Long inverted repeat explorer(Lirex) was developed and introduced in this report. Written in Java, Lirex provides a user-friendly interface and allows users to specify LIR searching criteria, such as length of the region, as well as pattern and size of the repeats. Recombinogenic LIRs can be selected on the basis of mismatch rate and internal spacer size from identified LIRs. Lirex, as a cross-platform tool to identify LIRs in a genome, may assist in designing following experiments to explore the function of LIRs. Our tool can identify more LIRs than other LIR searching tools. Lirex is publicly available at http://124.***.219.129/Lirex.

关键词： Lirex Inverted repeats Recombination Stem-loop Mismatch rate

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非静水压作用下石膏电学性质的理论研究

原子与分子物理学报 2025年第6期42卷 129-135页

作者：周梅吴雷罗小松何宗润贵州民族大学物理与机电工程学院贵阳550025 重庆大学能源与动力工程学院重庆400044

地球内部广泛存在着差应力,这些外在因素的存在影响着矿物的性质,而矿物的电学性质与结构相变息息相关.为了更加了解地球内部结构与动力学过程,采用第一性原理方法,在等效平衡压0~10 GPa范围内计算地球内部浅层矿物石膏在静水压和非静... 详细信息

地球内部广泛存在着差应力,这些外在因素的存在影响着矿物的性质,而矿物的电学性质与结构相变息息相关.为了更加了解地球内部结构与动力学过程,采用第一性原理方法,在等效平衡压0~10 GPa范围内计算地球内部浅层矿物石膏在静水压和非静水压条件下的电学性质.计算结果表明:静水压和非静水压条件下无水石膏的密度和带隙变化基本一致,但二水石膏的密度和带隙在非静水压为6 GPa附近发生突变,这可能是由于非静水压环境使晶体结构更容易发生畸变,更有利于水分子氢键网络的重新排列和CaSO_(4)层间结构的塌缩,因此非静水压下可能更加有利于二水石膏在高温高压下的脱水反应.这对理解地幔中矿物的脱水和储水产生重大的影响,为理解地幔中矿物的脱氢和储水提供理论依据.

关键词：差应力石膏电学性质第一性原理

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Analysis of the anti-T2DM components in dichloromethane fraction of Schisandra sphenanthera and its mechanism

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Traditional Medicine Research 2025年第1期10卷 27-43页

作者： Shi-Bo Feng Hai-Hui Jiang Hui-Li Kang Yi Jiang Hua-Wei Zhang Xiao-mei song Yu-Ze Li Wen-Li Huang Dong-Dong Zhang Chong Deng School of Pharmacy Shaanxi University of Chinese MedicineXianyang 712046China School of Pharmacy and Shaanxi Qinling Application Development and Engineering Center of Chinese Herbal Medicine Shaanxi University of Chinese MedicineXianyang 712046China Key Laboratory for Research and Development of“Qin Medicine”of Shaanxi Administration of Traditional Chinese Medicine Xianyang 712046China Shaanxi Key Laboratory of Research and Application of“Taibai Qi Yao” Xianyang 712046China

Background:The type 2 diabetes mellitus(T2DM)pharmacodynamic study of various parts of Schisandra sphenanthera was conducted in the previous stage,and it was found that dichloromethane extracted part(SDP)had a significant hypoglycemic ***,the components of SDP were analyzed,and the specific mechanism of its anti-T2DM was ***:We used a high-fat,high-sugar diet in combination with streptozotocin to induce a T2DM rat model,and the model rats were divided into two groups according to body weight and blood ***,oral glucose tolerance test,fasting blood glucose,low density lipoprotein cholesterol,superoxide dismutase,insulin,glycated hemoglobin,total cholesterol,nonesterified free fatty acids,alanine aminotransferase,high-density lipoprotein cholesterol,aspartate aminotransferase,malondialdehyde,and glutathione peroxidase were measured,organ indices were calculated,and pathological sections of pancreas and liver were *** 16S rRNA V3–V4 region of intestinal flora was sequenced to explore the effect of SDP on biochemical indicators and intestinal *** on the above indicators,the anti-T2DM mechanism of SDP in Schisandra sphenanthera was ***:After six weeks of administration,the biochemical indices of diabetic rats were diminished compared to the control *** SDP could significantly increase the gut microbialα-diversity index,resulting in significant changes in the flora of T2DM rats,with increased richness and diversity,reduced harmful flora,and significantly back-regulated the levels of acetic acid,propionic acid,and butyric ***:SDP can improve the symptoms associated with elevated blood glucose,dyslipidemia,elevated fasting insulin levels,and damaged glucose tolerance in *** against T2DM may be through the control of intestinal flora to normalize and exert anti-diabetic effect;its main active components may be lignans and terpenoids.

关键词： Schisandra sphenanthera T2DM intestinal flora HPLC

Embryo-Engineered Nonhuman Primate Models:Progress and Gap to Translational Medicine

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Research 2021年第1期2021卷 1627-1639页

作者： mei Huang jiao Yang Peng Li Yongchang Chen Yunnan Key Laboratory of Primate Biomedical Research Institute of Primate Translational MedicineKunming University of Science and TechnologyKunming 650500China State Key Laboratory of Primate Biomedical Research Kunming 650500China

Animal models of human diseases are vital in better understanding the mechanism of pathogenesis and essential for evaluating and validating potential therapeutic *** close relatives of humans,nonhuman primates(NHPs)play an increasingly indispensable role in advancing translational medicine *** this review,we summarized the progress of NHP models generated by embryo engineering,analyzed their unique advantages in mimicking clinical patients,and discussed the remaining gap between basic research of NHP models to translational medicine.

关键词： diseases Medicine translational

Extended Riccati Equation Rational Expansion Method and Its Application to Nonlinear Stochastic Evolution Equations

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Communications in Theoretical Physics 2006年第5期45卷 785-789页

作者： WANG mei-jiao WANG Qi Department of Mathematics Ningbo University Ningbo 315211 China Department of Applied Mathematics Dalian University of Technology Dalian 116024 China Key Laboratory of Mathematics Mechanization the Chinese Academy of Sciences Beijing 100080 China

In this work, by means of a new more general ansatz and the symbolic computation system Maple, we extend the Riccati equation rational expansion method [Chaos, Solitons ＆ Fractals 25 （2005） 1019] to uniformly construct a series of stochastic nontravelling wave solutions for nonlinear stochastic evolution equation. To illustrate the effectiveness of our method, we take the stochastic mKdV equation as an example, and successfully construct some new and more general solutions including a series of rational formal nontraveling wave and coefficient functions＇ soliton-like solution.s and trigonometric-like function solutions. The method can also be applied to solve other nonlinear stochastic evolution equation or equations.

关键词： extended Riccati equation rational expansion method nonlinear stochastic evolution equation stochastic mKdV equation soliton-like solutions

Electrically conductive and highly compressible anisotropic MXene-wood sponges for multifunctional and integrated wearable devices

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Journal of Materials Science & Technology 2023年第13期144卷 102-110页

作者： Dekui song mei-jiao Zeng Peng Min Xue-Qin Jia Fu-Lin Gao Zhong-Zhen Yu Xiaofeng Li State Key Laboratory of Organic-Inorganic Composites College of Materials Science and EngineeringBeijing University of Chemical TechnologyBeijing 100029China Beijing Key Laboratory of Advanced Functional Polymer Composites Beijing University of Chemical TechnologyBeijing 100029China College of Chemistry Beijing Normal UniversityBeijing100875China

Although piezoresistive sensors have wide applications in human motion detection and wearable elec-tronics,it is still a challenge to produce multifunctional and integrated sensors with wide working ranges and linear sensing ***,electrically conductive,highly compressible,and structurally anisotropic MXene-wood(MW)sponges are fabricated by converting balsa wood blocks to compressible wood sponges with extremely low density and highly anisotropic porous structure,followed by deco-rating with conductive MXene *** MW sponge is utilized to assemble a piezoresistive sensor with a large working range of 0-25 kPa,wide linear sensing ranges of 5%-50%and 0-180°,and excellent long-term reliability under a bending angle of 30°for 5000 ***,the sensor is suitable for monitoring practical human physiological signals including pulse beating,and finger and wrist *** all-MW sponge-based multifunctional and integrated sensing system is constructed by integrating the MW sponge piezoresistive sensor,the MW sponge-based solid-state supercapacitor,and the MW sponge electrophysiological *** sensing system can concurrently detect surface electromyogram and tactile pressures,and hence realize real-time closed-loop *** multifunctional and integrated MW sponge sensing system would have great potentials in real-time pressure recognition and human-machine interfaces.

关键词： MXene sheets Wood sponges Piezoresistive sensors Compressibility

Rh-catalyzed Transient Directing Group Promoted C-H Amidation of Benzaldehydes Utilizing Dioxazolones

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Chinese Journal of Chemistry 2018年第3期36卷 213-216页

作者： Xiaoyang Wang song song Ning jiao State Key Laboratory of Natural and Biomimetic Drugs School of Pharmaceutical Sciences Peking University Xue Yuan Rd. 38 Beijing 200192 China State Key Laboratory of Organometallic Chemistry Chinese Academy of Sciences Shanghai 200032 China

Transition-metal catalyzed C--H functionalization of benzaldehydes is of great interest in organic synthesis. Herein, we developed a transient directing group assisted amidation of benzaldehydes catalyzed by rhodium catalyst. With the employment of 10 mol% of 4-trifluoromethyl aniline, the in situ generated imine groups as the directing group efficiently enable this transformation. By using this protocol, a wide range of benzaldehydes were efficiently converted into the corresponding N-（2-formylphenyl）benzamides utilizing dioxazolones as the nitrogen source.

关键词： amidation benzaldehydes rhodium C--H functionalization transient directing group